This is a Validated Antibody Database (VAD) review about dog LMNA, based on 29 published articles (read how Labome selects the articles), using LMNA antibody in all methods. It is aimed to help Labome visitors find the most suited LMNA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LMNA synonym: lamin; prelamin-A/C

Knockout validation
Abcam
mouse monoclonal (131C3)
  • western blot knockout validation; human; loading ...; fig 3b
Abcam LMNA antibody (abcam, ab8984) was used in western blot knockout validation on human samples (fig 3b). Nature (2019) ncbi
Abcam
mouse monoclonal (131C3)
  • western blot knockout validation; human; loading ...; fig 3b
Abcam LMNA antibody (abcam, ab8984) was used in western blot knockout validation on human samples (fig 3b). Nature (2019) ncbi
mouse monoclonal (131C3)
  • immunocytochemistry; mouse; loading ...; fig s5d
Abcam LMNA antibody (Abcam, ab8984) was used in immunocytochemistry on mouse samples (fig s5d). Genome Biol (2018) ncbi
mouse monoclonal (131C3)
  • immunohistochemistry; human; 1:200; loading ...; fig 2c
  • western blot; human; 1:1000; loading ...; fig 4c
Abcam LMNA antibody (Abcam, ab8984) was used in immunohistochemistry on human samples at 1:200 (fig 2c) and in western blot on human samples at 1:1000 (fig 4c). Nat Commun (2018) ncbi
mouse monoclonal (133A2)
  • immunocytochemistry; human; 1:1000; loading ...; fig 1a
In order to investigate the effect of actomyosin on cell nuclear morphology and genome stability, Abcam LMNA antibody (Abcam, ab8980) was used in immunocytochemistry on human samples at 1:1000 (fig 1a). Nat Commun (2017) ncbi
mouse monoclonal (131C3)
  • immunocytochemistry; human; 1:200; loading ...; fig s6
In order to screen for genes involved in mitochondrial DNA maintenance, Abcam LMNA antibody (Abcam, ab8984) was used in immunocytochemistry on human samples at 1:200 (fig s6). Nat Chem Biol (2016) ncbi
mouse monoclonal (131C3)
  • western blot; human; 1:1000; fig 5
In order to determine regulation of expression of Epstein-Barr virus BART microRNAs and long noncoding RNAs in nasopharyngeal carcinoma via NF-kappaB signaling, Abcam LMNA antibody (Abcam, ab8984) was used in western blot on human samples at 1:1000 (fig 5). J Virol (2016) ncbi
mouse monoclonal (133A2)
  • immunocytochemistry; human; 1:500; fig 1
In order to test if progerin elicits spatiotemporal deviations in mitotic processes in Hutchinson-Gilford progeria syndrome fibroblasts, Abcam LMNA antibody (Abcam, ab8980) was used in immunocytochemistry on human samples at 1:500 (fig 1). Oncotarget (2016) ncbi
mouse monoclonal (133A2)
  • immunocytochemistry; human; 1:1000; fig s1
Abcam LMNA antibody (Abcam, ab8980) was used in immunocytochemistry on human samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
mouse monoclonal (133A2)
  • western blot; human; fig 3
Abcam LMNA antibody (Abcam, 133A2) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (131C3)
  • immunocytochemistry; human; 1:500; fig 1
Abcam LMNA antibody (Abcam, ab8984) was used in immunocytochemistry on human samples at 1:500 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (131C3)
  • western blot; human; 1:2000; fig 1
Abcam LMNA antibody (abcam, ab8984) was used in western blot on human samples at 1:2000 (fig 1). Sci Rep (2015) ncbi
mouse monoclonal (133A2)
  • immunocytochemistry; human
Abcam LMNA antibody (Abcam, Ab8980) was used in immunocytochemistry on human samples . Cell Death Differ (2016) ncbi
mouse monoclonal (131C3)
  • western blot; mouse; 1:1000; fig 1
Abcam LMNA antibody (abcam, ab8984) was used in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (133A2)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1
  • immunocytochemistry; human; 1:100; loading ...; fig 4
  • western blot; human; 1:250; loading ...; fig 3b
Abcam LMNA antibody (Abcam, ab8980) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1), in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:250 (fig 3b). Pathol Res Pract (2015) ncbi
mouse monoclonal (131C3)
  • immunocytochemistry; human; 1:200; loading ...
