This is a Validated Antibody Database (VAD) review about dog RYR1, based on 76 published articles (read how Labome selects the articles), using RYR1 antibody in all methods. It is aimed to help Labome visitors find the most suited RYR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RYR1 synonym: ryanodine receptor 1; ryanodine receptor 1 (skeletal)

Knockout validation
Invitrogen
mouse monoclonal (34C)
  • western blot knockout validation; mouse; 1:500; fig s1b
In order to assess the importance of RyanR type 3 in Alzheimer disease pathology, Invitrogen RYR1 antibody (Thermo, MA3?C925) was used in western blot knockout validation on mouse samples at 1:500 (fig s1b). Channels (Austin) (2014) ncbi
Invitrogen
mouse monoclonal (34C)
  • western blot; mouse; 1:2000; loading ...; fig 2a
Invitrogen RYR1 antibody (ThermoFisher, MA3-925) was used in western blot on mouse samples at 1:2000 (fig 2a). elife (2019) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; loading ...; fig 1b
Invitrogen RYR1 antibody (Thermo Fisher, MA3-916) was used in western blot on mouse samples (fig 1b). Science (2018) ncbi
mouse monoclonal (34C)
  • western blot; mouse; loading ...; fig 5a
In order to report the effects of short- and long-term high-fat diets on fast-twitch skeletal muscles, Invitrogen RYR1 antibody (Thermo Fisher Scientific, MA3-925) was used in western blot on mouse samples (fig 5a). Physiol Rep (2017) ncbi
mouse monoclonal (C3-33)
  • western blot; rabbit; 1:1000; loading ...; fig 5
In order to report the effects of heart failure on the electrical activity of sinoatrial nodes with and without pharmacological interventions, Invitrogen RYR1 antibody (Thermo Fisher, MA3-916) was used in western blot on rabbit samples at 1:1000 (fig 5). Exp Ther Med (2017) ncbi
mouse monoclonal (34C)
  • immunohistochemistry; mouse; 1:300; fig 3c
  • western blot; mouse; 1:2000; loading ...; fig s2f
In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunohistochemistry on mouse samples at 1:300 (fig 3c) and in western blot on mouse samples at 1:2000 (fig s2f). Nat Commun (2017) ncbi
mouse monoclonal (34C)
  • western blot; human; 1:500; loading ...; fig 1b
In order to determine the role of calcium regulation in sporadic inclusion body myositis, Invitrogen RYR1 antibody (Thermo Fischer, MA3-925) was used in western blot on human samples at 1:500 (fig 1b). Acta Neuropathol Commun (2017) ncbi
mouse monoclonal (34C)
  • western blot; mouse; loading ...; fig 2d
In order to report the physiological role of sarcolipin upregulation in muscle myopathy, Invitrogen RYR1 antibody (Pierce Antibodies, MA3-925) was used in western blot on mouse samples (fig 2d). PLoS ONE (2017) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; 1:1000; loading ...; fig 3e
In order to test the ability of the Notch inhibitor DAPT to convert murine fibroblasts into cardiomyocytes, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in western blot on mouse samples at 1:1000 (fig 3e). Stem Cell Reports (2017) ncbi
mouse monoclonal (34C)
  • western blot; rat; loading ...; fig 2e
In order to assess the role of redox stress in PH-induced diaphragm weakness, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in western blot on rat samples (fig 2e). PLoS ONE (2017) ncbi
mouse monoclonal (C3-33)
  • immunoprecipitation; rat; loading ...
