This is a Validated Antibody Database (VAD) review about dog TJP2, based on 45 published articles (read how Labome selects the articles), using TJP2 antibody in all methods. It is aimed to help Labome visitors find the most suited TJP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TJP2 synonym: ZO-2; tight junction protein ZO-2; zona occludens 2; zona occludens protein 2; zonula occludens protein 2
Knockout validation
Invitrogen rabbit polyclonal |
| In order to visualize the interaction of claudin, ZO-1 and actin in epithelial tight juntions., Invitrogen TJP2 antibody (GE Healthcare, 38-9100) was used in western blot knockout validation on rat samples (fig 4d). Mol Biol Cell (2017) ncbi |
Invitrogen
rabbit polyclonal |
| Invitrogen TJP2 antibody (ThermoFisher, 711400) was used in western blot on human samples at 1:1000 (fig 3s2a). elife (2019) ncbi |
rabbit polyclonal |
| In order to investigate that role of zonula occludens-2 in Rho protein activation and epithelial development, Invitrogen TJP2 antibody (Invitrogen, 711400) was used in proximity ligation assay on dog samples at 1:100, in immunocytochemistry on dog samples at 1:100 (fig 1a) and in western blot on dog samples at 1:1000 (fig 1a). Biochim Biophys Acta Mol Cell Res (2017) ncbi |
rabbit polyclonal |
| In order to visualize the interaction of claudin, ZO-1 and actin in epithelial tight juntions., Invitrogen TJP2 antibody (GE Healthcare, 38-9100) was used in western blot knockout validation on rat samples (fig 4d). Mol Biol Cell (2017) ncbi |
rabbit polyclonal |
| In order to assess induction of renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway due to ZO-2 silencing, Invitrogen TJP2 antibody (Invitrogen, 711400) was used in immunocytochemistry on dog samples (fig 1A). Mol Biol Cell (2016) ncbi |
rabbit polyclonal |
| In order to characterize two clones from triple negative breast MDA-MB-231 cancer cells, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on human samples at 1:50 (fig 2b) and in western blot on human samples at 1:1000 (fig 2a). Exp Cell Res (2015) ncbi |
rabbit polyclonal |
| In order to describe a miRNA-dependent mechanism of Dicer in reestablishing the barrier function of the skin post-wounding, Invitrogen TJP2 antibody (Invitrogen, 38-9,100) was used in immunohistochemistry - frozen section on mouse samples at 1:200. Mol Ther (2015) ncbi |
rabbit polyclonal |
| In order to characterize TALEN-mediated claudin-2 knockout in MDCK cells, Invitrogen TJP2 antibody (Invitrogen, 38-9100) was used in immunocytochemistry on dog samples . PLoS ONE (2015) ncbi |
rabbit polyclonal |
| In order to investigate the effect of homoharringtonine on intestinal epithelial permeability and its mechanism, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in western blot on human samples . Eur J Pharm Biopharm (2015) ncbi |
rabbit polyclonal |
| In order to study the contribution of ZO-1, -2, and -3 on collecting duct cell proliferation, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on mouse samples at 1:500 (fig 3), in western blot on mouse samples at 1:500 (fig 6) and in immunohistochemistry - paraffin section on rat samples at 1:500 (fig 7). Cell Cycle (2014) ncbi |
rabbit polyclonal |
| In order to study the role of down syndrome cell adhesion molecule during mice retina development, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on mouse samples at 1:400. Mol Vis (2014) ncbi |
rabbit polyclonal |
| In order to characterize the TALEN-mediated ZO-1 knockout in MDCK cells, Invitrogen TJP2 antibody (Invitrogen, 38-9100) was used in immunocytochemistry on dog samples and in western blot on dog samples . PLoS ONE (2014) ncbi |
rabbit polyclonal |
| In order to analyze the barrier properties of mouse brain endothelial cells and stabilizing adherens junctions due to heparan sulfate proteoglycan agrin, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunocytochemistry on mouse samples at 1:100 (fig s5). Cell Tissue Res (2014) ncbi |
rabbit polyclonal |
| In order to study the role of ZO proteins in the regulation of transcription factor DbpA/ZONAB, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in western blot on dog samples . J Biol Chem (2014) ncbi |
rabbit polyclonal |
| In order to investigate the expression of the tight junction proteins occludin, claudin-1 and ZO-2 in the epidermis of female mice, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2) and in western blot on mouse samples at 1:1000 (fig 1). Exp Cell Res (2013) ncbi |
rabbit polyclonal |
| In order to study the effect of endotoxemia on the progression of encephalopathy in relation to BBB permeability during acute liver failure, Invitrogen TJP2 antibody (Invitrogen, 38-9100) was used in western blot on mouse samples at 1:1000. Liver Int (2014) ncbi |
rabbit polyclonal |
