This is a Validated Antibody Database (VAD) review about human AGER, based on 25 published articles (read how Labome selects the articles), using AGER antibody in all methods. It is aimed to help Labome visitors find the most suited AGER antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
AGER synonym: RAGE; SCARJ1

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 5c
Abcam AGER antibody (Abcam, 3611) was used in western blot knockout validation on mouse samples at 1:1000 (fig 5c). Cell Death Dis (2021) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; loading ...; fig s3a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s3d
  • immunohistochemistry - free floating section; mouse; loading ...; fig 3d
Abcam AGER antibody (Abcam, ab3611) was used in immunohistochemistry knockout validation on mouse samples (fig s3a), in western blot knockout validation on mouse samples at 1:1000 (fig s3d) and in immunohistochemistry - free floating section on mouse samples (fig 3d). J Neuroinflammation (2020) ncbi
Abcam
domestic rabbit monoclonal (EPR21171)
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig s3b
Abcam AGER antibody (Abcam, ab216329) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig s3b). Mol Med (2022) ncbi
domestic rabbit monoclonal (EPR21171)
  • western blot; rat; 1:1000; fig 2b
Abcam AGER antibody (Abcam, ab216329) was used in western blot on rat samples at 1:1000 (fig 2b). Mol Med Rep (2021) ncbi
domestic rabbit monoclonal (EPR21171)
  • western blot; mouse; 1:1000; loading ...; fig 5a
Abcam AGER antibody (Abcam, ab216329) was used in western blot on mouse samples at 1:1000 (fig 5a). J Inflamm Res (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 5c
Abcam AGER antibody (Abcam, 3611) was used in western blot knockout validation on mouse samples at 1:1000 (fig 5c). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 3e
Abcam AGER antibody (Abcam, ab3611) was used in western blot on mouse samples at 1:2000 (fig 3e). Mol Med Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; loading ...; fig s3a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s3d
  • immunohistochemistry - free floating section; mouse; loading ...; fig 3d
Abcam AGER antibody (Abcam, ab3611) was used in immunohistochemistry knockout validation on mouse samples (fig s3a), in western blot knockout validation on mouse samples at 1:1000 (fig s3d) and in immunohistochemistry - free floating section on mouse samples (fig 3d). J Neuroinflammation (2020) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 2d
Abcam AGER antibody (Abcam, ab54741) was used in western blot on human samples at 1:1000 (fig 2d). Breast Cancer Res (2017) ncbi
domestic rabbit monoclonal (EPR12206)
  • western blot; rat; loading ...; fig s1a
In order to determine the mechanism by which tiron functions, Abcam AGER antibody (Abcam, ab172473) was used in western blot on rat samples (fig s1a). Clin Exp Pharmacol Physiol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2a
Abcam AGER antibody (Abcam, ab37647) was used in western blot on human samples at 1:1000 (fig 2a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to report that metformin inhibits advanced glycation end product-induced inflammatory response through AMPK activation and RAGE/NFkappaB pathway suppression, Abcam AGER antibody (Abcam, ab3611) was used in western blot on mouse samples at 1:1000 (fig 3a). J Diabetes Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 2
Abcam AGER antibody (Abcam, ab3611) was used in western blot on rat samples (fig 2). Mol Med Rep (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; rat; loading ...; fig 7a
  • western blot; rat; 1:1000; loading ...; fig 6c
