This is a Validated Antibody Database (VAD) review about human Apg3p, based on 21 published articles (read how Labome selects the articles), using Apg3p antibody in all methods. It is aimed to help Labome visitors find the most suited Apg3p antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Apg3p synonym: APG3; APG3-LIKE; APG3L; PC3-96; ubiquitin-like-conjugating enzyme ATG3; 2610016C12Rik; APG3 autophagy 3-like; ATG3 autophagy related 3 homolog; autophagy-related protein 3; hApg3

Knockout validation
Abcam
rabbit monoclonal (EPR4801)
  • western blot knockout validation; mouse; loading ...; fig 3
Abcam Apg3p antibody (Abcam, EPR4801) was used in western blot knockout validation on mouse samples (fig 3). Viruses (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s1d
Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot knockout validation on mouse samples (fig s1d). Cell Death Dis (2016) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig 3b
In order to uncover a role for ATG12-ATG3 in late endosome function that is distinct from autophagy, Sigma-Aldrich Apg3p antibody (Sigma, A3231) was used in western blot knockout validation on mouse samples at 1:500 (fig 3b). Nat Cell Biol (2015) ncbi
Abcam
rabbit monoclonal (EPR4801)
  • western blot knockout validation; mouse; loading ...; fig 3
Abcam Apg3p antibody (Abcam, EPR4801) was used in western blot knockout validation on mouse samples (fig 3). Viruses (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3i
In order to study the promotion of lysosomal biogenesis and autophagy by nucleus-translocated ACSS2, Cell Signaling Technology Apg3p antibody (Cell signaling, 3415) was used in western blot on human samples (fig 3i). Mol Cell (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig s2b
In order to investigate the role of inositol-requiring enzyme-1 alpha in glomerular capillary integrity and autophagy in podocytes, Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in western blot on mouse samples (fig s2b). Mol Biol Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 10c
Cell Signaling Technology Apg3p antibody (CST, 3415) was used in western blot on human samples (fig 10c). elife (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 2b
Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in western blot on rat samples at 1:1000 (fig 2b). Mol Med Rep (2017) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s1d
Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot knockout validation on mouse samples (fig s1d). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 8
In order to study a novel therapeutic strategy for Alzheimer's disease via Pim1 inhibition, Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in western blot on mouse samples at 1:1000 (fig 8). Mol Neurodegener (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415P) was used in western blot on human samples (fig 7b). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in western blot on human samples (fig 4). Onco Targets Ther (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to report that glucocorticoid receptor activation and PPAR-gamma inactivation mediate BAY 11-7085-induced autophagy, Cell Signaling Technology Apg3p antibody (Cell signaling, 3415) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 7
In order to investigate Alzheimer's Disease in a mouse model where ribosomal protein S6 kinase is decreased, Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot on mouse samples at 1:1000 (fig 7). J Neurosci (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; rat
Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415) was used in immunocytochemistry on human samples and in western blot on rat samples . Toxicol Lett (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
In order to elucidate how PLK1 regulates cell survival during mTORC1 hyperactivation, Cell Signaling Technology Apg3p antibody (Cell signaling, 3415) was used in western blot on human samples (fig 5). Cell Cycle (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology Apg3p antibody (Cell Signaling, 3415P) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot on mouse samples . Cell Physiol Biochem (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the pathogenesis of cardiomyopathy in Friedreich ataxia, Cell Signaling Technology Apg3p antibody (Cell Signaling Technology, 3415) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
MBL International
mouse monoclonal (300000000)
  • western blot; human; loading ...
MBL International Apg3p antibody (MBL International, M133-3) was used in western blot on human samples . Sci Rep (2017) ncbi
mouse monoclonal (300000000)
  • western blot; human; loading ...; fig 1a
  • immunoprecipitation; mouse
  • western blot; mouse
MBL International Apg3p antibody (MBL, M133?C3) was used in western blot on human samples (fig 1a), in immunoprecipitation on mouse samples and in western blot on mouse samples . Autophagy (2017) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig 3b
In order to uncover a role for ATG12-ATG3 in late endosome function that is distinct from autophagy, Sigma-Aldrich Apg3p antibody (Sigma, A3231) was used in western blot knockout validation on mouse samples at 1:500 (fig 3b). Nat Cell Biol (2015) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Sorokina I, Denisenko T, Imreh G, Tyurin Kuzmin P, Kaminskyy V, Gogvadze V, et al. Involvement of autophagy in the outcome of mitotic catastrophe. Sci Rep. 2017;7:14571 pubmed publisher
  3. Kemp V, Dautzenberg I, Limpens R, van den Wollenberg D, Hoeben R. Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. Viruses. 2017;9: pubmed publisher
  4. Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher
  5. Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed publisher
  6. Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  7. Ma K, Fu W, Tang M, Zhang C, Hou T, Li R, et al. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13:579-591 pubmed publisher
  8. Yan H, Gao Y, Zhang Y. Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease. Mol Med Rep. 2017;15:180-186 pubmed publisher
  9. Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, et al. Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy. Cell Death Dis. 2016;7:e2330 pubmed publisher
  10. Velázquez R, Shaw D, Caccamo A, Oddo S. Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease. Mol Neurodegener. 2016;11:52 pubmed publisher
  11. Shen P, Chen M, He M, Chen L, Song Y, Xiao P, et al. Inhibition of ER?/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. Oncotarget. 2016;7:48501-48516 pubmed publisher
  12. Xiao L, Shi X, Zhang Y, Zhu Y, Zhu L, Tian W, et al. YAP induces cisplatin resistance through activation of autophagy in human ovarian carcinoma cells. Onco Targets Ther. 2016;9:1105-14 pubmed publisher
  13. Relic B, Charlier E, Deroyer C, Malaise O, Neuville S, Desoroux A, et al. BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget. 2016;7:23370-82 pubmed publisher
  14. Caccamo A, Branca C, Talboom J, Shaw D, Turner D, Ma L, et al. Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease. J Neurosci. 2015;35:14042-56 pubmed publisher
  15. Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  16. Murrow L, Malhotra R, Debnath J. ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat Cell Biol. 2015;17:300-10 pubmed publisher
  17. Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed publisher
  18. Porter K, Hirt J, Stamer W, Liton P. Autophagic dysregulation in glaucomatous trabecular meshwork cells. Biochim Biophys Acta. 2015;1852:379-85 pubmed publisher
  19. Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed publisher
  20. Kang J, Cho H, Lee S. Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion. Cell Physiol Biochem. 2014;33:23-36 pubmed publisher
  21. Huang M, Sivagurunathan S, Ting S, Jansson P, Austin C, Kelly M, et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets. Am J Pathol. 2013;183:745-57 pubmed publisher