This is a Validated Antibody Database (VAD) review about dog RPS6KA1, based on 20 published articles (read how Labome selects the articles), using RPS6KA1 antibody in all methods. It is aimed to help Labome visitors find the most suited RPS6KA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RPS6KA1 synonym: ribosomal protein S6 kinase alpha-1

Cell Signaling Technology
rabbit monoclonal (D6D5)
  • western blot; human; fig 6d
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 8408) was used in western blot on human samples (fig 6d). Cell (2018) ncbi
rabbit monoclonal (D3H11)
  • western blot; human; loading ...; fig s5o
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 11989) was used in western blot on human samples (fig s5o). Nature (2017) ncbi
rabbit monoclonal (D3H11)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 11989) was used in western blot on human samples (fig 1a). Mol Oncol (2017) ncbi
rabbit monoclonal (D3H11)
  • western blot; human; 1:1000; loading ...; fig 5c
  • immunohistochemistry; mouse; 1:400; loading ...; fig 7h
Cell Signaling Technology RPS6KA1 antibody (cell signalling, 11989) was used in western blot on human samples at 1:1000 (fig 5c) and in immunohistochemistry on mouse samples at 1:400 (fig 7h). Sci Rep (2017) ncbi
rabbit monoclonal (D1E9)
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 8753) was used in western blot on human samples at 1:1000 (fig 1e). Am J Physiol Cell Physiol (2017) ncbi
rabbit monoclonal (D1E9)
  • western blot; human; fig 1c
In order to assess the effects of LY3009120, a panRAF and RAF dimer inhibitor, in human models of colorectal cancer, Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 8753) was used in western blot on human samples (fig 1c). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 9341) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
rabbit monoclonal (D3H11)
  • western blot; human; fig 1c
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 11989) was used in western blot on human samples (fig 1c). Exp Mol Med (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 4
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling Tech, 9341) was used in immunocytochemistry on human samples at 1:200 (fig 4). Aging (Albany NY) (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling Technology, 9341) was used in western blot on human samples (fig 4). Cell Commun Signal (2016) ncbi
rabbit monoclonal (D6D5)
  • western blot; human; 1:2000; loading ...; fig 3g
In order to identify and study roles for MAP3K8 in high-grade serous ovarian carcinomas, Cell Signaling Technology RPS6KA1 antibody (Cell Signalling, 8408) was used in western blot on human samples at 1:2000 (fig 3g). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s3
Cell Signaling Technology RPS6KA1 antibody (Cell signaling, 9341) was used in western blot on mouse samples at 1:1000 (fig s3). Sci Rep (2015) ncbi
rabbit polyclonal
  • other; mouse; 1:1000; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 9341) was used in other on mouse samples at 1:1000 (fig s1). Front Microbiol (2015) ncbi
rabbit monoclonal (D6D5)
  • immunohistochemistry; Domestic guinea pig; fig s6
In order to characterize targeting of colonic crypts by bioimage analysis of Shigella infection, Cell Signaling Technology RPS6KA1 antibody (Cell Signaling, 8408) was used in immunohistochemistry on Domestic guinea pig samples (fig s6). Proc Natl Acad Sci U S A (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling Technology., 9341) was used in western blot on human samples . Cell Signal (2015) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; tbl s2
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling Technology, 9341S) was used in reverse phase protein lysate microarray on human samples (tbl s2). Mol Syst Biol (2015) ncbi
rabbit monoclonal (D6D5)
  • western blot; human; 1:1000; fig 2c
Cell Signaling Technology RPS6KA1 antibody (Cell Signaling Technology, 8408) was used in western blot on human samples at 1:1000 (fig 2c). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology RPS6KA1 antibody (Cell Signalling, 9341) was used in western blot on rat samples . J Appl Physiol (1985) (2012) ncbi
BD Biosciences
mouse monoclonal (78/RSK)
  • western blot; human; fig 2
BD Biosciences RPS6KA1 antibody (BD Biosciences, 610226) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
mouse monoclonal (78/RSK)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences RPS6KA1 antibody (BD, 78) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Articles Reviewed
  1. Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed publisher
  2. Schafer S, Viswanathan S, Widjaja A, Lim W, Moreno Moral A, Delaughter D, et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017;552:110-115 pubmed publisher
  3. Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  4. Fu S, Xu H, Gu M, Liu C, Wang Q, Wan X, et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep. 2017;7:43771 pubmed publisher
  5. Gross S, Rotwein P. Quantification of growth factor signaling and pathway cross talk by live-cell imaging. Am J Physiol Cell Physiol. 2017;312:C328-C340 pubmed publisher
  6. Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed publisher
  7. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  8. Park Y, Nam H, Do M, Lee J. The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles. Exp Mol Med. 2016;48:e250 pubmed publisher
  9. Wen Y, Li H, Zeng Y, Wen W, Pendleton K, Lui V, et al. MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin. Oncotarget. 2016;7:23300-11 pubmed publisher
  10. Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
  11. Hennig A, Markwart R, Wolff K, Schubert K, Cui Y, Prior I, et al. Feedback activation of neurofibromin terminates growth factor-induced Ras activation. Cell Commun Signal. 2016;14:5 pubmed publisher
  12. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  13. Gruosso T, Garnier C, Abélanet S, Kieffer Y, Lemesre V, Bellanger D, et al. MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas. Nat Commun. 2015;6:8583 pubmed publisher
  14. Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed publisher
  15. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  16. Arena E, Campbell Valois F, Tinevez J, Nigro G, Sachse M, Moya Nilges M, et al. Bioimage analysis of Shigella infection reveals targeting of colonic crypts. Proc Natl Acad Sci U S A. 2015;112:E3282-90 pubmed publisher
  17. Roffé M, Lupinacci F, Soares L, Hajj G, Martins V. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. Cell Signal. 2015;27:1630-42 pubmed publisher
  18. Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
  19. Stolze B, Reinhart S, Bulllinger L, Fröhling S, Scholl C. Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines. Sci Rep. 2015;5:8535 pubmed publisher
  20. Schweitzer G, Arias E, Cartee G. Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation. J Appl Physiol (1985). 2012;113:1852-61 pubmed publisher