This is a Validated Antibody Database (VAD) review about dog HMOX1, based on 32 published articles (read how Labome selects the articles), using HMOX1 antibody in all methods. It is aimed to help Labome visitors find the most suited HMOX1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HMOX1 synonym: HO-1; Hsp32; heme oxygenase 1; heme oxygenase (decycling) 1

Knockout validation
StressMarq Biosciences
rabbit polyclonal
  • immunohistochemistry knockout validation; human; fig 6
StressMarq Biosciences HMOX1 antibody (StressMark Biosciences, SPC-112 C/D) was used in immunohistochemistry knockout validation on human samples (fig 6). Blood (2014) ncbi
Enzo Life Sciences
mouse monoclonal (HO-1-2)
  • flow cytometry; human; loading ...; fig 3b, 3e, 3h
Enzo Life Sciences HMOX1 antibody (Enzo, ADI-OSA-111FI) was used in flow cytometry on human samples (fig 3b, 3e, 3h). Cell Rep (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Enzo Life Sciences HMOX1 antibody (Stressgen, SPA-896) was used in western blot on mouse samples (fig 1b). Biochem Biophys Res Commun (2018) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 2a
Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, SPA-895(D)) was used in immunohistochemistry on mouse samples at 1:2000 (fig 2a). Endocrinology (2017) ncbi
mouse monoclonal (HO-1-1)
  • western blot; mouse; 1:2000; loading ...; fig 2b
  • western blot; human; 1:2000; loading ...; fig 7a
In order to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease, Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, OSA110) was used in western blot on mouse samples at 1:2000 (fig 2b) and in western blot on human samples at 1:2000 (fig 7a). Autophagy (2016) ncbi
mouse monoclonal (HO-1-2)
  • western blot; mouse; fig 2
Enzo Life Sciences HMOX1 antibody (Enzo, ADI-OSA-111) was used in western blot on mouse samples (fig 2). Antioxid Redox Signal (2017) ncbi
mouse monoclonal (HO-1-1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Enzo Life Sciences HMOX1 antibody (ENZO, HO-1-1) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Enzo Life Sciences HMOX1 antibody (Enzo, ADI-SPA-895-D) was used in western blot on human samples at 1:1000 (fig 3). Cell Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, ADI-SPA-895) was used in western blot on mouse samples at 1:2000. J Neurosci Res (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Enzo Life Sciences HMOX1 antibody (Enzo, ADI-SPA-895-D) was used in western blot on mouse samples at 1:1000. Free Radic Biol Med (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse
  • western blot; mouse
Enzo Life Sciences HMOX1 antibody (Enzo, ADI-SPA-896) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, SPA895) was used in western blot on human samples at 1:2000. Toxicol Sci (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 3c
Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, ADI-SPA-896) was used in immunohistochemistry - paraffin section on rat samples at 1:200 (fig 3c). J Biomed Mater Res B Appl Biomater (2015) ncbi
mouse monoclonal (HO-1-2)
  • western blot; mouse
Enzo Life Sciences HMOX1 antibody (Stressgen, OSA111) was used in western blot on mouse samples . Front Pharmacol (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:20,000
  • immunohistochemistry - frozen section; mouse; 1:1000
Enzo Life Sciences HMOX1 antibody (Stressgen Biotechnologies, SPA-895) was used in western blot on rat samples at 1:20,000 and in immunohistochemistry - frozen section on mouse samples at 1:1000. PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Enzo Life Sciences HMOX1 antibody (Enzo Life Science, SPA-896) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Enzo Life Sciences HMOX1 antibody (Enzo Life Sciences, ADI-SPA-896-D) was used in western blot on mouse samples . Am J Physiol Renal Physiol (2013) ncbi
Abcam
mouse monoclonal (HO-1-1)
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig s5c
Abcam HMOX1 antibody (Abcam, ab13248) was used in immunohistochemistry - frozen section on mouse samples at 1:300 (fig s5c). Atherosclerosis (2019) ncbi
mouse monoclonal (HO-1-1)
  • immunohistochemistry; human; 1:100; loading ...; fig 1
Abcam HMOX1 antibody (Abcam, ab13248) was used in immunohistochemistry on human samples at 1:100 (fig 1). Cell Rep (2018) ncbi
mouse monoclonal (HO-1-1)
  • western blot; pig; 1:250; loading ...; fig 8b
