This is a Validated Antibody Database (VAD) review about dog GSK3A, based on 33 published articles (read how Labome selects the articles), using GSK3A antibody in all methods. It is aimed to help Labome visitors find the most suited GSK3A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GSK3A synonym: glycogen synthase kinase-3 alpha

Knockout validation
BD Biosciences
mouse monoclonal (7/GSK-3b)
  • western blot knockout validation; mouse; 1:1000; fig 1a
BD Biosciences GSK3A antibody (BD, 610201) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1a). Dev Cell (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (0011-A)
  • other; human; loading ...; fig 4c
Santa Cruz Biotechnology GSK3A antibody (SantaCruz, sc-7291) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (0011-A)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, SC-7291) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (0011-A)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Santa Cruz Biotechnology GSK3A antibody (SantaCruz, SC-7291) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (0011-A)
  • western blot; human; 1:500; loading ...; fig 3b
In order to show that quercetin inhibits the PI3K/AKT/mTOR and STAT3 pathways in primary effusion lymphoma, Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in western blot on human samples at 1:500 (fig 3b). J Nutr Biochem (2017) ncbi
mouse monoclonal (0011-A)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in western blot on human samples . Cell Syst (2017) ncbi
mouse monoclonal (0011-A)
  • western blot; human; 1:200; fig 8e
Santa Cruz Biotechnology GSK3A antibody (santa cruz, sc-7291) was used in western blot on human samples at 1:200 (fig 8e). J Biol Chem (2015) ncbi
mouse monoclonal (0011-A)
  • immunocytochemistry; Chlamydomonas reinhardtii; 1:100; fig 5
  • ELISA; Chlamydomonas reinhardtii; 1:500; fig 5
  • western blot; Chlamydomonas reinhardtii; 1:500; fig 5
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in immunocytochemistry on Chlamydomonas reinhardtii samples at 1:100 (fig 5), in ELISA on Chlamydomonas reinhardtii samples at 1:500 (fig 5) and in western blot on Chlamydomonas reinhardtii samples at 1:500 (fig 5). Mol Biol Cell (2015) ncbi
mouse monoclonal (0011-A)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz Biotechnology, sc-7291) was used in western blot on mouse samples at 1:1000. Psychiatry Res (2015) ncbi
mouse monoclonal (0011-A)
  • western blot; human; fig 2
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz Biotechnology, sc7291) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (0011-A)
  • western blot; human
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz Biotechnology, sc-7291) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (0011-A)
  • western blot; mouse
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in western blot on mouse samples . J Biol Rhythms (2014) ncbi
mouse monoclonal (0011-A)
  • western blot; mouse; fig 2a
Santa Cruz Biotechnology GSK3A antibody (Santa, sc-7291) was used in western blot on mouse samples (fig 2a). Cell Res (2014) ncbi
mouse monoclonal (0011-A)
  • western blot; human
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (0011-A)
  • western blot; human
In order to investigate the role of asymmetric cell division during tumorigenesis, Santa Cruz Biotechnology GSK3A antibody (Santa Cruz Biotechnology, sc-7291) was used in western blot on human samples . Cancer Res (2014) ncbi
mouse monoclonal (0011-A)
  • western blot; human; fig 5
Santa Cruz Biotechnology GSK3A antibody (Santa Cruz, sc-7291) was used in western blot on human samples (fig 5). Cell (2014) ncbi
BD Biosciences
mouse monoclonal (7/GSK-3b)
  • western blot knockout validation; mouse; 1:1000; fig 1a
BD Biosciences GSK3A antibody (BD, 610201) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1a). Dev Cell (2017) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human; loading ...; fig 7b
  • western blot; mouse; loading ...; fig 8c
  • western blot; rat; loading ...; fig 7b
BD Biosciences GSK3A antibody (BD Biosciences, 7) was used in western blot on human samples (fig 7b), in western blot on mouse samples (fig 8c) and in western blot on rat samples (fig 7b). Am J Physiol Gastrointest Liver Physiol (2016) ncbi
mouse monoclonal (7/GSK-3b)
  • immunohistochemistry; mouse; 1:500; fig 5d
BD Biosciences GSK3A antibody (BD Biosciences, 610201) was used in immunohistochemistry on mouse samples at 1:500 (fig 5d). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse; fig s6
In order to assess the inhibition of mammalian target of rapamycin complex 1 in mice due to fibroblast growth factor 21 improving hepatic insulin sensitivity, BD Biosciences GSK3A antibody (BD Biosciences, 610202) was used in western blot on mouse samples (fig s6). Hepatology (2016) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; rat; 1:2500; fig 4b
BD Biosciences GSK3A antibody (BD, 610201) was used in western blot on rat samples at 1:2500 (fig 4b). Neural Plast (2016) ncbi
mouse monoclonal (7/GSK-3b)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences GSK3A antibody (BD, 7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human; loading ...; fig 4a
BD Biosciences GSK3A antibody (BD, 610202) was used in western blot on human samples (fig 4a). Oncotarget (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human; 1:250; fig 6
In order to characterize two clones from triple negative breast MDA-MB-231 cancer cells, BD Biosciences GSK3A antibody (BD Transduction Laboratories, 610201) was used in western blot on human samples at 1:250 (fig 6). Exp Cell Res (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • immunocytochemistry; mouse; 1:200; fig 3
In order to assess dendritic spine structural plasticity and requirement for GSK3-alpha and GSK3-beta, BD Biosciences GSK3A antibody (BD, 610201) was used in immunocytochemistry on mouse samples at 1:200 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human; fig 3
