This is a Validated Antibody Database (VAD) review about human ABCC1, based on 33 published articles (read how Labome selects the articles), using ABCC1 antibody in all methods. It is aimed to help Labome visitors find the most suited ABCC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ABCC1 synonym: ABC29; ABCC; GS-X; MRP; MRP1; multidrug resistance-associated protein 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; LTC4 transporter; leukotriene C(4) transporter

Abcam
rat monoclonal (MRPr1)
  • western blot; human; 1:500; loading ...; fig 6a
Abcam ABCC1 antibody (Abcam, ab3368) was used in western blot on human samples at 1:500 (fig 6a). Cell Rep (2019) ncbi
mouse monoclonal (IU2H10)
  • western blot; human; 1:100; loading ...; fig 3a
Abcam ABCC1 antibody (Abcam, IU2H10) was used in western blot on human samples at 1:100 (fig 3a). Nat Commun (2017) ncbi
mouse monoclonal (IU2H10)
  • western blot; human; 1:1000; fig 3
Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on human samples at 1:1000 (fig 3). Biomed Res Int (2016) ncbi
mouse monoclonal (MRPm5)
  • western blot; human; loading ...; fig 1d
Abcam ABCC1 antibody (Abcam, MRPm5) was used in western blot on human samples (fig 1d). Oncotarget (2016) ncbi
mouse monoclonal (IU2H10)
  • immunohistochemistry - paraffin section; human; fig 3
  • western blot; human; fig 1
Abcam ABCC1 antibody (Abcam, ab32574) was used in immunohistochemistry - paraffin section on human samples (fig 3) and in western blot on human samples (fig 1). Oncol Rep (2016) ncbi
mouse monoclonal (IU2H10)
  • western blot; human; fig 5
Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on human samples (fig 5). BMC Complement Altern Med (2016) ncbi
mouse monoclonal (MRPm5)
  • flow cytometry; human; 1:20; fig 1b
  • western blot; human; 1:50; fig s1
Abcam ABCC1 antibody (Abcam, MRPm5) was used in flow cytometry on human samples at 1:20 (fig 1b) and in western blot on human samples at 1:50 (fig s1). Curr Cancer Drug Targets (2016) ncbi
mouse monoclonal (IU2H10)
  • western blot; mouse; fig s1
  • western blot; human; 1:100; fig s1
In order to analyze multidrug resistant human cancer cells and autocrime cytokine/JAK/STAT-signaling induces kynurenin synthesis, Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on mouse samples (fig s1) and in western blot on human samples at 1:100 (fig s1). PLoS ONE (2015) ncbi
mouse monoclonal (IU2H10)
  • western blot; human; fig 4
Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on human samples (fig 4). Oncol Rep (2015) ncbi
mouse monoclonal (IU2H10)
  • immunohistochemistry - paraffin section; human; 1:500
Abcam ABCC1 antibody (Abcam, ab32574) was used in immunohistochemistry - paraffin section on human samples at 1:500. PLoS ONE (2014) ncbi
mouse monoclonal (IU2H10)
  • western blot; human; fig 2
Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on human samples (fig 2). Mol Biol Rep (2013) ncbi
mouse monoclonal (IU2H10)
  • western blot; human
Abcam ABCC1 antibody (Abcam, ab32574) was used in western blot on human samples . Cancer Cell Int (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (9)
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz, sc-136447) was used in western blot on human samples at 1:1000 (fig 4a). Apoptosis (2017) ncbi
mouse monoclonal (QCRL-1)
  • western blot; human; loading ...; fig s3e
Santa Cruz Biotechnology ABCC1 antibody (SantaCruz, sc-18835) was used in western blot on human samples (fig s3e). Nat Med (2017) ncbi
mouse monoclonal (QCRL-2)
  • immunohistochemistry - paraffin section; human; fig 6b
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz Biotechnology, sc-18836) was used in immunohistochemistry - paraffin section on human samples (fig 6b). Oncotarget (2016) ncbi
mouse monoclonal (QCRL-1)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz Biotechnology, sc-18835) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
mouse monoclonal (IU2H10)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5d
  • western blot; mouse; 1:100; loading ...; fig 5c
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz Biotechnology, sc-53130) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5d) and in western blot on mouse samples at 1:100 (fig 5c). Toxicol Appl Pharmacol (2016) ncbi
mouse monoclonal (QCRL-1)
  • western blot; human; fig 4
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz, sc-18835) was used in western blot on human samples (fig 4). Onco Targets Ther (2016) ncbi
mouse monoclonal (E-5)
  • western blot; human; 1:50; fig 3
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz, sc-365635) was used in western blot on human samples at 1:50 (fig 3). Exp Ther Med (2015) ncbi
mouse monoclonal (QCRL-1)
  • immunohistochemistry; human; 1:50; fig 1
