This is a Validated Antibody Database (VAD) review about dog DNM1L, based on 38 published articles (read how Labome selects the articles), using DNM1L antibody in all methods. It is aimed to help Labome visitors find the most suited DNM1L antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNM1L synonym: dynamin-1-like protein

Knockout validation
BD Biosciences
mouse monoclonal (8/DLP1)
  • western blot knockout validation; mouse; fig 2
  • immunohistochemistry - paraffin section; mouse; fig 3
BD Biosciences DNM1L antibody (BD Transduction, 611112) was used in western blot knockout validation on mouse samples (fig 2) and in immunohistochemistry - paraffin section on mouse samples (fig 3). Circ Res (2015) ncbi
BD Biosciences
mouse monoclonal (8/DLP1)
  • western blot; mouse; loading ...; fig 4e
BD Biosciences DNM1L antibody (BD PharMingen, 611113) was used in western blot on mouse samples (fig 4e). Cell Rep (2018) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; 1:1000; fig 1
BD Biosciences DNM1L antibody (BD bioscience, 61113) was used in western blot on mouse samples at 1:1000 (fig 1). Biochem Biophys Res Commun (2018) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat; 1:1000; loading ...; fig 1b
BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in western blot on rat samples at 1:1000 (fig 1b). Cardiovasc Toxicol (2018) ncbi
mouse monoclonal (8/DLP1)
  • western blot; fruit fly; loading ...; fig 4h
BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in western blot on fruit fly samples (fig 4h). Curr Biol (2018) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; fig 2c
BD Biosciences DNM1L antibody (BD Biosciences, 611113) was used in western blot on human samples (fig 2c). Hum Mol Genet (2018) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat; 1:1000; loading ...; fig 4a
BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in western blot on rat samples at 1:1000 (fig 4a). PLoS ONE (2017) ncbi
mouse monoclonal (8/DLP1)
  • immunohistochemistry; mouse; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 2e
In order to research the role of mTOR in mitochondrial dynamics and cell survival, BD Biosciences DNM1L antibody (BD Biosciences, 611113) was used in immunohistochemistry on mouse samples (fig 2c) and in western blot on mouse samples (fig 2e). Mol Cell (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; 1:1000; loading ...; fig 5d
In order to study the role of succinyl-CoA synthase ADP-forming beta subunit in mtDNA stability and mitochondrial dynamics, BD Biosciences DNM1L antibody (BD, 611112) was used in western blot on mouse samples at 1:1000 (fig 5d). Sci Rep (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; loading ...; fig 1a
  • western blot; mouse; loading ...; fig 4a
In order to research the protective effect of Mfn2 on dopaminergic neurons, BD Biosciences DNM1L antibody (BD, 611112) was used in western blot on human samples (fig 1a) and in western blot on mouse samples (fig 4a). Biochim Biophys Acta Mol Basis Dis (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; fig e8a
In order to show the role of Pex3 and Pex14 in generating human peroxisomes, BD Biosciences DNM1L antibody (BD Transduction Laboratories, 611113) was used in western blot on human samples (fig e8a). Nature (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat; 1:1000; loading ...; fig 7b
In order to evaluate the mitochondrial dynamics of the cerebral vasculature of 14-week-old Zucker diabetic fatty obese rats with early type 2 diabetes, BD Biosciences DNM1L antibody (BD Transduction Labs, 611112) was used in western blot on rat samples at 1:1000 (fig 7b). J Vasc Res (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; 1:1000; loading ...
