This is a Validated Antibody Database (VAD) review about human ASCL2, based on 3 published articles (read how Labome selects the articles), using ASCL2 antibody in all methods. It is aimed to help Labome visitors find the most suited ASCL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ASCL2 synonym: ASH2; HASH2; MASH2; bHLHa45; achaete-scute homolog 2; ASH-2; achaete-scute complex homolog 2; achaete-scute complex-like 2; class A basic helix-loop-helix protein 45; mammalian achaete/scute homologue 2

Knockout validation
EMD Millipore
mouse monoclonal (7E2)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 1d
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
EMD Millipore ASCL2 antibody (Millipore, MAB4418) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 1d) and in western blot knockout validation on mouse samples at 1:1000 (fig 2a). Development (2017) ncbi
EMD Millipore
mouse monoclonal (8F1)
  • immunohistochemistry; mouse; fig 2a
In order to investigate the involvement of achaete-scute complex homologue 2 in the pathogenesis of Sjogren's syndrome-like disease in the NOD/ShiLtJ mouse, EMD Millipore ASCL2 antibody (Millipore, 8F1) was used in immunohistochemistry on mouse samples (fig 2a). Immunol Lett (2017) ncbi
mouse monoclonal (7E2)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 1d
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
EMD Millipore ASCL2 antibody (Millipore, MAB4418) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 1d) and in western blot knockout validation on mouse samples at 1:1000 (fig 2a). Development (2017) ncbi
mouse monoclonal (7E2)
  • chromatin immunoprecipitation; human; fig 4
  • western blot; human; 1:350; fig 6
EMD Millipore ASCL2 antibody (Millipore, mab4418) was used in chromatin immunoprecipitation on human samples (fig 4) and in western blot on human samples at 1:350 (fig 6). Oncotarget (2015) ncbi
Articles Reviewed
  1. Kim S, Kwon J, Park J, Seo H, Jung K, Moon Y, et al. Achaete-scute complex homologue 2 accelerates the development of Sjögren's syndrome-like disease in the NOD/ShiLtJ mouse. Immunol Lett. 2017;190:26-33 pubmed publisher
  2. Wang C, Wang M, Arrington J, Shan T, Yue F, Nie Y, et al. Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors. Development. 2017;144:235-247 pubmed publisher
  3. Shang Y, Pan Q, Chen L, Ye J, Zhong X, Li X, et al. Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation. Oncotarget. 2015;6:30993-1006 pubmed publisher