This is a Validated Antibody Database (VAD) review about human ADAM12, based on 7 published articles (read how Labome selects the articles), using ADAM12 antibody in all methods. It is aimed to help Labome visitors find the most suited ADAM12 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ADAM12 synonym: ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alpha; metalloprotease-disintegrin 12 transmembrane

Proteintech Group
rabbit polyclonal
  • flow cytometry; rat; fig 3b
Proteintech Group ADAM12 antibody (Proteintech Group, 14139-1-AP) was used in flow cytometry on rat samples (fig 3b). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:500
In order to investigate the signalling pathways involved in the development of invasive trophoblasts, Proteintech Group ADAM12 antibody (Proteintech Group, 14139-1-AP) was used in western blot on human samples at 1:500. Mol Hum Reprod (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000
Proteintech Group ADAM12 antibody (Proteintech Group, 14139-1-AP) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Biol Reprod (2014) ncbi
Abcam
rabbit polyclonal
  • flow cytometry; human; 1:500; fig 5
Abcam ADAM12 antibody (Abcam, #39155) was used in flow cytometry on human samples at 1:500 (fig 5). Am J Physiol Heart Circ Physiol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; fig 1b
  • western blot; rat; fig 1d
  • immunohistochemistry - paraffin section; mouse; fig 4c
Abcam ADAM12 antibody (Abcam, ab39155) was used in immunohistochemistry - paraffin section on rat samples (fig 1b), in western blot on rat samples (fig 1d) and in immunohistochemistry - paraffin section on mouse samples (fig 4c). Stem Cell Res Ther (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; rat
  • western blot; rat; 1:1000
Abcam ADAM12 antibody (Abcam, ab39155) was used in immunohistochemistry on rat samples and in western blot on rat samples at 1:1000. PLoS ONE (2013) ncbi
R&D Systems
mouse monoclonal (632525)
  • flow cytometry; human; loading ...; fig 1a
In order to demonstrate that ADAM12 supports the cancer stem cell phenotype in claudin-low breast cancer cells via modulation of the epidermal growth factor receptor pathway, R&D Systems ADAM12 antibody (R&D Systems, 632525) was used in flow cytometry on human samples (fig 1a). Mol Cancer (2017) ncbi
Articles Reviewed
  1. Duhachek Muggy S, Qi Y, Wise R, Alyahya L, Li H, Hodge J, et al. Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer. Mol Cancer. 2017;16:32 pubmed publisher
  2. Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, et al. Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep. 2017;7:40295 pubmed publisher
  3. Dokun A, Chen L, Okutsu M, Farber C, Hazarika S, Jones W, et al. ADAM12: a genetic modifier of preclinical peripheral arterial disease. Am J Physiol Heart Circ Physiol. 2015;309:H790-803 pubmed publisher
  4. Brzoska E, Kowalski K, Markowska Zagrajek A, Kowalewska M, Archacki R, Plaskota I, et al. Sdf-1 (CXCL12) induces CD9 expression in stem cells engaged in muscle regeneration. Stem Cell Res Ther. 2015;6:46 pubmed publisher
  5. Velicky P, Haider S, Otti G, Fiala C, Pollheimer J, Knöfler M. Notch-dependent RBPJ? inhibits proliferation of human cytotrophoblasts and their differentiation into extravillous trophoblasts. Mol Hum Reprod. 2014;20:756-66 pubmed publisher
  6. Biadasiewicz K, Fock V, Dekan S, Proestling K, Velicky P, Haider S, et al. Extravillous trophoblast-associated ADAM12 exerts pro-invasive properties, including induction of integrin beta 1-mediated cellular spreading. Biol Reprod. 2014;90:101 pubmed publisher
  7. Przewoźniak M, Czaplicka I, Czerwinska A, Markowska Zagrajek A, Moraczewski J, Stremińska W, et al. Adhesion proteins--an impact on skeletal myoblast differentiation. PLoS ONE. 2013;8:e61760 pubmed publisher