This is a Validated Antibody Database (VAD) review about dog FERMT2, based on 3 published articles (read how Labome selects the articles), using FERMT2 antibody in all methods. It is aimed to help Labome visitors find the most suited FERMT2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FERMT2 synonym: fermitin family homolog 2

Knockout validation
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 8D
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 8A
  • western blot; hamsters; 1:1000; loading ...; fig 1C
In order to establish that Smurf1 controls Kindlin-2 protein levels in cells and hinders integrin activation, Sigma-Aldrich FERMT2 antibody (Sigma-Aldrich, K3269) was used in western blot on human samples at 1:1000 (fig 8D), in western blot knockout validation on mouse samples at 1:1000 (fig 8A) and in western blot on hamsters samples at 1:1000 (fig 1C). J Cell Biol (2017) ncbi
OriGene
mouse monoclonal (OTI14A11)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to assess the prognostic value of an immunohistochemistry-based three-protein signature model in patients with esophageal squamous cell carcinoma, OriGene FERMT2 antibody (Origene, TA500505) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Oncotarget (2015) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 8D
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 8A
  • western blot; hamsters; 1:1000; loading ...; fig 1C
In order to establish that Smurf1 controls Kindlin-2 protein levels in cells and hinders integrin activation, Sigma-Aldrich FERMT2 antibody (Sigma-Aldrich, K3269) was used in western blot on human samples at 1:1000 (fig 8D), in western blot knockout validation on mouse samples at 1:1000 (fig 8A) and in western blot on hamsters samples at 1:1000 (fig 1C). J Cell Biol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
In order to study sorting nexin (SNX) family members interactions with beta integrins, Sigma-Aldrich FERMT2 antibody (Sigma, K3269) was used in western blot on mouse samples (fig 2). J Mol Biol (2014) ncbi
Articles Reviewed
  1. Wei X, Wang X, Zhan J, Chen Y, Fang W, Zhang L, et al. Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation. J Cell Biol. 2017;216:1455-1471 pubmed publisher
  2. Cao H, Zhang S, SHEN J, Wu Z, Wu J, Wang S, et al. A three-protein signature and clinical outcome in esophageal squamous cell carcinoma. Oncotarget. 2015;6:5435-48 pubmed
  3. Tseng H, Thorausch N, Ziegler T, Meves A, Fassler R, Böttcher R. Sorting nexin 31 binds multiple ? integrin cytoplasmic domains and regulates ?1 integrin surface levels and stability. J Mol Biol. 2014;426:3180-3194 pubmed publisher