This is a Validated Antibody Database (VAD) review about dogs CDKN1B, based on 60 published articles (read how Labome selects the articles), using CDKN1B antibody in all methods. It is aimed to help Labome visitors find the most suited CDKN1B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDKN1B synonym: Kip1; p27; p27Kip1

Knockout validation
BD Biosciences
mouse monoclonal (57/Kip1/p27)
  • western blot knockout validation; brown rat; 1:1000; loading ...; fig s1d
BD Biosciences CDKN1B antibody (BD, 610241) was used in western blot knockout validation on brown rat samples at 1:1000 (fig s1d). PLoS Genet (2019) ncbi
BD Biosciences
mouse monoclonal (57/Kip1/p27)
  • western blot knockout validation; mouse; fig 2
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot knockout validation on mouse samples (fig 2). Nucleic Acids Res (2015) ncbi
Invitrogen
mouse monoclonal (DCS-72.F6)
  • immunohistochemistry; mouse; 1:100; fig 5b
Invitrogen CDKN1B antibody (NeoMarkers, MS-256-P1) was used in immunohistochemistry on mouse samples at 1:100 (fig 5b). Nat Commun (2017) ncbi
mouse monoclonal (DCS-72.F6)
  • western blot; human; 1:500; fig 2
In order to elucidate the affect of p38 MAPK-mediated regulation of NB69 cell proliferation implication of free radicals by power frequency magnetic fields, Invitrogen CDKN1B antibody (BioSource, AHZ0452) was used in western blot on human samples at 1:500 (fig 2). Int J Mol Sci (2016) ncbi
mouse monoclonal (DCS-72.F6)
  • immunocytochemistry; mouse; 1:200; fig 5
In order to analyze promotion of inner ear hair cells in mouse embryonic stem cells in vitro, Invitrogen CDKN1B antibody (Biosource, AHZ0452) was used in immunocytochemistry on mouse samples at 1:200 (fig 5). Methods Mol Biol (2016) ncbi
mouse monoclonal (DCS-72.F6)
  • immunohistochemistry; mouse; 1:200
In order to elucidate the molecular mechanisms involved in the timing and coordination of auditory prosensory proliferation and differentiation, Invitrogen CDKN1B antibody (NeoMarkers/Thermo, MS-256-P1) was used in immunohistochemistry on mouse samples at 1:200. Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (DCS-72.F6)
  • western blot; human; 1:200
In order to study kinases involved in H2AX phosphorylation in irradiated human keratinocytes, Invitrogen CDKN1B antibody (Invitrogen, AHZ0452) was used in western blot on human samples at 1:200. Cell Mol Life Sci (2015) ncbi
mouse monoclonal (DCS-72.F6)
  • western blot; mouse; fig 1
In order to explore the contributions of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration, Invitrogen CDKN1B antibody (Thermo Fisher Scientific, DCS-72.F6) was used in western blot on mouse samples (fig 1). Int J Endocrinol (2012) ncbi
mouse monoclonal (DCS-72.F6)
  • immunohistochemistry - paraffin section; human; 1:40
In order to identify diagnostic and prognostic markers for glioblastoma, Invitrogen CDKN1B antibody (Lab Vision, MS-256) was used in immunohistochemistry - paraffin section on human samples at 1:40. Int J Oncol (2012) ncbi
mouse monoclonal (DCS-72.F6)
  • immunohistochemistry - paraffin section; mouse; fig 2
In order to determine the role of Shp2 in brain development, Invitrogen CDKN1B antibody (Biosource, AHZ0452) was used in immunohistochemistry - paraffin section on mouse samples (fig 2). Dev Biol (2009) ncbi
mouse monoclonal (DCS-72.F6)
  • immunoprecipitation; American mink
  • western blot; American mink
In order to study if the growth state-dependent tyrosine phosphorylation of p27Kip1 determines whether or not it inhibits cdk4, Invitrogen CDKN1B antibody (NeoMarkers, DCS-72.F6) was used in immunoprecipitation on American mink samples and in western blot on American mink samples . Mol Cell Biol (2008) ncbi
mouse monoclonal (DCS-72.F6)
  • western blot; human; fig 7
In order to elucidate how PTEN reduces proliferation without cell cycle arrest in T cells, Invitrogen CDKN1B antibody (Biosource, DCS-72.F6) was used in western blot on human samples (fig 7). Oncogene (2003) ncbi
Abcam
mouse monoclonal (SX53G8)
  • western blot; human; loading ...; fig 5a
Abcam CDKN1B antibody (Abcam, ab193379) was used in western blot on human samples (fig 5a). J Mol Neurosci (2018) ncbi
BD Biosciences
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3b
