This is a Validated Antibody Database (VAD) review about dogs CFL1, based on 36 published articles (read how Labome selects the articles), using CFL1 antibody in all methods. It is aimed to help Labome visitors find the most suited CFL1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3a
In order to research the role of BAF53b mutations in intellectual disabilities and cognitive disorders, Abcam CFL1 antibody (Abcam, Ab12866) was used in immunohistochemistry on mouse samples at 1:500 (fig 3a). Learn Mem (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
In order to find that frictional force characteristic of flow in the lymphatics stimulates YAP1 to drive cancer cell migration, Abcam CFL1 antibody (Abcam, ab12866) was used in western blot on human samples (fig 4d). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig s9
In order to determine regulation of spine structural plasticity and memory and learning by the calcium sensor Copine-6, Abcam CFL1 antibody (Abcam, ab11062) was used in western blot on mouse samples at 1:1000 (fig s9). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:800; fig 4
  • western blot; rat; 1:8000; fig 1
In order to investigate the temporally associated cessation of growth in the developing hippocampus by cofilin activation, Abcam CFL1 antibody (Abcam, Ab12866) was used in immunocytochemistry on rat samples at 1:800 (fig 4) and in western blot on rat samples at 1:8000 (fig 1). Cereb Cortex (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology CFL1 antibody (Cell Signaling, 51755) was used in western blot on mouse samples (fig 6a). Mol Brain (2021) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; loading ...; fig 7e
Cell Signaling Technology CFL1 antibody (CST, 5175) was used in western blot on human samples at 1:1000 (fig 7e). Oncogene (2021) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:10,000; loading ...; fig s3-2b
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on mouse samples at 1:10,000 (fig s3-2b). elife (2021) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:2000; loading ...; fig 1b
Cell Signaling Technology CFL1 antibody (Cell signaling, D3F9) was used in western blot on mouse samples at 1:2000 (fig 1b). Front Immunol (2020) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; loading ...; fig 5
Cell Signaling Technology CFL1 antibody (cell signalling technology, 5175) was used in western blot on human samples at 1:1000 (fig 5). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; loading ...; fig 4s2h
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples at 1:1000 (fig 4s2h). elife (2019) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:10,000; loading ...
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples at 1:10,000. Nat Med (2019) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; loading ...; fig 5e
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:1000 (fig 5e). J Exp Med (2018) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; loading ...; fig 4j
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples at 1:1000 (fig 4j). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:50; fig 5b
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:50 (fig 5b). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology CFL1 antibody (CST, 5175) was used in western blot on mouse samples (fig 5b). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; loading ...; fig 3g
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:1000 (fig 3g). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D3F9)
  • flow cytometry; human; loading ...; fig 4c
In order to suggest that persistent immune activation causes impairment of lymphocytes to respond to chemotactic stimuli, preventing their trafficking from the blood stream to peripheral organs, Cell Signaling Technology CFL1 antibody (Cell Signaling, D3F9) was used in flow cytometry on human samples (fig 4c). J Immunol (2017) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 9a
In order to explore the role of CAP2 in the brain, Cell Signaling Technology CFL1 antibody (Cell signaling, D3F9) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8c) and in western blot on mouse samples at 1:1000 (fig 9a). Front Cell Neurosci (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
  • western blot; human; 1:700; loading ...; fig 3c
In order to study the contribution of cofilin in osteoblastic mechanotransduction, Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in immunocytochemistry on human samples at 1:100 (fig 2e) and in western blot on human samples at 1:700 (fig 3c). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; fig 7
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples (fig 7). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; fig s2
In order to determine how inhibition of human glioblastoma invasion by actin polymerization can occur by an anti-depressant called fluvoxamine, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples (fig s2). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:2000; fig 1
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175P) was used in western blot on mouse samples at 1:2000 (fig 1). J Cell Biol (2016) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; fig 3
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on mouse samples (fig 3). Front Immunol (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; fig 4
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; fig s2
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on human samples (fig s2). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; human; fig s4
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on human samples (fig s4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • immunoprecipitation; human; fig 6
  • immunocytochemistry; human; fig 6
  • western blot; human; fig 6
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175P) was used in immunoprecipitation on human samples (fig 6), in immunocytochemistry on human samples (fig 6) and in western blot on human samples (fig 6). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology CFL1 antibody (CST, 5175) was used in western blot on mouse samples (fig 3a). Cell Death Differ (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; rat; 1:1000
