This is a Validated Antibody Database (VAD) review about dogs claudin 2, based on 69 published articles (read how Labome selects the articles), using claudin 2 antibody in all methods. It is aimed to help Labome visitors find the most suited claudin 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Invitrogen
mouse monoclonal (12H12)
  • western blot knockout validation; human; 1:5000; loading ...; fig 2a
  • immunohistochemistry; human; 1:250; loading ...; fig 3a, 5d, s1
Invitrogen claudin 2 antibody (Thermofisher, 325600) was used in western blot knockout validation on human samples at 1:5000 (fig 2a) and in immunohistochemistry on human samples at 1:250 (fig 3a, 5d, s1). Commun Biol (2021) ncbi
Invitrogen
mouse monoclonal (12H12)
  • western blot knockout validation; human; 1:5000; loading ...; fig 2a
  • immunohistochemistry; human; 1:250; loading ...; fig 3a, 5d, s1
Invitrogen claudin 2 antibody (Thermofisher, 325600) was used in western blot knockout validation on human samples at 1:5000 (fig 2a) and in immunohistochemistry on human samples at 1:250 (fig 3a, 5d, s1). Commun Biol (2021) ncbi
domestic rabbit polyclonal (MH44)
  • immunohistochemistry - frozen section; mouse; 1:125; loading ...; fig 4d
  • western blot; mouse; 1:1000; loading ...; fig 4a
Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in immunohistochemistry - frozen section on mouse samples at 1:125 (fig 4d) and in western blot on mouse samples at 1:1000 (fig 4a). Am J Physiol Gastrointest Liver Physiol (2021) ncbi
domestic rabbit polyclonal (MH44)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6a
  • western blot; mouse; 1:500; loading ...; fig 6b
Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 6a) and in western blot on mouse samples at 1:500 (fig 6b). Cell Mol Gastroenterol Hepatol (2018) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs; fig 2
  • western blot; dogs; fig 2
In order to study the role of claudin-4 in tight junctions in MDCK cells, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunocytochemistry on dogs samples (fig 2) and in western blot on dogs samples (fig 2). PLoS ONE (2017) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; human; 1:100; loading ...; fig 2d
In order to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells, Invitrogen claudin 2 antibody (Thermo Fisher Scientific, 51-6100) was used in immunocytochemistry on human samples at 1:100 (fig 2d). Mol Vis (2017) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; human; loading ...; fig 5b
  • western blot; human; loading ...; fig 5a
In order to assess the effect of TNF-alpha on claudin-2 expression and tight junction function, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in immunocytochemistry on human samples (fig 5b) and in western blot on human samples (fig 5a). Int J Mol Sci (2017) ncbi
domestic rabbit polyclonal (MH44)
  • flow cytometry; human; 1:200; loading ...; fig 3a
In order to ascertain how claudin-6 is associated with MMP-2 activation and cell invasiveness, Invitrogen claudin 2 antibody (Invitrogen, 516100) was used in flow cytometry on human samples at 1:200 (fig 3a). Exp Cell Res (2017) ncbi
domestic rabbit polyclonal (MH44)
  • western blot; mouse; 1:500; loading ...; fig 2b
In order to show that Gata4 regulates barrier integrity in the mouse proximal intestinal epithelium, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in western blot on mouse samples at 1:500 (fig 2b). Sci Rep (2016) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; dogs; loading ...; fig 7a
  • western blot; dogs; loading ...; fig 1b
  • western blot; human; fig 1a
In order to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells, Invitrogen claudin 2 antibody (Zymed Laboratories, 51-6100) was used in immunocytochemistry on dogs samples (fig 7a), in western blot on dogs samples (fig 1b) and in western blot on human samples (fig 1a). J Biol Chem (2016) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; dogs; 1:200; loading ...; fig 2b
  • western blot; dogs; 1:1000; loading ...; fig 1f
In order to measure tight junction protein expression in canine duodenum, lung, liver, and kidney, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry - paraffin section on dogs samples at 1:200 (fig 2b) and in western blot on dogs samples at 1:1000 (fig 1f). Mol Med Rep (2016) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; fig 4E
  • immunocytochemistry; human; fig 2E
  • western blot; human; fig 1
In order to establish methods to assess claudin-2 expression and localization in human colon biopsy samples, Invitrogen claudin 2 antibody (Invitrogen, 32?C5600) was used in immunohistochemistry - paraffin section on human samples (fig 4E), in immunocytochemistry on human samples (fig 2E) and in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry; mouse; 7 ug/ml; loading ...; tbl s5
  • western blot; mouse; 3 ug/ml; loading ...; tbl s5
In order to explore the effects of mild chronic psychological stress on metabolic, inflammatory, and behavioral profiles in a mouse model of diet-induced obesity, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry on mouse samples at 7 ug/ml (tbl s5) and in western blot on mouse samples at 3 ug/ml (tbl s5). Brain Behav Immun (2017) ncbi