  • western blot; rat; 1:5000; loading ...; fig 6a
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in immunoprecipitation on rat samples and in western blot on rat samples at 1:5000 (fig 6a). Cardiovasc Res (2017) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry - frozen section; sheep; 1:100; loading ...; fig 3a
In order to describe transverse-tubule development in the large mammalian fetal heart, Invitrogen RYR1 antibody (Thermo, MA3- 916) was used in immunohistochemistry - frozen section on sheep samples at 1:100 (fig 3a). J Muscle Res Cell Motil (2016) ncbi
mouse monoclonal (34C)
  • western blot; rat; 1:2500; loading ...; fig 4a
In order to report the effects of eccentric contraction on calpain-dependent proteolysis of calcium ion-regulatory proteins and force production in fast-twitch skeletal muscles, Invitrogen RYR1 antibody (ThermoFisher Scientific, MA-925) was used in western blot on rat samples at 1:2500 (fig 4a). J Appl Physiol (1985) (2017) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:1000; fig 5a
In order to examine the effects of sildenafil on skeletal muscle, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:1000 (fig 5a). Exp Mol Med (2016) ncbi
mouse monoclonal (34C)
  • western blot; human; loading ...; fig 8a
In order to study the ryanodine receptor inhibitory action of the calmodulin p.Phe142Leu mutation, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in western blot on human samples (fig 8a). J Biol Chem (2017) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 7a
In order to suggest that ectopic beats originating in the myocardial sleeves of the pulmonary veins occur only under pathological conditions, Invitrogen RYR1 antibody (Thermo Fisher Scientific, MA3-916) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 7a). Exp Ther Med (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; loading ...; fig 4a
In order to test if calcium dysregulation contributes to muscle dysfunction in patients with chronic obstructive pulmonary disease, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on mouse samples (fig 4a). Muscle Nerve (2017) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; 1:5000; loading ...; fig 2g
In order to explore the role of junctophilin-2 in the ventricular muscle cells of the heart, Invitrogen RYR1 antibody (Thermo, MA3916) was used in western blot on mouse samples at 1:5000 (fig 2g). J Cell Sci (2016) ncbi
mouse monoclonal (34C)
  • western blot; human; 1:1000; loading ...; fig 4a
In order to investigate the role of the S6 cytoplasmic region in the function of cardiac ryanodine receptor, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on human samples at 1:1000 (fig 4a). J Biol Chem (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:1000; fig s2
In order to clarify the role of ryanodine receptor mutation in channel function, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:1000 (fig s2). J Biol Chem (2016) ncbi
mouse monoclonal (C3-33)
  • immunocytochemistry; mouse; loading ...
  • western blot; mouse; loading ...; fig 1d
  • immunoprecipitation; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 1e
In order to investigate the function of striated muscle preferentially expressed gene, Invitrogen RYR1 antibody (Thermo Fisher, MA3-916) was used in immunocytochemistry on mouse samples , in western blot on mouse samples (fig 1d), in immunoprecipitation on human samples (fig 1e) and in western blot on human samples (fig 1e). Circ Res (2017) ncbi
mouse monoclonal (34C)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1a
  • western blot; mouse; 1:1000
In order to examine the effects of marijuana on CB1R activation in skeletal muscle, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in immunohistochemistry on mouse samples at 1:500 (fig 1a) and in western blot on mouse samples at 1:1000. J Physiol (2016) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3c
  • immunohistochemistry; rat; 1:50; loading ...; fig 3b
In order to test if mitochondrial calcium uniporter concentrated at the mitochondria-sarcoplasmic reticulum interface promotes calcium transfer, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in immunohistochemistry on mouse samples at 1:50 (fig 3c) and in immunohistochemistry on rat samples at 1:50 (fig 3b). J Biol Chem (2016) ncbi
mouse monoclonal (34C)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2c
In order to test if neuromodulatory G-protein coupled receptors use beta-arrestin-dependent signaling to modulate neuronal excitability, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in immunohistochemistry on mouse samples at 1:100 (fig 2c). Cell Rep (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; rabbit; 1:2000; fig 6a