In order to study the temporal and spatial relationship between dendritic protein synthesis and actin cytoskeleton reorganization, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, #5175) was used in western blot on rat samples at 1:1000. J Neurosci (2015) ncbi
domestic rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000
In order to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, #5175) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
domestic rabbit monoclonal (D3F9)
  • chromatin immunoprecipitation; human
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175S) was used in chromatin immunoprecipitation on human samples . Mol Cancer Res (2014) ncbi
domestic rabbit monoclonal (D3F9)
  • immunohistochemistry - paraffin section; human; 1:400
  • immunocytochemistry; human; 1:1000; fig 4
  • western blot; human; 1:1000
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in immunohistochemistry - paraffin section on human samples at 1:400, in immunocytochemistry on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:1000. PLoS ONE (2012) ncbi
BD Biosciences
mouse monoclonal (32/Cofilin)
  • western blot; human; fig 2
In order to study a novel compound via preclinical validation that targets p70SR kinase in breast cancer, BD Biosciences CFL1 antibody (BD Biosciences, 612145) was used in western blot on human samples (fig 2). Aging (Albany NY) (2016) ncbi
mouse monoclonal (32/Cofilin)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences CFL1 antibody (BD, 32) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Articles Reviewed
  1. Zhang H, Ben Zablah Y, Liu A, Lee D, Zhang H, Meng Y, et al. Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice. Mol Brain. 2021;14:121 pubmed publisher
  2. Qiao Y, Jin T, Guan S, Cheng S, Wen S, Zeng H, et al. Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1. Oncogene. 2021;40:4198-4213 pubmed publisher
  3. Renteria R, Cazares C, Baltz E, Schreiner D, Yalcinbas E, Steinkellner T, et al. Mechanism for differential recruitment of orbitostriatal transmission during actions and outcomes following chronic alcohol exposure. elife. 2021;10: pubmed publisher
  4. Märklin M, Fuchs A, Tandler C, Heitmann J, Salih H, Kauer J, et al. Genetic Loss of LCK Kinase Leads to Acceleration of Chronic Lymphocytic Leukemia. Front Immunol. 2020;11:1995 pubmed publisher
  5. Inda M, Joshi S, Wang T, Bolaender A, Gandu S, Koren Iii J, et al. The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction. Nat Commun. 2020;11:319 pubmed publisher
  6. Zeng H, Castillo Cabrera J, Manser M, Lu B, Yang Z, Strande V, et al. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC. elife. 2019;8: pubmed publisher
  7. Sharifnia T, Wawer M, Chen T, Huang Q, Weir B, Sizemore A, et al. Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nat Med. 2019;25:292-300 pubmed publisher
  8. Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed publisher
  9. Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
  10. Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher
  11. Vogel Ciernia A, Kramár E, Matheos D, Havekes R, Hemstedt T, Magnan C, et al. Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling. Learn Mem. 2017;24:199-209 pubmed publisher
  12. Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher
  13. Lee H, Diaz M, Price K, Ozuna J, Zhang S, Sevick Muraca E, et al. Fluid shear stress activates YAP1 to promote cancer cell motility. Nat Commun. 2017;8:14122 pubmed publisher
  14. Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed publisher
  15. Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  16. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  17. Kumar A, Paeger L, Kosmas K, Kloppenburg P, Noegel A, Peche V. Neuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2. Front Cell Neurosci. 2016;10:180 pubmed publisher
  18. Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
  19. Gao J, Fu S, Zeng Z, Li F, Niu Q, Jing D, et al. Cyclic stretch promotes osteogenesis-related gene expression in osteoblast-like cells through a cofilin-associated mechanism. Mol Med Rep. 2016;14:218-24 pubmed publisher
  20. Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher
  21. Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher
  22. Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
  23. Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed publisher
  24. Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei F, et al. Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization. Sci Rep. 2016;6:23372 pubmed publisher
  25. Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed publisher
  26. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  27. Lu K, Tounsi A, Shridhar N, Küblbeck G, Klevenz A, Prokosch S, et al. Dickkopf-3 Contributes to the Regulation of Anti-Tumor Immune Responses by Mesenchymal Stem Cells. Front Immunol. 2015;6:645 pubmed publisher
  28. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  29. Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed publisher
  30. Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed publisher
  31. Dugina V, Khromova N, Rybko V, Blizniukov O, Shagieva G, Chaponnier C, et al. Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget. 2015;6:14556-71 pubmed
  32. Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
  33. Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
  34. Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed publisher
  35. Madak Erdogan Z, Ventrella R, Petry L, Katzenellenbogen B. Novel roles for ERK5 and cofilin as critical mediators linking ER?-driven transcription, actin reorganization, and invasiveness in breast cancer. Mol Cancer Res. 2014;12:714-27 pubmed publisher
  36. Polachini G, Sobral L, Mercante A, Paes Leme A, Xavier F, Henrique T, et al. Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis. PLoS ONE. 2012;7:e50517 pubmed publisher