Abcam LMNA antibody (Abcam, ab8984) was used in immunocytochemistry on human samples at 1:200. Mol Hum Reprod (2015) ncbi
mouse monoclonal (133A2)
  • immunocytochemistry; human; 1:100; loading ...
Abcam LMNA antibody (Abcam, ab8980) was used in immunocytochemistry on human samples at 1:100. Mol Hum Reprod (2015) ncbi
mouse monoclonal (131C3)
  • western blot; human; 1:1000
In order to study the expression and the nuclear localization of VPAC1 and VPAC2 in glioma, Abcam LMNA antibody (Abcam, ab8984) was used in western blot on human samples at 1:1000. Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (133A2)
  • western blot; human; 1:2000; loading ...; fig 4b
Abcam LMNA antibody (abcam, ab8980) was used in western blot on human samples at 1:2000 (fig 4b). Nat Cell Biol (2014) ncbi
mouse monoclonal (133A2)
  • western blot; human; 1:1000
Abcam LMNA antibody (Abcam, ab8980) was used in western blot on human samples at 1:1000. J Pharm Pharmacol (2014) ncbi
Invitrogen
mouse monoclonal (131C3)
  • immunocytochemistry; human; 1:200; loading ...; fig 4
In order to demonstrate that nuclear envelope rupture in cancer cells relies on the assembly of contractile actin bundles that interact with the nucleus via the linker of nucleoskeleton and cytoskeleton complex, Invitrogen LMNA antibody (Thermo Fischer Scientific, 131C3) was used in immunocytochemistry on human samples at 1:200 (fig 4). J Cell Biol (2016) ncbi
BD Biosciences
mouse monoclonal (14/LaminAC)
  • western blot; human; 1:1000; loading ...; fig 2g
BD Biosciences LMNA antibody (BD Biosciences, 612162) was used in western blot on human samples at 1:1000 (fig 2g). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (14/LaminAC)
  • western blot; human; loading ...; fig s1h
In order to study long noncoding RNA UPAT, colon tumorigenesis, and UHRF1, BD Biosciences LMNA antibody (BD Biosciences, 612162) was used in western blot on human samples (fig s1h). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (14/LaminAC)
  • western blot; human; fig 2
In order to assess negative regulation of the NF-kappaB-mediated signaling pathway through stabilization of Cactin by TRIM39, BD Biosciences LMNA antibody (BD Pharmingen, 612162) was used in western blot on human samples (fig 2). Cell Mol Life Sci (2016) ncbi
mouse monoclonal (14/LaminAC)
  • western blot; human
In order to study OGR1-mediated, pH-dependent signaling pathways in intestinal epithelial cells, BD Biosciences LMNA antibody (BD Biosciences, 612162) was used in western blot on human samples . Am J Physiol Gastrointest Liver Physiol (2015) ncbi
mouse monoclonal (14/LaminAC)
  • western blot; human; fig 6
BD Biosciences LMNA antibody (BD Biosciences, 612162) was used in western blot on human samples (fig 6). J Pathol (2014) ncbi
mouse monoclonal (14/LaminAC)
  • western blot; human
BD Biosciences LMNA antibody (BD Biosciences, 612162) was used in western blot on human samples . Neurobiol Dis (2014) ncbi
EMD Millipore
mouse monoclonal (14)
  • western blot; mouse; fig 7c
In order to study wound-associated epithelial cell differentiation, EMD Millipore LMNA antibody (EMD Millipore, 14) was used in western blot on mouse samples (fig 7c). EMBO J (2017) ncbi
mouse monoclonal (14)
  • western blot; human; fig 4
In order to investigate proteolytic processing of p27, EMD Millipore LMNA antibody (Millipore, clone14) was used in western blot on human samples (fig 4). Oncogene (2016) ncbi
mouse monoclonal (14)
  • immunohistochemistry; equine; 1:100; fig 2
  • immunohistochemistry; human; 1:100; fig 2
EMD Millipore LMNA antibody (Millipore, 05-714) was used in immunohistochemistry on equine samples at 1:100 (fig 2) and in immunohistochemistry on human samples at 1:100 (fig 2). Stem Cell Reports (2016) ncbi
mouse monoclonal (14)
  • immunocytochemistry; human
  • western blot; human
In order to study the mechanism through which the Bloom syndrome helicase suppresses homologous recombination at sites of DNA damage, EMD Millipore LMNA antibody (Upstate, 05-714) was used in immunocytochemistry on human samples and in western blot on human samples . EMBO J (2013) ncbi
Articles Reviewed
  1. Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam C, Garg P, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. 2019;572:335-340 pubmed publisher
  2. Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed publisher
