This is a Validated Antibody Database (VAD) review about dog GGA3, based on 27 published articles (read how Labome selects the articles), using GGA3 antibody in all methods. It is aimed to help Labome visitors find the most suited GGA3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GGA3 synonym: ADP-ribosylation factor-binding protein GGA3

Knockout validation
BD Biosciences
mouse monoclonal (8/Adaptin)
  • western blot knockout validation; human; loading ...
BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in western blot knockout validation on human samples . elife (2019) ncbi
BD Biosciences
mouse monoclonal (8/Adaptin)
  • western blot knockout validation; human; loading ...
BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in western blot knockout validation on human samples . elife (2019) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human; 1:200; loading ...; fig s2d
BD Biosciences GGA3 antibody (BD Bioscience, 610386) was used in immunocytochemistry on human samples at 1:200 (fig s2d). J Cell Sci (2019) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:500; loading ...; fig s3c
  • immunoprecipitation; mouse; 1:1000; loading ...; fig 2a
  • immunocytochemistry; mouse; 1:500; loading ...; fig 6c
  • western blot; mouse; 1:500; loading ...; fig 2a
BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in western blot on human samples at 1:500 (fig s3c), in immunoprecipitation on mouse samples at 1:1000 (fig 2a), in immunocytochemistry on mouse samples at 1:500 (fig 6c) and in western blot on mouse samples at 1:500 (fig 2a). Nat Commun (2017) ncbi
mouse monoclonal (88/Adaptin)
  • immunoprecipitation; mouse; 1:1000; loading ...; fig s3b
  • western blot; mouse; 1:1000; loading ...; fig s3b
BD Biosciences GGA3 antibody (BD Biosciences, 610386) was used in immunoprecipitation on mouse samples at 1:1000 (fig s3b) and in western blot on mouse samples at 1:1000 (fig s3b). Nat Commun (2017) ncbi
mouse monoclonal (74/Adaptin)
  • western blot; human; 1:1000; loading ...; fig s14b
In order to examine haploinsufficiency network analyses to identify which somatic copy-number alteration patterns are most disruptive in ovarian cancer, BD Biosciences GGA3 antibody (BD, 610382) was used in western blot on human samples at 1:1000 (fig s14b). Nat Commun (2017) ncbi
mouse monoclonal (88/Adaptin)
  • immunohistochemistry - frozen section; mouse; fig 7e
  • immunohistochemistry; mouse; fig s4d
BD Biosciences GGA3 antibody (BD Transduction Laboratories, 610386) was used in immunohistochemistry - frozen section on mouse samples (fig 7e) and in immunohistochemistry on mouse samples (fig s4d). Cell Death Dis (2017) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; mouse; fig 4
BD Biosciences GGA3 antibody (BD, 610386) was used in western blot on mouse samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
In order to propose that ikarugamycin is a useful reagent to study routes of endocytic trafficking, BD Biosciences GGA3 antibody (BD Pharmingen, 610385) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 4b). Traffic (2016) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; human; fig s1
BD Biosciences GGA3 antibody (BD Bioscience, 610386) was used in western blot on human samples (fig s1). BMC Biol (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; human; fig 3
  • western blot; human; 1:1000; fig 3
BD Biosciences GGA3 antibody (BD Biosciences, 610382) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples at 1:1000 (fig 3). Drug Des Devel Ther (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; African green monkey; 1:1000; fig s1
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, BD Biosciences GGA3 antibody (BD Biosciences, 610382) was used in immunocytochemistry on African green monkey samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; fig 6
BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in western blot on human samples at 1:1000 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; fig 2
BD Biosciences GGA3 antibody (BD Transduction Laboratories, 610502) was used in western blot on human samples at 1:1000 (fig 2). elife (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; mouse
BD Biosciences GGA3 antibody (BD-Bioscience, 610502) was used in western blot on mouse samples . J Lipid Res (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; mouse; fig s4
  • western blot; mouse; fig s4
BD Biosciences GGA3 antibody (BD, 610381) was used in immunocytochemistry on mouse samples (fig s4) and in western blot on mouse samples (fig s4). Sci Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; mouse; 1:100; fig 5a
  • western blot; mouse; fig 1
In order to determine the affects of dendritic cell migration in vitro by loss of gadkin, BD Biosciences GGA3 antibody (BD Biosciences, 610386) was used in immunocytochemistry on mouse samples at 1:100 (fig 5a) and in western blot on mouse samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; rat; fig 1
In order to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11, BD Biosciences GGA3 antibody (BD Transduction Laboratories, 610501) was used in western blot on rat samples (fig 1). EMBO Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; rat; 1:5000
In order to localize ADAM10 and BACE1 in synaptic vesicles, BD Biosciences GGA3 antibody (BD Biosciences, 610386) was used in western blot on rat samples at 1:5000. J Neurochem (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunohistochemistry - paraffin section; mouse; fig 4,5
In order to study the role of excitotoxicity in neuronal death, BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in immunohistochemistry - paraffin section on mouse samples (fig 4,5). J Neurosci (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunocytochemistry; mouse
