This is a Validated Antibody Database (VAD) review about dog SIAH2, based on 3 published articles (read how Labome selects the articles), using SIAH2 antibody in all methods. It is aimed to help Labome visitors find the most suited SIAH2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SIAH2 synonym: E3 ubiquitin-protein ligase SIAH2; seven in absentia homolog 2

Sigma-Aldrich
mouse monoclonal (Siah2-369)
  • western blot; human; fig 1
Sigma-Aldrich SIAH2 antibody (Sigma, S7945) was used in western blot on human samples (fig 1). Cell Cycle (2015) ncbi
mouse monoclonal (Siah2-369)
  • immunocytochemistry; human; 1:100-150
  • western blot; human; 1:300-500
In order to elucidate the role of Nrf2 at the blood brain barrier, Sigma-Aldrich SIAH2 antibody (Sigma, S7945) was used in immunocytochemistry on human samples at 1:100-150 and in western blot on human samples at 1:300-500. PLoS ONE (2015) ncbi
mouse monoclonal (Siah2-369)
  • western blot; human; 1:500; fig 2
Sigma-Aldrich SIAH2 antibody (Sigma, S7945) was used in western blot on human samples at 1:500 (fig 2). Nat Cell Biol (2015) ncbi
Articles Reviewed
  1. Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed publisher
  2. Sajja R, Green K, Cucullo L. Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. PLoS ONE. 2015;10:e0122358 pubmed publisher
  3. Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher