This is a Validated Antibody Database (VAD) review about human ABCG2, based on 37 published articles (read how Labome selects the articles), using ABCG2 antibody in all methods. It is aimed to help Labome visitors find the most suited ABCG2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ABCG2 synonym: ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1

Santa Cruz Biotechnology
mouse monoclonal (BXP-21)
  • immunohistochemistry; human; 1:150; loading ...; fig 5a
Santa Cruz Biotechnology ABCG2 antibody (SantaCruz, sc-58222) was used in immunohistochemistry on human samples at 1:150 (fig 5a). J Clin Med (2022) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; loading ...; fig 5f
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, sc-18841) was used in flow cytometry on human samples (fig 5f). Exp Mol Med (2017) ncbi
mouse monoclonal (B-1)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, sc-377176) was used in western blot on human samples (fig 1b). Exp Mol Med (2017) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; fig 5b
Santa Cruz Biotechnology ABCG2 antibody (SantaCruz, sc-58222) was used in western blot on human samples (fig 5b). Mol Pharmacol (2017) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; 1:500; fig 4
Santa Cruz Biotechnology ABCG2 antibody (santa Cruz, sc-58222) was used in western blot on human samples at 1:500 (fig 4). Oncol Lett (2016) ncbi
mouse monoclonal (B-1)
  • western blot; human; fig 4
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, sc-377176) was used in western blot on human samples (fig 4). Onco Targets Ther (2016) ncbi
mouse monoclonal (6D171)
  • immunocytochemistry; human; 1:3000; fig s2
  • western blot; human; 1:1000; fig 1
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, 6D171) was used in immunocytochemistry on human samples at 1:3000 (fig s2) and in western blot on human samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
rat monoclonal (BXP-53)
  • western blot; human; fig 1
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz Biotechnology, sc-58224) was used in western blot on human samples (fig 1). J Korean Med Sci (2016) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; 1:50; fig 1b
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, 5D3) was used in flow cytometry on human samples at 1:50 (fig 1b). Curr Cancer Drug Targets (2016) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; fig 1
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, BXP-21) was used in western blot on human samples (fig 1). PLoS ONE (2015) ncbi
rat monoclonal (BXP-53)
  • western blot; human
Santa Cruz Biotechnology ABCG2 antibody (SANTA Cruz, sc-58224) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (5D3)
  • western blot; human; 1:1000
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz Biotechnology, sc-18841) was used in western blot on human samples at 1:1000. Mol Med Rep (2014) ncbi
mouse monoclonal (BXP-21)
  • immunohistochemistry - paraffin section; human; 1:500
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, SC-58222) was used in immunohistochemistry - paraffin section on human samples at 1:500. Cancer Med (2014) ncbi
mouse monoclonal (6D170)
  • western blot; human; 1:200
Santa Cruz Biotechnology ABCG2 antibody (Santa Cruz, sc-69989) was used in western blot on human samples at 1:200. Am J Pathol (2012) ncbi
Abcam
domestic rabbit monoclonal
  • western blot; human; 1:1000; loading ...; fig s4c, s4d
Abcam ABCG2 antibody (abcam, ab207732) was used in western blot on human samples at 1:1000 (fig s4c, s4d). Front Oncol (2021) ncbi
domestic rabbit monoclonal
  • western blot; human; loading ...; fig 3d, 4d
Abcam ABCG2 antibody (Abcam, ab207732) was used in western blot on human samples (fig 3d, 4d). J Cancer (2020) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; 1:1000; loading ...; fig 3a
Abcam ABCG2 antibody (Abcam, ab3380) was used in western blot on human samples at 1:1000 (fig 3a). Sci Rep (2019) ncbi
mouse monoclonal (BXP-21)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig s4
