This is a Validated Antibody Database (VAD) review about
human C5AR1, based on 15 published articles (
read how Labome selects the articles), using C5AR1 antibody in all methods. It is aimed to help Labome visitors find the most suited C5AR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
C5AR1 synonym: C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a-R; complement component 5 receptor 1; complement component 5a receptor 1
Santa Cruz Biotechnology
| mouse monoclonal (B-6) | - western blot; human; loading ...; fig 2a
| Santa Cruz Biotechnology C5AR1 antibody (Santa Cruz, sc-271949) was used in western blot on human samples (fig 2a). Biosci Rep (2018) ncbi |
| mouse monoclonal (R63) | - immunocytochemistry; human; fig 6d
| Santa Cruz Biotechnology C5AR1 antibody (Santa Cruz, SC-53797) was used in immunocytochemistry on human samples (fig 6d). Toxins (Basel) (2017) ncbi |
| mouse monoclonal (32-G1) | - immunocytochemistry; human; fig 1a
| Santa Cruz Biotechnology C5AR1 antibody (Santa-Cruz, sc-53793) was used in immunocytochemistry on human samples (fig 1a). Toxins (Basel) (2017) ncbi |
| mouse monoclonal (S5/1) | - western blot; human; loading ...; fig 1c
| In order to investigate the contribution of NLRP3 inflammasome activity to the T helper cell 1 response, Santa Cruz Biotechnology C5AR1 antibody (Santa Cruz Biotechnology, sc-53795) was used in western blot on human samples (fig 1c). Science (2016) ncbi |
BioLegend
| mouse monoclonal (S5/1) | - flow cytometry; human; fig 3a
| BioLegend C5AR1 antibody (Biolegend, S5/1) was used in flow cytometry on human samples (fig 3a). Front Immunol (2017) ncbi |
| mouse monoclonal (S5/1) | - flow cytometry; human; fig 4b
| BioLegend C5AR1 antibody (BioLegend, S5/1) was used in flow cytometry on human samples (fig 4b). J Infect (2017) ncbi |
| mouse monoclonal (S5/1) | - blocking or activating experiments; human; loading ...; fig 1a
| BioLegend C5AR1 antibody (BioLegend, S5/1) was used in blocking or activating experiments on human samples (fig 1a). Sci Rep (2016) ncbi |
| mouse monoclonal (S5/1) | - flow cytometry; human; fig 3
| BioLegend C5AR1 antibody (BioLegend, S5/1) was used in flow cytometry on human samples (fig 3). J Immunol (2015) ncbi |
Bio-Rad
| mouse monoclonal (P12/1) | - immunocytochemistry; human; loading ...; fig 1d
| In order to investigate the contribution of NLRP3 inflammasome activity to the T helper cell 1 response, Bio-Rad C5AR1 antibody (AbD Serotec, MCA2059) was used in immunocytochemistry on human samples (fig 1d). Science (2016) ncbi |
| mouse monoclonal (S5/1) | - blocking or activating experiments; human; fig 4
| Bio-Rad C5AR1 antibody (AbD Serotec, S5/1) was used in blocking or activating experiments on human samples (fig 4). J Immunol (2015) ncbi |
| mouse monoclonal (S5/1) | - immunohistochemistry - paraffin section; human; 1:100
- western blot; human; 1:500
| Bio-Rad C5AR1 antibody (Serotec, MCA1283T) was used in immunohistochemistry - paraffin section on human samples at 1:100 and in western blot on human samples at 1:500. Lung Cancer (2013) ncbi |
LifeSpan Biosciences
| rat monoclonal (20/70) | - flow cytometry; mouse; fig 5
| LifeSpan Biosciences C5AR1 antibody (LifeSpan Biosciences, 20/70) was used in flow cytometry on mouse samples (fig 5). J Immunol (2015) ncbi |
Bioworld
| polyclonal | - western blot; human; loading ...; fig 2a
| Bioworld C5AR1 antibody (Bioworld Technology, P21730) was used in western blot on human samples (fig 2a). Oncogene (2018) ncbi |