In order to characterize muscle biopsy specimens derived from patients with spinal and bulbar muscular atrophy, BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in western blot on human samples at 1:1000. Hum Mol Genet (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; loading ...; fig 4h
BD Biosciences DNM1L antibody (BD Biosciences, 611113) was used in western blot on human samples (fig 4h). Oncotarget (2017) ncbi
mouse monoclonal (8/DLP1)
  • western blot; African green monkey; loading ...; fig 3b
In order to show that syntaxin-17 is required for the delivery of stress-induced PINK1/parkin-dependent mitochondrial-derived vesicles to the late endosome/lysosome, BD Biosciences DNM1L antibody (BD, 611113) was used in western blot on African green monkey samples (fig 3b). J Cell Biol (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; loading ...; fig 2c
BD Biosciences DNM1L antibody (BD Bioscience, 611113) was used in western blot on human samples (fig 2c). EMBO Mol Med (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; 1:2000; loading ...; fig s2b
In order to test if heme oxygenase-1 mediates cardiac protection by altering mitochondrial quality control, BD Biosciences DNM1L antibody (BD, 611112) was used in western blot on mouse samples at 1:2000 (fig s2b). JCI Insight (2016) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 4
BD Biosciences DNM1L antibody (BD Bioscience, 611112) was used in immunocytochemistry on human samples (fig 4) and in western blot on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat; 1:1000; fig 6
In order to study cerebral vasculature mitochondrial function in insulin-resistant Zucker obese rats, BD Biosciences DNM1L antibody (BD Transduction, 611112) was used in western blot on rat samples at 1:1000 (fig 6). Am J Physiol Heart Circ Physiol (2016) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; mouse; loading ...; fig 4a
  • western blot; mouse; loading ...; fig s5e
In order to study the function of AMP-activated protein kinase in stress-induced mitochondrial fission, BD Biosciences DNM1L antibody (BD, 611113) was used in immunocytochemistry on mouse samples (fig 4a) and in western blot on mouse samples (fig s5e). Science (2016) ncbi
mouse monoclonal (8/DLP1)
  • immunoprecipitation; rat
  • immunocytochemistry; rat; 1:500; fig 2
  • western blot; rat; 1:1000
In order to elucidate how inhibition of vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation occurs by glucagon-like peptide 1, BD Biosciences DNM1L antibody (BD Transduction, 611112) was used in immunoprecipitation on rat samples , in immunocytochemistry on rat samples at 1:500 (fig 2) and in western blot on rat samples at 1:1000. Biochem Pharmacol (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; fig s2
In order to analyze delay of neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by loss of OMA1, BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in western blot on mouse samples (fig s2). J Cell Biol (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; fig 4
BD Biosciences DNM1L antibody (BD Transduction Laboratories, 611112) was used in western blot on mouse samples (fig 4). Mol Psychiatry (2016) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; fig 7
In order to report how the depletion of distinct plectin isoforms differentially affects mitochondrial network organization and function, BD Biosciences DNM1L antibody (BD Pharmingen, 611112) was used in western blot on mouse samples (fig 7). Hum Mol Genet (2015) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse
In order to study the effect of diaphragm contractile inactivity on mitochondrial function, BD Biosciences DNM1L antibody (BD, 611112) was used in western blot on mouse samples . J Appl Physiol (1985) (2015) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human
In order to discuss the role of CD47 modulation in treatment of chronic lymphocytic leukemia, BD Biosciences DNM1L antibody (BD Biosciences, 8/DLP1) was used in western blot on human samples . PLoS Med (2015) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; mouse; 1:100
In order to show that obesity before conception imparts a reversible legacy of mitochondrial loss in offspring that is caused by ER stress, BD Biosciences DNM1L antibody (BD Biosciences, 611112) was used in immunocytochemistry on mouse samples at 1:100. Development (2015) ncbi
mouse monoclonal (8/DLP1)
  • western blot knockout validation; mouse; fig 2
  • immunohistochemistry - paraffin section; mouse; fig 3