In order to investigate the regulation of Ca(2+)/calmodulin-dependent protein kinase II in sinoatrial node cells, Invitrogen RYR1 antibody (Thermo Scientific, C3-33) was used in western blot on rabbit samples at 1:2000 (fig 6a). Am J Physiol Heart Circ Physiol (2016) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; mouse; loading ...; fig 2e
In order to elucidate how RYR1 mutations contributes to bleeding abnormalities, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on mouse samples (fig 2e). Sci Signal (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:2000; fig 1
In order to characterize calcium waves propagation in rat ventricular myocytes by the role of SERCA and the sarcoplasmic reticulum calcium content, Invitrogen RYR1 antibody (Thermo Fisher, MA3-925) was used in western blot on mouse samples at 1:2000 (fig 1). Arch Biochem Biophys (2016) ncbi
mouse monoclonal (34C)
  • proximity ligation assay; mouse; 1:500; fig 4
In order to study protection against acute myocardial infaction via hearts lacking Mfn1 and Mfn2, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in proximity ligation assay on mouse samples at 1:500 (fig 4). Cell Death Dis (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; fig 5
In order to determine the reduction of store overload-induced calcium release and protection against ventricular arrhythmia due to inhibition of Rac1, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-916) was used in western blot on mouse samples (fig 5). J Cell Mol Med (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:5000; fig 2
In order to analyze slow twitch skeletal muscles and the role of the JP45-calsequestrin complex on calcium entry, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples at 1:5000 (fig 2). J Biol Chem (2016) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; pig; 1:200; fig 6
In order to characterize modulation of ryanodine receptors during beta-adrenergic stimulation and restriction to the dyadic cleft via nictric oxide synthase-1 and calcium/calmodulin-dependent kinase II, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on pig samples at 1:200 (fig 6). J Physiol (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; rat; 1:1000; fig s1
In order to investigate left ventricular cardiomyocytes from post-infaction rats with and without heart failure after beta-adrenoceptor stimulation to revela Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion, Invitrogen RYR1 antibody (Thermo Fisher Scientific, MA3-916) was used in western blot on rat samples at 1:1000 (fig s1). PLoS ONE (2016) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 1
In order to assess the function and characterization of extraocular muscles and obicularis oculi, Invitrogen RYR1 antibody (ThermoFisher Scientific, MA3-925) was used in immunocytochemistry on human samples (fig 4) and in western blot on human samples (fig 1). J Gen Physiol (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; fig 1
  • western blot; human; fig 2
In order to investigate the deficiency that affects SERCA expression and function in the skeletal muscle by Calpain 3, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-925) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 2). Expert Rev Mol Med (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; loading ...; fig 7e
In order to study the role of angiotensin receptor-associated protein Atrap on cardiac Ca2+-ATPase SERCA2a, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in western blot on mouse samples (fig 7e). Cardiovasc Res (2016) ncbi
mouse monoclonal (34C)
  • western blot; mouse; fig 2
In order to characterize induction by doxorubicin causing early oxidative damage and the source of production, effect of Ca(2+) transporters in HL-1 cardiomyocytes and protection by GKT137831, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in western blot on mouse samples (fig 2). Arch Biochem Biophys (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; 1:1000; loading ...; fig s8a
In order to elucidate how DWORF activates the SERCA pump, Invitrogen RYR1 antibody (Pierce, C3-33) was used in western blot on mouse samples at 1:1000 (fig s8a). Science (2016) ncbi
mouse monoclonal (C3-33)
  • immunocytochemistry; rat; fig 3
  • western blot; rat; fig 2
In order to study the effects of ascending aortic banding on calcium handling in rat isolated atrial myocytes, Invitrogen RYR1 antibody (Thermo Scientific, MA3916) was used in immunocytochemistry on rat samples (fig 3) and in western blot on rat samples (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal (34C)
