This is a Validated Antibody Database (VAD) review about human C1QA, based on 13 published articles (read how Labome selects the articles), using C1QA antibody in all methods. It is aimed to help Labome visitors find the most suited C1QA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (4.8)
  • western blot; mouse; loading ...; fig 2b
Abcam C1QA antibody (Abcam, ab182451) was used in western blot on mouse samples (fig 2b). Acta Neuropathol Commun (2022) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry; mouse; 1:1500; loading ...; fig 3s1a
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry on mouse samples at 1:1500 (fig 3s1a). elife (2022) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry; mouse; loading ...
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry on mouse samples . Cell Rep (2021) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry; mouse; ; loading ...; fig 1c
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry on mouse samples at (fig 1c). Acta Neuropathol (2021) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5e
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry on mouse samples at 1:500 (fig 5e). Acta Neuropathol Commun (2021) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4a
  • flow cytometry; mouse; fig 4f
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry - frozen section on mouse samples (fig 4a) and in flow cytometry on mouse samples (fig 4f). J Neuroinflammation (2021) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 2a
Abcam C1QA antibody (Abcam, 4.8) was used in immunohistochemistry - free floating section on mouse samples at 1:100 (fig 2a). Radiat Res (2020) ncbi
domestic rabbit monoclonal (EPR14634)
  • western blot; rat; 1:500; loading ...; fig 7a
  • western blot; rhesus macaque; 1:500; loading ...; fig 6a, 6b
Abcam C1QA antibody (Abcam, ab189922) was used in western blot on rat samples at 1:500 (fig 7a) and in western blot on rhesus macaque samples at 1:500 (fig 6a, 6b). J Neuroinflammation (2020) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3g
Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 3g). Acta Neuropathol (2019) ncbi
domestic rabbit monoclonal (EPR2980Y)
  • immunohistochemistry; human; 1:50; loading ...; fig 5b
Abcam C1QA antibody (Abcam, ab76425) was used in immunohistochemistry on human samples at 1:50 (fig 5b). Cell Mol Gastroenterol Hepatol (2018) ncbi
domestic rabbit monoclonal
  • western blot; human; 1:500; loading ...; fig 7a
Abcam C1QA antibody (Abcam, ab108325) was used in western blot on human samples at 1:500 (fig 7a). Cell Mol Gastroenterol Hepatol (2018) ncbi
rat monoclonal (7H8)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 6c
In order to see that the granulin Alzheimer's disease risk variant has no significant effects on florbetapir positron emission tomographic amyloid imaging and cerebrospinal fluid Abeta levels, Abcam C1QA antibody (Abcam, ab11861) was used in immunohistochemistry on mouse samples at 1:50 (fig 6c). Acta Neuropathol (2017) ncbi
domestic rabbit monoclonal (4.8)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6c
In order to see that the granulin Alzheimer's disease risk variant has no significant effects on florbetapir positron emission tomographic amyloid imaging and cerebrospinal fluid Abeta levels, Abcam C1QA antibody (Abcam, ab182451) was used in immunohistochemistry on mouse samples at 1:1000 (fig 6c). Acta Neuropathol (2017) ncbi
Invitrogen
mouse monoclonal (JL-1)
  • immunohistochemistry; mouse; 1:250
In order to investigate hypercholesterolemia at various stages of Alzheimer's disease, Invitrogen C1QA antibody (Thermo, MA1-40312) was used in immunohistochemistry on mouse samples at 1:250. Mol Cell Neurosci (2014) ncbi
Quidel
  • blocking or activating experiments; rat; loading ...; fig s3d
In order to identify an astrocyte subtype induced by activated microglia, Quidel C1QA antibody (Quidel, A301) was used in blocking or activating experiments on rat samples (fig s3d). Nature (2017) ncbi
Articles Reviewed
  1. Carpanini S, Torvell M, Bevan R, Byrne R, Daskoulidou N, Saito T, et al. Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models. Acta Neuropathol Commun. 2022;10:99 pubmed publisher
  2. ANDERSON S, Roberts J, Ghena N, Irvin E, Schwakopf J, Cooperstein I, et al. Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence. elife. 2022;11: pubmed publisher
  3. Wani A, Zhu J, ULRICH J, Eteleeb A, Sauerbeck A, Reitz S, et al. Neuronal VCP loss of function recapitulates FTLD-TDP pathology. Cell Rep. 2021;36:109399 pubmed publisher
  4. Ramaglia V, Dubey M, Malpede M, Petersen N, de Vries S, Ahmed S, et al. Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory. Acta Neuropathol. 2021;142:643-667 pubmed publisher
  5. Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed publisher
  6. Fairley L, Sahara N, Aoki I, Ji B, Suhara T, Higuchi M, et al. Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy. J Neuroinflammation. 2021;18:76 pubmed publisher
  7. Montay Gruel P, Markarian M, Allen B, Baddour J, Giedzinski E, Jorge P, et al. Ultra-High-Dose-Rate FLASH Irradiation Limits Reactive Gliosis in the Brain. Radiat Res. 2020;194:636-645 pubmed publisher
  8. Datta D, Leslie S, Morozov Y, Duque A, Rakic P, van Dyck C, et al. Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex. J Neuroinflammation. 2020;17:8 pubmed publisher
  9. Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed publisher
  10. Duggan S, Garry C, Behan F, Phipps S, Kudo H, Kirca M, et al. siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth. Cell Mol Gastroenterol Hepatol. 2018;5:569-590 pubmed publisher
  11. Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed publisher
  12. Takahashi H, Klein Z, Bhagat S, Kaufman A, Kostylev M, Ikezu T, et al. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017;133:785-807 pubmed publisher
  13. Hohsfield L, Daschil N, Orädd G, Strömberg I, Humpel C. Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models. Mol Cell Neurosci. 2014;63:83-95 pubmed