This is a Validated Antibody Database (VAD) review about human CAMK4, based on 12 published articles (read how Labome selects the articles), using CAMK4 antibody in all methods. It is aimed to help Labome visitors find the most suited CAMK4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CAMK4 synonym: CaMK IV; CaMK-GR; CaMKIV; caMK

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • western blot knockout validation; mouse; 1:100; fig s2a
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1e
Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz, sc-55501) was used in western blot knockout validation on mouse samples at 1:100 (fig s2a) and in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1e). Nat Commun (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • western blot knockout validation; mouse; 1:100; fig s2a
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1e
Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz, sc-55501) was used in western blot knockout validation on mouse samples at 1:100 (fig s2a) and in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1e). Nat Commun (2022) ncbi
mouse monoclonal (26)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1a
Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz Biotechnology, sc-136249) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1a). Eneuro (2021) ncbi
mouse monoclonal (26)
  • western blot; mouse; 1:500; fig 3
In order to assess induction of synaptic impairment and memory deficit by calcieurin-mediated inactivation of nuclear CaMKIV/CREB signaling due to tau accumulation, Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz, sc-136249) was used in western blot on mouse samples at 1:500 (fig 3). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (A-3)
  • western blot; rat; fig 5
Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz, sc-166156) was used in western blot on rat samples (fig 5). Autophagy (2015) ncbi
mouse monoclonal (26)
  • immunocytochemistry; rat; 1:500; fig 3
In order to review the mechanism of a gammaCaMKII-CaM nuclear translocation, Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz, sc-136249) was used in immunocytochemistry on rat samples at 1:500 (fig 3). Biochem Biophys Res Commun (2015) ncbi
mouse monoclonal (H-5)
  • western blot; mouse; 1:1000; loading ...; fig 4c
Santa Cruz Biotechnology CAMK4 antibody (Santa Cruz Biotechnology, sc-55501) was used in western blot on mouse samples at 1:1000 (fig 4c). PLoS ONE (2014) ncbi
Abcam
domestic rabbit monoclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a, s1a
  • flow cytometry; human; 1:100; fig s1c
  • immunoprecipitation; human; loading ...; fig 8e
  • western blot; human; loading ...; fig 5g, 8e
Abcam CAMK4 antibody (Abcam, ab68218) was used in immunohistochemistry - paraffin section on human samples (fig 1a, s1a), in flow cytometry on human samples at 1:100 (fig s1c), in immunoprecipitation on human samples (fig 8e) and in western blot on human samples (fig 5g, 8e). Nat Commun (2022) ncbi
domestic rabbit monoclonal (EP2564Y)
  • immunocytochemistry; rat; 1:250; fig 5
  • western blot; rat; 1:2000; fig 5
Abcam CAMK4 antibody (Abcam, ab75874) was used in immunocytochemistry on rat samples at 1:250 (fig 5) and in western blot on rat samples at 1:2000 (fig 5). PLoS ONE (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 4
Cell Signaling Technology CAMK4 antibody (Cell signaling, 4032) was used in western blot on rat samples at 1:1000 (fig 4). Exp Ther Med (2016) ncbi
BD Biosciences
mouse monoclonal (26/CaM Kinase IV)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1a
BD Biosciences CAMK4 antibody (BD Biosciences, 610275) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1a). Eneuro (2021) ncbi
mouse monoclonal (26/CaM Kinase IV)
  • western blot; human; loading ...; fig 9a
  • immunohistochemistry; mouse; fig 4c
BD Biosciences CAMK4 antibody (BD Biosciences, 610276) was used in western blot on human samples (fig 9a) and in immunohistochemistry on mouse samples (fig 4c). J Clin Invest (2018) ncbi
mouse monoclonal (26/CaM Kinase IV)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences CAMK4 antibody (BD, 26) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (26/CaM Kinase IV)
  • western blot; mouse
BD Biosciences CAMK4 antibody (BD Biosciences, 610275) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (26/CaM Kinase IV)
  • western blot; mouse; 1:250
BD Biosciences CAMK4 antibody (transduction laboratories, 610275) was used in western blot on mouse samples at 1:250. Mol Neurobiol (2014) ncbi
Articles Reviewed
  1. Yong L, Yu Y, Li B, Ge H, Zhen Q, Mao Y, et al. Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice. Nat Commun. 2022;13:4255 pubmed publisher
  2. Trojanowski N, Turrigiano G. CaMKIV Signaling Is Not Essential for the Maintenance of Intrinsic or Synaptic Properties in Mouse Visual Cortex. Eneuro. 2021;8: pubmed publisher
  3. Maeda K, Otomo K, Yoshida N, Abu Asab M, Ichinose K, Nishino T, et al. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. J Clin Invest. 2018;128:3445-3459 pubmed publisher
  4. Yan X, Liu J, Ye Z, Huang J, He F, Xiao W, et al. CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. PLoS ONE. 2016;11:e0162784 pubmed publisher
  5. Zhang Y, Lin R, Tao J, Wu Y, Chen B, Yu K, et al. Electroacupuncture improves cognitive ability following cerebral ischemia reperfusion injury via CaM-CaMKIV-CREB signaling in the rat hippocampus. Exp Ther Med. 2016;12:777-782 pubmed
  6. Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed publisher
  7. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  8. Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
  9. Cohen S, Li B, Tsien R, Ma H. Evolutionary and functional perspectives on signaling from neuronal surface to nucleus. Biochem Biophys Res Commun. 2015;460:88-99 pubmed publisher
  10. Watanabe S, Horie T, Nagao K, Kuwabara Y, Baba O, Nishi H, et al. Cardiac-specific inhibition of kinase activity in calcium/calmodulin-dependent protein kinase kinase-β leads to accelerated left ventricular remodeling and heart failure after transverse aortic constriction in mice. PLoS ONE. 2014;9:e108201 pubmed publisher
  11. Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPK?2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed publisher
  12. Alzoubi K, Alkadhi K. Chronic nicotine treatment reverses hypothyroidism-induced impairment of L-LTP induction phase: critical role of CREB. Mol Neurobiol. 2014;49:1245-55 pubmed publisher