domestic rabbit polyclonal (MH44)
  • western blot; dogs; 1:1000
In order to investigate how serine proteases increase transepithelial electrical resistance, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in western blot on dogs samples at 1:1000. Am J Physiol Gastrointest Liver Physiol (2016) ncbi
mouse monoclonal (12H12)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to evaluate the effect of glucocorticoids in a mouse model of colitis, Invitrogen claudin 2 antibody (Thermo Fisher, 32-5600) was used in western blot on mouse samples at 1:1000 (fig 3a). Biochem Pharmacol (2016) ncbi
mouse monoclonal (12H12)
  • western blot; rhesus macaque; 2 ug/ml; loading ...; fig 9b
In order to study a nonhuman primate model of chronic gastrointestinal syndrome, Invitrogen claudin 2 antibody (Invitrogen, 325600) was used in western blot on rhesus macaque samples at 2 ug/ml (fig 9b). Radiat Res (2016) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 7
In order to study the favored formation of polarized salivary acinar-like structures by the role of human fibronectin- or placenta basement membrane extract-based gels, Invitrogen claudin 2 antibody (Zymed, 51-6100) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 7). J Tissue Eng Regen Med (2017) ncbi
mouse monoclonal (12H12)
  • western blot; domestic goat; 1:1000; fig 3
In order to characterize a reduced N and/or Ca diet by expression of tight junction proteins and cadherin 17 in the small intestine of young goats, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in western blot on domestic goat samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi
domestic rabbit polyclonal (MH44)
  • immunohistochemistry - paraffin section; domestic horse; fig 3
  • western blot; domestic horse; 1:1000; fig 1
In order to compare expression levels and distribution of Claudin-1, 2, 4, and 5 in equine tissues, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used in immunohistochemistry - paraffin section on domestic horse samples (fig 3) and in western blot on domestic horse samples at 1:1000 (fig 1). J Vet Sci (2016) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; mouse; fig 1
In order to utilize a microwave antigen retrieval method by using two heating steps for enhanced immunostaining on tissue sections that are aldehyde-fixed and paraffin-embedded, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry - paraffin section on mouse samples (fig 1). Histochem Cell Biol (2016) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; mouse; fig 3
In order to study a reconstituted choroid plexus epithelium to show T-lymphocytes traffic into the brain across the blood-CSF barrier, Invitrogen claudin 2 antibody (Life Technologies, 51-6100) was used in immunocytochemistry on mouse samples (fig 3). PLoS ONE (2016) ncbi
domestic rabbit polyclonal (MH44)
  • immunocytochemistry; mouse; 10 ug/ml; fig 2
In order to study a model of immune functions of the mouse blood-cerebrospinal fluid barrier in vitro using primary epithelial cells better suited to study immune cell migration across the brain barrier, Invitrogen claudin 2 antibody (Invitrogen, 516100) was used in immunocytochemistry on mouse samples at 10 ug/ml (fig 2). Fluids Barriers CNS (2016) ncbi
domestic rabbit polyclonal (MH44)
  • western blot; human; fig 2
In order to describe a method to identify host RNA-binding proteins during Dengue virus infection, Invitrogen claudin 2 antibody (Life Technologies, 51-6100) was used in western blot on human samples (fig 2). MBio (2016) ncbi
mouse monoclonal (12H12)
  • western blot; human
In order to study OGR1-mediated, pH-dependent signaling pathways in intestinal epithelial cells, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in western blot on human samples . Am J Physiol Gastrointest Liver Physiol (2015) ncbi
domestic rabbit polyclonal (MH44)
In order to test if urinary fluid shear stress alters the epithelial characteristics of the renal tubule, Invitrogen claudin 2 antibody (Invitrogen, 51-C6100) was used . PLoS ONE (2015) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs; fig 3g
  • western blot; dogs; fig 3f
In order to investigate the interaction between ZO-1 and TOCA-1, Invitrogen claudin 2 antibody (Life Technologies, 32-5600) was used in immunocytochemistry on dogs samples (fig 3g) and in western blot on dogs samples (fig 3f). Mol Biol Cell (2015) ncbi
domestic rabbit polyclonal (MH44)
In order to study the effects of TNF exposure on tight junction proteins using LLC-PK1 tubular cells, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used . Am J Physiol Cell Physiol (2015) ncbi
domestic rabbit polyclonal (MH44)
In order to investigate the role of claudin-1/claudin-5 in epithelial/endothelial barriers, Invitrogen claudin 2 antibody (Life Technologies, 51-6100) was used . Biomaterials (2015) ncbi
mouse monoclonal (12H12)
  • western blot; human; 0.1 ug/ml; fig 1
  • western blot; mouse; 0.1 ug/ml; fig 1
