This is a Validated Antibody Database (VAD) review about human Annexin I, based on 34 published articles (read how Labome selects the articles), using Annexin I antibody in all methods. It is aimed to help Labome visitors find the most suited Annexin I antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Annexin I synonym: ANX1; LPC1; annexin A1; annexin I (lipocortin I); annexin-1; calpactin II; calpactin-2; chromobindin-9; phospholipase A2 inhibitory protein

Knockout validation
Invitrogen
rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:100; fig 2
  • western blot knockout validation; human; 1:10,000; fig 1
In order to analyze the contribution to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of formyl peptide receptor pathway by annexin A1, Invitrogen Annexin I antibody (Invitrogen, 71-3400) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 2) and in western blot knockout validation on human samples at 1:10,000 (fig 1). Sci Rep (2016) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
  • immunohistochemistry - frozen section; human; loading ...; fig 2g
Invitrogen Annexin I antibody (Invitrogen, PA5-27315) was used in immunohistochemistry - frozen section on mouse samples (fig 2e) and in immunohistochemistry - frozen section on human samples (fig 2g). Cell Stem Cell (2018) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig s3a
In order to examine the role of the proresolving protein annexin A1 in healing after wire injury, Invitrogen Annexin I antibody (Thermo Scientific, 71-3400) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s3a). Arterioscler Thromb Vasc Biol (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Invitrogen Annexin I antibody (Invitrogen, 71-3400) was used in western blot on human samples . Cell Syst (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:10,000; loading ...; fig 2
In order to elucidate the mechanisms by which Annexin A1 governs metastatic behavior in prostate cancer cells exposed to hypoxia, Invitrogen Annexin I antibody (Invitrogen, 71- 3400) was used in western blot on human samples at 1:10,000 (fig 2). Cell Adh Migr (2017) ncbi
rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:100; fig 2
  • western blot knockout validation; human; 1:10,000; fig 1
In order to analyze the contribution to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of formyl peptide receptor pathway by annexin A1, Invitrogen Annexin I antibody (Invitrogen, 71-3400) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 2) and in western blot knockout validation on human samples at 1:10,000 (fig 1). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse
  • western blot; mouse; loading ...; fig 2a
In order to characterize the P2X7R-secretome in M1 and M2 macrophages., Invitrogen Annexin I antibody (Life Technology, 71-3400) was used in immunocytochemistry on mouse samples and in western blot on mouse samples (fig 2a). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2g
In order to study the results of proteomic screening that identified calreticulin as a miR-27a direct target that represses MHC clas 1 cell surface exposure in colorectal cancer, Invitrogen Annexin I antibody (Thermo Fisher, 71-3400) was used in western blot on human samples (fig 2g). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig 3
In order to investigate the impact of PUFAs membrane incorporation on ABCA1-mediated cholesterol efflux, Invitrogen Annexin I antibody (Invitrogen, 71-C3400) was used in western blot on mouse samples at 1:1000 (fig 3) and in western blot on human samples at 1:1000 (fig 3). Biochim Biophys Acta (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:150
In order to identify dysregulated genes in classical galactosaemia, Invitrogen Annexin I antibody (Biosciences, 71-3400) was used in immunocytochemistry on human samples at 1:150. Mol Genet Metab (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
In order to discuss the clinical applications of using microRNA biomarkers in head and neck squamous cell carcinomas, Invitrogen Annexin I antibody (Zymed Laboratories, 713400) was used in western blot on human samples at 1:1000 (fig 6). BMC Cancer (2013) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to determine the functional role of PAX2 in ovarian cancer, Invitrogen Annexin I antibody (invitrogen, 71-3400) was used in western blot on human samples at 1:1000 (fig 4). Int J Mol Sci (2013) ncbi
rabbit polyclonal
In order to describe plasma membrane microdisruptions in macrophages infected with Mycobacterium tuberculosis, Invitrogen Annexin I antibody (Zymed Laboratories, 71-3400) was used . Nat Immunol (2009) ncbi
rabbit polyclonal
In order to assess the effect of anti-allergic drugs on the trafficking and release of glucocorticoid-induced Annexin-A1 production, Invitrogen Annexin I antibody (Zymed, 71-3400) was used . Biochem Pharmacol (2009) ncbi
rabbit polyclonal
In order to compare expression profiles of intestinal polyps derived humans and mice, Invitrogen Annexin I antibody (Zymed, 71-3400) was used . Am J Pathol (2008) ncbi
rabbit polyclonal