BD Biosciences GSK3A antibody (BD Transduction, 610201) was used in western blot on human samples (fig 3). EMBO J (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse; 1:1000; fig 6
BD Biosciences GSK3A antibody (BD Sciences, 610201) was used in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse
In order to elucidate the role of farnesylation in burn-induced metabolic aberration, BD Biosciences GSK3A antibody (BD Bioscience, 610202) was used in western blot on mouse samples . PLoS ONE (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse
In order to investigate the interactions between Abeta1-42 and Abeta1-40, BD Biosciences GSK3A antibody (BD Sciences, 610201) was used in western blot on mouse samples . Mol Neurodegener (2014) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse; fig 8
In order to characterize how insulin resistance is induced and alteration of substrate utilization in vivo due to acute mTOR inhibition, BD Biosciences GSK3A antibody (BD Bioscience, 610201) was used in western blot on mouse samples (fig 8). Mol Metab (2014) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse
In order to study the effect of ankyrin-G on neurogenesis and Wnt signaling and its mechanism, BD Biosciences GSK3A antibody (BD Transduction, 610202) was used in western blot on mouse samples . Mol Psychiatry (2015) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human
In order to study the effect of SB216763 on mitochondrial biogenesis, BD Biosciences GSK3A antibody (BD Bioscience, 610202) was used in western blot on human samples . Mitochondrion (2014) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; mouse; 1:1000
BD Biosciences GSK3A antibody (BD Transduction Laboratories, 610 201) was used in western blot on mouse samples at 1:1000. Nucleic Acids Res (2012) ncbi
mouse monoclonal (7/GSK-3b)
  • western blot; human
BD Biosciences GSK3A antibody (BD Transduction Laboratories, 610201) was used in western blot on human samples . J Neurochem (2008) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed publisher
  3. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  4. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  5. Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed publisher
  6. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  7. Nasri I, Bonnet D, Zwarycz B, d Aldebert E, Khou S, Mezghani Jarraya R, et al. PAR2-dependent activation of GSK3? regulates the survival of colon stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2016;311:G221-36 pubmed publisher
  8. Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed publisher
  9. Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed publisher
  10. Molteni R, Rossetti A, Savino E, Racagni G, Calabrese F. Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices. Neural Plast. 2016;2016:2592319 pubmed publisher
  11. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  12. Lin K, Kao S, Lai C, Chen C, Wu C, Hsu H, et al. Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3. J Biol Chem. 2015;290:29808-19 pubmed publisher
  13. Hausmann C, Temme A, Cordes N, Eke I. ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. Oncotarget. 2015;6:34592-605 pubmed publisher
  14. Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher
  15. Kong J, Hardin K, Dinkins M, Wang G, He Q, Mujadzic T, et al. Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3. Mol Biol Cell. 2015;26:4451-65 pubmed publisher
  16. Seo M, Lee C, Cho H, You Y, Lee B, Lee J, et al. Effects of antipsychotic drugs on the expression of synapse-associated proteins in the frontal cortex of rats subjected to immobilization stress. Psychiatry Res. 2015;229:968-74 pubmed publisher
  17. Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J. Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β. PLoS ONE. 2015;10:e0134018 pubmed publisher
  18. Reis C, Chen P, Srinivasan S, Aguet F, Mettlen M, Schmid S. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 2015;34:2132-46 pubmed publisher
  19. Kim A, Park Y, Pan X, Shin K, Kwak S, Bassas A, et al. Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance. Nat Commun. 2015;6:7585 pubmed publisher
  20. Morra F, Luise C, Merolla F, Poser I, Visconti R, Ilardi G, et al. FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC. Oncotarget. 2015;6:12697-709 pubmed
  21. Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu Y, Fischman A, et al. Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle. PLoS ONE. 2015;10:e0116633 pubmed publisher
  22. Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
  23. Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S. Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40. Mol Neurodegener. 2014;9:52 pubmed publisher
  24. Young M, Brewer R, Peliciari Garcia R, Collins H, He L, Birky T, et al. Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart. J Biol Rhythms. 2014;29:257-76 pubmed publisher
  25. Chu Y, Gómez Rosso L, Huang P, Wang Z, Xu Y, Yao X, et al. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. 2014;24:1250-65 pubmed publisher
  26. Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
  27. Xu L, Long Z, Peng F, Liu Y, Xu J, Wang C, et al. Aurora kinase a suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells. Oncotarget. 2014;5:7498-511 pubmed
  28. Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed publisher
  29. Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed publisher
  30. Durak O, de Anda F, Singh K, Leussis M, Petryshen T, Sklar P, et al. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of ?-catenin. Mol Psychiatry. 2015;20:388-97 pubmed publisher
  31. Ngamsiri P, Watcharasit P, Satayavivad J. Glycogen synthase kinase-3 (GSK3) controls deoxyglucose-induced mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells. Mitochondrion. 2014;14:54-63 pubmed publisher
  32. Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed publisher
  33. Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed publisher