In order to use CRISPR/Cas9 to generate pigs with a deletion of Exon 7 of the CD163 gene, encoding the scavenger receptor cysteine-rich domain 5, Abcam HMOX1 antibody (Abcam, ab13248) was used in western blot on pig samples at 1:250 (fig 8b). PLoS Pathog (2017) ncbi
mouse monoclonal (HO-1-1)
  • western blot; human; 1:250; loading ...; fig 6b
In order to test if the Keap1-SQSTM1 interaction increases Nrf2 signaling in autophagic vacuolar myopathies, Abcam HMOX1 antibody (Abcam, ab13248) was used in western blot on human samples at 1:250 (fig 6b). Acta Neuropathol Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 6c
Abcam HMOX1 antibody (Abcam, ab13243) was used in western blot on mouse samples at 1:2000 (fig 6c). Toxicol Appl Pharmacol (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:2000; fig 1
Abcam HMOX1 antibody (Abcam, ab13243) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 1). Acta Neuropathol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 4 ug/ml; fig 3
  • western blot; rat; fig 3
Abcam HMOX1 antibody (Abcam, ab13243) was used in immunohistochemistry - paraffin section on rat samples at 4 ug/ml (fig 3) and in western blot on rat samples (fig 3). Free Radic Biol Med (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat
  • western blot; rat
Abcam HMOX1 antibody (Abcam, ab13243) was used in immunohistochemistry - paraffin section on rat samples and in western blot on rat samples . Sci Rep (2014) ncbi
rabbit polyclonal
  • western blot; human
Abcam HMOX1 antibody (Abcam, ab13243) was used in western blot on human samples . Environ Sci Technol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000
Abcam HMOX1 antibody (Abcam, ab13243) was used in western blot on mouse samples at 1:2000. Toxicology (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:2000; fig 3b
Abcam HMOX1 antibody (Abcam, ab13243) was used in western blot on mouse samples at 1:2000 (fig 3b). Food Chem Toxicol (2013) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam HMOX1 antibody (Abcam, Ab13243) was used in western blot on mouse samples . Mol Ther (2013) ncbi
Invitrogen
mouse monoclonal (HO-1-1)
  • immunocytochemistry; human; 1:100; fig s7b
  • western blot; human; fig 3b
In order to investigate the involvement of OSGIN1 in smoking-induced autophagy in the airway epithelium, Invitrogen HMOX1 antibody (Thermo Fisher Scientific, MA1-112) was used in immunocytochemistry on human samples at 1:100 (fig s7b) and in western blot on human samples (fig 3b). Autophagy (2017) ncbi
mouse monoclonal (HO-1-1)
  • western blot; rat; loading ...; fig 4a
In order to elucidate the effects of baicalin in an infant rodent model of pulmonary hypertension, Invitrogen HMOX1 antibody (Invitrogen, MA1-112) was used in western blot on rat samples (fig 4a). FEBS Open Bio (2017) ncbi
mouse monoclonal (HO-1-1)
  • western blot; mouse; 1:500; fig 5a
In order to assess the anti-fatigue effects of Myelophil, Invitrogen HMOX1 antibody (Thermo Fisher, MA1-112) was used in western blot on mouse samples at 1:500 (fig 5a). Eur J Pharmacol (2015) ncbi
mouse monoclonal (HO-1-1)
  • western blot; mouse; 1:500
In order to evaluate the anti-fatigue effects of Gongjin-Dan in a chronic forced exercise mouse model, Invitrogen HMOX1 antibody (Thermo Fisher, MA1-112) was used in western blot on mouse samples at 1:500. J Ethnopharmacol (2015) ncbi
StressMarq Biosciences
rabbit polyclonal
  • immunohistochemistry knockout validation; human; fig 6
StressMarq Biosciences HMOX1 antibody (StressMark Biosciences, SPC-112 C/D) was used in immunohistochemistry knockout validation on human samples (fig 6). Blood (2014) ncbi
Articles Reviewed
  1. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  2. Chinta K, Rahman M, Saini V, Glasgow J, Reddy V, Lever J, et al. Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis. Cell Rep. 2018;25:1938-1952.e5 pubmed publisher
  3. Inouye S, Hatori Y, Kubo T, Saito S, Kitamura H, Akagi R. NRF2 and HSF1 coordinately regulate heme oxygenase-1 expression. Biochem Biophys Res Commun. 2018;506:7-11 pubmed publisher
  4. Wang G, Zhou H, Strulovici Barel Y, Al Hijji M, Ou X, Salit J, et al. Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. Autophagy. 2017;13:1205-1220 pubmed publisher
  5. Chen Z, Wang Q. Activation of PPAR? by baicalin attenuates pulmonary hypertension in an infant rat model by suppressing HMGB1/RAGE signaling. FEBS Open Bio. 2017;7:477-484 pubmed publisher
  6. Ghosh A, Abdo S, Zhao S, Wu C, Shi Y, Lo C, et al. Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice. Endocrinology. 2017;158:903-919 pubmed publisher