In order to investigate the relationship between HMGB1, TLR4, and RAGE in the development and maintenance of chemotherapy-induced painful neuropathy, Abcam AGER antibody (Abcam, ab3611) was used in immunohistochemistry - frozen section on rat samples (fig 7a) and in western blot on rat samples at 1:1000 (fig 6c). Toxicology (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to study the paracrine effects of S100A4 and receptor for advanced glycation end products on melanoma metastasis, Abcam AGER antibody (abcam, ab37647) was used in western blot on human samples (fig 1a). Biochem Biophys Res Commun (2016) ncbi
domestic rabbit monoclonal (EPR12206)
  • immunohistochemistry; human; fig 5
  • western blot; human; fig 2
Abcam AGER antibody (abcam, ab172473) was used in immunohistochemistry on human samples (fig 5) and in western blot on human samples (fig 2). Oncotarget (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A11)
  • western blot; human; 1:1000; fig 6e
Santa Cruz Biotechnology AGER antibody (Santa Cruz Biotechnology, sc-80652) was used in western blot on human samples at 1:1000 (fig 6e). Cell Mol Life Sci (2022) ncbi
mouse monoclonal (A-9)
  • western blot; rat; loading ...; fig 4b
Santa Cruz Biotechnology AGER antibody (Santa, sc-365154) was used in western blot on rat samples (fig 4b). Aging (Albany NY) (2020) ncbi
mouse monoclonal (A-9)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5a
Santa Cruz Biotechnology AGER antibody (Santa Cruz, sc-365154) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5a). elife (2019) ncbi
mouse monoclonal (A-9)
  • western blot; mouse; loading ...; fig s13b
Santa Cruz Biotechnology AGER antibody (Santa Cruz, sc-365154) was used in western blot on mouse samples (fig s13b). Arterioscler Thromb Vasc Biol (2017) ncbi
mouse monoclonal (RD9C 2)
  • western blot; human; fig 1
Santa Cruz Biotechnology AGER antibody (santa Cruz, RD9C 2) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (RD9C 2)
  • immunocytochemistry; rat; 1:100; fig 2
  • western blot; rat; 1:100; fig 2
Santa Cruz Biotechnology AGER antibody (Santa Cruz Biotechnology, SC33662) was used in immunocytochemistry on rat samples at 1:100 (fig 2) and in western blot on rat samples at 1:100 (fig 2). Mol Med Rep (2016) ncbi
mouse monoclonal (RD9C 2)
  • western blot; human; fig 2
Santa Cruz Biotechnology AGER antibody (Santa Cruz, RD9C 2) was used in western blot on human samples (fig 2). Int J Mol Sci (2015) ncbi
mouse monoclonal (9A11)
  • immunohistochemistry - paraffin section; human; 1:500
  • western blot; human; 1:1000
Santa Cruz Biotechnology AGER antibody (Santa Cruz Biotechnology, sc-80653) was used in immunohistochemistry - paraffin section on human samples at 1:500 and in western blot on human samples at 1:1000. Breast Cancer Res Treat (2013) ncbi
mouse monoclonal (A11)
  • western blot; human
Santa Cruz Biotechnology AGER antibody (Santa Cruz, A11) was used in western blot on human samples . Biochim Biophys Acta (2013) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:300; fig 5c
R&D Systems AGER antibody (R&D, AF1145) was used in immunohistochemistry on mouse samples at 1:300 (fig 5c). Sci Transl Med (2022) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1f
R&D Systems AGER antibody (R&D, AF1179) was used in immunohistochemistry - paraffin section on human samples (fig 1f). J Neuroinflammation (2021) ncbi
Articles Reviewed
  1. Wakao S, Oguma Y, Kushida Y, Kuroda Y, Tatsumi K, Dezawa M. Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame. Cell Mol Life Sci. 2022;79:542 pubmed publisher
  2. Dinnon K, Leist S, Okuda K, Dang H, Fritch E, Gully K, et al. SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice. Sci Transl Med. 2022;14:eabo5070 pubmed publisher
