This is a Validated Antibody Database (VAD) review about human ADAMTS4, based on 3 published articles (read how Labome selects the articles), using ADAMTS4 antibody in all methods. It is aimed to help Labome visitors find the most suited ADAMTS4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ADAMTS4 synonym: ADAMTS-2; ADAMTS-4; ADMP-1; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; aggrecanase-1

Abcam
rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 1d
  • western blot; human; loading ...; fig 1a
Abcam ADAMTS4 antibody (Abcam, ab185722) was used in immunohistochemistry on human samples (fig 1d) and in western blot on human samples (fig 1a). Int J Mol Sci (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 1
In order to characterize the epithelial gain of MEKK3-KLF2/4 signaling due to cerebral cavernous malformations, Abcam ADAMTS4 antibody (Abcam, ab28285) was used in western blot on mouse samples at 1:1000 (fig 1). Nature (2016) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; human
In order to investigate the effect of IL-33 on the expression of ADAMTS-1, -4 and -5 in human macrophages and atherosclerotic lesions, Invitrogen ADAMTS4 antibody (Thermo Fisher Scientific, PA1-1749) was used in immunohistochemistry - paraffin section on human samples . Int J Biochem Cell Biol (2014) ncbi
Articles Reviewed
  1. Lu W, Shi J, Zhang J, Lv Z, Guo F, Huang H, et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci. 2016;17: pubmed
  2. Zhou Z, Tang A, Wong W, Bamezai S, Goddard L, Shenkar R, et al. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016;532:122-6 pubmed publisher
  3. Ashlin T, Buckley M, Salter R, Johnson J, Kwan A, Ramji D. The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1, -4 and -5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase an. Int J Biochem Cell Biol. 2014;46:113-23 pubmed publisher