This is a Validated Antibody Database (VAD) review about human ACVR2B, based on 5 published articles (read how Labome selects the articles), using ACVR2B antibody in all methods. It is aimed to help Labome visitors find the most suited ACVR2B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ACVR2B synonym: ACTRIIB; ActR-IIB; HTX4; activin receptor type-2B; activin A receptor, type IIB

Abcam
rabbit monoclonal (EPR10739)
  • western blot; rat; 1:1000; loading ...; fig 3c
Abcam ACVR2B antibody (Abcam, ab180185) was used in western blot on rat samples at 1:1000 (fig 3c). Exp Ther Med (2018) ncbi
mouse monoclonal
  • western blot; mouse; 1:1000; loading ...; tbl 2
Abcam ACVR2B antibody (Abcam, ab76940) was used in western blot on mouse samples at 1:1000 (tbl 2). Endocrinology (2017) ncbi
R&D Systems
mouse monoclonal (60408)
  • western blot; human; 1:1000; loading ...; fig s2e
R&D Systems ACVR2B antibody (R&D Systems, MAB3392) was used in western blot on human samples at 1:1000 (fig s2e). Dev Cell (2017) ncbi
goat polyclonal
  • immunohistochemistry; human
In order to examine the mechanism of the inhibin and activin signalling pathway in cancers, R&D Systems ACVR2B antibody (R&D, AF-339) was used in immunohistochemistry on human samples . Mol Hum Reprod (2014) ncbi
Sigma-Aldrich
goat polyclonal
  • western blot; mouse; loading ...; fig EV4c
Sigma-Aldrich ACVR2B antibody (Sigma-Aldrich, A0457) was used in western blot on mouse samples (fig EV4c). EMBO Mol Med (2017) ncbi
Articles Reviewed
  1. Yang J, Sun L, Fan X, Yin B, Kang Y, Tang L, et al. Effect of exercise on bone in poorly controlled type 1 diabetes mediated by the ActRIIB/Smad signaling pathway. Exp Ther Med. 2018;16:3686-3693 pubmed publisher
  2. Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
  3. Singh R, Braga M, Reddy S, Lee S, Parveen M, Grijalva V, et al. Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues. Endocrinology. 2017;158:1217-1230 pubmed publisher
  4. Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed publisher
  5. Marino F, Risbridger G, Gold E. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. Mol Hum Reprod. 2014;20:1223-37 pubmed publisher