This is a Validated Antibody Database (VAD) review about human ARHGEF1, based on 6 published articles (read how Labome selects the articles), using ARHGEF1 antibody in all methods. It is aimed to help Labome visitors find the most suited ARHGEF1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ARHGEF1 synonym: GEF1; IMD62; LBCL2; LSC; P115-RHOGEF; SUB1.5

Santa Cruz Biotechnology
mouse monoclonal (C-9)
  • western blot; human; 1:1000; loading ...; fig 5a
Santa Cruz Biotechnology ARHGEF1 antibody (Santa Cruz, sc-74565) was used in western blot on human samples at 1:1000 (fig 5a). Cancer Sci (2021) ncbi
mouse monoclonal (D-11)
  • western blot; human; loading ...; fig s5a
Santa Cruz Biotechnology ARHGEF1 antibody (Santa Cruz, sc-166341) was used in western blot on human samples (fig s5a). J Cell Biol (2019) ncbi
mouse monoclonal (E-4)
  • western blot; human; loading ...; fig 3f
Santa Cruz Biotechnology ARHGEF1 antibody (Santa Cruz Biotechnology Inc, sc-166301) was used in western blot on human samples (fig 3f). J Clin Invest (2019) ncbi
mouse monoclonal (E-4)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology ARHGEF1 antibody (Santa Cruz Biotechnology, sc-166301) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D25D2)
  • western blot; human; fig 4
Cell Signaling Technology ARHGEF1 antibody (Cell Signaling, 3669) was used in western blot on human samples (fig 4). Mol Biol Cell (2016) ncbi
domestic rabbit monoclonal (D25D2)
  • western blot; human; 1:1000; fig s6
Cell Signaling Technology ARHGEF1 antibody (Cell Signaling, 3669) was used in western blot on human samples at 1:1000 (fig s6). Nat Commun (2016) ncbi
Articles Reviewed
  1. Murakami T, Takasawa A, Takasawa K, Akimoto T, Aoyama T, Magara K, et al. Aberrant expression of junctional adhesion molecule-A contributes to the malignancy of cervical adenocarcinoma by interaction with poliovirus receptor/CD155. Cancer Sci. 2021;112:906-917 pubmed publisher
  2. Juettner V, Kruse K, Dan A, Vu V, Khan Y, Le J, et al. VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism. J Cell Biol. 2019;218:1725-1742 pubmed publisher
  3. Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019;129:1047-1060 pubmed publisher
  4. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  5. Scott D, Tolbert C, Burridge K. Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF. Mol Biol Cell. 2016;27:1420-30 pubmed publisher
  6. Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher