This is a Validated Antibody Database (VAD) review about human AXIN2, based on 23 published articles (read how Labome selects the articles), using AXIN2 antibody in all methods. It is aimed to help Labome visitors find the most suited AXIN2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
AXIN2 synonym: AXIL; ODCRCS

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (76G6)
  • western blot knockout validation; human; 1:500; fig 3-s1
In order to investigate regulatory mechanisms in canonical WNT signaling, Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot knockout validation on human samples at 1:500 (fig 3-s1). elife (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR2005(2))
  • immunohistochemistry; mouse; loading ...; fig 1g
Abcam AXIN2 antibody (Abcam, ab109307) was used in immunohistochemistry on mouse samples (fig 1g). Cell Rep (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5i
  • flow cytometry; human; 1:50; loading ...; fig 5f, 5g
Abcam AXIN2 antibody (Abcam, ab32197) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 5i) and in flow cytometry on human samples at 1:50 (fig 5f, 5g). Am J Cancer Res (2020) ncbi
domestic rabbit monoclonal (EPR2005(2))
  • western blot; human; loading ...; fig 6h
Abcam AXIN2 antibody (Abcam, ab109307) was used in western blot on human samples (fig 6h). Cancer Res (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 3i
Abcam AXIN2 antibody (Abcam, ab32197) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 3i). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR2005(2))
  • western blot; mouse; 1:2000; fig 3c
Abcam AXIN2 antibody (abcam, ab109307) was used in western blot on mouse samples at 1:2000 (fig 3c). Int J Mol Sci (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig s1f
Invitrogen AXIN2 antibody (Invitrogen, PA5-25331) was used in immunohistochemistry on mouse samples at 1:100 (fig s1f). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6i
Invitrogen AXIN2 antibody (Invitrogen, PA5-78247) was used in western blot on mouse samples (fig 6i). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (J.415.10)
  • western blot; human; 1:133
In order to determine the prognostic role of the Wnt-signaling antagonist SFRP1 in bladder cancer, Invitrogen AXIN2 antibody (BioMol/Thermo Fisher Scientific, MA5-15015) was used in western blot on human samples at 1:133. J Cancer Res Clin Oncol (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (76G6)
  • western blot; human; 1:2000; loading ...; fig s3c
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on human samples at 1:2000 (fig s3c). iScience (2022) ncbi
domestic rabbit monoclonal (76G6)
  • immunohistochemistry - paraffin section; human; fig 7i
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in immunohistochemistry - paraffin section on human samples (fig 7i) and in western blot on human samples (fig 3d). Sci Adv (2022) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; loading ...; fig 6d
Cell Signaling Technology AXIN2 antibody (CST, 2151) was used in western blot on human samples (fig 6d). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on human samples (fig 3d). iScience (2021) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 76G6) was used in western blot on human samples (fig 1b). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology AXIN2 antibody (Cell Signaling Technology, 2151) was used in western blot on human samples at 1:1000. Nat Commun (2019) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology AXIN2 antibody (CST, 2151) was used in western blot on human samples (fig 3d). Cell Commun Signal (2019) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on mouse samples (fig 5b). J Cell Mol Med (2019) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; loading ...; fig s12f
Cell Signaling Technology AXIN2 antibody (Cell Signaling, #2151) was used in western blot on human samples (fig s12f). Proc Natl Acad Sci U S A (2018) ncbi
domestic rabbit monoclonal (76G6)
  • western blot knockout validation; human; 1:500; fig 3-s1
In order to investigate regulatory mechanisms in canonical WNT signaling, Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot knockout validation on human samples at 1:500 (fig 3-s1). elife (2016) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; fig 1
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; fig 1e
