This is a Validated Antibody Database (VAD) review about human APC, based on 24 published articles (read how Labome selects the articles), using APC antibody in all methods. It is aimed to help Labome visitors find the most suited APC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
APC synonym: BTPS2; DP2; DP2.5; DP3; GS; PPP1R46

Abcam
domestic rabbit monoclonal (EP701Y)
  • western blot; mouse; 1:1000; loading ...; fig 3l
Abcam APC antibody (Abcam, ab40778) was used in western blot on mouse samples at 1:1000 (fig 3l). Aging (Albany NY) (2020) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 8f
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 8f). elife (2019) ncbi
domestic rabbit monoclonal (EP701Y)
  • western blot; human; 1:1000; loading ...; fig 3d
Abcam APC antibody (Abcam, ab40778) was used in western blot on human samples at 1:1000 (fig 3d). Aging (Albany NY) (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:2000; loading ...; fig 2b
Abcam APC antibody (Abcam, ab15270) was used in western blot on rat samples at 1:2000 (fig 2b). Biosci Rep (2019) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry; rat; 1:50; loading ...; fig s1c
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry on rat samples at 1:50 (fig s1c). Cell Death Differ (2018) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry; rat; 1:100; loading ...; fig 5
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry on rat samples at 1:100 (fig 5). J Histochem Cytochem (2018) ncbi
mouse monoclonal (CC-1)
  • immunocytochemistry; mouse; 1:200; loading ...; fig 3e
Abcam APC antibody (Abcam, ab16794) was used in immunocytochemistry on mouse samples at 1:200 (fig 3e). Stem Cell Reports (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig 4c
Abcam APC antibody (Abcam, ab154906) was used in western blot on human samples at 1:500 (fig 4c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EP701Y)
  • immunohistochemistry; human; 1:100; fig 4
Abcam APC antibody (Abcam, Ab40778) was used in immunohistochemistry on human samples at 1:100 (fig 4). J Clin Endocrinol Metab (2016) ncbi
mouse monoclonal (CC-1)
  • immunocytochemistry; human; 1:300; loading ...; fig 2a
  • western blot; human; 1:1000; loading ...; fig 2b
  • immunohistochemistry; mouse; 1:300; loading ...; fig 3a
  • immunoprecipitation; rat; loading ...; fig 1b
  • western blot; rat; 1:1000; loading ...; fig 1b
In order to demonstrate that the CC1 antibody binds Quaking 7 in myelinating oligodendrocytes, Abcam APC antibody (AbCam, 16794) was used in immunocytochemistry on human samples at 1:300 (fig 2a), in western blot on human samples at 1:1000 (fig 2b), in immunohistochemistry on mouse samples at 1:300 (fig 3a), in immunoprecipitation on rat samples (fig 1b) and in western blot on rat samples at 1:1000 (fig 1b). J Neurochem (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - free floating section; rat; 1:100; fig 5
Abcam APC antibody (Abcam, Ab16794) was used in immunohistochemistry - free floating section on rat samples at 1:100 (fig 5). Brain (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3a
In order to investigate the link between chronic stress and NG2 positive cell maturation and myelination, Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 3a). Exp Neurol (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1). Stem Cell Reports (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - paraffin section; rat; 1:1000
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - paraffin section on rat samples at 1:1000. Cell Death Dis (2015) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2
In order to analyze the process of neuronal cell death after traumatic brain injury due to impaired autophagy flux, Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2). Autophagy (2014) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - paraffin section; mouse
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - paraffin section on mouse samples . J Neurosci (2014) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:20
In order to use a SIP1-EGFP reporter mouse to study brain development, Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:20. Genesis (2014) ncbi
mouse monoclonal (ALi 12-28)
  • immunocytochemistry; dogs; 1:200
In order to study the role of Kif3a in microtubular dynamics, migration and lumen formation of MDCK cells, Abcam APC antibody (Abcam, AB58) was used in immunocytochemistry on dogs samples at 1:200. PLoS ONE (2013) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; rat; 1:400
Abcam APC antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on rat samples at 1:400. J Comp Neurol (2008) ncbi
Santa Cruz Biotechnology
