This is a Validated Antibody Database (VAD) review about dog INS, based on 16 published articles (read how Labome selects the articles), using INS antibody in all methods. It is aimed to help Labome visitors find the most suited INS antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
INS synonym: insulin

Sigma-Aldrich
mouse monoclonal (K36aC10)
  • immunohistochemistry; mouse; 1:250; fig 3c
Sigma-Aldrich INS antibody (Sigma, K36AC10) was used in immunohistochemistry on mouse samples at 1:250 (fig 3c). J Transl Med (2018) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s2b
Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry - paraffin section on mouse samples (fig s2b). J Clin Invest (2018) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; human; loading ...; fig 5a
Sigma-Aldrich INS antibody (Sigma, I 2018) was used in immunohistochemistry on human samples (fig 5a). Autoimmunity (2017) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; rat; 1:5000; loading ...; fig st9
In order to outline the protocols for antibodies used for immunohistochemical studies, Sigma-Aldrich INS antibody (Sigma-Aldrich, I2018) was used in immunohistochemistry - paraffin section on rat samples at 1:5000 (fig st9). J Toxicol Pathol (2017) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; rat; 1:1000; loading ...; fig s1a
In order to study the sensorial and affective behaviors and the locus coeruleus activity in diabetic rats, Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry on rat samples at 1:1000 (fig s1a). Prog Neuropsychopharmacol Biol Psychiatry (2016) ncbi
mouse monoclonal (K36aC10)
  • western blot; mouse; 1:1000; loading ...; fig 1e
Sigma-Aldrich INS antibody (Sigma-Aldrich, I2018) was used in western blot on mouse samples at 1:1000 (fig 1e). Diabetes (2015) ncbi
mouse monoclonal (K36aC10)
  • immunocytochemistry; human; 1:100; fig 6e
Sigma-Aldrich INS antibody (Sigma-Aldrich, I2018) was used in immunocytochemistry on human samples at 1:100 (fig 6e). Sci Rep (2014) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse
In order to investigate the role of nephrin in beta-cell survival signaling, Sigma-Aldrich INS antibody (Sigma-Aldrich, I 2018) was used in immunohistochemistry - paraffin section on mouse samples . Mol Cell Endocrinol (2015) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; human; 1:500
  • immunohistochemistry; mouse; 1:500
Sigma-Aldrich INS antibody (Sigma, I-2018) was used in immunohistochemistry on human samples at 1:500 and in immunohistochemistry on mouse samples at 1:500. Biochim Biophys Acta (2015) ncbi
mouse monoclonal (K36aC10)
  • immunocytochemistry; human; 1:100
Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunocytochemistry on human samples at 1:100. PLoS ONE (2014) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; rat; 1:1000
In order to localize dopamine receptors in the pancreatic islets of rats, Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry - paraffin section on rat samples at 1:1000. Cell Tissue Res (2014) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; rat; 1:1000
Sigma-Aldrich INS antibody (Sigma-Aldrich, I-2018) was used in immunohistochemistry - paraffin section on rat samples at 1:1000. Exp Mol Med (2013) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; 1:1000
Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000. Int J Physiol Pathophysiol Pharmacol (2013) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; 1:500
In order to study the roles of GATA4 and GATA6 in mouse pancreas organogenesis, Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry - paraffin section on mouse samples at 1:500. J Clin Invest (2012) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; rat; 1:200
Sigma-Aldrich INS antibody (Sigma, I2018) was used in immunohistochemistry - paraffin section on rat samples at 1:200. J Endocrinol (2011) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (GS-9A8)
  • immunohistochemistry - frozen section; human; fig 3
Developmental Studies Hybridoma Bank INS antibody (Developmental Studies Hybridoma Bank, GS-9A8) was used in immunohistochemistry - frozen section on human samples (fig 3). Nat Commun (2016) ncbi
Articles Reviewed
  1. Wang L, Sun Z, Xiang B, Wei C, Wang Y, Sun K, et al. Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance. J Transl Med. 2018;16:297 pubmed publisher
  2. Millership S, Da Silva Xavier G, Choudhury A, Bertazzo S, Chabosseau P, Pedroni S, et al. Neuronatin regulates pancreatic β cell insulin content and secretion. J Clin Invest. 2018;128:3369-3381 pubmed publisher
  3. Smith Anttila C, Bensing S, Alimohammadi M, Dalin F, Oscarson M, Zhang M, et al. Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1. Autoimmunity. 2017;50:223-231 pubmed publisher
  4. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  5. Dorrell C, Schug J, Canaday P, Russ H, Tarlow B, Grompe M, et al. Human islets contain four distinct subtypes of ? cells. Nat Commun. 2016;7:11756 pubmed publisher
  6. Alba Delgado C, Cebada Aleu A, Mico J, Berrocoso E. Comorbid anxiety-like behavior and locus coeruleus impairment in diabetic peripheral neuropathy: A comparative study with the chronic constriction injury model. Prog Neuropsychopharmacol Biol Psychiatry. 2016;71:45-56 pubmed publisher
  7. Han J, Song B, Kim J, Kodali V, Pottekat A, Wang M, et al. Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis. Diabetes. 2015;64:2892-904 pubmed publisher
  8. Pettinato G, Wen X, Zhang N. Formation of well-defined embryoid bodies from dissociated human induced pluripotent stem cells using microfabricated cell-repellent microwell arrays. Sci Rep. 2014;4:7402 pubmed publisher
  9. Kapodistria K, Tsilibary E, Politis P, Moustardas P, Charonis A, Kitsiou P. Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling. Mol Cell Endocrinol. 2015;400:112-28 pubmed publisher
  10. Aragón F, Karaca M, Novials A, Maldonado R, Maechler P, Rubí B. Pancreatic polypeptide regulates glucagon release through PPYR1 receptors expressed in mouse and human alpha-cells. Biochim Biophys Acta. 2015;1850:343-51 pubmed publisher
  11. Pettinato G, Vanden Berg Foels W, Zhang N, Wen X. ROCK inhibitor is not required for embryoid body formation from singularized human embryonic stem cells. PLoS ONE. 2014;9:e100742 pubmed publisher
  12. Chen Y, Hong F, Chen H, Fan R, Zhang X, Zhang Y, et al. Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats. Cell Tissue Res. 2014;357:597-606 pubmed publisher
  13. Oh T, Shin J, Kang G, Park K, Cho Y. Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats. Exp Mol Med. 2013;45:e30 pubmed publisher
  14. Feng M, Xiang Y, Wang S, Lu W. An autocrine ?-aminobutyric acid signaling system exists in pancreatic ?-cell progenitors of fetal and postnatal mice. Int J Physiol Pathophysiol Pharmacol. 2013;5:91-101 pubmed
  15. Carrasco M, Delgado I, Soria B, Martin F, Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 2012;122:3504-15 pubmed publisher
  16. Romero Zerbo S, Rafacho A, Diaz Arteaga A, Suarez J, Quesada I, Imbernon M, et al. A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. J Endocrinol. 2011;211:177-85 pubmed publisher