Santa Cruz Biotechnology ABCC1 antibody (santa Cruz, sc18835) was used in immunohistochemistry on human samples at 1:50 (fig 1). BMC Cancer (2015) ncbi
mouse monoclonal (QCRL-1)
  • western blot; human; 1:200
Santa Cruz Biotechnology ABCC1 antibody (Santa Cruz Biotechnology, sc-18835) was used in western blot on human samples at 1:200. Br J Pharmacol (2014) ncbi
Enzo Life Sciences
rat monoclonal (MRPr1)
  • western blot; human; fig 1
Enzo Life Sciences ABCC1 antibody (Enzo Life Sciences, MRP1) was used in western blot on human samples (fig 1). Sci Rep (2016) ncbi
rat monoclonal (MRPr1)
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 1c
Enzo Life Sciences ABCC1 antibody (nzo Life Sciences, ALX-801-007-C125) was used in immunocytochemistry on human samples (fig 3d) and in western blot on human samples (fig 1c). FASEB J (2016) ncbi
mouse monoclonal (MRPm6)
  • western blot; human; 1:50; loading ...; fig 2a
Enzo Life Sciences ABCC1 antibody (nzo Life Sciences, ALX-801-013-C500) was used in western blot on human samples at 1:50 (fig 2a). FASEB J (2016) ncbi
rat monoclonal (MRPr1)
  • immunocytochemistry; human; 1:250
  • western blot; human
Enzo Life Sciences ABCC1 antibody (Enzo Life Sciences, MRPr1) was used in immunocytochemistry on human samples at 1:250 and in western blot on human samples . Pharm Res (2015) ncbi
rat monoclonal (MRPr1)
  • immunocytochemistry; mouse
  • western blot; mouse; 1:2000
Enzo Life Sciences ABCC1 antibody (Enzo Life Sciences, MRPr1) was used in immunocytochemistry on mouse samples and in western blot on mouse samples at 1:2000. J Pharmacol Exp Ther (2012) ncbi
rat monoclonal (MRPr1)
  • western blot; human; 1:400
Enzo Life Sciences ABCC1 antibody (Enzo Life Sciences, MRPr1) was used in western blot on human samples at 1:400. Drug Metab Dispos (2011) ncbi
rat monoclonal (MRPr1)
  • immunohistochemistry - paraffin section; human; 1:15
Enzo Life Sciences ABCC1 antibody (Alexis, ALX-801-007-C125) was used in immunohistochemistry - paraffin section on human samples at 1:15. Anticancer Res (2007) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; 1:500
In order to determine if metformin reverses the multidrug resistance observed in human hepatocellular carcinoma Bel-7402/5-fluorouracil cells, Invitrogen ABCC1 antibody (Thermo Fisher Scientific, PA5-30594) was used in western blot on human samples at 1:500. Mol Med Rep (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500
In order to determine if metformin could be used to treat intrahepatic cholangiocarcinoma, Invitrogen ABCC1 antibody (Thermo Fisher Scientific Inc, PA5-30594) was used in western blot on human samples at 1:500. Oncol Rep (2014) ncbi
EMD Millipore
mouse monoclonal (QCRL-1)
  • other; human; 1:50; fig 3b
EMD Millipore ABCC1 antibody (Millipore, MAB4100) was used in other on human samples at 1:50 (fig 3b). PLoS ONE (2017) ncbi
mouse monoclonal (QCRL-1)
  • immunocytochemistry; human; 1:25; fig 2h
In order to examine trafficking of cancer-targeting alkylphosphocholine analogues across the blood brain barrier, EMD Millipore ABCC1 antibody (Millipore, QCRL-1) was used in immunocytochemistry on human samples at 1:25 (fig 2h). Mol Pharm (2016) ncbi
mouse monoclonal (QCRL-1)
  • immunocytochemistry; human; 1:25; fig 2
In order to describe methods to differentiate and characterize hPSC-derived brain microvascular endothelial cells, EMD Millipore ABCC1 antibody (Millipore, QCRL1) was used in immunocytochemistry on human samples at 1:25 (fig 2). Methods (2016) ncbi
mouse monoclonal (QCRL-1)
  • flow cytometry; human
  • immunocytochemistry; human
EMD Millipore ABCC1 antibody (Millipore, MAB4100) was used in flow cytometry on human samples and in immunocytochemistry on human samples . Mol Cancer Ther (2015) ncbi
mouse monoclonal (MRPm6)
  • immunohistochemistry; human
EMD Millipore ABCC1 antibody (Millipore Corporation, MRPm6) was used in immunohistochemistry on human samples . Exp Oncol (2013) ncbi
Articles Reviewed
  1. Cao J, Poddar A, Magtanong L, Lumb J, Mileur T, Reid M, et al. A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Rep. 2019;26:1544-1556.e8 pubmed publisher
  2. Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, et al. The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells. Nat Commun. 2017;8:15663 pubmed publisher
  3. Lian W, Zhang L, Yang L, Chen W. AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. Apoptosis. 2017;22:933-941 pubmed publisher
  4. Midde N, Sinha N, Lukka P, Meibohm B, Kumar S. Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells. PLoS ONE. 2017;12:e0172628 pubmed publisher
  5. Göllner S, Oellerich T, Agrawal Singh S, Schenk T, Klein H, Rohde C, et al. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat Med. 2017;23:69-78 pubmed publisher