  • western blot; mouse; fig 1
In order to study the Ca(2+)-dependent protein-protein interactions within cardiac sarcoplasmic reticulum Ca(2+) release units, Invitrogen RYR1 antibody (ABR, MA3-925) was used in western blot on mouse samples (fig 1). Mol Cells (2016) ncbi
mouse monoclonal (34C)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 6
In order to investigate LRRC10 and its role in cardiac function under pressure, Invitrogen RYR1 antibody (Thermo Pierce, MA3-925) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 6). Am J Physiol Heart Circ Physiol (2016) ncbi
mouse monoclonal (34C)
  • immunohistochemistry - frozen section; zebrafish ; fig 5
In order to analyze Danio rerio for calsequestrins in cardiac and skeletal muscle, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in immunohistochemistry - frozen section on zebrafish samples (fig 5). J Muscle Res Cell Motil (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; fig 3
In order to maintain cardiac function through a heterozygous deletion of sarcolipin, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-916) was used in western blot on mouse samples (fig 3). Am J Physiol Heart Circ Physiol (2016) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; 1:2000; fig 1
In order to research bone metastases in mice by excess TGF-beta mediating muscle weakness, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-916) was used in western blot on mouse samples at 1:2000 (fig 1). Nat Med (2015) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:2500
In order to investigate the impact of Tmem65 on heart development, Invitrogen RYR1 antibody (Life Technologies, 34C) was used in western blot on mouse samples at 1:2500. Nat Commun (2015) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry; rat; fig 1
In order to characterize Ca2+ release patterns in cardiomyocytes and examine the effects of heterogeneous organization of RyR clusters, mitochondria, and myofibrils, Invitrogen RYR1 antibody (Affinity Bioreagents, C3-33) was used in immunohistochemistry on rat samples (fig 1). PLoS Comput Biol (2015) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry - frozen section; dog; 1:100; fig 1
In order to study dyssynchronous heart failure after cardiac resynchronization therapy, Invitrogen RYR1 antibody (ThermoFisher Scientific, MA3-916) was used in immunohistochemistry - frozen section on dog samples at 1:100 (fig 1). Circ Heart Fail (2015) ncbi
mouse monoclonal (C3-33)
  • immunocytochemistry; rat; 1:200; fig 1
In order to study t-tubule function during cardiac failure, Invitrogen RYR1 antibody (Thermo Fisher Scientific,, MA3-916) was used in immunocytochemistry on rat samples at 1:200 (fig 1). J Mol Cell Cardiol (2015) ncbi
mouse monoclonal (34C)
  • western blot; mouse
  • western blot; human
In order to study SERCA dysfunction in mice overexpressing phospholamban, Invitrogen RYR1 antibody (Pierce Antibodies, MA3-925) was used in western blot on mouse samples and in western blot on human samples . Dis Model Mech (2015) ncbi
mouse monoclonal (34C)
  • western blot; mouse; fig 1
In order to determine the mechanisms that reduce ryanodine receptor 1 in patients with congenital myopathies, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples (fig 1). Hum Mol Genet (2015) ncbi
mouse monoclonal (34C)
  • western blot; human
In order to determine which RYR1 variants contribute to malignant hyperthermia, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on human samples . Neuromuscul Disord (2015) ncbi
mouse monoclonal (34C)
  • western blot; mouse
In order to investigate Mitsugumin 56 in skeletal muscle maturation using knockout mice, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on mouse samples . FEBS Lett (2015) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry - frozen section; human; 1:100
In order to describe a method of multi-scale imaging of human cardiac tissue, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in immunohistochemistry - frozen section on human samples at 1:100. Methods (2015) ncbi
mouse monoclonal (C3-33)
  • immunocytochemistry; mouse; 1:200; tbl 1
In order to examine the interaction between store-operated calcium entry and store content and its role in cardiac pacemaking, Invitrogen RYR1 antibody (ABR, MA3-916) was used in immunocytochemistry on mouse samples at 1:200 (tbl 1). Front Physiol (2015) ncbi
mouse monoclonal (C3-33)
  • immunohistochemistry; rat; 1:100