BD Biosciences CDKN1B antibody (BD Pharmingen, 610241) was used in immunohistochemistry on mouse samples at 1:500 (fig 3b). elife (2019) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot knockout validation; brown rat; 1:1000; loading ...; fig s1d
BD Biosciences CDKN1B antibody (BD, 610241) was used in western blot knockout validation on brown rat samples at 1:1000 (fig s1d). PLoS Genet (2019) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry; mouse; loading ...; fig 2c
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in immunohistochemistry on mouse samples (fig 2c). J Neurosci (2019) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; loading ...; fig 2c
BD Biosciences CDKN1B antibody (BD, 610241) was used in western blot on human samples (fig 2c). J Biol Chem (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1d
  • immunocytochemistry; mouse; 1:500; fig s8b
In order to explore the role of chromodomain helicase DNA-binding protein 7 in CHARGE syndrome, BD Biosciences CDKN1B antibody (BD bioscience, 610241) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 1d) and in immunocytochemistry on mouse samples at 1:500 (fig s8b). Nat Commun (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; loading ...; fig 1d
BD Biosciences CDKN1B antibody (BD Biosciences, 616242) was used in western blot on human samples (fig 1d). Mol Cancer Ther (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 2h
BD Biosciences CDKN1B antibody (BD Biosciences, 610242) was used in western blot on human samples (fig 2h). Nat Med (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...
In order to propose a tumor-suppressive activity for macrophage migration inhibitory factor in murine skin, BD Biosciences CDKN1B antibody (Becton Dickinson, 57) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. FASEB J (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; 1:500; loading ...; fig 9a
In order to report the effects of valproic acid exposure in utero, BD Biosciences CDKN1B antibody (Becton Dickinson, 610241) was used in western blot on mouse samples at 1:500 (fig 9a). J Neurosci (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:1000; loading ...; fig 3d
In order to elucidate the contribution of MDM2 expression to retinoblastoma tumorigenesis, BD Biosciences CDKN1B antibody (Becton Dickenson, 610241) was used in western blot on human samples at 1:1000 (fig 3d). Oncogene (2017) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 0.5 ug/ml; loading ...; fig 3B
BD Biosciences CDKN1B antibody (BD, 610242) was used in western blot on human samples at 0.5 ug/ml (fig 3B). J Cell Biol (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; loading ...; fig 2k
In order to demonstrate that cyclin A2 regulates erythrocyte morphology and numbers, BD Biosciences CDKN1B antibody (BD Transduction, 610242) was used in western blot on mouse samples (fig 2k). Cell Cycle (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:2000; loading ...; fig 2c
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on human samples at 1:2000 (fig 2c). Oncotarget (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - paraffin section; human; 1:1000; tbl 3
In order to investigate evidence for two distinct pathogenetic pathways by studing the squamous cell carcinoma of the oral cavity and cytokeratin and protein expression patterns, BD Biosciences CDKN1B antibody (BD TL, 610241) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (tbl 3). Oncol Lett (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 5
In order to assess regulation of the small muscle protein, X-linked (SMPX) and myotube differentiation by the nuclear receptor NOR-1, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 5
BD Biosciences CDKN1B antibody (BD, 610242) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; 1:1000; loading ...; fig 6e
In order to show that Rb1 and Skp2 deletions are synthetic lethal and explore how this lethal relationship can be circumvented, BD Biosciences CDKN1B antibody (BD Transduction Lab, 610242) was used in western blot on mouse samples at 1:1000 (fig 6e). J Biol Chem (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:1000; fig 1
