This is a Validated Antibody Database (VAD) review about dog SPTAN1, based on 6 published articles (read how Labome selects the articles), using SPTAN1 antibody in all methods. It is aimed to help Labome visitors find the most suited SPTAN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SPTAN1 synonym: spectrin alpha chain, non-erythrocytic 1; cardiomyocyte alpha-spectrin; sequence with a GC signal; spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)

BD Biosciences
mouse monoclonal (42/B-Spectrin II)
  • immunohistochemistry; mouse; fig 4b
BD Biosciences SPTAN1 antibody (BD Bioscience, 612562) was used in immunohistochemistry on mouse samples (fig 4b). EMBO Rep (2017) ncbi
mouse monoclonal (42/B-Spectrin II)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2c
  • immunohistochemistry; chicken; 1:500; loading ...; fig 9a
In order to elucidate that Emx2 expression is required to reverse hair bundles from their 'default' polarity in the macula and neuromast, BD Biosciences SPTAN1 antibody (BD Biosciences, 612562) was used in immunohistochemistry on mouse samples at 1:500 (fig 2c) and in immunohistochemistry on chicken samples at 1:500 (fig 9a). elife (2017) ncbi
mouse monoclonal (42/B-Spectrin II)
  • immunocytochemistry; mouse; loading ...; fig s6a
BD Biosciences SPTAN1 antibody (BD Biosciences, 612563) was used in immunocytochemistry on mouse samples (fig s6a). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (42/B-Spectrin II)
  • immunocytochemistry; mouse; 1:200; fig 1
  • immunocytochemistry; rat; 1:200; fig 2
BD Biosciences SPTAN1 antibody (BD Biosciences, 612563) was used in immunocytochemistry on mouse samples at 1:200 (fig 1) and in immunocytochemistry on rat samples at 1:200 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (42/B-Spectrin II)
  • immunocytochemistry; rat; fig 7
BD Biosciences SPTAN1 antibody (BD Biosciences, 612563) was used in immunocytochemistry on rat samples (fig 7). elife (2014) ncbi
mouse monoclonal (42/B-Spectrin II)
  • immunohistochemistry; rat; 1:400
BD Biosciences SPTAN1 antibody (BD Biosciences, 612562) was used in immunohistochemistry on rat samples at 1:400. Hum Mol Genet (2015) ncbi
Articles Reviewed
  1. Vogl C, Butola T, Haag N, Hausrat T, Leitner M, Moutschen M, et al. The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Rep. 2017;18:2015-2029 pubmed publisher
  2. Jiang T, Kindt K, Wu D. Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. elife. 2017;6: pubmed publisher
  3. He J, Zhou R, Wu Z, Carrasco M, Kurshan P, Farley J, et al. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proc Natl Acad Sci U S A. 2016;113:6029-34 pubmed publisher
  4. D Este E, Kamin D, Velte C, Göttfert F, Simons M, Hell S. Subcortical cytoskeleton periodicity throughout the nervous system. Sci Rep. 2016;6:22741 pubmed publisher
  5. Zhong G, He J, Zhou R, LORENZO D, Babcock H, Bennett V, et al. Developmental mechanism of the periodic membrane skeleton in axons. elife. 2014;3: pubmed publisher
  6. Requena T, Cabrera S, Martín Sierra C, Price S, Lysakowski A, Lopez Escamez J. Identification of two novel mutations in FAM136A and DTNA genes in autosomal-dominant familial Meniere's disease. Hum Mol Genet. 2015;24:1119-26 pubmed publisher