BD Biosciences
| monoclonal (20/70) | - flow cytometry; mouse; fig s7d
| BD Biosciences C5AR1 antibody (BD Biosciences, 20/70) was used in flow cytometry on mouse samples (fig s7d). J Clin Invest (2018) ncbi |
| mouse monoclonal (D53-1473) | - flow cytometry; human; 1:5; fig 5
| BD Biosciences C5AR1 antibody (BD Bioscience, 550494) was used in flow cytometry on human samples at 1:5 (fig 5). Oncotarget (2016) ncbi |
| rabbit monoclonal (C85-4124) | - flow cytometry; human; fig st1
| In order to find cell-surface markers specific to human neutrophils, BD Biosciences C5AR1 antibody (BD, 552993) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi |
Hycult Biotech
| mouse monoclonal (561) | - ELISA; human; 2 ug/ml; fig 2f
| In order to monitor complement activation after eculizumab treatment, Hycult Biotech C5AR1 antibody (Hycult Biotech, 561) was used in ELISA on human samples at 2 ug/ml (fig 2f). Clin Exp Immunol (2017) ncbi |
Keszei M, Record J, Kritikou J, Wurzer H, Geyer C, Thiemann M,
et al. Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive. J Clin Invest. 2018;128:4115-4131
pubmed publisher Zhao C, Li Y, Qiu W, He F, Zhang W, Zhao D,
et al. C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation. Oncogene. 2018;37:4821-4837
pubmed publisher Zhang Y, Cao Y, Zhang L, Feng C, Zhou G, Wen G. Apigenin inhibits C5a-induced proliferation of human nasopharyngeal carcinoma cells through down-regulation of C5aR. Biosci Rep. 2018;38:
pubmed publisher Jeong J, Hong S, Kwon O, Ghang B, Hwang I, Kim Y,
et al. CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis. Front Immunol. 2017;8:1260
pubmed publisher Gillman A, Breshears L, Kistler C, Finnegan P, Torres V, Schlievert P,
et al. Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel). 2017;9:
pubmed publisher Janesch P, Rouha H, Weber S, Malafa S, Gross K, Maierhofer B,
et al. Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8. J Infect. 2017;74:473-483
pubmed publisher Zimmermann Meisse G, Prevost G, Jover E. Above and beyond C5a Receptor Targeting by Staphylococcal Leucotoxins: Retrograde Transport of Panton-Valentine Leucocidin and ?-Hemolysin. Toxins (Basel). 2017;9:
pubmed publisher Wehling C, Amon O, Bommer M, Hoppe B, Kentouche K, Schalk G,
et al. Monitoring of complement activation biomarkers and eculizumab in complement-mediated renal disorders. Clin Exp Immunol. 2017;187:304-315
pubmed publisher Wang X, Qin W, Zhang Y, Zhang H, Sun B. Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway. Oncotarget. 2016;7:74247-74258
pubmed publisher An L, Gorman J, Stephens G, Swerdlow B, Warrener P, Bonnell J,
et al. Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways. Sci Rep. 2016;6:33346
pubmed publisher Arbore G, West E, Spolski R, Robertson A, Klos A, Rheinheimer C,
et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⺠T cells. Science. 2016;352:aad1210
pubmed publisher Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9
pubmed publisher Mehta G, Scheinman R, Holers V, Banda N. A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA. J Immunol. 2015;194:5446-54
pubmed publisher Hünniger K, Bieber K, Martin R, Lehnert T, Figge M, Löffler J,
et al. A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. J Immunol. 2015;194:1199-210
pubmed publisher Gu J, Ding J, Lu C, Lin Z, Chu Y, Zhao G,
et al. Overexpression of CD88 predicts poor prognosis in non-small-cell lung cancer. Lung Cancer. 2013;81:259-65
pubmed publisher
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