  3. Zhang Y, Wang J, Huang W, Cai J, Ba J, Wang Y, et al. Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation. Nat Commun. 2018;9:3613 pubmed publisher
  4. Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
  5. Coccia M, Rossi A, Riccio A, Trotta E, Santoro M. Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance. Proc Natl Acad Sci U S A. 2017;114:1045-1050 pubmed publisher
  6. Miyoshi H, VanDussen K, Malvin N, Ryu S, Wang Y, Sonnek N, et al. Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium. EMBO J. 2017;36:5-24 pubmed publisher
  7. Hatch E, Hetzer M. Nuclear envelope rupture is induced by actin-based nucleus confinement. J Cell Biol. 2016;215:27-36 pubmed
  8. Wisnovsky S, Jean S, Kelley S. Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes. Nat Chem Biol. 2016;12:567-73 pubmed publisher
  9. Verhoeven R, Tong S, Zhang G, Zong J, Chen Y, Jin D, et al. NF-κB Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma. J Virol. 2016;90:6475-88 pubmed publisher
  10. Eisch V, Lu X, Gabriel D, Djabali K. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts. Oncotarget. 2016;7:24700-18 pubmed publisher
  11. Podmirseg S, Jäkel H, Ranches G, Kullmann M, Sohm B, Villunger A, et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene. 2016;35:4580-90 pubmed publisher
  12. Quattrocelli M, Giacomazzi G, Broeckx S, Ceelen L, Bolca S, Spaas J, et al. Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates. Stem Cell Reports. 2016;6:55-63 pubmed publisher
  13. Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, et al. Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proc Natl Acad Sci U S A. 2016;113:1273-8 pubmed publisher
  14. Dvash E, Har Tal M, Barak S, Meir O, Rubinstein M. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015;6:10112 pubmed publisher
  15. Safavi S, Järnum S, Vannas C, Udhane S, Jonasson E, Tomić T, et al. HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo. Oncotarget. 2016;7:433-45 pubmed publisher
  16. Suzuki M, Watanabe M, Nakamaru Y, Takagi D, Takahashi H, Fukuda S, et al. TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin. Cell Mol Life Sci. 2016;73:1085-101 pubmed publisher
  17. Chaumet A, Wright G, Seet S, Tham K, Gounko N, Bard F. Nuclear envelope-associated endosomes deliver surface proteins to the nucleus. Nat Commun. 2015;6:8218 pubmed publisher
  18. Matsui M, Li L, Janowski B, Corey D. Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors. Sci Rep. 2015;5:12855 pubmed publisher
  19. de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, et al. The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. Am J Physiol Gastrointest Liver Physiol. 2015;309:G475-90 pubmed publisher
  20. Yoon S, Bogdanov K, Kovalenko A, Wallach D. Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it. Cell Death Differ. 2016;23:253-60 pubmed publisher
  21. Cardona M, López J, Serafín A, Rongvaux A, Inserte J, García Dorado D, et al. Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart. PLoS ONE. 2015;10:e0131411 pubmed publisher
  22. Gong G, Chen P, Li L, Tan H, Zhou J, Zhou Y, et al. Loss of lamin A but not lamin C expression in epithelial ovarian cancer cells is associated with metastasis and poor prognosis. Pathol Res Pract. 2015;211:175-82 pubmed publisher
  23. Elkhatib R, Longepied G, Paci M, Achard V, Grillo J, Levy N, et al. Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform. Mol Hum Reprod. 2015;21:225-36 pubmed publisher
  24. Barbarin A, Séité P, Godet J, Bensalma S, Muller J, Chadéneau C. Atypical nuclear localization of VIP receptors in glioma cell lines and patients. Biochem Biophys Res Commun. 2014;454:524-30 pubmed publisher
  25. Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, et al. Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. J Pathol. 2014;234:302-15 pubmed publisher
  26. Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
  27. Dannoura A, Giraldo A, Pereira I, Gibbins J, Dash P, Bicknell K, et al. Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor ?. J Pharm Pharmacol. 2014;66:779-92 pubmed publisher
  28. Gómez Sánchez R, Gegg M, Bravo San Pedro J, Niso Santano M, Alvarez Erviti L, Pizarro Estrella E, et al. Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol Dis. 2014;62:426-40 pubmed publisher
  29. Tikoo S, Madhavan V, Hussain M, Miller E, Arora P, Zlatanou A, et al. Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination. EMBO J. 2013;32:1778-92 pubmed publisher