In order to quantify the spatial distribution ryanodine receptors throughout the myoplasm, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in immunohistochemistry on rat samples at 1:100. J Mol Cell Cardiol (2015) ncbi
mouse monoclonal (C3-33)
  • western blot; human; 1:5000
  • immunoprecipitation; mouse
  • western blot; mouse; 1:5000
In order to study the loss of thd miR-106b-25 cluster in the pathogenesis of atrial fibrillation, Invitrogen RYR1 antibody (Thermo Fisher Scientific, MA3-916) was used in western blot on human samples at 1:5000, in immunoprecipitation on mouse samples and in western blot on mouse samples at 1:5000. Circ Arrhythm Electrophysiol (2014) ncbi
mouse monoclonal (34C)
  • immunohistochemistry; mouse; 1 ug/ml
In order to study a missense mutation in the calsequestrin-1 gene discovered in a group of patients with a myopathy, Invitrogen RYR1 antibody (Thermo Scientific, 34C) was used in immunohistochemistry on mouse samples at 1 ug/ml. Hum Mutat (2014) ncbi
mouse monoclonal (34C)
  • immunohistochemistry - free floating section; mouse; fig 1
In order to study Kv2.1 expression and phosphorylation, Invitrogen RYR1 antibody (Pierce, MA3925) was used in immunohistochemistry - free floating section on mouse samples (fig 1). J Comp Neurol (2014) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:1000
In order to determine how nuclear calcium signaling controls nuclear BK channels that regulate gene expression, Invitrogen RYR1 antibody (Thermo, MA3-925) was used in western blot on mouse samples at 1:1000. Nat Neurosci (2014) ncbi
mouse monoclonal (G-1)
  • immunocytochemistry; rat
In order to study the effect of regional t-tubule density during cardiomyocyte Ca(2+) homeostasis, Invitrogen RYR1 antibody (Thermo Scientific, MA1-83782) was used in immunocytochemistry on rat samples . Am J Physiol Heart Circ Physiol (2014) ncbi
mouse monoclonal (C3-33)
  • immunocytochemistry; mouse
  • immunohistochemistry; mouse
  • immunocytochemistry; rabbit
  • immunohistochemistry; rabbit
In order to study the contribution of nuclear Ca(2+) handling on the development and progression of heart failure, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in immunocytochemistry on mouse samples , in immunohistochemistry on mouse samples , in immunocytochemistry on rabbit samples and in immunohistochemistry on rabbit samples . Circulation (2014) ncbi
mouse monoclonal (34C)
  • western blot; mouse; 1:2000
In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in western blot on mouse samples at 1:2000. J Neurosci (2014) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse; 1:1000
In order to study the role of exagerated Ca(2+) signaling mediated by InsP3 receptor1 in the pathogenesis of mutant presenilin-linked Alzheimer's disease, Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-916) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
mouse monoclonal (34C)
  • immunohistochemistry - free floating section; rat; 1 ug/ml
In order to study Kv2.1 function and membrane excitability in the axon initial segment, Invitrogen RYR1 antibody (Pierce, MA3-925) was used in immunohistochemistry - free floating section on rat samples at 1 ug/ml. J Comp Neurol (2014) ncbi
mouse monoclonal (34C)
  • western blot knockout validation; mouse; 1:500; fig s1b
In order to assess the importance of RyanR type 3 in Alzheimer disease pathology, Invitrogen RYR1 antibody (Thermo, MA3?C925) was used in western blot knockout validation on mouse samples at 1:500 (fig s1b). Channels (Austin) (2014) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; mouse
In order to study the intracellular role of sorcin, Invitrogen RYR1 antibody (Antibody Directory, MA3-925) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; pig; 1:200
In order to study Ca(2+) handling in Purkinje cells, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-925) was used in immunocytochemistry on pig samples at 1:200. J Physiol (2013) ncbi
mouse monoclonal (34C)
  • western blot; human; fig 2
In order to investigate a novel skeletal RYR1 mutation in an autosomal recessive heterogeneous congenital myopathy, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in western blot on human samples (fig 2). PLoS ONE (2013) ncbi
mouse monoclonal (C3-33)
  • western blot; rat
  • western blot; mouse
In order to study the mechanisms underlying the effects of zinc on cardiomyocyte contraction-relaxation, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in western blot on rat samples and in western blot on mouse samples . Am J Physiol Heart Circ Physiol (2013) ncbi
mouse monoclonal (34C)
  • immunohistochemistry; mouse