BD Biosciences DNM1L antibody (BD Transduction, 611112) was used in western blot knockout validation on mouse samples (fig 2) and in immunohistochemistry - paraffin section on mouse samples (fig 3). Circ Res (2015) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human
In order to determine if mitochondrial fusion protects metabolically challenged mitochondria, BD Biosciences DNM1L antibody (BD, 611113) was used in western blot on human samples . J Cell Sci (2014) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat; 1:1000; fig 3
In order to test if mitochondrial function in the cerebral vasculature is maintained after transient middle cerebral artery occlusion in rats, BD Biosciences DNM1L antibody (BD Transduction, 611112) was used in western blot on rat samples at 1:1000 (fig 3). Am J Physiol Heart Circ Physiol (2014) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; rat
  • immunohistochemistry; rat
  • western blot; rat; 1:400
In order to investigate the role of mitochondria in manganese-induced Parkinsonism, BD Biosciences DNM1L antibody (BD Pharmingen, 611113) was used in immunocytochemistry on rat samples , in immunohistochemistry on rat samples and in western blot on rat samples at 1:400. PLoS ONE (2014) ncbi
mouse monoclonal (8/DLP1)
  • western blot; human; fig 1a
In order to analyze the governing of autophagosome biogenesis during mitophagy via mitochondrial Rab GAPs, BD Biosciences DNM1L antibody (BD, 8/DLP1) was used in western blot on human samples (fig 1a). elife (2014) ncbi
mouse monoclonal (8/DLP1)
  • western blot; mouse; fig 2
BD Biosciences DNM1L antibody (BD transduction laboratories, 611112) was used in western blot on mouse samples (fig 2). Autophagy (2014) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; human; fig 9
In order to demonstrate that wildtype alpha-synuclein localizes mitochondria-associated endoplasmic reticulum membranes and that mutated alpha-synuclein behaves differently, BD Biosciences DNM1L antibody (BD, 611113) was used in immunocytochemistry on human samples (fig 9). J Neurosci (2014) ncbi
mouse monoclonal (8/DLP1)
  • immunoprecipitation; human
In order to unravel the functional relation between mitochondria-shaping proteins and the small GTPase Rab11a, BD Biosciences DNM1L antibody (BD Biosciences, 8/DLP1) was used in immunoprecipitation on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; mouse; 1:200
  • western blot; mouse; 1:1000
BD Biosciences DNM1L antibody (BD Biosciences, 611113) was used in immunocytochemistry on mouse samples at 1:200 and in western blot on mouse samples at 1:1000. Br J Pharmacol (2014) ncbi
mouse monoclonal (8/DLP1)
  • immunohistochemistry; rat
  • western blot; rat
BD Biosciences DNM1L antibody (BD Bioscience, 8/DLP1) was used in immunohistochemistry on rat samples and in western blot on rat samples . Antioxid Redox Signal (2013) ncbi
mouse monoclonal (8/DLP1)
  • western blot; rat
  • western blot; human
BD Biosciences DNM1L antibody (BD Biosciences, 611113) was used in western blot on rat samples and in western blot on human samples . Cell Death Dis (2013) ncbi
mouse monoclonal (8/DLP1)
  • immunocytochemistry; human
  • western blot; human
BD Biosciences DNM1L antibody (BD Transduction Laboratories, 611112) was used in immunocytochemistry on human samples and in western blot on human samples . Biosci Rep (2013) ncbi
Articles Reviewed
  1. Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher
  2. Zhao Y, Sun X, Qi X. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease. Biochem Biophys Res Commun. 2018;507:319-323 pubmed publisher
  3. Yin W, Li R, Feng X, James Kang Y. The Involvement of Cytochrome c Oxidase in Mitochondrial Fusion in Primary Cultures of Neonatal Rat Cardiomyocytes. Cardiovasc Toxicol. 2018;18:365-373 pubmed publisher
  4. Anding A, Wang C, Chang T, Sliter D, Powers C, Hofmann K, et al. Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance. Curr Biol. 2018;28:287-295.e6 pubmed publisher
  5. Straub I, Janer A, Weraarpachai W, Zinman L, Robertson J, Rogaeva E, et al. Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS. Hum Mol Genet. 2018;27:178-189 pubmed publisher
  6. Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur J, Macmillan Crow L. Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLoS ONE. 2017;12:e0185542 pubmed publisher
  7. Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, et al. mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Mol Cell. 2017;67:922-935.e5 pubmed publisher
