This is a Validated Antibody Database (VAD) review about human AIRE, based on 4 published articles (read how Labome selects the articles), using AIRE antibody in all methods. It is aimed to help Labome visitors find the most suited AIRE antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
AIRE synonym: AIRE1; APECED; APS1; APSI; PGA1; autoimmune regulator; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein

Abcam
goat polyclonal
  • immunohistochemistry; human; loading ...; fig 9a
In order to explore the contribution of epithelial cells to systemic sclerosis pathogenesis, Abcam AIRE antibody (Abcam, ab13573) was used in immunohistochemistry on human samples (fig 9a). J Exp Med (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
In order to investigate the phosphorylation and ubiquitylation of autoimmune regulator, Abcam AIRE antibody (Abcam, ab78211) was used in western blot on human samples (fig 3a). J Biol Chem (2016) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; human
Abcam AIRE antibody (Abcam, ab78065) was used in immunohistochemistry - paraffin section on human samples . J Immunol (2014) ncbi
Invitrogen
rat monoclonal (TM-724)
  • immunohistochemistry - frozen section; human; fig s2
In order to investigate the role of FAT10 in thymic antigen presentation, Invitrogen AIRE antibody (eBioscience, TM-724) was used in immunohistochemistry - frozen section on human samples (fig s2). J Immunol (2015) ncbi
Articles Reviewed
  1. Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
  2. Shao W, Zumer K, Fujinaga K, Peterlin B. FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator). J Biol Chem. 2016;291:17953-63 pubmed publisher
  3. Buerger S, Herrmann V, Mundt S, Trautwein N, Groettrup M, Basler M. The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J Immunol. 2015;195:4106-16 pubmed publisher
  4. Skogberg G, Lundberg V, Lindgren S, Gudmundsdottir J, Sandström K, Kämpe O, et al. Altered expression of autoimmune regulator in infant down syndrome thymus, a possible contributor to an autoimmune phenotype. J Immunol. 2014;193:2187-95 pubmed publisher