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on human samples (fig 1e). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; fig 5
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 2151) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi
domestic rabbit monoclonal (76G6)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology AXIN2 antibody (Cell signaling, 2151) was used in western blot on human samples at 1:1000 (fig 2). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D48G4)
  • western blot; human
Cell Signaling Technology AXIN2 antibody (Cell Signaling, 5863) was used in western blot on human samples . Mol Med Rep (2015) ncbi
Articles Reviewed
  1. Pan R, Yu Y, Zhu H, Zhang W, Qin Y, Ye L, et al. RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation. iScience. 2022;25:105184 pubmed publisher
  2. Tanton H, Sewastianik T, Seo H, Remillard D, Pierre R, Bala P, et al. A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. Sci Adv. 2022;8:eabm3108 pubmed publisher
  3. Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, et al. Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Cell Death Dis. 2021;12:912 pubmed publisher
  4. Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher
  5. Ryu H, Nam K, Kim H, Song J, Hwang S, Kim J, et al. Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor. Int J Mol Sci. 2021;22: pubmed publisher
  6. Teufel S, Köckemann P, Fabritius C, Wolff L, Bertrand J, Pap T, et al. Loss of the WNT9a ligand aggravates the rheumatoid arthritis-like symptoms in hTNF transgenic mice. Cell Death Dis. 2021;12:494 pubmed publisher
  7. Meyers C, Lee S, Sono T, Xu J, Negri S, Tian Y, et al. A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone. Cell Rep. 2020;31:107696 pubmed publisher
  8. Huang Y, Huang J, Huang Y, Gan L, Long L, Pu A, et al. TFRC promotes epithelial ovarian cancer cell proliferation and metastasis via up-regulation of AXIN2 expression. Am J Cancer Res. 2020;10:131-147 pubmed
  9. Cui J, Duan J, Chu J, Guo C, Xi M, Li Y, et al. Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway. Aging (Albany NY). 2020;12:1591-1609 pubmed publisher
  10. Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, et al. GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling. Nat Commun. 2019;10:3882 pubmed publisher
  11. Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
  12. Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed publisher
  13. Yang F, Fang E, Mei H, Chen Y, Li H, Li D, et al. Cis-Acting circ-CTNNB1 Promotes β-Catenin Signaling and Cancer Progression via DDX3-Mediated Transactivation of YY1. Cancer Res. 2019;79:557-571 pubmed publisher
  14. Harper C, Woodcock D, Lam C, Garcia Albornoz M, Adamson A, Ashall L, et al. Temperature regulates NF-κB dynamics and function through timing of A20 transcription. Proc Natl Acad Sci U S A. 2018;115:E5243-E5249 pubmed publisher
  15. Lebensohn A, Dubey R, Neitzel L, Tacchelly Benites O, Yang E, Marceau C, et al. Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. elife. 2016;5: pubmed publisher
  16. Haraguchi R, Kitazawa R, Mori K, Tachibana R, Kiyonari H, Imai Y, et al. sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss. Sci Rep. 2016;6:25198 pubmed publisher
  17. Li N, Liu S, Zhang H, Deng Z, Zhao H, Zhao Q, et al. Exogenous R-Spondin1 Induces Precocious Telogen-to-Anagen Transition in Mouse Hair Follicles. Int J Mol Sci. 2016;17: pubmed publisher
  18. Li Y, Lu W, Saini S, Moukha Chafiq O, Pathak V, Ananthan S. Identification of quinazoline compounds as novel potent inhibitors of Wnt/?-catenin signaling in colorectal cancer cells. Oncotarget. 2016;7:11263-70 pubmed publisher
  19. Shi J, Liu Y, Xu X, Zhang W, Yu T, Jia J, et al. Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling. Mol Cell Biol. 2015;35:3301-11 pubmed publisher
  20. Cheng Y, Phoon Y, Jin X, Chong S, Ip J, Wong B, et al. Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. Oncotarget. 2015;6:14428-39 pubmed
  21. Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed publisher
  22. Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, et al. Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nat Commun. 2015;6:6156 pubmed publisher
  23. Yu J, Kong C, Zhang Z, Zhan B, Jiang Z. Aplasia Ras homolog member I expression induces apoptosis in renal cancer cells via the β-catenin signaling pathway. Mol Med Rep. 2015;11:475-81 pubmed publisher