In order to analyze breast cancer liver metastasis and how Lyn modulates Claudin-2 expression as a therapeutic target, Invitrogen claudin 2 antibody (Invitrogen, 325600) was used in western blot on human samples at 0.1 ug/ml (fig 1) and in western blot on mouse samples at 0.1 ug/ml (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry; rat; 1:2000; fig 9
In order to examine the mast cell proteinase and tight junction protein kinetics in a rat model of post-infectious gut dysfunction, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry on rat samples at 1:2000 (fig 9). J Crohns Colitis (2015) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs
  • western blot; dogs
In order to characterize TALEN-mediated claudin-2 knockout in MDCK cells, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunocytochemistry on dogs samples and in western blot on dogs samples . PLoS ONE (2015) ncbi
mouse monoclonal (12H12)
  • western blot; human
In order to investigate the effect of homoharringtonine on intestinal epithelial permeability and its mechanism, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in western blot on human samples . Eur J Pharm Biopharm (2015) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry; human; 1:100; fig 1
In order to correlate expression of claudins with clinical outcomes of triple-negative breast cancer, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry on human samples at 1:100 (fig 1). PLoS ONE (2014) ncbi
domestic rabbit polyclonal (MH44)
In order to study tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery, Invitrogen claudin 2 antibody (Invitrogen, 51-6100) was used . Surg Obes Relat Dis (2015) ncbi
mouse monoclonal (12H12)
  • flow cytometry; human
In order to perform longitudinal and cross-sectional studies of patients after restorative proctocolectomy and assess tight junction proteins and dendritic cell characteristics in the ileal pouch, Invitrogen claudin 2 antibody (Invitrogen, 12H12) was used in flow cytometry on human samples . Inflamm Bowel Dis (2014) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs
  • western blot; dogs
In order to characterize the TALEN-mediated ZO-1 knockout in MDCK cells, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunocytochemistry on dogs samples and in western blot on dogs samples . PLoS ONE (2014) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; human; fig 3
In order to assess the role of Toll-like receptor 2 in maintaining the integrity of the airway epithelial barrier, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunocytochemistry on human samples (fig 3). Tissue Barriers (2014) ncbi
mouse monoclonal (12H12)
  • western blot; human
In order to investigate the localization of POF1B in desmosomes and its role in human intestinal and keratinocyte cell lines, Invitrogen claudin 2 antibody (Zymed Laboratories, 32-5600) was used in western blot on human samples . J Invest Dermatol (2015) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1b
In order to correlate claudin 1-5 and 7 expression with the survival, grade, and stage of patients with renal cell cancer, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples (fig 1b). Anticancer Res (2014) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; human; 1:100; fig 4
In order to assess the contribution of enteropathogenic Escherichia coli EspG-mediated microtubule disruption to tight junction perturbation, Invitrogen claudin 2 antibody (Life Technologies, 325600) was used in immunocytochemistry on human samples at 1:100 (fig 4). Cell Microbiol (2014) ncbi
mouse monoclonal (12H12)
  • western blot; mouse; loading ...; fig 6b
In order to study the role of TH9 cells in ulcerative colitis, Invitrogen claudin 2 antibody (Invitrogen, 12H12) was used in western blot on mouse samples (fig 6b). Nat Immunol (2014) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; human; 1:300
  • western blot; human; 1:500
In order to evaluate claudin 2 as a proximal tubular stress responsive paracellular water channel, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on human samples at 1:300 and in western blot on human samples at 1:500. Toxicol Appl Pharmacol (2014) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry; human
  • western blot; human; 1:5000
In order to study the involvement of TJP2 mautations in progressive cholestatic liver disease, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry on human samples and in western blot on human samples at 1:5000. Nat Genet (2014) ncbi
domestic rabbit polyclonal (MH44)
In order to determine the quantity, distribution and function of tight junction proteins in patients undergoing dialysis treatments, Invitrogen claudin 2 antibody (Zymed, 51-6100) was used . Perit Dial Int (2015) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; human; fig 3
  • western blot; human; 0.8 ug/ml; fig 3
In order to study the molecular processes involved in renal epithelial proximal-tubule monolayer maturation, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples at 0.8 ug/ml (fig 3). Mol Cell Biol (2013) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human
  • immunohistochemistry - frozen section; mouse; 2.5 ug/ml; fig 4
  • western blot; mouse
