This is a Validated Antibody Database (VAD) review about human ASAH1, based on 5 published articles (read how Labome selects the articles), using ASAH1 antibody in all methods. It is aimed to help Labome visitors find the most suited ASAH1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ASAH1 synonym: AC; ACDase; ASAH; PHP; PHP32; SMAPME

Santa Cruz Biotechnology
mouse monoclonal (23)
  • western blot; human; fig 1e
Santa Cruz Biotechnology ASAH1 antibody (Santa Cruz Biotechnology, sc-136275) was used in western blot on human samples (fig 1e). Aging (Albany NY) (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1d
MilliporeSigma ASAH1 antibody (Sigma-Aldrich, HPA005468) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1d). Mol Metab (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:125; loading ...; fig 2b
MilliporeSigma ASAH1 antibody (Sigma, HPA005468) was used in western blot on mouse samples at 1:125 (fig 2b). Nat Neurosci (2019) ncbi
BD Biosciences
mouse monoclonal (23/Acid Ceramidase)
  • western blot; human; 1:1000; fig 2
BD Biosciences ASAH1 antibody (BD Biosciences, 612302) was used in western blot on human samples at 1:1000 (fig 2). Oncotarget (2016) ncbi
mouse monoclonal (23/Acid Ceramidase)
  • western blot; mouse
  • western blot; human
In order to study the role of the sphingosine-1-phosphate in the mechanism by which acid ceramidase promotes oncogenic Akt signaling, BD Biosciences ASAH1 antibody (BD Transduction, 612302) was used in western blot on mouse samples and in western blot on human samples . Oncogenesis (2013) ncbi
Articles Reviewed
  1. Munk R, Anerillas C, Rossi M, Tsitsipatis D, Martindale J, Herman A, et al. Acid ceramidase promotes senescent cell survival. Aging (Albany NY). 2021;13:15750-15769 pubmed publisher
  2. Malvi P, Janostiak R, Nagarajan A, Zhang X, Wajapeyee N. N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production. Mol Metab. 2021;48:101217 pubmed publisher
  3. Laferrière F, Maniecka Z, Pérez Berlanga M, Hruska Plochan M, Gilhespy L, Hock E, et al. TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates. Nat Neurosci. 2019;22:65-77 pubmed publisher
  4. Stefanovic M, Tutusaus A, Martinez Nieto G, Bárcena C, de Gregorio E, Moutinho C, et al. Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. Oncotarget. 2016;7:8253-67 pubmed publisher
  5. Beckham T, Cheng J, Lu P, Shao Y, Troyer D, Lance R, et al. Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. Oncogenesis. 2013;2:e49 pubmed publisher