This is a Validated Antibody Database (VAD) review about dog ITGA6, based on 26 published articles (read how Labome selects the articles), using ITGA6 antibody in all methods. It is aimed to help Labome visitors find the most suited ITGA6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ITGA6 synonym: integrin alpha-6; integrin, alpha 6

BioLegend
rat monoclonal (GoH3)
  • flow cytometry; human; loading ...; fig 9b
  • flow cytometry; mouse; loading ...; fig 2a
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples (fig 9b) and in flow cytometry on mouse samples (fig 2a). J Cell Biol (2018) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
BioLegend ITGA6 antibody (Biolegend, 313606) was used in immunohistochemistry on mouse samples at 1:100 (fig 4a). Nature (2018) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig s3c
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig s3c). J Clin Invest (2017) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 5a
In order to propose that macrophage-TNF-induced AKT/beta-catenin signaling in Lgr5(+) hair follicle stem cells is important for promoting hair follicle cycling and neogenesis after wounding, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in immunohistochemistry - frozen section on mouse samples at 1:150 (fig 5a). Nat Commun (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 3e
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 3e). Science (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; 1:25; loading ...; fig 3a
In order to define the interaction between LATS1/2 and the estrogen receptor signaling in breast cancer initiation., BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples at 1:25 (fig 3a). Nature (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig 2a
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 2a). Sci Rep (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 1a
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on mouse samples (fig 1a). PLoS Pathog (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; loading ...; fig 4
In order to discuss the relationship between TGF-beta and MYC in basal subtype breast cancers, BioLegend ITGA6 antibody (BioLegend, 313615) was used in flow cytometry on human samples (fig 4). Cancer Res (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; loading ...; tbl s1
In order to explore how junctional adhesion molecule family members differentially regulate CXCR4 function and CXCL12 secretion in the bone marrow niche, BioLegend ITGA6 antibody (Biolegend, 313618) was used in flow cytometry on human samples (tbl s1). Stem Cells (2016) ncbi
rat monoclonal (GoH3)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BioLegend ITGA6 antibody (BIOLegend, GoH3) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
rat monoclonal (GoH3)
  • immunohistochemistry; mouse; fig s1
In order to research skin-resident memory T cell homeostasis and lymphoma mediated by hair follicle-derived IL-7 and IL-15, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in immunohistochemistry on mouse samples (fig s1). Nat Med (2015) ncbi
rat monoclonal (GoH3)
  • western blot; human; 1:1000
BioLegend ITGA6 antibody (BioLegend, GoH3) was used in western blot on human samples at 1:1000. Hum Mol Genet (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig s6
BioLegend ITGA6 antibody (BioLegend, 313608) was used in flow cytometry on mouse samples (fig s6). Proc Natl Acad Sci U S A (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; fig 1
In order to study and identify critical cell lineage-dependent transduction bias to model breast cancer properly, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples (fig 1). Nat Commun (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; fig 5
In order to study the role of alpha-4 integrin in the mechanism by which CD82 modulates cell adhesion, BioLegend ITGA6 antibody (BioLegend, GoH3) was used in flow cytometry on human samples (fig 5). Mol Biol Cell (2014) ncbi
Bio-Rad
rat monoclonal (NKI-GoH3)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1b
Bio-Rad ITGA6 antibody (Serotec, NKI-GoH3) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1b). PLoS ONE (2017) ncbi
rat monoclonal (NKI-GoH3)
  • flow cytometry; mouse; 1:200; loading ...; fig 2a
In order to elucidate novel functions of the senescence-associated secretory in promoting a proregenerative response through the induction of cell plasticity and stemness, Bio-Rad ITGA6 antibody (Serotec, NKI-GoH3) was used in flow cytometry on mouse samples at 1:200 (fig 2a). Genes Dev (2017) ncbi
rat monoclonal (NKI-GoH3)
  • flow cytometry; human; loading ...; tbl 2
In order to assess the protective immunological events induced by vaccination with Leishmune in dogs, Bio-Rad ITGA6 antibody (AbD Serotec, MCA699PE) was used in flow cytometry on human samples (tbl 2). Vet Parasitol (2016) ncbi
rat monoclonal (NKI-GoH3)
  • blocking or activating experiments; mouse; fig s3
Bio-Rad ITGA6 antibody (AbD Serotec, MCA699EL) was used in blocking or activating experiments on mouse samples (fig s3). Sci Rep (2015) ncbi
rat monoclonal (NKI-GoH3)
  • immunohistochemistry - frozen section; mouse; 5 ug/ml