In order to study phagocytosis of Anx-A1 knockout macrophages, Invitrogen Annexin I antibody (ZYMED, 71-3400) was used . Br J Pharmacol (2006) ncbi
Abcam
rabbit monoclonal (EPR19342)
  • western blot; human; loading ...; fig 5b, 5k
Abcam Annexin I antibody (Abcam, ab214486) was used in western blot on human samples (fig 5b, 5k). Cell (2019) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
  • western blot; human; 1:1,000
Abcam Annexin I antibody (Abcam, ab33061) was used in immunohistochemistry - paraffin section on human samples at 1:100 and in western blot on human samples at 1:1,000. BMC Cancer (2014) ncbi
rabbit polyclonal
  • western blot; African green monkey
In order to perform a proteomic analysis of host proteins in Rift Valley fever virus virions and to study the particular significance of Hsp90, Abcam Annexin I antibody (Abcam, ab33061) was used in western blot on African green monkey samples . PLoS ONE (2014) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry; human; 1:100
  • western blot; human; 1:400
Proteintech Group Annexin I antibody (ProteinTech Group, 55018-1-AP) was used in immunohistochemistry on human samples at 1:100 and in western blot on human samples at 1:400. Am J Transl Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:100
Proteintech Group Annexin I antibody (ProteinTech Group, 55018-1-AP) was used in immunohistochemistry on human samples at 1:100. Expert Rev Mol Diagn (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (EH17a)
  • immunocytochemistry; human; fig 1
Santa Cruz Biotechnology Annexin I antibody (Santa Cruz Biotechnology, sc-12740) was used in immunocytochemistry on human samples (fig 1). J Proteome Res (2014) ncbi
OriGene
mouse monoclonal (OTI3A8)
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 1c
OriGene Annexin I antibody (OriGene Technologies, TA500967) was used in immunohistochemistry - paraffin section on human samples at 1:75 (fig 1c). Asian Pac J Cancer Prev (2015) ncbi
MilliporeSigma
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 1
MilliporeSigma Annexin I antibody (Sigma, SAB1405457) was used in western blot on human samples at 1:1000 (fig 1). Int J Mol Med (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 6b
Cell Signaling Technology Annexin I antibody (Cell Signaling Technology, 3299) was used in immunoprecipitation on human samples (fig 6b). Front Mol Neurosci (2018) ncbi
BD Biosciences
mouse monoclonal (29/Annexin I)
  • other; human; loading ...; fig 4c
BD Biosciences Annexin I antibody (BD Biosciences, 610066) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (29/Annexin I)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., BD Biosciences Annexin I antibody (BD Biosciences, 610066) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (29/Annexin I)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, BD Biosciences Annexin I antibody (BD Biosciences, 610066) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (29/Annexin I)
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 3a
BD Biosciences Annexin I antibody (BD Biosciences, 29) was used in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 3a). Oncol Rep (2017) ncbi
mouse monoclonal (29/Annexin I)
  • immunoprecipitation; mouse; fig 6
  • western blot; mouse; fig 6
BD Biosciences Annexin I antibody (BD Biosciences, 29) was used in immunoprecipitation on mouse samples (fig 6) and in western blot on mouse samples (fig 6). J Biol Chem (2016) ncbi
mouse monoclonal (29/Annexin I)
In order to characterize human osteosarcoma U2OS cells for genome landscape of SRSF3-regulated splicing events and gene expression, BD Biosciences Annexin I antibody (BD Biosciences, 29) was used . Nucleic Acids Res (2016) ncbi
mouse monoclonal (29/Annexin I)
  • immunohistochemistry - paraffin section; human; 1:2000; fig 3a
BD Biosciences Annexin I antibody (Transduction Laboratories, 29/Annexin I) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 3a). Oncotarget (2016) ncbi
mouse monoclonal (29/Annexin I)
  • western blot; human; 1:10,000; fig 7
BD Biosciences Annexin I antibody (BD Transduction Laboratories, 610066) was used in western blot on human samples at 1:10,000 (fig 7). PLoS Pathog (2015) ncbi
EMD Millipore
mouse monoclonal (6E4/3)
  • western blot; human; 1:2000; fig 4
EMD Millipore Annexin I antibody (Merck KGaA, MAB3773) was used in western blot on human samples at 1:2000 (fig 4). Oncol Lett (2017) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (EH17a)
  • immunohistochemistry - frozen section; mouse
Developmental Studies Hybridoma Bank Annexin I antibody (DSHB, EH17a) was used in immunohistochemistry - frozen section on mouse samples . Proteome Sci (2014) ncbi
Articles Reviewed
  1. Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  2. Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed publisher
  3. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  4. Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher
  5. Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Keeratichamroen S, Ngiwsara L, Paricharttanakul N, et al. Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells. Oncol Lett. 2017;14:4361-4371 pubmed publisher