| In order to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in western blot on human samples at 1:1000. Arch Dermatol Res (2014) ncbi |
mouse monoclonal (3E8D9) |
| In order to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes, Invitrogen TJP2 antibody (Invitrogen, 37-4700) was used in western blot on human samples at 1:1000. Arch Dermatol Res (2014) ncbi |
rabbit polyclonal |
| In order to identify the mechanism for the vascular permeability syndrome and respiratory distress in severe dengue, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on dog samples at 1:100. J Virol (2013) ncbi |
rabbit polyclonal |
| In order to use Isl1-Cre to investigate the roles of Foxa2 in the prechordal plate and ventral endoderm, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on mouse samples at 1:200 (fig 7). Biol Open (2012) ncbi |
rabbit polyclonal |
| In order to assess the relationship between zona occludens-2 and the Wnt/beta-catenin pathway in podocyte injury and proteinuria, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunohistochemistry - free floating section on mouse samples at 1:50 (fig 3). Am J Physiol Renal Physiol (2013) ncbi |
mouse monoclonal (3E8D9) |
| In order to study permeability and tight junctions in endothelial cells derived from human cord blood, Invitrogen TJP2 antibody (Invitrogen, 3E8D9) was used in immunocytochemistry on human samples at 1:250 (fig 7) and in western blot on human samples at 1:1000 (fig 7). Am J Physiol Heart Circ Physiol (2012) ncbi |
rabbit polyclonal |
| In order to determine the expression pattern of selected components involved in the formation of tight junctions in relation to gastroesophageal reflux disease, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on human samples at 1:30 (fig 2). BMC Gastroenterol (2012) ncbi |
rabbit polyclonal |
| In order to investigate the roles of ZO-1 in mouse embryonic stem cells, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunocytochemistry on mouse samples (fig 2). Stem Cells (2012) ncbi |
rabbit polyclonal |
| In order to study the junctional complexes of liver sinusoidal endothelial cells, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on rat samples (fig 5). PLoS ONE (2012) ncbi |
rabbit polyclonal |
| In order to investigate the effect of ouabain on cilia development in epithelial cells, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on dog samples (fig 2e). Proc Natl Acad Sci U S A (2011) ncbi |
rabbit polyclonal |
| In order to assess the effects of stabilizing the blood brain barrier function by therapeutic targeting tight junction proteins for experimental autoimmune encephalomyelitis, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunohistochemistry - frozen section on mouse samples (tbl 1). Acta Neuropathol (2011) ncbi |
rabbit polyclonal |
| In order to elucidate the role of zonula occludens-2 in trophectoderm differentiation and blastocyst formation in hamsters, Invitrogen TJP2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on mouse samples (fig 1). Theriogenology (2011) ncbi |
rabbit polyclonal |
| In order to discuss the mechanisms by which the blood brain barrier and the blood-cerebrospinal fluid barrier are dysregulated during inflammation, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunohistochemistry on mouse samples (fig 4). Antioxid Redox Signal (2011) ncbi |
rabbit polyclonal |
| In order to study the role of CD44 in tight-junction assembly and barrier function, Invitrogen TJP2 antibody (Zymed, 38-9100) was used in immunohistochemistry on mouse samples (fig s2) and in western blot on mouse samples (fig s2). J Invest Dermatol (2011) ncbi |
rabbit polyclonal |
| In order to identify ZASP as a binding partner of ZO-2, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in immunoprecipitation on dog samples (fig 3), in immunocytochemistry on dog samples at 1:100 (fig 4) and in western blot on dog samples at 1:1000 (fig 3). Exp Cell Res (2010) ncbi |
rabbit polyclonal |
| In order to measure the expression of tight junction proteins in the cerebral cortex, cerebellum, and spinal cord of fetuses after maternal treatment with dexamethasone, Invitrogen TJP2 antibody (Zymed, 71-1400) was used in western blot on sheep samples at 1:5000. Am J Physiol Heart Circ Physiol (2010) ncbi |
rabbit polyclonal | In order to examine the architecture of cellular junctions present in blood and lymphatic vessel endothelium in peripheral lymph nodes, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . Eur J Immunol (2008) ncbi | |
mouse monoclonal (3E8D9) |
| In order to describe a cancer stem cell gene-expression signature, Invitrogen TJP2 antibody (Zymed Laboratories, 3E8D9) was used in flow cytometry on human samples (fig 4). Genome Biol (2008) ncbi |
rabbit polyclonal | In order to study the effects of cingulin overexpression, Invitrogen TJP2 antibody (Zymed, 71- 1400) was used . Mol Membr Biol (2008) ncbi | |