In order to investigate activation of APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth by TGF-beta, BD Biosciences CDKN1B antibody (BD Biosciences, BDB610242) was used in western blot on human samples at 1:1000 (fig 1). Cell Cycle (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 6
In order to characterize multiple molecularly defined cancer indications by studying ROS1, ALK inhibitor, Entrectinib, a Pan-TRK activity, BD Biosciences CDKN1B antibody (BD Biosciences, 610242) was used in western blot on human samples (fig 6). Mol Cancer Ther (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 1
In order to investigate proteolytic processing of p27, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig S1B
BD Biosciences CDKN1B antibody (BD, 610241) was used in western blot on human samples (fig S1B). PLoS ONE (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:2000; fig 4
  • immunohistochemistry - frozen section; mouse; fig 1
  • western blot; mouse; 1:2000; fig 1
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on human samples at 1:2000 (fig 4), in immunohistochemistry - frozen section on mouse samples (fig 1) and in western blot on mouse samples at 1:2000 (fig 1). FASEB J (2016) ncbi
mouse monoclonal (57/Kip1/p27)
  • chromatin immunoprecipitation; human; fig 4
  • western blot; human; 1:1000; fig 1
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in chromatin immunoprecipitation on human samples (fig 4) and in western blot on human samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human
In order to study the effect of neddylation on COP9-Signalosome deneddylase activity, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot on human samples . Cell Div (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:500; fig 1
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on human samples at 1:500 (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot knockout validation; mouse; fig 2
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot knockout validation on mouse samples (fig 2). Nucleic Acids Res (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
In order to develop a CRISPR/Cas9-mediated method for somatic gene disruption, BD Biosciences CDKN1B antibody (BD Biosciences, 610242) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 1
BD Biosciences CDKN1B antibody (BD bioscience, 610241) was used in western blot on human samples (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:1000
In order to study the contribution of the Skp2-mH2A1-CDK8 axis to breast cancer, BD Biosciences CDKN1B antibody (InBD Transduction Lab, 610241) was used in western blot on human samples at 1:1000. Nat Commun (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 2
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on human samples (fig 2). Pigment Cell Melanoma Res (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry; mouse; 1:300
In order to investigate the role of Fgf10 in the development of the vertebrate inner ear, BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in immunohistochemistry on mouse samples at 1:300. Dev Biol (2015) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse
In order to identify the mechanistic link between Cullin neddylation and Myc ubiquitination/degradation, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on mouse samples . Nat Commun (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on mouse samples . Mol Cell Biol (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; 1:1000; fig 8
In order to elucidate the molecular mechanisms of dilation formation and nuclear elongation, BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on mouse samples at 1:1000 (fig 8). Development (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610242) was used in western blot on human samples . BMC Cancer (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human
BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; 1:1000
In order to investigate the effect of epidermal growth factor on Skp2/Cks1 and p27kip1 in human extrahepatic cholangiocarcinoma cells, BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on human samples at 1:1000. World J Gastroenterol (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on human samples . Cell Death Differ (2014) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; 1:1000