In order to study the effects of intestinal barrier proteins in necrotizing enterocolitis and test if Bifidobacterium infantis modulates tight junction proteins, Invitrogen claudin 2 antibody (Life Technologies, 32-5600) was used in immunohistochemistry - paraffin section on human samples , in immunohistochemistry - frozen section on mouse samples at 2.5 ug/ml (fig 4) and in western blot on mouse samples . Am J Pathol (2013) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - frozen section; mouse; fig 3
In order to examine innate responses to Entamoeba histolytica in wild-type and MUC-2-deficient mice, Invitrogen claudin 2 antibody (Invitrogen, 325600) was used in immunohistochemistry - frozen section on mouse samples (fig 3). Am J Pathol (2013) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to examine tight junction and adherens junction proteins in normal human lung, IPF, cryptogenic organizing pneumonia, and asbestosis, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Hum Pathol (2013) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - frozen section; human; 1:100; fig 2
  • western blot; human; fig 2
In order to identify genetic variants associated with pancreatitis, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 2) and in western blot on human samples (fig 2). Nat Genet (2012) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - frozen section; mouse; 1:250; fig 4
  • immunoprecipitation; mouse; fig 2
  • western blot; mouse; 1:500; fig 2
In order to report that mice lacking EpCAM have intestinal barrier defects and die shortly after birth as a result of intestinal erosion, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4), in immunoprecipitation on mouse samples (fig 2) and in western blot on mouse samples at 1:500 (fig 2). Dev Biol (2012) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; human; 1:300; fig 4
  • western blot; human; 1:600; fig 6
In order to determine the effects of KBrO(3) using human and rat proximal tubular cell lines, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on human samples at 1:300 (fig 4) and in western blot on human samples at 1:600 (fig 6). Arch Toxicol (2012) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - frozen section; human; 1:100
  • western blot; human; 1:1000; fig 2
In order to assess the role of tight junctions and gap proteins in cervical remodeling, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunohistochemistry - frozen section on human samples at 1:100 and in western blot on human samples at 1:1000 (fig 2). J Transl Med (2012) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs; fig 1
  • western blot; dogs; fig 2, 4
In order to examine the effect of treating epithelial cells with an inhibitor of the lipid kinase PIKfyve, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on dogs samples (fig 1) and in western blot on dogs samples (fig 2, 4). PLoS ONE (2012) ncbi
mouse monoclonal (12H12)
  • western blot; dogs; fig 1
In order to analyze the role of paracingulin domains, Invitrogen claudin 2 antibody (Invitrogen, 32-5600) was used in western blot on dogs samples (fig 1). J Biol Chem (2012) ncbi
mouse monoclonal (12H12)
  • flow cytometry; mouse; fig 3
  • western blot; mouse; fig s1
In order to identify Cldn1, Cldn2 and Cldn11 as genes that discriminate between diverse types of M2, Invitrogen claudin 2 antibody (Invitrogen, 12H12) was used in flow cytometry on mouse samples (fig 3) and in western blot on mouse samples (fig s1). Scand J Immunol (2012) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs; 1:25; fig s7
In order to demonstrate that ESCRT proteins are required to maintain polarity in mammalian epithelial cells, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on dogs samples at 1:25 (fig s7). Mol Biol Cell (2011) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; fig 3
In order to determine claudin expression profiles in Epstein-Barr virus-associated non-keratinizing nasopharyngeal carcinoma, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples (fig 3). Oncol Rep (2010) ncbi
mouse monoclonal (12H12)
  • western blot; mouse; 1:100; fig 10
In order to examine the consequences of HNF-4alpha loss in the adult intestinal epithelium, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in western blot on mouse samples at 1:100 (fig 10). Mol Cell Biol (2009) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; rat; 1:100; tbl 3
In order to study the role of claudin-2 in bile canalicular formation, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunocytochemistry on rat samples at 1:100 (tbl 3). Histochem Cell Biol (2009) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
In order to determine the expression of several different claudins in rectal well-differentiated endocrine neoplasms, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). Oncol Rep (2009) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1b
In order to report the expression of various claudins in patients with sarcoidosis, usual interstitial pneumonia, and normal human lung, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples (fig 1b). J Histochem Cytochem (2009) ncbi
mouse monoclonal (12H12)
  • western blot; human; fig 1