mouse monoclonal (3E8D9) |
| In order to investigate the role of zona occludens-2 in the regulation of cyclin D1 transcription, Invitrogen TJP2 antibody (Zymed Laboratories, 37-4700) was used in immunoprecipitation on dog samples . Mol Biol Cell (2007) ncbi |
rabbit polyclonal | In order to investigate the role of zona occludens-2 in the regulation of cyclin D1 transcription, Invitrogen TJP2 antibody (Zymed Laboratories, 71-1400) was used . Mol Biol Cell (2007) ncbi | |
rabbit polyclonal | In order to ascertain the role of ZO-2 in epithelial cells, Invitrogen TJP2 antibody (Zymed Laboratories, 71-1400) was used . Exp Cell Res (2007) ncbi | |
rabbit polyclonal | In order to study the co-association of connexin36, zonula occludens-1, zonula occludens-2, and Y-box transcription factor 3 in mouse and rat retina, Invitrogen TJP2 antibody (Invitrogen/Zymed, 71-1400) was used . Neuroscience (2006) ncbi | |
rabbit polyclonal | In order to test if HDAC inhibitors affect the expression of tight junction proteins, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . Mol Cancer Res (2004) ncbi | |
rabbit polyclonal | In order to test if lack of junctional cingulin affects tight-junction organization and function, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . J Cell Sci (2004) ncbi | |
rabbit polyclonal | In order to characterize the nuclear functions of ZO-2, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . Exp Cell Res (2004) ncbi | |
rabbit polyclonal | In order to characterize the disruption of the barrier integrity in rat ileum after irradiation, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . Can J Physiol Pharmacol (2004) ncbi | |
rabbit polyclonal | In order to examine the role of nuclear ZO-2, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . Exp Cell Res (2004) ncbi | |
rabbit polyclonal | In order to investigate the use of vitamin D analogues to treat colon cancer, Invitrogen TJP2 antibody (Zymed, 71-1400) was used . J Cell Biol (2001) ncbi |
Cell Signaling Technology
rabbit polyclonal |
| Cell Signaling Technology TJP2 antibody (Cell Signaling Technology, 2847) was used in western blot on human samples at 1:1000 (fig s8). J Clin Invest (2016) ncbi |
rabbit polyclonal |
| Cell Signaling Technology TJP2 antibody (Cell Signaling Technology, 2847) was used in immunohistochemistry on mouse samples at 1:100 (fig 5b) and in western blot on mouse samples at 1:1000 (fig 5f). Endocrinology (2015) ncbi |
rabbit polyclonal |
| In order to determine the precise role of actin in the neural epithelium, Cell Signaling Technology TJP2 antibody (Cell Signaling, 2847) was used in immunohistochemistry on mouse samples at 1:200 (fig 7). Development (2015) ncbi |
Articles Reviewed
- Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher
- de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
- Puerta Guardo H, Raya Sandino A, Gonzalez Mariscal L, Rosales V, Ayala Davila J, Chávez Mungía B, et al. The cytokine response of U937-derived macrophages infected through antibody-dependent enhancement of dengue virus disrupts cell apical-junction complexes and increases vascular permeability. J Virol. 2013;87:7486-501 pubmed publisher
- Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13 pubmed
- Huerta M, Munoz R, Tapia R, Soto Reyes E, Ramírez L, Recillas Targa F, et al. Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. Mol Biol Cell. 2007;18:4826-36 pubmed
- Hernandez S, Chavez Munguia B, Gonzalez Mariscal L. ZO-2 silencing in epithelial cells perturbs the gate and fence function of tight junctions and leads to an atypical monolayer architecture. Exp Cell Res. 2007;313:1533-47 pubmed
- Ciolofan C, Li X, Olson C, Kamasawa N, Gebhardt B, Yasumura T, et al. Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina. Neuroscience. 2006;140:433-51 pubmed
- Bordin M, D Atri F, Guillemot L, Citi S. Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. Mol Cancer Res. 2004;2:692-701 pubmed
- Guillemot L, Hammar E, Kaister C, Ritz J, Caille D, Jond L, et al. Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression. J Cell Sci. 2004;117:5245-56 pubmed
- Jaramillo B, Ponce A, Moreno J, Betanzos A, Huerta M, Lopez Bayghen E, et al. Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells. Exp Cell Res. 2004;297:247-58 pubmed
- Dublineau I, Lebrun F, Grison S, Griffiths N. Functional and structural alterations of epithelial barrier properties of rat ileum following X-irradiation. Can J Physiol Pharmacol. 2004;82:84-93 pubmed
- Betanzos A, Huerta M, Lopez Bayghen E, Azuara E, Amerena J, Gonzalez Mariscal L. The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp Cell Res. 2004;292:51-66 pubmed
- Pálmer H, González Sancho J, Espada J, Berciano M, Puig I, Baulida J, et al. Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol. 2001;154:369-87 pubmed
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