  6. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  7. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  8. de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed publisher
  9. Han G, Lu K, Huang J, Ye J, Dai S, Ye Y, et al. Effect of Annexin A1 gene on the proliferation and invasion of esophageal squamous cell carcinoma cells and its regulatory mechanisms. Int J Mol Med. 2017;39:357-363 pubmed publisher
  10. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  11. Onozawa H, Saito M, Saito K, Kanke Y, Watanabe Y, Hayase S, et al. Annexin A1 is involved in resistance to 5-FU in colon cancer cells. Oncol Rep. 2017;37:235-240 pubmed publisher
  12. Bizzarro V, Belvedere R, Migliaro V, Romano E, Parente L, Petrella A. Hypoxia regulates ANXA1 expression to support prostate cancer cell invasion and aggressiveness. Cell Adh Migr. 2017;11:247-260 pubmed publisher
  13. Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed publisher
  14. de Torre Minguela C, Barberà Cremades M, Gómez A, Martín Sánchez F, Pelegrín P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep. 2016;6:22586 pubmed publisher
  15. Colangelo T, Polcaro G, Ziccardi P, Pucci B, Muccillo L, Galgani M, et al. Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer. Cell Death Dis. 2016;7:e2120 pubmed publisher
  16. Rossi P, Sterlini B, Castroflorio E, Marte A, Onofri F, Valtorta F, et al. A Novel Topology of Proline-rich Transmembrane Protein 2 (PRRT2): HINTS FOR AN INTRACELLULAR FUNCTION AT THE SYNAPSE. J Biol Chem. 2016;291:6111-23 pubmed publisher
  17. Fournier N, Tardivel S, Benoist J, Vedie B, Rousseau Ralliard D, Nowak M, et al. Eicosapentaenoic acid membrane incorporation impairs ABCA1-dependent cholesterol efflux via a protein kinase A signaling pathway in primary human macrophages. Biochim Biophys Acta. 2016;1861:331-41 pubmed publisher
  18. Ajiro M, Jia R, Yang Y, Zhu J, Zheng Z. A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. Nucleic Acids Res. 2016;44:1854-70 pubmed publisher
  19. De Marchi T, Timmermans A, Smid M, Look M, Stingl C, Opdam M, et al. Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer. Oncotarget. 2016;7:3098-110 pubmed publisher
  20. Liu Q, Shi M, Bai J, Zheng J. Identification of ANXA1 as a lymphatic metastasis and poor prognostic factor in pancreatic ductal adenocarcinoma. Asian Pac J Cancer Prev. 2015;16:2719-24 pubmed
  21. Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sultmann H, et al. Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog. 2015;11:e1004712 pubmed publisher
  22. Rong B, Zhao C, Liu H, Ming Z, Cai X, Gao W, et al. Elevated serum annexin A1 as potential diagnostic marker for lung cancer: a retrospective case-control study. Am J Transl Res. 2014;6:558-69 pubmed
  23. Biaoxue R, Shuanying Y, Wei L, Zongjuan M, Xiguang C, Qiuhong Z. Co-overexpression of Hsp90-β and annexin A1 with a significantly positive correlation contributes to the diagnosis of lung cancer. Expert Rev Mol Diagn. 2014;14:1067-79 pubmed publisher
  24. Coss K, Treacy E, Cotter E, Knerr I, Murray D, Shin Y, et al. Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?. Mol Genet Metab. 2014;113:177-87 pubmed publisher
  25. Can T, Faas L, Ashford D, Dowle A, Thomas J, O Toole P, et al. Proteomic analysis of laser capture microscopy purified myotendinous junction regions from muscle sections. Proteome Sci. 2014;12:25 pubmed publisher
  26. Gao Y, Chen Y, Xu D, Wang J, Yu G. Differential expression of ANXA1 in benign human gastrointestinal tissues and cancers. BMC Cancer. 2014;14:520 pubmed publisher
  27. Nuss J, Kehn Hall K, Benedict A, Costantino J, Ward M, Peyser B, et al. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors. PLoS ONE. 2014;9:e93483 pubmed publisher
  28. Cypryk W, Ohman T, Eskelinen E, Matikainen S, Nyman T. Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon ?-glucan stimulation. J Proteome Res. 2014;13:2468-77 pubmed publisher
  29. Severino P, Bruggemann H, Andreghetto F, Camps C, Klingbeil M, de Pereira W, et al. MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation. BMC Cancer. 2013;13:533 pubmed publisher
  30. Song H, Kwan S, Izaguirre D, Zu Z, Tsang Y, Tung C, et al. PAX2 Expression in Ovarian Cancer. Int J Mol Sci. 2013;14:6090-105 pubmed publisher
  31. Divangahi M, Chen M, Gan H, Desjardins D, Hickman T, Lee D, et al. Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nat Immunol. 2009;10:899-906 pubmed publisher
  32. Yazid S, Solito E, Christian H, McArthur S, Goulding N, Flower R. Cromoglycate drugs suppress eicosanoid generation in U937 cells by promoting the release of Anx-A1. Biochem Pharmacol. 2009;77:1814-26 pubmed publisher
  33. Gaspar C, Cardoso J, Franken P, Molenaar L, Morreau H, Möslein G, et al. Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis. Am J Pathol. 2008;172:1363-80 pubmed publisher
  34. Yona S, Heinsbroek S, Peiser L, Gordon S, Perretti M, Flower R. Impaired phagocytic mechanism in annexin 1 null macrophages. Br J Pharmacol. 2006;148:469-77 pubmed