This is a Validated Antibody Database (VAD) review about human BAP1, based on 21 published articles (read how Labome selects the articles), using BAP1 antibody in all methods. It is aimed to help Labome visitors find the most suited BAP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BAP1 synonym: HUCEP-13; UCHL2; hucep-6

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot knockout validation; human; loading ...; fig 3h
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in western blot knockout validation on human samples (fig 3h). Nat Med (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot; rat; loading ...
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in western blot on rat samples . Redox Biol (2022) ncbi
mouse monoclonal (C-4)
  • western blot; human; 1:1000; fig 2
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in western blot on human samples at 1:1000 (fig 2). Int J Mol Sci (2021) ncbi
mouse monoclonal (C-4)
  • western blot; human; 1:2000; loading ...; fig s5g
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in western blot on human samples at 1:2000 (fig s5g). Nat Commun (2020) ncbi
mouse monoclonal (C-4)
  • western blot; human; 1:1000; loading ...; fig 1a
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz Biotechnology Inc, sc-28383) was used in western blot on human samples at 1:1000 (fig 1a). Nat Cell Biol (2018) ncbi
mouse monoclonal (C-4)
  • other; human; loading ...; fig 4c
Santa Cruz Biotechnology BAP1 antibody (SantaCruz, sc-28383) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (C-4)
  • western blot; human; loading ...; fig 1d
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, C-4) was used in western blot on human samples (fig 1d). Nature (2017) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig 1d
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, C-4) was used in western blot on human samples (fig 1d). Nature (2017) ncbi
mouse monoclonal (C-4)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (C-4)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Santa Cruz Biotechnology BAP1 antibody (SantaCruz, sc-28383) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (C-4)
  • immunohistochemistry; human; loading ...; tbl 2
In order to characterize malignant pleural mesothelioma xenoplants as preclinical models, Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, C-4) was used in immunohistochemistry on human samples (tbl 2). Clin Cancer Res (2017) ncbi
mouse monoclonal
  • immunohistochemistry; human; loading ...; tbl 2
In order to characterize malignant pleural mesothelioma xenoplants as preclinical models, Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, C-4) was used in immunohistochemistry on human samples (tbl 2). Clin Cancer Res (2017) ncbi
mouse monoclonal (C-4)
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (3C11)
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 2
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-13576) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (C-4)
  • immunohistochemistry - free floating section; human; 1:50; fig s3
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in immunohistochemistry - free floating section on human samples at 1:50 (fig s3). Mod Pathol (2016) ncbi
mouse monoclonal (C-4)
  • western blot knockout validation; human; loading ...; fig 3h
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in western blot knockout validation on human samples (fig 3h). Nat Med (2015) ncbi
mouse monoclonal (C-4)
  • immunoprecipitation; human; fig 3
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 6
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz Biotechnology, sc 28383) was used in immunoprecipitation on human samples (fig 3), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (C-4)
  • immunoprecipitation; human; fig 1b
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz Biotechnology, sc-28383) was used in immunoprecipitation on human samples (fig 1b). J Biol Chem (2015) ncbi
mouse monoclonal (C-4)
  • immunohistochemistry - paraffin section; human; 1:100; fig 5
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 2
Santa Cruz Biotechnology BAP1 antibody (Santa Cruz, sc-28383) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5), in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 2). Cancer Sci (2015) ncbi
mouse monoclonal (C-4)
  • western blot; human; fig 3a
Santa Cruz Biotechnology BAP1 antibody (Santa cruz, sc-28383) was used in western blot on human samples (fig 3a). Epigenetics (2015) ncbi
mouse monoclonal (C-4)
  • immunohistochemistry; human; 1:50
Santa Cruz Biotechnology BAP1 antibody (Santa, sc-28383) was used in immunohistochemistry on human samples at 1:50. Urol Oncol (2015) ncbi
mouse monoclonal (C-4)
  • chromatin immunoprecipitation; human
  • immunoprecipitation; human
  • immunocytochemistry; human; fig 2c
  • western blot; human
Santa Cruz Biotechnology BAP1 antibody (Santa, SC-28383) was used in chromatin immunoprecipitation on human samples , in immunoprecipitation on human samples , in immunocytochemistry on human samples (fig 2c) and in western blot on human samples . Nucleic Acids Res (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
Abcam BAP1 antibody (Abcam, ab199396) was used in western blot on human samples at 1:1000 (fig 5a). Cancer Cell Int (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5m
Cell Signaling Technology BAP1 antibody (Cell Signaling, 9373) was used in western blot on human samples at 1:1000 (fig 5m). Cancer Res (2018) ncbi
Articles Reviewed
  1. Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
  2. Mergener S, Siveke J, Peña Llopis S. Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma. Int J Mol Sci. 2021;22: pubmed publisher
  3. Chen J, Xu D, Cao J, Zuo L, Han Z, Tian Y, et al. TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination. Cancer Cell Int. 2021;21:129 pubmed publisher
  4. Perkail S, Andricovich J, Kai Y, Tzatsos A. BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice. Nat Commun. 2020;11:3018 pubmed publisher
  5. Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher
  6. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  7. Jung Y, Cackowski F, Yumoto K, Decker A, Wang J, Kim J, et al. CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes. Cancer Res. 2018;78:2026-2039 pubmed publisher
  8. Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  11. Wu L, Allo G, John T, Li M, Tagawa T, Opitz I, et al. Patient-Derived Xenograft Establishment from Human Malignant Pleural Mesothelioma. Clin Cancer Res. 2017;23:1060-1067 pubmed publisher
  12. Tayao M, Andrici J, Farzin M, Clarkson A, Sioson L, Watson N, et al. Loss of BAP1 Expression Is Very Rare in Pancreatic Ductal Adenocarcinoma. PLoS ONE. 2016;11:e0150338 pubmed publisher
  13. Valletta S, Dolatshad H, Bartenstein M, Yip B, Bello E, Gordon S, et al. ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts. Oncotarget. 2015;6:44061-71 pubmed publisher
  14. Ho T, Kapur P, Joseph R, Serie D, Eckel Passow J, Tong P, et al. Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death. Mod Pathol. 2016;29:34-42 pubmed publisher
  15. Lafave L, Beguelin W, Koche R, Teater M, Spitzer B, Chramiec A, et al. Loss of BAP1 function leads to EZH2-dependent transformation. Nat Med. 2015;21:1344-9 pubmed publisher
  16. Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher
  17. Daou S, Hammond Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono N, et al. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015;290:28643-63 pubmed publisher
  18. Mori T, Sumii M, Fujishima F, Ueno K, Emi M, Nagasaki M, et al. Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma. Cancer Sci. 2015;106:1118-29 pubmed publisher
  19. Gagnon J, Daou S, Zamorano N, Iannantuono N, Hammond Martel I, Mashtalir N, et al. Undetectable histone O-GlcNAcylation in mammalian cells. Epigenetics. 2015;10:677-91 pubmed publisher
  20. Ho T, Kapur P, Joseph R, Serie D, Eckel Passow J, Parasramka M, et al. Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma. Urol Oncol. 2015;33:23.e9-23.e14 pubmed publisher
  21. Ji Z, Mohammed H, Webber A, Ridsdale J, Han N, Carroll J, et al. The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. Nucleic Acids Res. 2014;42:6232-42 pubmed publisher