mouse monoclonal (ALi 12-28)
  • western blot; human; 1:1000; loading ...; fig 4b
Santa Cruz Biotechnology APC antibody (Santa, sc-53165) was used in western blot on human samples at 1:1000 (fig 4b). BMC Gastroenterol (2019) ncbi
mouse monoclonal
  • western blot; human; fig 1d
In order to investigate the role of growth hormone in colon cancer, Santa Cruz Biotechnology APC antibody (Santa Cruz, sc-393704) was used in western blot on human samples (fig 1d). Proc Natl Acad Sci U S A (2016) ncbi
MilliporeSigma
mouse monoclonal (CC-1)
  • immunohistochemistry; mouse; 1:300; loading ...; fig 1a
MilliporeSigma APC antibody (Millipor, MABC200) was used in immunohistochemistry on mouse samples at 1:300 (fig 1a). Nature (2019) ncbi
Novus Biologicals
domestic rabbit polyclonal (3E2B)
  • western blot; mouse; 1:1000; loading ...; fig s7d
Novus Biologicals APC antibody (Novus, NBP2-15422) was used in western blot on mouse samples at 1:1000 (fig s7d). Nat Commun (2019) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunoprecipitation; human; 1:100; loading ...; fig 4h, 5a, 5b
Cell Signaling Technology APC antibody (Cell Signaling, 2504S) was used in immunoprecipitation on human samples at 1:100 (fig 4h, 5a, 5b). Mol Cell (2018) ncbi
Articles Reviewed
  1. Cai L, Chao G, Li W, Zhu J, Li F, Qi B, et al. Activated CD4+ T cells-derived exosomal miR-142-3p boosts post-ischemic ventricular remodeling by activating myofibroblast. Aging (Albany NY). 2020;12:7380-7396 pubmed publisher
  2. Liu Q, Zhou C, Zhang B. Upregulation of musashi1 increases malignancy of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway and predicts a poor prognosis. BMC Gastroenterol. 2019;19:230 pubmed publisher
  3. Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed publisher
  4. Stedehouder J, Brizee D, Slotman J, Pascual Garcia M, Leyrer M, Bouwen B, et al. Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex. elife. 2019;8: pubmed publisher
  5. Hu Y, Zhao Y, Shi C, Ren P, Wei B, Guo Y, et al. A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888. Aging (Albany NY). 2019;11:8068-8084 pubmed publisher
  6. SEGEL M, Neumann B, Hill M, Weber I, Viscomi C, Zhao C, et al. Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature. 2019;573:130-134 pubmed publisher
  7. Lai X, Deng Z, Zhu X, Chen Z. Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-κB signaling pathway mediated inflammatory response. Biosci Rep. 2019;39: pubmed publisher
  8. Ji L, Lu B, Wang Z, Yang Z, Reece Hoyes J, Russ C, et al. Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction. Mol Cell. 2018;72:37-47.e4 pubmed publisher
  9. Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  10. Wang Y, Lin Y, Wu Y, Yao Z, Tang J, Shen L, et al. Expression and Cellular Localization of IFITM1 in Normal and Injured Rat Spinal Cords. J Histochem Cytochem. 2018;66:175-187 pubmed publisher
  11. Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, et al. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. Stem Cell Reports. 2017;8:673-684 pubmed publisher
  12. Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher
  13. Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al. Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed
  14. Bin J, Harris S, Kennedy T. The oligodendrocyte-specific antibody 'CC1' binds Quaking 7. J Neurochem. 2016;139:181-186 pubmed publisher
  15. Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
  16. Delbary Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, et al. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. Brain. 2016;139:1762-82 pubmed publisher
  17. Yang Y, Zhang Y, Luo F, Li B. Chronic stress regulates NG2⁺ cell maturation and myelination in the prefrontal cortex through induction of death receptor 6. Exp Neurol. 2016;277:202-214 pubmed publisher
  18. Kawabata S, Takano M, Numasawa Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. 2016;6:1-8 pubmed publisher
  19. Liu S, Sarkar C, Dinizo M, Faden A, Koh E, Lipinski M, et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015;6:e1582 pubmed publisher
  20. Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden A, Lipinski M. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 2014;10:2208-22 pubmed publisher
  21. Bull S, Bin J, Beaumont E, Boutet A, Krimpenfort P, Sadikot A, et al. Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes. J Neurosci. 2014;34:9768-78 pubmed publisher
  22. Nishizaki Y, Takagi T, Matsui F, Higashi Y. SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014;52:56-67 pubmed publisher
  23. Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed publisher
  24. Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed publisher