BD Biosciences CDKN1B antibody (Becton Dickinson, 610242) was used in western blot on mouse samples at 1:1000. Genes Dev (2013) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on mouse samples . Cell Death Differ (2013) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - frozen section; bantam; 1:200
BD Biosciences CDKN1B antibody (BD Transduction Labs, 610241) was used in immunohistochemistry - frozen section on bantam samples at 1:200. PLoS ONE (2013) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human
In order to investigate the effect of cyclin E1 and E2 on genomic instability, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on human samples . Cell Cycle (2013) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - paraffin section; mouse; 0.5 ug/mL
BD Biosciences CDKN1B antibody (BD Transduction, 610242) was used in immunohistochemistry - paraffin section on mouse samples at 0.5 ug/mL. Hum Reprod (2013) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; fig 4
BD Biosciences CDKN1B antibody (BD Transduction, 610242) was used in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2012) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; human; fig 7
BD Biosciences CDKN1B antibody (BD Biosciences, 61041) was used in western blot on human samples (fig 7). Oncogene (2012) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse
In order to study the role in Cdk regulation of the novel gene magoh identified in a genetic screen of a murine cell cycle mutant, BD Biosciences CDKN1B antibody (BD Transduction Laboratories, 610241) was used in western blot on mouse samples . Genes Cells (2011) ncbi
mouse monoclonal (57/Kip1/p27)
  • western blot; mouse; 1:500
BD Biosciences CDKN1B antibody (BD Biosciences, 610241) was used in western blot on mouse samples at 1:500. J Comp Neurol (2010) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry - frozen section; mouse; 1:100
BD Biosciences CDKN1B antibody (BD Transduction Labs, 610241) was used in immunohistochemistry - frozen section on mouse samples at 1:100. J Comp Neurol (2008) ncbi
mouse monoclonal (57/Kip1/p27)
  • immunohistochemistry; mouse; 1:200
BD Biosciences CDKN1B antibody (BD Transduction, 610241) was used in immunohistochemistry on mouse samples at 1:200. J Comp Neurol (2007) ncbi
Articles Reviewed
  1. Lawton A, Engstrom T, Rohrbach D, Omura M, Turnbull D, Mamou J, et al. Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern. elife. 2019;8: pubmed publisher
  2. Ding L, Shunkwiler L, Harper N, Zhao Y, Hinohara K, Huh S, et al. Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment. PLoS Genet. 2019;15:e1008002 pubmed publisher
  3. Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman J, Reddy N, et al. The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain. J Neurosci. 2019;39:44-62 pubmed publisher
  4. Wang J, Wang F, Zhu J, Song M, An J, Li W. Transcriptome Profiling Reveals PHLDA1 as a Novel Molecular Marker for Ischemic Cardiomyopathy. J Mol Neurosci. 2018;65:102-109 pubmed publisher
  5. Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed publisher
  6. Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
  7. Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed publisher
  8. Ishikawa Y, Gamo K, Yabuki M, Takagi S, Toyoshima K, Nakayama K, et al. A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells. Mol Cancer Ther. 2017;16:273-284 pubmed publisher
  9. Cramer S, Saha A, Liu J, Tadi S, Tiziani S, Yan W, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017;23:120-127 pubmed publisher
  10. Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll U, Seegobin S, et al. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. FASEB J. 2017;31:526-543 pubmed publisher
  11. Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, Takahashi T. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation. J Neurosci. 2016;36:10908-10919 pubmed
  12. Qi D, Cobrinik D. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation. Oncogene. 2017;36:1760-1769 pubmed publisher
  13. Uematsu K, Okumura F, Tonogai S, Joo Okumura A, Alemayehu D, Nishikimi A, et al. ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation. J Cell Biol. 2016;215:95-106 pubmed