  3. Zhao L, Li Y, Xu T, Lv Q, Bi X, Liu X, et al. Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ1 signaling pathway in diabetic atherosclerosis. Mol Med. 2022;28:4 pubmed publisher
  4. Zhao Y, Li W, Zhang D. Gycyrrhizic acid alleviates atherosclerotic lesions in rats with diabetes mellitus. Mol Med Rep. 2021;24: pubmed publisher
  5. Liu M, Shan M, Zhang Y, Guo Z. Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma. J Inflamm Res. 2021;14:3891-3904 pubmed publisher
  6. MacLean M, Juranek J, Cuddapah S, López Díez R, Ruiz H, Hu J, et al. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner. J Neuroinflammation. 2021;18:139 pubmed publisher
  7. Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed publisher
  8. Xue L, Guo W, Li L, Ou S, Zhu T, Cai L, et al. Metabolomic profiling identifies a novel mechanism for heat stroke‑related acute kidney injury. Mol Med Rep. 2021;23: pubmed publisher
  9. Zhang S, Hu L, Jiang J, Li H, Wu Q, Ooi K, et al. HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia. J Neuroinflammation. 2020;17:15 pubmed publisher
  10. Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher
  11. Ackerman J, Nichols A, Studentsova V, Best K, Knapp E, Loiselle A. Cell non-autonomous functions of S100a4 drive fibrotic tendon healing. elife. 2019;8: pubmed publisher
  12. Sakurai M, Miki Y, Takagi K, Suzuki T, Ishida T, Ohuchi N, et al. Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment. Breast Cancer Res. 2017;19:70 pubmed publisher
  13. Jiang P, Zhang D, Qiu H, Yi X, Zhang Y, Cao Y, et al. Tiron ameliorates high glucose-induced cardiac myocyte apoptosis by PKCδ-dependent inhibition of osteopontin. Clin Exp Pharmacol Physiol. 2017;44:760-770 pubmed publisher
  14. He Y, Wang X, Zhang J, Liu Z, Pan W, Shen Y, et al. Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs. Arterioscler Thromb Vasc Biol. 2017;37:717-729 pubmed publisher
  15. Sundar I, Javed F, Romanos G, Rahman I. E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts. Oncotarget. 2016;7:77196-77204 pubmed publisher
  16. Zhou Z, Tang Y, Jin X, Chen C, Lu Y, Liu L, et al. Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NF?B Pathway Suppression. J Diabetes Res. 2016;2016:4847812 pubmed
  17. Kim J, Kim C, Sohn E, Kim J. Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes. Mol Med Rep. 2016;14:3655-61 pubmed publisher
  18. Nishida T, Tsubota M, Kawaishi Y, Yamanishi H, Kamitani N, Sekiguchi F, et al. Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats. Toxicology. 2016;365:48-58 pubmed publisher
  19. Herwig N, Belter B, Pietzsch J. Extracellular S100A4 affects endothelial cell integrity and stimulates transmigration of A375 melanoma cells. Biochem Biophys Res Commun. 2016;477:963-969 pubmed publisher
  20. Serban A, Stanca L, Geicu O, Munteanu M, Dinischiotu A. RAGE and TGF-β1 Cross-Talk Regulate Extracellular Matrix Turnover and Cytokine Synthesis in AGEs Exposed Fibroblast Cells. PLoS ONE. 2016;11:e0152376 pubmed publisher
  21. Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
  22. Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, et al. Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep. 2016;13:1593-601 pubmed publisher
  23. Serban A, Stanca L, Geicu O, Dinischiotu A. AGEs-Induced IL-6 Synthesis Precedes RAGE Up-Regulation in HEK 293 Cells: An Alternative Inflammatory Mechanism?. Int J Mol Sci. 2015;16:20100-17 pubmed publisher
  24. Yin C, Li H, Zhang B, Liu Y, Lu G, Lu S, et al. RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial-mesenchymal transition. Breast Cancer Res Treat. 2013;142:297-309 pubmed publisher
  25. Chung T, Choi H, Kim C, Jeong H, Ha K. Lipocalin-2 elicited by advanced glycation end-products promotes the migration of vascular smooth muscle cells. Biochim Biophys Acta. 2013;1833:3386-3395 pubmed publisher