In order to elucidate how the keratin intermediate filament network is involved in the establishment and maintenance of cell polarity, Invitrogen claudin 2 antibody (Invitrogen, 12H12) was used in western blot on human samples (fig 1). J Cell Biol (2008) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; fig 1
In order to test if altered expression of intestinal epithelial tight junction proteins contributes to neoplastic progression, Invitrogen claudin 2 antibody (Invitrogen, 12H12) was used in immunohistochemistry - paraffin section on human samples (fig 1). Lab Invest (2008) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
In order to study the role of CLDN2 expression in breast cancer development and progression, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3). Histopathology (2008) ncbi
mouse monoclonal (12H12)
  • western blot; dogs; fig 3
In order to study the effects of cingulin overexpression, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in western blot on dogs samples (fig 3). Mol Membr Biol (2008) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; rat; 1:100; fig 2B
In order to determine whether transforming growth factor-beta down-regulates claudin-1 expression to induce epithelial to mesenchymal transition, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunocytochemistry on rat samples at 1:100 (fig 2B). Liver Int (2008) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; 1:400; fig 4
In order to correlate glutamine synthetase immunostaining and beta-catenin mutations with clinicopathological features in hepatocellular carcinomas, Invitrogen claudin 2 antibody (Zymed, clone 12H12) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 4). J Pathol (2007) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; dogs; fig 4
  • western blot; dogs; fig 1
In order to investigate the function of cingulin in tight junctions, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on dogs samples (fig 4) and in western blot on dogs samples (fig 1). Mol Biol Cell (2006) ncbi
mouse monoclonal (12H12)
  • immunohistochemistry - paraffin section; human; 1:50
In order to observe the expression of claudins in mesothelioma and metastatic pleural adenocarcinoma, Invitrogen claudin 2 antibody (Zymed, 12H12) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Clin Pathol (2006) ncbi
mouse monoclonal (12H12)
  • immunocytochemistry; rat
  • immunocytochemistry; pigs
  • immunocytochemistry; human
  • immunocytochemistry; American opossums
In order to characterize cell lines that mimic the characteristics of the proximal tubule, Invitrogen claudin 2 antibody (Zymed, 32-5600) was used in immunocytochemistry on rat samples , in immunocytochemistry on pigs samples , in immunocytochemistry on human samples and in immunocytochemistry on American opossums samples . Toxicol In Vitro (2006) ncbi
Articles Reviewed
  1. Tabariès S, Annis M, Lazaris A, Petrillo S, Huxham J, Abdellatif A, et al. Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern. Commun Biol. 2021;4:657 pubmed publisher
  2. Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al. Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. Am J Physiol Gastrointest Liver Physiol. 2021;320:G936-G957 pubmed publisher
  3. Cox C, Lu R, Salcin K, Wilson J. The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation. Cell Mol Gastroenterol Hepatol. 2018;5:145-156 pubmed publisher
  4. Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed publisher
  5. Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  6. Zhang C, Yan J, Xiao Y, Shen Y, Wang J, Ge W, et al. Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers. Int J Mol Sci. 2017;18: pubmed publisher
  7. Torres Martínez A, Gallardo Vera J, Lara Holguin A, Montano L, Rendón Huerta E. Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells. Exp Cell Res. 2017;350:226-235 pubmed publisher
  8. Lepage D, Bélanger É, Jones C, Tremblay S, Allaire J, Bruneau J, et al. Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury. Sci Rep. 2016;6:36776 pubmed publisher
  9. Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
  10. Ahn C, Shin D, Lee D, Kang S, Seok J, Kang H, et al. Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs. Mol Med Rep. 2016;14:3697-703 pubmed publisher
  11. Randall K, Henderson N, Reens J, Eckersley S, Nyström A, South M, et al. Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies. PLoS ONE. 2016;11:e0162076 pubmed publisher
  12. de Sousa Rodrigues M, Bekhbat M, Houser M, Chang J, Walker D, Jones D, et al. Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain Behav Immun. 2017;59:158-172 pubmed publisher
  13. Ronaghan N, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, et al. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. Am J Physiol Gastrointest Liver Physiol. 2016;311:G466-79 pubmed publisher
  14. Ocón B, Aranda C, Gámez Belmonte R, Suárez M, Zarzuelo A, Martinez Augustin O, et al. The glucocorticoid budesonide has protective and deleterious effects in experimental colitis in mice. Biochem Pharmacol. 2016;116:73-88 pubmed publisher
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