This is a Validated Antibody Database (VAD) review about human ARNTL, based on 17 published articles (read how Labome selects the articles), using ARNTL antibody in all methods. It is aimed to help Labome visitors find the most suited ARNTL antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ARNTL synonym: BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC; bHLHe5

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • western blot knockout validation; mouse; loading ...; fig 4a
Santa Cruz Biotechnology ARNTL antibody (Santa Cruz Biotechnology, clone B-1) was used in western blot knockout validation on mouse samples (fig 4a). elife (2020) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; rat; loading ...; fig 3c
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 1b
In order to show decreased Bmal1 in GLAST-positive astrocytes alters circadian locomotor behavior and cognition in mice, Abcam ARNTL antibody (Abcam, ab93806) was used in western blot knockout validation on rat samples (fig 3c) and in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 1b). Nat Commun (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • western blot knockout validation; mouse; loading ...; fig 4a
Santa Cruz Biotechnology ARNTL antibody (Santa Cruz Biotechnology, clone B-1) was used in western blot knockout validation on mouse samples (fig 4a). elife (2020) ncbi
mouse monoclonal (B-1)
  • western blot; rat; fig 5a
Santa Cruz Biotechnology ARNTL antibody (Santa, sc-365645) was used in western blot on rat samples (fig 5a). Cell (2019) ncbi
mouse monoclonal (A-6)
  • western blot; human; loading ...; fig 1c
  • immunohistochemistry; rat; 1:100; loading ...; fig 2g
Santa Cruz Biotechnology ARNTL antibody (SantaCruz, sc-373955) was used in western blot on human samples (fig 1c) and in immunohistochemistry on rat samples at 1:100 (fig 2g). PLoS ONE (2018) ncbi
mouse monoclonal (B-1)
  • western blot; human; fig s8
Santa Cruz Biotechnology ARNTL antibody (Santa Cruz, sc-365645) was used in western blot on human samples (fig s8). Nat Struct Mol Biol (2015) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1j
Abcam ARNTL antibody (Abcam, ab93806) was used in western blot on mouse samples (fig 1j). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1f
Abcam ARNTL antibody (Abcam, ab93806) was used in western blot on mouse samples (fig 1f). Cell (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig 3a
  • western blot; human; loading ...; fig 4a
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1c
Abcam ARNTL antibody (Abcam, ab93806) was used in immunohistochemistry on human samples at 1:1000 (fig 3a), in western blot on human samples (fig 4a) and in immunohistochemistry on mouse samples at 1:1000 (fig 1c). Histochem Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; rat; loading ...; fig 3c
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 1b
In order to show decreased Bmal1 in GLAST-positive astrocytes alters circadian locomotor behavior and cognition in mice, Abcam ARNTL antibody (Abcam, ab93806) was used in western blot knockout validation on rat samples (fig 3c) and in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 1b). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • ChIP-Seq; human; fig 2
Abcam ARNTL antibody (Abcam, ab3350) was used in ChIP-Seq on human samples (fig 2). Biochem Biophys Res Commun (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2a
Invitrogen ARNTL antibody (Affinity BioReagents, PA1-523) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2a). J Pineal Res (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1c
  • immunohistochemistry; human; loading ...; fig 1b
In order to study circadian rhythmicity in cultured chondrocytes and determine the role of NR1D1 and BMAL1 in regulating chondrocyte functions, Invitrogen ARNTL antibody (Thermo Scientific, PA1-523) was used in immunohistochemistry on mouse samples (fig 1c) and in immunohistochemistry on human samples (fig 1b). Osteoarthritis Cartilage (2017) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2b
MilliporeSigma ARNTL antibody (Sigma, SAB4300614) was used in western blot on mouse samples at 1:1000 (fig 2b). elife (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2L7G)