In order to assess how deregulation of the protocadherin gene FAT1 changes muscle shape implying a role for the pathogenesis of facioscapulohumeral dystrophy, Invitrogen RYR1 antibody (Thermo scientific, MA3-925) was used in immunohistochemistry on mouse samples . PLoS Genet (2013) ncbi
mouse monoclonal (C3-33)
  • western blot; rat
In order to study the effect of Zn(2+) on cardiomyocyte relaxation in a hyperglycemic diabetic rat model expressing only beta-myosin heavy chain in the heart, Invitrogen RYR1 antibody (Thermo Scientific, MA3-916) was used in western blot on rat samples . Cardiovasc Diabetol (2012) ncbi
mouse monoclonal (34C)
  • western blot; human
In order to investigate the abnormalities of calcium handling proteins in skeletal and heart muscle during heart failure, Invitrogen RYR1 antibody (Pierce, 34C) was used in western blot on human samples . J Card Fail (2012) ncbi
mouse monoclonal (34C)
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 1
In order to study calcium homeostasis and excitation-contraction coupling in cultured myotubes derived from two patients with Rippling muscle disease, Invitrogen RYR1 antibody (Thermo Scientific, MA3-925) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 1). Hum Mutat (2011) ncbi
mouse monoclonal (34C)
  • immunohistochemistry - frozen section; mouse; 1:800
  • immunocytochemistry; mouse; 1:800
Invitrogen RYR1 antibody (Affinity Bioreagents, MA3-925) was used in immunohistochemistry - frozen section on mouse samples at 1:800 and in immunocytochemistry on mouse samples at 1:800. J Comp Neurol (2008) ncbi
mouse monoclonal (34C)
  • immunoprecipitation; rabbit; fig 5
  • western blot; rabbit; fig 5
In order to suggest that S100A1 is an inhibitory modulator of RyR2 function at diastolic calcium concentrations in rabbit ventricular cardiomyocytes, Invitrogen RYR1 antibody (ABR, MA-3-925) was used in immunoprecipitation on rabbit samples (fig 5) and in western blot on rabbit samples (fig 5). Cell Calcium (2007) ncbi
mouse monoclonal (C3-33)
  • western blot; mouse
In order to demonstrate that ablation of splicing factor SC35 in the heart causes dilated cardiomyopathy, Invitrogen RYR1 antibody (Affinity BioReagents, MA3-916) was used in western blot on mouse samples . EMBO J (2004) ncbi
Abcam
mouse monoclonal (C3-33)
  • immunocytochemistry; rabbit; 1:100; loading ...; fig 6b
In order to present structural evidence indicating the formation of microdomains between the acidic and sarcoplasmic reticulum calcium stores in cardiac myocytes, Abcam RYR1 antibody (Abcam, ab2827) was used in immunocytochemistry on rabbit samples at 1:100 (fig 6b). Sci Rep (2017) ncbi
mouse monoclonal (C3-33)
  • western blot; rat; 1:1000; loading ...; fig 5b
Abcam RYR1 antibody (Abcam, Ab2827) was used in western blot on rat samples at 1:1000 (fig 5b). PLoS ONE (2015) ncbi
Sigma-Aldrich
mouse monoclonal (34C)
  • western blot; human; fig 3f
In order to study mechanisms by which chronic beta2-adrenergic stimulation enhances muscle force and power output during maximal cycle ergometer exercise in young men, Sigma-Aldrich RYR1 antibody (SigmaAldrich, R129) was used in western blot on human samples (fig 3f). J Appl Physiol (1985) (2015) ncbi
Articles Reviewed
  1. Dai W, Laforest B, Tyan L, Shen K, Nadadur R, Alvarado F, et al. A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice. elife. 2019;8: pubmed publisher
  2. Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, et al. E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator. Science. 2018;362: pubmed publisher
  3. Eshima H, Tamura Y, Kakehi S, Kurebayashi N, Murayama T, Nakamura K, et al. Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle. Physiol Rep. 2017;5: pubmed publisher
  4. Chang S, Chuang H, Chen Y, Kao Y, Lin Y, Yeh Y, et al. Heart failure modulates electropharmacological characteristics of sinoatrial nodes. Exp Ther Med. 2017;13:771-779 pubmed publisher
  5. Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  6. Amici D, Pinal Fernández I, Mázala D, Lloyd T, Corse A, Christopher Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5:24 pubmed publisher
  7. Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed publisher
  8. Abad M, Hashimoto H, Zhou H, Morales M, Chen B, Bassel Duby R, et al. Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity. Stem Cell Reports. 2017;8:548-560 pubmed publisher
  9. Himori K, Abe M, Tatebayashi D, Lee J, Westerblad H, Lanner J, et al. Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension. PLoS ONE. 2017;12:e0169146 pubmed publisher
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