  14. Jayapal S, Ang H, Wang C, Bisteau X, Caldez M, Xuan G, et al. Cyclin A2 regulates erythrocyte morphology and numbers. Cell Cycle. 2016;15:3070-3081 pubmed
  15. Xue C, Yu D, Gherardi S, Koach J, Milazzo G, Gamble L, et al. MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4. Oncotarget. 2016;7:54937-54951 pubmed publisher
  16. Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
  17. Ferrán B, Martí Pàmies I, Alonso J, Rodríguez Calvo R, Aguiló S, Vidal F, et al. The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation. Sci Rep. 2016;6:25944 pubmed publisher
  18. Martínez M, Ubeda A, Moreno J, Trillo M. Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals. Int J Mol Sci. 2016;17:510 pubmed publisher
  19. Yoshikawa M, Ouji Y. Induction of Inner Ear Hair Cells from Mouse Embryonic Stem Cells In Vitro. Methods Mol Biol. 2016;1516:257-267 pubmed publisher
  20. Cao C, Wang Z, Huang L, Bai L, Wang Y, Liang Y, et al. Down-regulation of tumor endothelial marker 8 suppresses cell proliferation mediated by ERK1/2 activity. Sci Rep. 2016;6:23419 pubmed publisher
  21. Zhao H, Wang H, Bauzon F, Lu Z, Fu H, Cui J, et al. Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. J Biol Chem. 2016;291:10201-9 pubmed publisher
  22. Pavlides S, Lecanda J, Daubriac J, Pandya U, Gama P, Blank S, et al. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth. Cell Cycle. 2016;15:931-47 pubmed publisher
  23. Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  24. Podmirseg S, Jäkel H, Ranches G, Kullmann M, Sohm B, Villunger A, et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene. 2016;35:4580-90 pubmed publisher
  25. Ding X, Jiang W, Zhou P, Liu L, Wan X, Yuan X, et al. Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7). PLoS ONE. 2015;10:e0145023 pubmed publisher
  26. Lyu L, Whitcomb E, Jiang S, Chang M, Gu Y, Duncan M, et al. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. FASEB J. 2016;30:1087-95 pubmed publisher
  27. Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher
  28. Bornstein G, Grossman C. COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex. Cell Div. 2015;10:5 pubmed publisher
  29. Golden E, Benito Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015;112:E3864-73 pubmed publisher
  30. Ge F, Chen W, Qin J, Zhou Z, Liu R, Liu L, et al. Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5). Oncotarget. 2015;6:21369-78 pubmed
  31. Orlando S, Gallastegui E, Besson A, Abril G, Aligué R, Pujol M, et al. p27Kip1 and p21Cip1 collaborate in the regulation of transcription by recruiting cyclin-Cdk complexes on the promoters of target genes. Nucleic Acids Res. 2015;43:6860-73 pubmed publisher
  32. Zuckermann M, Hovestadt V, Knobbe Thomsen C, Zapatka M, Northcott P, Schramm K, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nat Commun. 2015;6:7391 pubmed publisher
  33. Wang C, Nie Z, Zhou Z, Zhang H, Liu R, Wu J, et al. The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1. Oncotarget. 2015;6:17685-97 pubmed
  34. Benzina S, Pitaval A, Lemercier C, Lustremant C, Frouin V, Wu N, et al. A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation. Cell Mol Life Sci. 2015;72:3559-73 pubmed publisher
  35. Xu D, Li C, Zhang X, Gong Z, Chan C, Lee S, et al. Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis. Nat Commun. 2015;6:6641 pubmed publisher
  36. Vogel C, Smit M, Maddalo G, Possik P, Sparidans R, van der Burg S, et al. Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK. Pigment Cell Melanoma Res. 2015;28:307-17 pubmed publisher
  37. Urness L, Wang X, Shibata S, Ohyama T, Mansour S. Fgf10 is required for specification of non-sensory regions of the cochlear epithelium. Dev Biol. 2015;400:59-71 pubmed publisher
  38. Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed publisher
  39. Perry M, Dufour C, Eichner L, Tsang D, Deblois G, Muller W, et al. ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction. Mol Cell Biol. 2014;34:4232-43 pubmed publisher
  40. Nishimura Y, Shikanai M, Hoshino M, Ohshima T, Nabeshima Y, Mizutani K, et al. Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons. Development. 2014;141:3540-50 pubmed publisher
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