  7. Burkard C, Lillico S, Reid E, Jackson B, Mileham A, Ait Ali T, et al. Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function. PLoS Pathog. 2017;13:e1006206 pubmed publisher
  8. Duleh S, Wang X, Komirenko A, Margeta M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol Commun. 2016;4:115 pubmed
  9. Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
  10. Wang Y, Chen M, Zhang Y, Huo T, Fang Y, Jiao X, et al. Effects of realgar on GSH synthesis in the mouse hippocampus: Involvement of system XAG(-), system XC(-), MRP-1 and Nrf2. Toxicol Appl Pharmacol. 2016;308:91-101 pubmed publisher
  11. Belcher J, Chen C, Nguyen J, Zhang P, Abdulla F, Nguyen P, et al. Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate. Antioxid Redox Signal. 2017;26:748-762 pubmed publisher
  12. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  13. Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed publisher
  14. Barone E, Cenini G, Di Domenico F, Noel T, Wang C, Perluigi M, et al. Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53. J Neurosci Res. 2015;93:1728-39 pubmed publisher
  15. Lee J, Kim H, Han J, Kim Y, Son C. Anti-fatigue effect of Myelophil in a chronic forced exercise mouse model. Eur J Pharmacol. 2015;764:100-8 pubmed publisher
  16. Licht Mayer S, Wimmer I, Traffehn S, Metz I, Brück W, Bauer J, et al. Cell type-specific Nrf2 expression in multiple sclerosis lesions. Acta Neuropathol. 2015;130:263-77 pubmed publisher
  17. Hong S, Lee J, Lee J, Lee H, Kim H, Lee S, et al. The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model. J Ethnopharmacol. 2015;168:268-78 pubmed publisher
  18. Irwin D, Baek J, Hassell K, Nuss R, Eigenberger P, Lisk C, et al. Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration. Free Radic Biol Med. 2015;82:50-62 pubmed publisher
  19. Chang A, Ulrich A, Suliman H, Piantadosi C. Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. Free Radic Biol Med. 2015;78:179-89 pubmed publisher
  20. Ding Y, Chen M, Wang M, Wang M, Zhang T, Park J, et al. Neuroprotection by acetyl-11-keto-β-Boswellic acid, in ischemic brain injury involves the Nrf2/HO-1 defense pathway. Sci Rep. 2014;4:7002 pubmed publisher
  21. Wang S, Zheng W, Liu X, Xue P, Jiang S, Lu D, et al. Iodoacetic acid activates Nrf2-mediated antioxidant response in vitro and in vivo. Environ Sci Technol. 2014;48:13478-88 pubmed publisher
  22. Biswas C, Shah N, Muthu M, La P, Fernando A, Sengupta S, et al. Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses. J Biol Chem. 2014;289:26882-94 pubmed publisher
  23. Domitrovic R, Cvijanovic O, Susnić V, Katalinić N. Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury. Toxicology. 2014;324:98-107 pubmed publisher
  24. Wen X, Gibson C, Yang I, Buckley B, Goedken M, Richardson J, et al. MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells. Toxicol Sci. 2014;141:475-83 pubmed publisher
  25. Kovtunovych G, Ghosh M, Ollivierre W, Weitzel R, Eckhaus M, Tisdale J, et al. Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice. Blood. 2014;124:1522-30 pubmed publisher
  26. Bhattarai G, Lee Y, Yi H. Peroxisome proliferator activated receptor gamma loaded dental implant improves osteogenesis of rat mandible. J Biomed Mater Res B Appl Biomater. 2015;103:587-95 pubmed publisher
  27. Vercellotti G, Khan F, Nguyen J, Chen C, Bruzzone C, Bechtel H, et al. H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice. Front Pharmacol. 2014;5:79 pubmed publisher
  28. Yamashita Y, Ueyama T, Nishi T, Yamamoto Y, Kawakoshi A, Sunami S, et al. Nrf2-inducing anti-oxidation stress response in the rat liver--new beneficial effect of lansoprazole. PLoS ONE. 2014;9:e97419 pubmed publisher
  29. Namba F, Go H, Murphy J, La P, Yang G, Sengupta S, et al. Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model. PLoS ONE. 2014;9:e90936 pubmed publisher
  30. Domitrovic R, Cvijanovic O, Pernjak Pugel E, Skoda M, Mikelić L, Crncevic Orlic Z. Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis. Food Chem Toxicol. 2013;62:397-406 pubmed publisher
  31. Liu Y, Jia Z, Liu S, Downton M, Liu G, Du Y, et al. Combined losartan and nitro-oleic acid remarkably improves diabetic nephropathy in mice. Am J Physiol Renal Physiol. 2013;305:F1555-62 pubmed publisher
  32. Nanou A, Higginbottom A, Valori C, Wyles M, Ning K, Shaw P, et al. Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis. Mol Ther. 2013;21:1486-96 pubmed publisher