This is a Validated Antibody Database (VAD) review about dog JAK1, based on 15 published articles (read how Labome selects the articles), using JAK1 antibody in all methods. It is aimed to help Labome visitors find the most suited JAK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
JAK1 synonym: tyrosine-protein kinase JAK1; Janus kinase 1 (a protein tyrosine kinase); protein tyrosine kinase

Santa Cruz Biotechnology
mouse monoclonal (73)
  • western blot; human
Santa Cruz Biotechnology JAK1 antibody (Santa Cruz Biotechnology, sc- 136225) was used in western blot on human samples . Viral Immunol (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; rat
In order to investigate the role of ANGII in the regulation of latent and active MMP-2 in rat heart, Abcam JAK1 antibody (Abcam, ab125051) was used in western blot on rat samples . Basic Res Cardiol (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (6G4)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology JAK1 antibody (Cell Signaling, 6G4) was used in western blot on human samples at 1:1000 (fig 4a). Br J Cancer (2019) ncbi
rabbit monoclonal (6G4)
  • western blot; mouse; 1:500; loading ...; fig 4e
Cell Signaling Technology JAK1 antibody (Cell Signaling, 3344) was used in western blot on mouse samples at 1:500 (fig 4e). Nat Commun (2018) ncbi
rabbit monoclonal (6G4)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology JAK1 antibody (Cell signaling, 3344) was used in western blot on human samples (fig 3e). Nat Commun (2017) ncbi
rabbit monoclonal (6G4)
  • immunoprecipitation; mouse; loading ...; fig 4
  • western blot; mouse; loading ...; fig 4
In order to study mouse models of dilated cardiomyopathy to study calcium signaling, Cell Signaling Technology JAK1 antibody (Cell Signaling, 3344) was used in immunoprecipitation on mouse samples (fig 4) and in western blot on mouse samples (fig 4). PLoS ONE (2016) ncbi
rabbit monoclonal (6G4)
  • western blot; mouse; 1:2000; loading ...; fig 9a
Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3344) was used in western blot on mouse samples at 1:2000 (fig 9a). Drug Des Devel Ther (2016) ncbi
rabbit monoclonal (6G4)
  • western blot; mouse; fig 6c
Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 6G4) was used in western blot on mouse samples (fig 6c). J Exp Med (2016) ncbi
rabbit monoclonal (6G4)
  • western blot; human; loading ...; fig 4
Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 6G4) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
rabbit monoclonal (6G4)
  • western blot; human; fig 4
Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3344) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
rabbit monoclonal (6G4)
  • western blot; human; 1:1000; fig 4
In order to analyze multidrug resistant human cancer cells and autocrime cytokine/JAK/STAT-signaling induces kynurenin synthesis, Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3344) was used in western blot on human samples at 1:1000 (fig 4). PLoS ONE (2015) ncbi
rabbit monoclonal (6G4)
  • western blot; human
In order to show that uPAR regulates nasopharyngeal carcinoma NPC progression, Cell Signaling Technology JAK1 antibody (Cell Signaling Technology, 3344) was used in western blot on human samples . Cell Cycle (2014) ncbi
BD Biosciences
mouse monoclonal (73/JAK1)
  • western blot; human; 1:1000; loading ...; fig 3a
BD Biosciences JAK1 antibody (BD Biosciences, 610231) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
mouse monoclonal (73/JAK1)
  • western blot; mouse; loading ...; fig 3a
  • western blot; human; loading ...; fig 3f
BD Biosciences JAK1 antibody (BD Biosciences, 610231) was used in western blot on mouse samples (fig 3a) and in western blot on human samples (fig 3f). J Clin Invest (2016) ncbi
mouse monoclonal (73/JAK1)
  • western blot; human; 0.25 ug/mL
In order to evaluate the effect of JAK1/2 inhibitor AZD1480 on IL-6-induced experimental prostate cancer metastases formation, BD Biosciences JAK1 antibody (BD Biosciences, 610231) was used in western blot on human samples at 0.25 ug/mL. Mol Cancer Ther (2014) ncbi
Articles Reviewed
  1. Martin V, Chiriaco C, Modica C, Acquadro A, Cortese M, Galimi F, et al. Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours. Br J Cancer. 2019;120:527-536 pubmed publisher
  2. Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
  3. Cayrol F, Praditsuktavorn P, Fernando T, Kwiatkowski N, Marullo R, Calvo Vidal M, et al. THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors. Nat Commun. 2017;8:14290 pubmed publisher
  4. Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
  5. Ramratnam M, Salama G, Sharma R, Wang D, Smith S, Banerjee S, et al. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PLoS ONE. 2016;11:e0167681 pubmed publisher
  6. He Y, Yan Y, Zhang H, Lin Y, Chen Y, Yan Y, et al. Methyl salicylate 2-O-?-d-lactoside alleviates the pathological progression of pristane-induced systemic lupus erythematosus-like disease in mice via suppression of inflammatory response and signal transduction. Drug Des Devel Ther. 2016;10:3183-3196 pubmed
  7. Textor A, Schmidt K, Kloetzel P, Weißbrich B, Perez C, Charo J, et al. Preventing tumor escape by targeting a post-proteasomal trimming independent epitope. J Exp Med. 2016;213:2333-2348 pubmed
  8. Ma Y, Chen L, Xie G, Zhou Y, Yue C, Yuan X, et al. Elevated level of interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3. Oncotarget. 2016;7:73003-73015 pubmed publisher
  9. Yasuda T, Fukada T, Nishida K, Nakayama M, Matsuda M, Miura I, et al. Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. J Clin Invest. 2016;126:2064-76 pubmed publisher
  10. Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 2015;6:14796-813 pubmed
  11. Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, et al. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE. 2015;10:e0126159 pubmed publisher
  12. Kopaliani I, Martin M, Zatschler B, Bortlik K, Müller B, Deussen A. Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta. Basic Res Cardiol. 2014;109:419 pubmed publisher
  13. Liu Y, Zhang Z, Zhao X, Yu R, Zhang X, Wu S, et al. Enterovirus 71 inhibits cellular type I interferon signaling by downregulating JAK1 protein expression. Viral Immunol. 2014;27:267-76 pubmed publisher
  14. Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
  15. Gu L, Talati P, Vogiatzi P, Romero Weaver A, Abdulghani J, Liao Z, et al. Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation. Mol Cancer Ther. 2014;13:1246-58 pubmed publisher