Abcam ABCG2 antibody (Abcam, ab3380) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig s4). Epilepsia (2018) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; fig 9c
  • western blot; mouse; loading ...; fig 9c
Abcam ABCG2 antibody (Abcam, ab3380) was used in western blot on human samples (fig 9c) and in western blot on mouse samples (fig 9c). PLoS ONE (2017) ncbi
mouse monoclonal (BXP-21)
  • flow cytometry; human; 1:200; loading ...; fig 2b
  • immunocytochemistry; human; 1:200; loading ...; fig 1b
  • western blot; human; loading ...; fig 4b
In order to study the contribution of CD133 and ABCG2 in lung cancer tumorospheres, Abcam ABCG2 antibody (Abcam, ab3380) was used in flow cytometry on human samples at 1:200 (fig 2b), in immunocytochemistry on human samples at 1:200 (fig 1b) and in western blot on human samples (fig 4b). Mol Med Rep (2016) ncbi
mouse monoclonal (BXP-21)
  • immunohistochemistry - paraffin section; human; 1:500; fig 5
  • immunocytochemistry; human; 1:3000; fig 2
  • western blot; human; 1:1000; fig 1
Abcam ABCG2 antibody (Abcam, BXP-21) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 5), in immunocytochemistry on human samples at 1:3000 (fig 2) and in western blot on human samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (1H2)
  • western blot; human; loading ...; fig 2a
Abcam ABCG2 antibody (Abcam, ab130244) was used in western blot on human samples (fig 2a). Oncol Lett (2016) ncbi
mouse monoclonal (BXP-21)
  • western blot; human; fig 3
Abcam ABCG2 antibody (Abcam, ab3380) was used in western blot on human samples (fig 3). Cell Death Dis (2015) ncbi
mouse monoclonal (BXP-21)
  • flow cytometry; human; fig 2
Abcam ABCG2 antibody (abcam, Ab3380) was used in flow cytometry on human samples (fig 2). Oncogenesis (2015) ncbi
mouse monoclonal (BXP-21)
  • immunocytochemistry; human; 1:1000
Abcam ABCG2 antibody (Abcam, AB3380) was used in immunocytochemistry on human samples at 1:1000. J Mol Endocrinol (2014) ncbi
mouse monoclonal (BXP-21)
  • flow cytometry; human
Abcam ABCG2 antibody (Abcam, ab3380) was used in flow cytometry on human samples . Cell Death Dis (2013) ncbi
mouse monoclonal (BXP-21)
  • immunohistochemistry - paraffin section; human; 1:40
  • western blot; human; 1:50; fig s4
Abcam ABCG2 antibody (Abcam, Ab3380) was used in immunohistochemistry - paraffin section on human samples at 1:40 and in western blot on human samples at 1:50 (fig s4). PLoS ONE (2013) ncbi
mouse monoclonal (BXP-21)
  • western blot; rat
Abcam ABCG2 antibody (Abcam, BXP21) was used in western blot on rat samples . Biochem Pharmacol (2012) ncbi
Miltenyi Biotec
mouse monoclonal (5D3)
  • flow cytometry; human; 1:40; loading ...; fig 2g
Miltenyi Biotec ABCG2 antibody (Miltenyi Biotec, 130-105-010) was used in flow cytometry on human samples at 1:40 (fig 2g). Nat Commun (2021) ncbi
BioLegend
mouse monoclonal (5D3)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BioLegend ABCG2 antibody (BioLegen d, 332008) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human
In order to identify the cell surface markers in synovial mesenchymal stem cells, BioLegend ABCG2 antibody (Biolegend, 332008) was used in flow cytometry on human samples . Cytometry A (2015) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human
BioLegend ABCG2 antibody (Biolegend, 5D3) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
Invitrogen
mouse monoclonal (5D3)
  • flow cytometry; dogs; loading ...; fig 5
In order to evaluate the use of valspodar to treat canine B-cell lymphoma, Invitrogen ABCG2 antibody (EBioscience, 12-8888-82) was used in flow cytometry on dogs samples (fig 5). F1000Res (2015) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; fig 1
Invitrogen ABCG2 antibody (eBiosceince, 5D3) was used in flow cytometry on human samples (fig 1). Sci Rep (2016) ncbi
Abnova
mouse polyclonal
  • western blot; rat; loading ...; fig 6a
  • western blot; African green monkey; 1:2500; loading ...; fig 6a
Abnova ABCG2 antibody (Abnova, H00009429-B01P) was used in western blot on rat samples (fig 6a) and in western blot on African green monkey samples at 1:2500 (fig 6a). Pharmaceutics (2021) ncbi