  6. Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  7. Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  8. Clark P, Al Ahmad A, Qian T, Zhang R, Wilson H, Weichert J, et al. Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model. Mol Pharm. 2016;13:3341-9 pubmed publisher
  9. Wang Y, Chen M, Zhang Y, Huo T, Fang Y, Jiao X, et al. Effects of realgar on GSH synthesis in the mouse hippocampus: Involvement of system XAG(-), system XC(-), MRP-1 and Nrf2. Toxicol Appl Pharmacol. 2016;308:91-101 pubmed publisher
  10. Jiang P, Wang P, Sun X, Yuan Z, Zhan R, Ma X, et al. Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy. Onco Targets Ther. 2016;9:3501-9 pubmed publisher
  11. Fouquet G, Debuysscher V, Ouled Haddou H, Eugenio M, Demey B, Singh A, et al. Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs. Oncotarget. 2016;7:32493-503 pubmed publisher
  12. Kataoka J, Shiraha H, Horiguchi S, Sawahara H, Uchida D, Nagahara T, et al. Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma. Oncol Rep. 2016;35:2576-82 pubmed publisher
  13. Abu N, Akhtar M, Yeap S, Lim K, Ho W, Abdullah M, et al. Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro. BMC Complement Altern Med. 2016;16:86 pubmed publisher
  14. Kumar J, Wei B, Madigan J, Simpson R, Hall M, Gottesman M. Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Sci Rep. 2016;6:20418 pubmed publisher
  15. Roundhill E, Turnbull D, Burchill S. Localization of MRP-1 to the outer mitochondrial membrane by the chaperone protein HSP90β. FASEB J. 2016;30:1712-23 pubmed publisher
  16. Liu X, Yue X, Chen S, Chen J, Li R. Significance of the expression of MRP1 and MRP2 in peripheral blood mononuclear cells of children with intractable epilepsy. Exp Ther Med. 2015;10:1784-1788 pubmed
  17. Fanelli M, Hattinger C, Vella S, Tavanti E, Michelacci F, Gudeman B, et al. Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. Curr Cancer Drug Targets. 2016;16:261-74 pubmed
  18. Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed publisher
  19. Kim B, Stephen S, Hanby A, Horgan K, Perry S, Richardson J, et al. Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy. BMC Cancer. 2015;15:634 pubmed publisher
  20. Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharm Res. 2015;32:2973-82 pubmed publisher
  21. Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, et al. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE. 2015;10:e0126159 pubmed publisher
  22. Loganzo F, Tan X, Sung M, Jin G, Myers J, Melamud E, et al. Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments. Mol Cancer Ther. 2015;14:952-63 pubmed publisher
  23. Wang C, Zhang W, Fu M, Yang A, Huang H, Xie J. Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression. Oncol Rep. 2015;33:383-90 pubmed publisher
  24. Ge J, Chen Z, Huang J, Chen J, Yuan W, Deng Z, et al. Upregulation of autophagy-related gene-5 (ATG-5) is associated with chemoresistance in human gastric cancer. PLoS ONE. 2014;9:e110293 pubmed publisher
  25. Ling S, Tian Y, Zhang H, Jia K, Feng T, Sun D, et al. Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel‑7402/5‑fluorouracil cells. Mol Med Rep. 2014;10:2891-7 pubmed publisher
  26. Zhang H, Patel A, Ma S, Li X, Zhang Y, Yang P, et al. In vitro, in vivo and ex vivo characterization of ibrutinib: a potent inhibitor of the efflux function of the transporter MRP1. Br J Pharmacol. 2014;171:5845-57 pubmed publisher
  27. Ling S, Feng T, Ke Q, Fan N, Li L, Li Z, et al. Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. Oncol Rep. 2014;31:2611-8 pubmed publisher
  28. Kovalev A, Tsvetaeva D, Grudinskaja T. Role of ABC-cassette transporters (MDR1, MRP1, BCRP) in the development of primary and acquired multiple drug resistance in patients with early and metastatic breast cancer. Exp Oncol. 2013;35:287-90 pubmed
  29. Li W, Zhong S, Wu Y, Xu W, Xu J, Tang J, et al. Systematic expression analysis of genes related to multidrug-resistance in isogenic docetaxel- and adriamycin-resistant breast cancer cell lines. Mol Biol Rep. 2013;40:6143-50 pubmed
  30. Lin S, Hoffmann K, Xiao Z, Jin N, Galli U, Mohr E, et al. MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma. Cancer Cell Int. 2013;13:3 pubmed publisher
  31. Gibson C, Hossain M, Richardson J, Aleksunes L. Inflammatory regulation of ATP binding cassette efflux transporter expression and function in microglia. J Pharmacol Exp Ther. 2012;343:650-60 pubmed publisher
  32. Mason C, Buhimschi I, Buhimschi C, Dong Y, Weiner C, Swaan P. ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition. Drug Metab Dispos. 2011;39:1000-7 pubmed publisher
  33. Roy S, Kenny E, Kennedy S, Larkin A, Ballot J, Perez De Villarreal M, et al. MDR1/P-glycoprotein and MRP-1 mRNA and protein expression in non-small cell lung cancer. Anticancer Res. 2007;27:1325-30 pubmed