This is a Validated Antibody Database (VAD) review about dogs BTK, based on 8 published articles (read how Labome selects the articles), using BTK antibody in all methods. It is aimed to help Labome visitors find the most suited BTK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cell Signaling Technology
domestic rabbit monoclonal (D3H5)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1b
Cell Signaling Technology BTK antibody (Cell Signaling Technology, 8547) was used in immunohistochemistry on mouse samples at 1:200 (fig 1b). Int J Mol Med (2021) ncbi
domestic rabbit monoclonal (D3H5)
  • mass cytometry; human; 1:200; loading ...; fig s2
Cell Signaling Technology BTK antibody (Cell Signaling, D3H5) was used in mass cytometry on human samples at 1:200 (fig s2). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; human; 1:1000; loading ...; fig 3b, 3e
Cell Signaling Technology BTK antibody (Cell Signaling and Technology, D3H5) was used in western blot on human samples at 1:1000 (fig 3b, 3e). Mol Oncol (2020) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; mouse; loading ...; fig s1a
Cell Signaling Technology BTK antibody (Cell Signaling, 8547S) was used in western blot on mouse samples (fig s1a). Oncogene (2019) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; human; loading ...; fig 5d
In order to report that therapeutic antibody-dependent tumor cell killing was FcgammaR-dependent and mediated by macrophages, Cell Signaling Technology BTK antibody (Cell Signalling, 8547) was used in western blot on human samples (fig 5d). Oncogene (2017) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; human; fig 5b
In order to elucidate how hepatitis C virus infection alters B cell proliferation, Cell Signaling Technology BTK antibody (cell signalling technology, 8547) was used in western blot on human samples (fig 5b). Oncogene (2016) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; rat; fig 5
Cell Signaling Technology BTK antibody (Cell Signaling, 8547) was used in western blot on rat samples (fig 5). Nat Chem Biol (2015) ncbi
domestic rabbit monoclonal (D3H5)
  • western blot; mouse; 1:1000; fig 8c
In order to explore a macrophage TLR9-BTK-calcineurin-NFAT signaling pathway involved in impair fungal immunity, Cell Signaling Technology BTK antibody (Cell signaling, 8547) was used in western blot on mouse samples at 1:1000 (fig 8c). EMBO Mol Med (2015) ncbi
Articles Reviewed
  1. Zhao J, Chen J, Li Y, Xia L, Wu Y. Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation. Int J Mol Med. 2021;48: pubmed publisher
  2. West J, Austin E, Rizzi E, Yan L, Tanjore H, Crabtree A, et al. KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models. Int J Mol Sci. 2021;22: pubmed publisher
  3. Thomsen E, Rovsing A, Anderson M, Due H, Huang J, Luo Y, et al. Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma. Mol Oncol. 2020;: pubmed publisher
  4. Das S, Bar Sagi D. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis. Oncogene. 2019;38:3316-3324 pubmed publisher
  5. Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo S, et al. Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene. 2017;36:2366-2376 pubmed publisher
  6. Dai B, Chen A, Corkum C, Peroutka R, Landon A, Houng S, et al. Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. 2016;35:2979-90 pubmed publisher
  7. Bradshaw J, McFarland J, Paavilainen V, Bisconte A, Tam D, Phan V, et al. Prolonged and tunable residence time using reversible covalent kinase inhibitors. Nat Chem Biol. 2015;11:525-31 pubmed publisher
  8. Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher