This is a Validated Antibody Database (VAD) review about dog FANCD2, based on 18 published articles (read how Labome selects the articles), using FANCD2 antibody in all methods. It is aimed to help Labome visitors find the most suited FANCD2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
FANCD2 synonym: Fanconi anemia group D2 protein

Novus Biologicals
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7c
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples at 1:1000 (fig 7c). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 4d
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples at 1:2000 (fig 4d). Cell Rep (2018) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 4d
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in immunohistochemistry on human samples (fig 4d). Mol Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4f
In order to explore the role of Fancd2 in normal development and tumorigenesis, Novus Biologicals FANCD2 antibody (novusbio, NB100-182) was used in western blot on mouse samples (fig 4f). Sci Rep (2017) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 6a
  • immunohistochemistry; human; fig 2a
In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in chromatin immunoprecipitation on human samples (fig 6a) and in immunohistochemistry on human samples (fig 2a). MBio (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 2A
  • western blot; human; loading ...; fig 2C
In order to investigate the role of the PTEN phosphatase in DNA interstrand crosslink repair, Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples (fig 2A) and in western blot on human samples (fig 2C). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 5d
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in immunohistochemistry on human samples (fig 5d). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; tbl 1
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (tbl 1). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples (fig 1). Nat Struct Mol Biol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4c
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in immunocytochemistry on human samples (fig 4c). Cell Rep (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 2
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples at 1:200 (fig 2). Cancer Res (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
In order to show that FANCD2 is needed for genome stability maintenance in response to high-linear energy transfer radiation, Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Cell Cycle (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 5
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples (fig 5). DNA Repair (Amst) (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples (fig 5). DNA Repair (Amst) (2015) ncbi
rabbit polyclonal
  • western blot; human
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in western blot on human samples . Cell Rep (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
In order to study the role of an amino terminal FANCD2 nuclear localization signal in the coordinated nuclear localization of both FANCD2 and FANCI, Novus Biologicals FANCD2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 2b
Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in western blot on human samples (fig 2b). Nucleic Acids Res (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; human
In order to study a novel Fanconi anemia subtype in which SLX4 is mutated, Novus Biologicals FANCD2 antibody (Novus, NB100-182) was used in immunocytochemistry on human samples . Nat Genet (2011) ncbi
Articles Reviewed
  1. Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, et al. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nat Commun. 2018;9:3915 pubmed publisher
  2. Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  3. Kim J, Sturgill D, Sebastian R, Khurana S, Tran A, Edwards G, et al. Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. Mol Cell. 2018;69:36-47.e7 pubmed publisher
  4. Zhang T, Du W, Wilson A, Namekawa S, Andreassen P, Meetei A, et al. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep. 2017;7:45626 pubmed publisher
  5. Spriggs C, Laimins L. FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication. MBio. 2017;8: pubmed publisher
  6. Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher
  7. Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed publisher
  8. Fu C, Begum K, Jordan P, He Y, Overbeek P. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS ONE. 2016;11:e0159800 pubmed publisher
  9. Michl J, Zimmer J, Buffa F, McDermott U, Tarsounas M. FANCD2 limits replication stress and genome instability in cells lacking BRCA2. Nat Struct Mol Biol. 2016;23:755-757 pubmed publisher
  10. Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
  11. Stoepker C, Ameziane N, van der Lelij P, Kooi I, Oostra A, Rooimans M, et al. Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer. Cancer Res. 2015;75:3543-53 pubmed publisher
  12. Zhu J, Su F, Mukherjee S, Mori E, Hu B, Asaithamby A. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle. 2015;14:1809-22 pubmed publisher
  13. Stoepker C, Faramarz A, Rooimans M, van Mil S, Balk J, Velleuer E, et al. DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity. DNA Repair (Amst). 2015;26:54-64 pubmed publisher
  14. Bursomanno S, Beli P, Khan A, Minocherhomji S, Wagner S, Bekker Jensen S, et al. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair (Amst). 2015;25:84-96 pubmed publisher
  15. Huang Y, Leung J, Lowery M, Matsushita N, Wang Y, Shen X, et al. Modularized functions of the Fanconi anemia core complex. Cell Rep. 2014;7:1849-57 pubmed publisher
  16. Boisvert R, Rego M, Azzinaro P, Mauro M, Howlett N. Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. PLoS ONE. 2013;8:e81387 pubmed publisher
  17. Tomida J, Itaya A, Shigechi T, Unno J, Uchida E, Ikura M, et al. A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res. 2013;41:6930-41 pubmed publisher
  18. Stoepker C, Hain K, Schuster B, Hilhorst Hofstee Y, Rooimans M, Steltenpool J, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43:138-41 pubmed publisher