mouse monoclonal (3G8)
  • western blot; human; 1:500; fig 1
Abnova ABCG2 antibody (Abnova, 3G8) was used in western blot on human samples at 1:500 (fig 1). Sci Rep (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology ABCG2 antibody (cell signalling, 4477) was used in western blot on human samples (fig 5a). Oncotarget (2017) ncbi
BD Biosciences
mouse monoclonal (5D3)
  • flow cytometry; human; loading ...; fig 5b
BD Biosciences ABCG2 antibody (BD Pharmingen, 561451) was used in flow cytometry on human samples (fig 5b). Oncotarget (2017) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; fig 5
BD Biosciences ABCG2 antibody (BD Bioscience, 5D3) was used in flow cytometry on human samples (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; loading ...; fig 5b
BD Biosciences ABCG2 antibody (BD Biosciences, 561180) was used in flow cytometry on human samples (fig 5b). Oncotarget (2015) ncbi
mouse monoclonal (5D3)
  • flow cytometry; human; 5 ul
BD Biosciences ABCG2 antibody (BD Bioscience, 561451) was used in flow cytometry on human samples at 5 ul. Cancer Med (2014) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig s3
  • western blot; human; 1:5000; fig 1
MilliporeSigma ABCG2 antibody (Sigma-Aldrich, B7185) was used in immunocytochemistry on human samples at 1:500 (fig s3) and in western blot on human samples at 1:5000 (fig 1). Sci Rep (2016) ncbi
Articles Reviewed
  1. Malinowski D, Grzeg xf3 x142 kowski P, Piotrowska K, S x142 ojewski M, Dro x17a dzik M. Membrane Transporters and Carriers in Human Seminal Vesicles. J Clin Med. 2022;11: pubmed publisher
  2. Watanabe D, Nakagawa S, Morofuji Y, Tóth A, Vastag M, Aruga J, et al. Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes. Pharmaceutics. 2021;13: pubmed publisher
  3. Goel S, Bhatia V, Kundu S, Biswas T, Carskadon S, Gupta N, et al. Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progression. Nat Commun. 2021;12:5325 pubmed publisher
  4. Ding B, Bao C, Jin L, Xu L, Fan W, Lou W. CASK Silence Overcomes Sorafenib Resistance of Hepatocellular Carcinoma Through Activating Apoptosis and Autophagic Cell Death. Front Oncol. 2021;11:681683 pubmed publisher
  5. Song S, Li Y, Zhang K, Zhang X, Huang Y, Xu M, et al. Cancer Stem Cells of Diffuse Large B Cell Lymphoma Are Not Enriched in the CD45+CD19- cells but in the ALDHhigh Cells. J Cancer. 2020;11:142-152 pubmed publisher
  6. Kitajima Y, Ishii T, Kohda T, Ishizuka M, Yamazaki K, Nishimura Y, et al. Mechanistic study of PpIX accumulation using the JFCR39 cell panel revealed a role for dynamin 2-mediated exocytosis. Sci Rep. 2019;9:8666 pubmed publisher
  7. Weidner L, Kannan P, Mitsios N, Kang S, Hall M, Theodore W, et al. The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue. Epilepsia. 2018;59:1507-1517 pubmed publisher
  8. Sekhar G, Georgian A, Sanderson L, Vizcay Barrena G, Brown R, Muresan P, et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS ONE. 2017;12:e0173474 pubmed publisher
  9. Ito D, Childress M, Mason N, Winter A, O BRIEN T, Henson M, et al. A double blinded, placebo-controlled pilot study to examine reduction of CD34 +/CD117 +/CD133 + lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma. F1000Res. 2015;4:42 pubmed publisher
  10. Yang K, Chen Y, To K, Wang F, Li D, Chen L, et al. Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo. Exp Mol Med. 2017;49:e303 pubmed publisher
  11. Zhong Y, Li X, Ji Y, Li X, Li Y, Yu D, et al. Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers. Oncotarget. 2017;8:13344-13356 pubmed publisher
  12. Wang M, Li G, Yang Z, Wang L, Zhang L, Wang T, et al. Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer. Oncotarget. 2017;8:8083-8094 pubmed publisher
  13. Neradugomma N, Liao M, Mao Q. Buprenorphine, Norbuprenorphine, R-Methadone, and S-Methadone Upregulate BCRP/ABCG2 Expression by Activating Aryl Hydrocarbon Receptor in Human Placental Trophoblasts. Mol Pharmacol. 2017;91:237-249 pubmed publisher
  14. Gao C, Zhang J, Wang Q, Ren C. Overexpression of lncRNA NEAT1 mitigates multidrug resistance by inhibiting ABCG2 in leukemia. Oncol Lett. 2016;12:1051-1057 pubmed