BD Biosciences GGA3 antibody (BD Pharmingen, 610502) was used in immunocytochemistry on mouse samples . Med Microbiol Immunol (2015) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; fig s1f
  • immunocytochemistry; African green monkey; fig s2d
In order to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis, BD Biosciences GGA3 antibody (BD, 610501) was used in western blot on human samples (fig s1f) and in immunocytochemistry on African green monkey samples (fig s2d). Nature (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunohistochemistry - paraffin section; mouse; 1:800; fig 4
BD Biosciences GGA3 antibody (BD Transduction Lab, 610501) was used in immunohistochemistry - paraffin section on mouse samples at 1:800 (fig 4). PLoS ONE (2014) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; loading ...; fig 5b
BD Biosciences GGA3 antibody (BD Transduction Laboratories, 610502) was used in western blot on human samples at 1:1000 (fig 5b). elife (2014) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human
BD Biosciences GGA3 antibody (BD Bioscience, 610386) was used in immunocytochemistry on human samples . Mol Brain (2014) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; human
BD Biosciences GGA3 antibody (BD Transduction, 610386) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human
BD Biosciences GGA3 antibody (BD Biosciences, 610502) was used in western blot on human samples . Mol Biol Cell (2013) ncbi
mouse monoclonal (88/Adaptin)
  • flow cytometry; human
In order to show that BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5, BD Biosciences GGA3 antibody (BD, 610385) was used in flow cytometry on human samples . J Biol Chem (2012) ncbi
mouse monoclonal (74/Adaptin)
  • flow cytometry; human
In order to show that BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5, BD Biosciences GGA3 antibody (BD, 610381) was used in flow cytometry on human samples . J Biol Chem (2012) ncbi
mouse monoclonal (88/Adaptin)
  • other; human; loading ...; tbl 5.1
In order to describe organelle-co-localized cell arrays, BD Biosciences GGA3 antibody (BD Biosciences, 610385) was used in other on human samples (tbl 5.1). Methods Mol Biol (2011) ncbi
Articles Reviewed
  1. Zavodszky E, Hegde R. Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors. elife. 2019;8: pubmed publisher
  2. Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, et al. A SEPT1-based scaffold is required for Golgi integrity and function. J Cell Sci. 2019;132: pubmed publisher
  3. Bagh M, Peng S, Chandra G, Zhang Z, Singh S, Pattabiraman N, et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017;8:14612 pubmed publisher
  4. Delaney J, Patel C, Willis K, Haghighiabyaneh M, Axelrod J, Tancioni I, et al. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017;8:14423 pubmed publisher
  5. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  6. Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P. AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. Sci Rep. 2016;6:29950 pubmed publisher
  7. Elkin S, Oswald N, Reed D, Mettlen M, Macmillan J, Schmid S. Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis. Traffic. 2016;17:1139-49 pubmed publisher
  8. Nkwe D, Pelchen Matthews A, Burden J, Collinson L, Marsh M. The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages. BMC Biol. 2016;14:50 pubmed publisher
  9. Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed publisher
  10. Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  11. O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed publisher
  12. Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  13. Tao W, Moore R, Meng Y, Smith E, Xu X. Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol. J Lipid Res. 2016;57:809-17 pubmed publisher
  14. Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
  15. Schachtner H, Weimershaus M, Stache V, Plewa N, Legler D, Höpken U, et al. Loss of Gadkin Affects Dendritic Cell Migration In Vitro. PLoS ONE. 2015;10:e0143883 pubmed publisher
  16. Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed publisher
  17. Lundgren J, Ahmed S, Schedin Weiss S, Gouras G, Winblad B, Tjernberg L, et al. ADAM10 and BACE1 are localized to synaptic vesicles. J Neurochem. 2015;135:606-15 pubmed publisher
  18. Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
  19. Fink A, Blaum F, Babic Cac M, Ebert S, Lemmermann N, Reddehase M. An endocytic YXXΦ (YRRF) cargo sorting motif in the cytoplasmic tail of murine cytomegalovirus AP2 'adapter adapter' protein m04/gp34 antagonizes virus evasion of natural killer cells. Med Microbiol Immunol. 2015;204:383-94 pubmed publisher
  20. Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
  21. Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed publisher
  22. Umasankar P, Ma L, Thieman J, Jha A, Doray B, Watkins S, et al. A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. elife. 2014;3: pubmed publisher
  23. Tam J, Seah C, Pasternak S. The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid. Mol Brain. 2014;7:54 pubmed publisher
  24. Stahlschmidt W, Robertson M, Robinson P, McCluskey A, Haucke V. Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors. J Biol Chem. 2014;289:4906-18 pubmed publisher
  25. Hirst J, Borner G, Edgar J, Hein M, Mann M, Buchholz F, et al. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell. 2013;24:2558-69 pubmed publisher
  26. Moravec R, Conger K, D Souza R, Allison A, Casanova J. BRAG2/GEP100/IQSec1 interacts with clathrin and regulates ?5?1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5). J Biol Chem. 2012;287:31138-47 pubmed publisher
  27. Hu Y, Janitz M. High-throughput subcellular protein localization using transfected-cell arrays. Subcellular protein localization using cell arrays. Methods Mol Biol. 2011;706:53-72 pubmed publisher