  8. Zhao Y, Tian J, Sui S, Yuan X, Chen H, Qu C, et al. Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Sci Rep. 2017;7:7169 pubmed publisher
  9. Zhao F, Wang W, Wang C, Siedlak S, Fujioka H, Tang B, et al. Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1359-1370 pubmed publisher
  10. Sugiura A, Mattie S, Prudent J, McBride H. Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes. Nature. 2017;542:251-254 pubmed publisher
  11. Merdzo I, Rutkai I, Sure V, McNulty C, Katakam P, Busija D. Impaired Mitochondrial Respiration in Large Cerebral Arteries of Rats with Type 2 Diabetes. J Vasc Res. 2017;54:1-12 pubmed publisher
  12. Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed publisher
  13. Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  14. McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher
  15. Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 2016;8:1019-38 pubmed publisher
  16. Hull T, Boddu R, Guo L, Tisher C, Traylor A, Patel B, et al. Heme oxygenase-1 regulates mitochondrial quality control in the heart. JCI Insight. 2016;1:e85817 pubmed
  17. Siu G, Zhou F, Yu M, Zhang L, Wang T, Liang Y, et al. Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation. Sci Rep. 2016;6:23464 pubmed publisher
  18. Merdzo I, Rutkai I, Tokés T, Sure V, Katakam P, Busija D. The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats. Am J Physiol Heart Circ Physiol. 2016;310:H830-8 pubmed publisher
  19. Toyama E, Herzig S, Courchet J, Lewis T, Losón O, Hellberg K, et al. Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress. Science. 2016;351:275-281 pubmed publisher
  20. Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
  21. Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
  22. Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
  23. Winter L, Kuznetsov A, Grimm M, Zeöld A, Fischer I, Wiche G. Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle. Hum Mol Genet. 2015;24:4530-44 pubmed publisher
  24. Picard M, Azuelos I, Jung B, Giordano C, Matecki S, Hussain S, et al. Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm. J Appl Physiol (1985). 2015;118:1161-71 pubmed publisher
  25. Martínez Torres A, Quiney C, Attout T, Boullet H, Herbi L, Vela L, et al. CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans. PLoS Med. 2015;12:e1001796 pubmed publisher
  26. Wu L, Russell D, Wong S, Chen M, Tsai T, St John J, et al. Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors. Development. 2015;142:681-91 pubmed publisher
  27. Ikeda Y, Shirakabe A, Maejima Y, Zhai P, Sciarretta S, Toli J, et al. Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress. Circ Res. 2015;116:264-78 pubmed publisher
  28. Lee J, Kapur M, Li M, Choi M, Choi S, Kim H, et al. MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. J Cell Sci. 2014;127:4954-63 pubmed publisher
  29. Rutkai I, Katakam P, Dutta S, Busija D. Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies. Am J Physiol Heart Circ Physiol. 2014;307:H958-66 pubmed publisher
  30. Alaimo A, Gorojod R, Beauquis J, Muñoz M, Saravia F, Kotler M. Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis. PLoS ONE. 2014;9:e91848 pubmed publisher
  31. Yamano K, Fogel A, Wang C, van der Bliek A, Youle R. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. elife. 2014;3:e01612 pubmed publisher
  32. Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed publisher
  33. Guardia Laguarta C, Area Gomez E, Rüb C, Liu Y, Magrane J, Becker D, et al. ?-Synuclein is localized to mitochondria-associated ER membranes. J Neurosci. 2014;34:249-59 pubmed publisher
  34. Landry M, Champagne C, Boulanger M, Jetté A, Fuchs M, Dziengelewski C, et al. A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases. J Biol Chem. 2014;289:2230-49 pubmed publisher
  35. Clerc P, Ge S, Hwang H, Waddell J, Roelofs B, Karbowski M, et al. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes. Br J Pharmacol. 2014;171:1988-99 pubmed publisher
  36. Haun F, Nakamura T, Shiu A, Cho D, Tsunemi T, Holland E, et al. S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease. Antioxid Redox Signal. 2013;19:1173-84 pubmed publisher
  37. Xu S, Pi H, Chen Y, Zhang N, Guo P, Lu Y, et al. Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity. Cell Death Dis. 2013;4:e540 pubmed publisher
  38. Van Beersel G, Tihon E, Demine S, Hamer I, Jadot M, Arnould T. Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts. Biosci Rep. 2013;33:e00023 pubmed publisher