This is a Validated Antibody Database (VAD) review about human B7 H3, based on 9 published articles (read how Labome selects the articles), using B7 H3 antibody in all methods. It is aimed to help Labome visitors find the most suited B7 H3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
B7 H3 synonym: 4Ig-B7-H3; B7-H3; B7H3; B7RP-2

BioLegend
mouse monoclonal (DCN.70)
  • flow cytometry; human; loading ...; fig 3b
BioLegend B7 H3 antibody (BioLegend, 331606) was used in flow cytometry on human samples (fig 3b). Cancers (Basel) (2021) ncbi
mouse monoclonal (MIH42)
  • flow cytometry; mouse; 1:100; fig 1k
BioLegend B7 H3 antibody (Biolegend, 351003) was used in flow cytometry on mouse samples at 1:100 (fig 1k). Nat Commun (2021) ncbi
mouse monoclonal (MIH42)
  • immunohistochemistry; human; loading ...; fig 10e
BioLegend B7 H3 antibody (Biolegend, MIH42) was used in immunohistochemistry on human samples (fig 10e). Bone Rep (2020) ncbi
mouse monoclonal (MIH42)
  • flow cytometry; human; loading ...; fig s5a
BioLegend B7 H3 antibody (Biolegend, MIH42) was used in flow cytometry on human samples (fig s5a). JCI Insight (2018) ncbi
mouse monoclonal (DCN.70)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BioLegend B7 H3 antibody (BioLegen d, 331606) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
Abcam
mouse monoclonal (6A1)
  • immunohistochemistry; human; 1:200; fig 2a
Abcam B7 H3 antibody (Abcam, ab105922) was used in immunohistochemistry on human samples at 1:200 (fig 2a). Reprod Biol Endocrinol (2021) ncbi
mouse monoclonal (6A1)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1b
  • western blot; human; 1:500; loading ...; fig 4b
Abcam B7 H3 antibody (Abcam, ab105922) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1b) and in western blot on human samples at 1:500 (fig 4b). Cancer Sci (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; fig s1b
Invitrogen B7 H3 antibody (ThermoFisher Scientific, PA551098) was used in western blot on mouse samples (fig s1b). Sci Rep (2019) ncbi
mouse monoclonal (6A1)
  • other; human; fig 7
In order to characterize the potent antitumor activity and binding to the FG loop of tumor antigen B7-H3 of humanized affinity-matured monoclonal antibody 8H9, Invitrogen B7 H3 antibody (Thermo Scientific, 6A1) was used in other on human samples (fig 7). J Biol Chem (2015) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; human; 1:1000; fig 4a
R&D Systems B7 H3 antibody (R&D System, AF1027) was used in immunohistochemistry on human samples at 1:1000 (fig 4a). Cancers (Basel) (2021) ncbi
Articles Reviewed
  1. Lavoie R, Gargollo P, Ahmed M, Kim Y, Baer E, Phelps D, et al. Surfaceome Profiling of Rhabdomyosarcoma Reveals B7-H3 as a Mediator of Immune Evasion. Cancers (Basel). 2021;13: pubmed publisher
  2. Qin X, Sun W, Wang C, Li M, Zhao X, Li C, et al. Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis. Reprod Biol Endocrinol. 2021;19:114 pubmed publisher
  3. Muranushi R, Araki K, Yokobori T, Chingunjav B, Hoshino K, Dolgormaa G, et al. High membrane expression of CMTM6 in hepatocellular carcinoma is associated with tumor recurrence. Cancer Sci. 2021;112:3314-3323 pubmed publisher
  4. Arenas E, Martínez Sabadell A, Rius Ruiz I, Román Alonso M, Escorihuela M, Luque A, et al. Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nat Commun. 2021;12:1237 pubmed publisher
  5. Zhang Z, Le K, La Placa D, Armstrong B, Miller M, Shively J. CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils. Bone Rep. 2020;12:100237 pubmed publisher
  6. Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed publisher
  7. Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed publisher
  8. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  9. Ahmed M, Cheng M, Zhao Q, Goldgur Y, Cheal S, Guo H, et al. Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3. J Biol Chem. 2015;290:30018-29 pubmed publisher