  • immunoprecipitation; human; loading ...; fig 2f
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology ARNTL antibody (Cell Signaling, 14020) was used in immunoprecipitation on human samples (fig 2f) and in western blot on human samples (fig 1b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D2L7G)
  • western blot; mouse; 1:1000; loading ...; fig 2c
Cell Signaling Technology ARNTL antibody (Cell Signaling Technology, 14020S) was used in western blot on mouse samples at 1:1000 (fig 2c). Cell Death Dis (2018) ncbi
domestic rabbit monoclonal (D2L7G)
  • western blot; mouse; loading ...; fig 2d
Cell Signaling Technology ARNTL antibody (Cell Signaling, 14020) was used in western blot on mouse samples (fig 2d). Mol Neurobiol (2018) ncbi
domestic rabbit monoclonal (D2L7G)
  • western blot; human; 1:1000; loading ...; fig 1b
In order to demonstrate that MYC persistently upregulates REV-ERBalpha, Cell Signaling Technology ARNTL antibody (Cell Signaling, 14020S) was used in western blot on human samples at 1:1000 (fig 1b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D2L7G)
  • western blot; rat; loading ...; fig 1b
Cell Signaling Technology ARNTL antibody (Cell Signaling, 14020) was used in western blot on rat samples (fig 1b). Oncotarget (2016) ncbi
Articles Reviewed
  1. Alexander R, Liou Y, Knudsen N, Starost K, Xu C, Hyde A, et al. Bmal1 integrates mitochondrial metabolism and macrophage activation. elife. 2020;9: pubmed publisher
  2. Brigidi G, Hayes M, Delos Santos N, Hartzell A, Texari L, Lin P, et al. Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers. Cell. 2019;179:373-391.e27 pubmed publisher
  3. Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed publisher
  4. Koronowski K, Kinouchi K, Welz P, Smith J, Zinna V, Shi J, et al. Defining the Independence of the Liver Circadian Clock. Cell. 2019;177:1448-1462.e14 pubmed publisher
  5. Welz P, Zinna V, Symeonidi A, Koronowski K, Kinouchi K, Smith J, et al. BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell. 2019;177:1436-1447.e12 pubmed publisher
  6. Hodge B, Zhang X, Gutierrez Monreal M, Cao Y, Hammers D, Yao Z, et al. MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle. elife. 2019;8: pubmed publisher
  7. Jilg A, Bechstein P, Saade A, Dick M, Li T, Tosini G, et al. Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res. 2019;66:e12553 pubmed publisher
  8. Rivera Reyes A, Ye S, E Marino G, Egolf S, E Ciotti G, Chor S, et al. YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma. Cell Death Dis. 2018;9:1108 pubmed publisher
  9. Kim H, Kim H, Kim J, Kim T, Lee S. Asymmetric expression level of clock genes in left vs. right nasal mucosa in humans with and without allergies and in rats: Circadian characteristics and possible contribution to nasal cycle. PLoS ONE. 2018;13:e0194018 pubmed publisher
  10. Sato F, Kohsaka A, Takahashi K, Otao S, Kitada Y, Iwasaki Y, et al. Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-?. Histochem Cell Biol. 2017;148:617-624 pubmed publisher
  11. Beker M, Çağlayan B, Yalcin E, Caglayan A, Turkseven S, Gurel B, et al. Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT. Mol Neurobiol. 2018;55:2565-2576 pubmed publisher
  12. Altman B, Hsieh A, Gouw A, Dang C. Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERB?. Nat Commun. 2017;8:14862 pubmed publisher
  13. Barca Mayo O, Pons Espinal M, Follert P, Armirotti A, Berdondini L, De Pietri Tonelli D. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun. 2017;8:14336 pubmed publisher
  14. Akagi R, Akatsu Y, Fisch K, Alvarez Garcia O, Teramura T, Muramatsu Y, et al. Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-? signaling in chondrocytes. Osteoarthritis Cartilage. 2017;25:943-951 pubmed publisher
  15. Xiong W, Li J, Zhang E, Huang H. BMAL1 regulates transcription initiation and activates circadian clock gene expression in mammals. Biochem Biophys Res Commun. 2016;473:1019-1025 pubmed publisher
  16. Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and ROR? control HIF-1? transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed publisher
  17. Xu H, Gustafson C, Sammons P, Khan S, Parsley N, Ramanathan C, et al. Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus. Nat Struct Mol Biol. 2015;22:476-484 pubmed publisher