This is a Validated Antibody Database (VAD) review about human BIN1, based on 9 published articles (read how Labome selects the articles), using BIN1 antibody in all methods. It is aimed to help Labome visitors find the most suited BIN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BIN1 synonym: AMPH2; AMPHL; CNM2; SH3P9

Abcam
domestic rabbit monoclonal (EPR13463-25)
  • immunohistochemistry - free floating section; mouse; loading ...; fig s4
  • western blot; mouse; loading ...; fig 4a
Abcam BIN1 antibody (Abcam, ab185950) was used in immunohistochemistry - free floating section on mouse samples (fig s4) and in western blot on mouse samples (fig 4a). J Biol Chem (2019) ncbi
domestic rabbit monoclonal (EPR13463)
  • western blot; human; 1:1000; loading ...; fig 6d
Abcam BIN1 antibody (Abcam, ab182562) was used in western blot on human samples at 1:1000 (fig 6d). Nat Commun (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (99D)
  • immunocytochemistry; African green monkey; 1:500; loading ...; fig 3b
Santa Cruz Biotechnology BIN1 antibody (Santa Cruz, sc-13575) was used in immunocytochemistry on African green monkey samples at 1:500 (fig 3b). J Cell Sci (2017) ncbi
mouse monoclonal (2F11)
  • immunohistochemistry - frozen section; mouse; 1:100; fig 4
In order to study the role of vesicle trafficking and cytoskeletal reorganization in the mechanism by which EHD1 mediates normal muscle development, Santa Cruz Biotechnology BIN1 antibody (Santa Cruz, sc-23918) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 4). Dev Biol (2014) ncbi
Proteintech Group
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4a
Proteintech Group BIN1 antibody (Proteintech, 14647-1) was used in western blot on mouse samples (fig 4a). J Biol Chem (2019) ncbi
EMD Millipore
mouse monoclonal (99D)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3j
  • western blot; mouse; loading ...; tbl 1
In order to elucidate the contribution of the Sac phosphatase domain of Synaptojanin 1 to neurological symptoms, EMD Millipore BIN1 antibody (Millipore, 05-449) was used in immunohistochemistry - frozen section on mouse samples (fig 3j) and in western blot on mouse samples (tbl 1). Neuron (2017) ncbi
mouse monoclonal (99D)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 4e
In order to demonstrate that Bin1 and CD2AP keep APP and BACE1 apart in early endosomes by distinct mechanisms in axon and dendrites, EMD Millipore BIN1 antibody (Millipore, 05-449) was used in immunocytochemistry on mouse samples at 1:100 (fig 4e). EMBO Rep (2017) ncbi
mouse monoclonal (99D)
  • immunohistochemistry - paraffin section; human; 1:3200; fig 3
In order to characterize the cerebral cortex during the progression of Alzheimer disease pathology by visualizing subcellular changes in bridging integrator 1 protein expression, EMD Millipore BIN1 antibody (Millipore, 05-449) was used in immunohistochemistry - paraffin section on human samples at 1:3200 (fig 3). J Neuropathol Exp Neurol (2016) ncbi
mouse monoclonal (99D)
  • immunohistochemistry; mouse; loading ...; fig 4a
EMD Millipore BIN1 antibody (Merck, 99D) was used in immunohistochemistry on mouse samples (fig 4a). J Cell Biol (2015) ncbi
mouse monoclonal (99D)
  • western blot; human
In order to study the relationship of an Alzheimer's disease-linked SNP in the CLU gene and Tau, EMD Millipore BIN1 antibody (Millipore, 05-449) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Andrew R, de Rossi P, Nguyen P, Kowalski H, Recupero A, Guerbette T, et al. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model. J Biol Chem. 2019;294:4477-4487 pubmed publisher
  2. Ge Y, Schuster M, Pundhir S, Rapin N, Bagger F, Sidiropoulos N, et al. The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Nat Commun. 2019;10:172 pubmed publisher
  3. Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher
  4. Hofhuis J, Bersch K, Büssenschütt R, Drzymalski M, Liebetanz D, Nikolaev V, et al. Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy. J Cell Sci. 2017;130:841-852 pubmed publisher
  5. Ubelmann F, Burrinha T, Salavessa L, Gomes R, Ferreira C, Moreno N, et al. Bin1 and CD2AP polarise the endocytic generation of beta-amyloid. EMBO Rep. 2017;18:102-122 pubmed publisher
  6. Adams S, Tilton K, Kozubek J, Seshadri S, Delalle I. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. J Neuropathol Exp Neurol. 2016;75:779-790 pubmed
  7. Lo H, Nixon S, Hall T, Cowling B, Ferguson C, Morgan G, et al. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol. 2015;210:833-49 pubmed publisher
  8. Zhou Y, Hayashi I, Wong J, Tugusheva K, Renger J, Zerbinatti C. Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease. PLoS ONE. 2014;9:e103187 pubmed publisher
  9. Posey A, Swanson K, Alvarez M, Krishnan S, Earley J, Band H, et al. EHD1 mediates vesicle trafficking required for normal muscle growth and transverse tubule development. Dev Biol. 2014;387:179-90 pubmed publisher