This is a Validated Antibody Database (VAD) review about dog HDAC2, based on 11 published articles (read how Labome selects the articles), using HDAC2 antibody in all methods. It is aimed to help Labome visitors find the most suited HDAC2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
HDAC2 synonym: histone deacetylase 2

Abcam
mouse monoclonal (HDAC2-62)
  • chromatin immunoprecipitation; mouse; loading ...; fig 4a
Abcam HDAC2 antibody (Abcam, ab12169) was used in chromatin immunoprecipitation on mouse samples (fig 4a). Nat Commun (2018) ncbi
mouse monoclonal (HDAC2-62)
  • chromatin immunoprecipitation; human; loading ...; fig s4b
  • western blot; human; 1:100; loading ...; fig 3a
Abcam HDAC2 antibody (Abcam, ab12169) was used in chromatin immunoprecipitation on human samples (fig s4b) and in western blot on human samples at 1:100 (fig 3a). Nat Commun (2018) ncbi
mouse monoclonal (HDAC2-62)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6b
In order to investigate the role of lysine specific demethylase 1 in neuronal maturation in the olfactory system, Abcam HDAC2 antibody (Abcam, ab12169) was used in immunohistochemistry - frozen section on mouse samples (fig 6b). J Comp Neurol (2017) ncbi
mouse monoclonal (HDAC2-62)
  • ChIP-Seq; human; loading ...; fig s5o
  • western blot; human; loading ...; fig s5l
In order to demonstrate that iPS-derived cardiomyocytes with a heterozygous GATA4-G296S missense mutation show impaired contractility, calcium handling, and metabolic activity, Abcam HDAC2 antibody (Abcam, ab12169) was used in ChIP-Seq on human samples (fig s5o) and in western blot on human samples (fig s5l). Cell (2016) ncbi
mouse monoclonal (HDAC2-62)
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to examine the effect of piceatannol on renal fibrosis and histone deacetylase expression in a mouse model of unilateral ureteral obstruction, Abcam HDAC2 antibody (Abcam, ab12169) was used in western blot on mouse samples at 1:1000 (fig 6a). PLoS ONE (2016) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 2c
In order to suggest that the use of HDAC inhibitors in a context of acquired glucocorticoid resistance may modify the epigenetic landscape, Invitrogen HDAC2 antibody (Thermo Scientific, PA1-861) was used in western blot on human samples at 1:2000 (fig 2c). Int J Oncol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:3000; fig 7
In order to test nuclear LC3 and how it associates with slowly diffusing complexes that interact with the nucleolus, Invitrogen HDAC2 antibody (Thermo Scientific, PA1-861) was used in western blot on human samples at 1:3000 (fig 7). Traffic (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to study the mechanism by which SFMBT1 modulates epigenetic silencing and mitogenic gene expression, Invitrogen HDAC2 antibody (Thermo, PA1-861) was used in western blot on human samples . J Biol Chem (2013) ncbi
Enzo Life Sciences
rabbit polyclonal
  • immunocytochemistry; human
In order to study the inhibitory effect of hypoxia on gene transcription and its mechanism, Enzo Life Sciences HDAC2 antibody (BIOMOL, SA-402) was used in immunocytochemistry on human samples . Nucleic Acids Res (2014) ncbi
Sigma-Aldrich
mouse monoclonal (HDAC2-62)
  • chromatin immunoprecipitation; mouse; fig 6b
  • western blot; mouse; 1:1000; loading ...; fig 1a
Sigma-Aldrich HDAC2 antibody (Sigma, H2663) was used in chromatin immunoprecipitation on mouse samples (fig 6b) and in western blot on mouse samples at 1:1000 (fig 1a). Nat Commun (2017) ncbi
mouse monoclonal (HDAC2-62)
  • immunohistochemistry - paraffin section; mouse; fig 1c
In order to determine the functional role of HDAC1 and HDAC2 in an acute model of optic nerve injury, Sigma-Aldrich HDAC2 antibody (Sigma, H2663) was used in immunohistochemistry - paraffin section on mouse samples (fig 1c). ASN Neuro (2015) ncbi
Articles Reviewed
  1. Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed publisher
  2. Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  3. Coleman J, Lin B, Schwob J. Dissecting LSD1-Dependent Neuronal Maturation in the Olfactory Epithelium. J Comp Neurol. 2017;525:3391-3413 pubmed publisher
  4. Brügger V, Duman M, Bochud M, Münger E, Heller M, Ruff S, et al. Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nat Commun. 2017;8:14272 pubmed publisher
  5. Hentati Kallel M, Le Jan S, Bernard P, Antonicelli F, Trussardi Regnier A. Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. Int J Oncol. 2017;50:717-726 pubmed publisher
  6. Ang Y, Rivas R, Ribeiro A, Srivas R, Rivera J, Stone N, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016;167:1734-1749.e22 pubmed publisher
  7. Choi S, Piao Z, Jin L, Kim J, Kim G, Ryu Y, et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS ONE. 2016;11:e0167340 pubmed publisher
  8. Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed publisher
  9. Lebrun Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
  10. Safronova O, Nakahama K, Morita I. Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression. Nucleic Acids Res. 2014;42:8954-69 pubmed publisher
  11. Lin S, Shen H, Li J, Tang S, Gu Y, Chen Z, et al. Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program. J Biol Chem. 2013;288:6238-47 pubmed publisher