Bio-Rad ITGA6 antibody (Serotec, MCA699) was used in immunohistochemistry - frozen section on mouse samples at 5 ug/ml. J Comp Neurol (2007) ncbi
Invitrogen
rabbit monoclonal (5H14L18)
  • western blot; human; 1:250; loading ...; fig 2b
  • western blot; mouse; 1:250; loading ...; fig 1b
In order to ask if hypoxia-inducible factors modulate transcription of markers of breast cancer stem cells, Invitrogen ITGA6 antibody (Life Technologies, 701178) was used in western blot on human samples at 1:250 (fig 2b) and in western blot on mouse samples at 1:250 (fig 1b). Mol Cancer (2016) ncbi
BD Biosciences
rat monoclonal (GoH3)
  • flow cytometry; mouse; loading ...; fig 2b
BD Biosciences ITGA6 antibody (BD Pharmingen, GoH3) was used in flow cytometry on mouse samples (fig 2b). Oncotarget (2017) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; 1:100; loading ...; fig 3a
In order to study the role of RB1 in cancer cell proliferation., BD Biosciences ITGA6 antibody (BD, GoH3) was used in flow cytometry on human samples at 1:100 (fig 3a). J Clin Invest (2016) ncbi
rat monoclonal (GoH3)
  • flow cytometry; human; fig 3
In order to study promotion of collective invasion by an epigenetically distinct breast cancer cell subpopulation, BD Biosciences ITGA6 antibody (BD Biosciences, GoH3) was used in flow cytometry on human samples (fig 3). J Clin Invest (2015) ncbi
rat monoclonal (GoH3)
  • flow cytometry; mouse; fig s2
In order to study signaling pathways in tumor-resistant K5DeltaNbetacat mice, BD Biosciences ITGA6 antibody (BD Pharmingen, GoH3) was used in flow cytometry on mouse samples (fig s2). Oncogene (2014) ncbi
Articles Reviewed
  1. Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  2. Liakath Ali K, Mills E, Sequeira I, Lichtenberger B, Pisco A, Sipilä K, et al. An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis. Nature. 2018;556:376-380 pubmed publisher
  3. Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J. Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. PLoS ONE. 2017;12:e0186628 pubmed publisher
  4. Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody D, et al. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017;127:2339-2352 pubmed publisher
  5. Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  6. Zhao C, Cai S, Shin K, Lim A, Kalisky T, Lu W, et al. Stromal Gli2 activity coordinates a niche signaling program for mammary epithelial stem cells. Science. 2017;356: pubmed publisher
  7. Ritschka B, Storer M, Mas A, Heinzmann F, Ortells M, Morton J, et al. The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration. Genes Dev. 2017;31:172-183 pubmed publisher
  8. Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ER?. Nature. 2017;541:541-545 pubmed publisher
  9. Corbineau S, Lassalle B, Givelet M, Souissi Sarahoui I, Firlej V, Romeo P, et al. Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4. Oncotarget. 2017;8:10050-10063 pubmed publisher
  10. Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
  11. Jones R, Robinson T, Liu J, Shrestha M, Voisin V, Ju Y, et al. RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. J Clin Invest. 2016;126:3739-3757 pubmed publisher
  12. Quantius J, Schmoldt C, Vazquez Armendariz A, Becker C, El Agha E, Wilhelm J, et al. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair. PLoS Pathog. 2016;12:e1005544 pubmed publisher
  13. Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
  14. Brooks D, Schwab L, Krutilina R, Parke D, Sethuraman A, Hoogewijs D, et al. ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models. Mol Cancer. 2016;15:26 pubmed publisher
  15. Moreira M, Costa Pereira C, Alves M, Marteleto B, Ribeiro V, Peruhype Magalhães V, et al. Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes. Vet Parasitol. 2016;220:33-45 pubmed publisher
  16. Chang C, Hale S, Cox C, Blair A, Kronsteiner B, Grabowska R, et al. Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4. Stem Cells. 2016;34:1664-78 pubmed publisher
  17. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  18. Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed publisher
  19. Virts E, Jankowska A, MacKay C, Glaas M, Wiek C, Kelich S, et al. AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia. Hum Mol Genet. 2015;24:5093-108 pubmed publisher
  20. Davis F, Janoshazi A, Janardhan K, Steinckwich N, D Agostin D, Petranka J, et al. Essential role of Orai1 store-operated calcium channels in lactation. Proc Natl Acad Sci U S A. 2015;112:5827-32 pubmed publisher
  21. Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed publisher
  22. Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed publisher
  23. Arulmoli J, Pathak M, McDonnell L, Nourse J, Tombola F, Earthman J, et al. Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner. Sci Rep. 2015;5:8499 pubmed publisher
  24. Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed publisher
  25. Cagnet S, Faraldo M, Kreft M, Sonnenberg A, Raymond K, Glukhova M. Signaling events mediated by ?3?1 integrin are essential for mammary tumorigenesis. Oncogene. 2014;33:4286-95 pubmed publisher
  26. Davies D. Temporal and spatial regulation of alpha6 integrin expression during the development of the cochlear-vestibular ganglion. J Comp Neurol. 2007;502:673-82 pubmed