  15. Zhao W, Luo Y, Li B, Zhang T. Tumorigenic lung tumorospheres exhibit stem-like features with significantly increased expression of CD133 and ABCG2. Mol Med Rep. 2016;14:2598-606 pubmed publisher
  16. Jiang P, Wang P, Sun X, Yuan Z, Zhan R, Ma X, et al. Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy. Onco Targets Ther. 2016;9:3501-9 pubmed publisher
  17. Cederbye C, Palshof J, Hansen T, Duun Henriksen A, Linnemann D, Stenvang J, et al. Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue. Sci Rep. 2016;6:26997 pubmed publisher
  18. Jia M, Wei Z, Liu P, Zhao X. Silencing of ABCG2 by MicroRNA-3163 Inhibits Multidrug Resistance in Retinoblastoma Cancer Stem Cells. J Korean Med Sci. 2016;31:836-42 pubmed publisher
  19. Park S, Kim J, Kim N, Yang K, Shim J, Heo K. Estradiol, TGF-?1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration. Oncol Lett. 2016;11:1895-1902 pubmed
  20. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  21. Kumar J, Wei B, Madigan J, Simpson R, Hall M, Gottesman M. Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Sci Rep. 2016;6:20418 pubmed publisher
  22. Fanelli M, Hattinger C, Vella S, Tavanti E, Michelacci F, Gudeman B, et al. Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. Curr Cancer Drug Targets. 2016;16:261-74 pubmed
  23. Liu Z, Hu J, Liang J, Zhou A, Li M, Yan S, et al. Far upstream element-binding protein 1 is a prognostic biomarker and promotes nasopharyngeal carcinoma progression. Cell Death Dis. 2015;6:e1920 pubmed publisher
  24. Denkovskij J, Rudys R, Bernotiene E, Minderis M, Bagdonas S, Kirdaite G. Cell surface markers and exogenously induced PpIX in synovial mesenchymal stem cells. Cytometry A. 2015;87:1001-11 pubmed publisher
  25. Su Y, Chang Y, Lin W, Liang C, Lee J. An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype. Oncogenesis. 2015;4:e157 pubmed publisher
  26. Takahashi R, Miyazaki H, Takeshita F, Yamamoto Y, Minoura K, Ono M, et al. Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1. Nat Commun. 2015;6:7318 pubmed publisher
  27. Ayadi M, Bouygues A, Ouaret D, Ferrand N, Chouaib S, Thiery J, et al. Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors. Oncotarget. 2015;6:18518-33 pubmed
  28. Rigalli J, Ciriaci N, Arias A, Ceballos M, Villanueva S, Luquita M, et al. Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity. PLoS ONE. 2015;10:e0119502 pubmed publisher
  29. Jin J, Zhang W, Wong K, Kwak M, van Driel I, Yu Q. Inhibition of breast cancer resistance protein (ABCG2) in human myeloid dendritic cells induces potent tolerogenic functions during LPS stimulation. PLoS ONE. 2014;9:e104753 pubmed publisher
  30. Mato E, Gonzalez C, Moral A, Pérez J, Bell O, Lerma E, et al. ABCG2/BCRP gene expression is related to epithelial-mesenchymal transition inducer genes in a papillary thyroid carcinoma cell line (TPC-1). J Mol Endocrinol. 2014;52:289-300 pubmed publisher
  31. Guo S, Yu Y, Zhang N, Cui Y, Zhai L, Li H, et al. Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen. Biochim Biophys Acta. 2014;1841:836-46 pubmed publisher
  32. Liu L, Zuo L, Guo J. ABCG2 gene amplification and expression in esophageal cancer cells with acquired adriamycin resistance. Mol Med Rep. 2014;9:1299-304 pubmed publisher
  33. Dalley A, Pitty L, Major A, Abdulmajeed A, Farah C. Expression of ABCG2 and Bmi-1 in oral potentially malignant lesions and oral squamous cell carcinoma. Cancer Med. 2014;3:273-83 pubmed publisher
  34. Liu H, Zhang W, Jia Y, Yu Q, Grau G, Peng L, et al. Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis. 2013;4:e857 pubmed publisher
  35. Veringa S, Biesmans D, van Vuurden D, Jansen M, Wedekind L, Horsman I, et al. In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma. PLoS ONE. 2013;8:e61512 pubmed publisher
  36. Rosales R, Monte M, Blazquez A, Briz O, Marin J. ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds. Biochem Pharmacol. 2012;84:1651-9 pubmed publisher
  37. Liu S, Tetzlaff M, Cui R, Xu X. miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1. Am J Pathol. 2012;181:1823-35 pubmed publisher