This is a Validated Antibody Database (VAD) review about dog PRKAR1A, based on 11 published articles (read how Labome selects the articles), using PRKAR1A antibody in all methods. It is aimed to help Labome visitors find the most suited PRKAR1A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PRKAR1A synonym: cAMP-dependent protein kinase type I-alpha regulatory subunit; protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

Santa Cruz Biotechnology
mouse monoclonal (20)
  • western blot; mouse
Santa Cruz Biotechnology PRKAR1A antibody (Santa Cruz, sc-136231) was used in western blot on mouse samples . Biochem Pharmacol (2015) ncbi
BD Biosciences
mouse monoclonal (18/PKA [RI)
  • western blot; human; 0.8 ug/ml; loading ...; fig 1d
BD Biosciences PRKAR1A antibody (BD Biosciences, 610166) was used in western blot on human samples at 0.8 ug/ml (fig 1d). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (20/PKA RI)
  • western blot; human; 0.8 ug/ml; loading ...; fig s2f
BD Biosciences PRKAR1A antibody (BD Biosciences, 610609) was used in western blot on human samples at 0.8 ug/ml (fig s2f). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (20/PKA RI)
  • western blot; mouse; loading ...; fig 6a
BD Biosciences PRKAR1A antibody (BD Biosciences, 610609) was used in western blot on mouse samples (fig 6a). Diabetes (2017) ncbi
mouse monoclonal (20/PKA RI)
  • immunohistochemistry; rat; 1:100; loading ...; fig 1
  • western blot; rat; 1:1000; loading ...; fig 2b
In order to evaluate if Ezrin associates with connexin 43 in cell types that form stable gap junctions and serve as an A kinase anchoring protein, BD Biosciences PRKAR1A antibody (BD, 610610) was used in immunohistochemistry on rat samples at 1:100 (fig 1) and in western blot on rat samples at 1:1000 (fig 2b). Cell Signal (2017) ncbi
mouse monoclonal (20/PKA RI)
  • western blot; human; 1:1000; loading ...; fig 4c
In order to elucidate the mechanisms by which ARHGAP36 blocks protein kinase A signaling, BD Biosciences PRKAR1A antibody (BD, 610610) was used in western blot on human samples at 1:1000 (fig 4c). Nat Commun (2016) ncbi
mouse monoclonal (18/PKA [RI)
  • western blot; human; fig 1
BD Biosciences PRKAR1A antibody (BD Bioscience, 610166) was used in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (20/PKA RI)
  • immunoprecipitation; human; fig 3
BD Biosciences PRKAR1A antibody (BD Biosciences, 610610) was used in immunoprecipitation on human samples (fig 3). Pediatr Res (2016) ncbi
mouse monoclonal (20/PKA RI)
  • western blot; mouse; fig s2
BD Biosciences PRKAR1A antibody (BD Biosciences, 610610) was used in western blot on mouse samples (fig s2). Nat Commun (2015) ncbi
mouse monoclonal (18/PKA [RI)
  • western blot; mouse; fig s2
BD Biosciences PRKAR1A antibody (BD Biosciences, 610165) was used in western blot on mouse samples (fig s2). Nat Commun (2015) ncbi
mouse monoclonal (18/PKA [RI)
  • immunoprecipitation; human; fig 4
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 3
BD Biosciences PRKAR1A antibody (BD Transduction Laboratories, 610165) was used in immunoprecipitation on human samples (fig 4), in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 3). Mol Cell Biol (2015) ncbi
mouse monoclonal (18/PKA [RI)
  • western blot; human
In order to study the association of PRKAR1B mutation with a new neurodegenerative disorder, BD Biosciences PRKAR1A antibody (Becton Dickinson Laboratories, 610166) was used in western blot on human samples . Brain (2014) ncbi
mouse monoclonal (20/PKA RI)
  • western blot; mouse
BD Biosciences PRKAR1A antibody (BD Biosciences, 610609) was used in western blot on mouse samples . Cell Death Differ (2013) ncbi
Articles Reviewed
  1. Walker Gray R, Stengel F, Gold M. Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches. Proc Natl Acad Sci U S A. 2017;114:10414-10419 pubmed publisher
  2. Kuo T, Chen T, Lee R, Nguyen N, Broughton A, Zhang D, et al. Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. Diabetes. 2017;66:1601-1610 pubmed publisher
  3. Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K. A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells. Cell Signal. 2017;32:1-11 pubmed publisher
  4. Eccles R, Czajkowski M, Barth C, Müller P, McShane E, Grunwald S, et al. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun. 2016;7:12963 pubmed publisher
  5. Bachmann V, Mayrhofer J, Ilouz R, Tschaikner P, Raffeiner P, Röck R, et al. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling. Proc Natl Acad Sci U S A. 2016;113:7786-91 pubmed publisher
  6. Riggle K, Riehle K, Kenerson H, Turnham R, Homma M, Kazami M, et al. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Pediatr Res. 2016;80:110-8 pubmed publisher
  7. Yang L, McKnight G. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nat Commun. 2015;6:8237 pubmed publisher
  8. Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines. Biochem Pharmacol. 2015;98:119-31 pubmed publisher
  9. Iwano S, Satou A, Matsumura S, Sugiyama N, Ishihama Y, Toyoshima F. PCTK1 regulates integrin-dependent spindle orientation via protein kinase A regulatory subunit KAP0 and myosin X. Mol Cell Biol. 2015;35:1197-208 pubmed publisher
  10. Wong T, Chiu W, Breedveld G, Li K, Verkerk A, Hondius D, et al. PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. Brain. 2014;137:1361-73 pubmed publisher
  11. Lee Y, Moujalled D, Doerflinger M, Gangoda L, Weston R, Rahimi A, et al. CREB-binding protein (CBP) regulates ?-adrenoceptor (?-AR)-mediated apoptosis. Cell Death Differ. 2013;20:941-52 pubmed publisher