This is a Validated Antibody Database (VAD) review about dog CLDN7, based on 34 published articles (read how Labome selects the articles), using CLDN7 antibody in all methods. It is aimed to help Labome visitors find the most suited CLDN7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CLDN7 synonym: claudin-7

Invitrogen
rabbit polyclonal
  • immunocytochemistry; dog; fig 2
  • western blot; dog; fig 2
In order to study the role of claudin-4 in tight junctions in MDCK cells, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunocytochemistry on dog samples (fig 2) and in western blot on dog samples (fig 2). PLoS ONE (2017) ncbi
rabbit polyclonal
  • western blot; dog; 1:250; loading ...; fig 2d
In order to investigate that role of zonula occludens-2 in Rho protein activation and epithelial development, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in western blot on dog samples at 1:250 (fig 2d). Biochim Biophys Acta Mol Cell Res (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6c
In order to test if HAI-2, matriptase, EpCAM, and claudin-7 are functionally linked in the intestine, Invitrogen CLDN7 antibody (Life Technologies, 34-9100) was used in western blot on human samples (fig 6c). J Clin Invest (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1e
  • immunocytochemistry; human; 1:200; loading ...; fig 2h
  • western blot; human; 1:1000; loading ...; fig s2a
In order to show that the absence of EpCAM in enterocytes results in an aberrant apical domain, Invitrogen CLDN7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1e), in immunocytochemistry on human samples at 1:200 (fig 2h) and in western blot on human samples at 1:1000 (fig s2a). Nat Commun (2017) ncbi
rabbit polyclonal
  • flow cytometry; human; 1:100; loading ...; fig 3a
In order to ascertain how claudin-6 is associated with MMP-2 activation and cell invasiveness, Invitrogen CLDN7 antibody (Invitrogen, 349100) was used in flow cytometry on human samples at 1:100 (fig 3a). Exp Cell Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6e
  • western blot; mouse; 1:1000; loading ...; fig 6a
  • western blot; human; 1:1000; loading ...; fig 2a
In order to examine the role of Salmonella AvrA during infection, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6e), in western blot on mouse samples at 1:1000 (fig 6a) and in western blot on human samples at 1:1000 (fig 2a). J Biol Chem (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3
In order to assess claudin-5 expression in ependymoma, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3). Pathol Oncol Res (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
In order to assess the transiently formed junctional nexuses during post-natal mammary gland development by E-cadherins, connexins, beta-catenin, and claudin-7, Invitrogen CLDN7 antibody (Life Technologies, 34-9100) was used in western blot on mouse samples at 1:1000 (fig 5). Dev Biol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to elucidate regulation of E-cadherin and CD24 by determination of cell fate transition and impeding tumor initiation and progression in breast cancer via HOXA5, Invitrogen CLDN7 antibody (Thermo Fisher Scientific, 34-9100) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 1
In order to utilize a microwave antigen retrieval method by using two heating steps for enhanced immunostaining on tissue sections that are aldehyde-fixed and paraffin-embedded, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry - paraffin section on mouse samples (fig 1). Histochem Cell Biol (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 4
  • western blot; human; fig 1c
In order to elucidate the contribution of SPRY2 to colon cancer, Invitrogen CLDN7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry on human samples (fig 4) and in western blot on human samples (fig 1c). Oncogene (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; rat
In order to investigate the effect of NF-kappaB inhibitors on lung epithelial tight junctions in the absence of inflammation, Invitrogen CLDN7 antibody (Life Technologies, #34-C9100) was used in immunohistochemistry on rat samples . Tissue Barriers (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; dog
  • western blot; dog
In order to characterize TALEN-mediated claudin-2 knockout in MDCK cells, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunocytochemistry on dog samples and in western blot on dog samples . PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; dog
  • western blot; dog
In order to characterize the TALEN-mediated ZO-1 knockout in MDCK cells, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunocytochemistry on dog samples and in western blot on dog samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study the involvement of autocrine CSF1R signaling in claudin-low breast tumor cells, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in western blot on human samples . Oncogene (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse
  • western blot; mouse
In order to characterize tight junctions in the digestive tract of cystic fibrosis mice, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry - frozen section on mouse samples and in western blot on mouse samples . Cell Tissue Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1.25 ug/ml; fig 4
  • western blot; mouse
  • immunohistochemistry - paraffin section; human
In order to study the effects of intestinal barrier proteins in necrotizing enterocolitis and test if Bifidobacterium infantis modulates tight junction proteins, Invitrogen CLDN7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry - frozen section on mouse samples at 1.25 ug/ml (fig 4), in western blot on mouse samples and in immunohistochemistry - paraffin section on human samples . Am J Pathol (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2
  • immunoprecipitation; mouse; fig 2
  • western blot; mouse; 1:5000; fig 2
In order to report that mice lacking EpCAM have intestinal barrier defects and die shortly after birth as a result of intestinal erosion, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2), in immunoprecipitation on mouse samples (fig 2) and in western blot on mouse samples at 1:5000 (fig 2). Dev Biol (2012) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; human; 1:200
  • western blot; human; 1:1000; fig 2
In order to assess the role of tight junctions and gap proteins in cervical remodeling, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used in immunohistochemistry - frozen section on human samples at 1:200 and in western blot on human samples at 1:1000 (fig 2). J Transl Med (2012) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
In order to report that commensal colonization induces intestinal barrier function maturation by promoting claudin 3 expression, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in western blot on mouse samples (fig 3). Am J Pathol (2012) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
In order to assess the use of claudins and E-cadherin as markers for breast cancer prognosis, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). Cancer Sci (2011) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 4
  • western blot; human; fig 3
In order to investigate the role of claudin-7 during colorectal carcinogenesis, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry on human samples (fig 4) and in western blot on human samples (fig 3). BMC Cancer (2011) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to perform a proteomic study of Snail1-regulated events during epithelial-to-mesenchymal transition, Invitrogen CLDN7 antibody (Invitrogen, 34-9100) was used in western blot on human samples (fig 1). PLoS ONE (2010) ncbi
rabbit polyclonal
In order to study the effects of cingulin overexpression, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Mol Membr Biol (2008) ncbi
rabbit polyclonal
In order to ask if urothelial differentiation failure contributes to the aetiopathology of interstitial cystitis, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . BJU Int (2007) ncbi
rabbit polyclonal
In order to examine claudin expression in in endometrioid (type I) and seropapillary (type II) endometrial adenocarcinoma, Invitrogen CLDN7 antibody (Zymed, 349100) was used . Gynecol Oncol (2006) ncbi
rabbit polyclonal
In order to determine the distribution of claudins-7 and -8 in rabbit Henle's loops and collecting ducts, Invitrogen CLDN7 antibody (Zymed, 349100) was used . Nephrol Dial Transplant (2006) ncbi
rabbit polyclonal
In order to investigate the function of cingulin in tight junctions, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Mol Biol Cell (2006) ncbi
rabbit polyclonal
In order to examine the molecular composition of the tight junction present in human term placenta from normal women and from those with preeclampsia, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Cell Tissue Res (2006) ncbi
rabbit polyclonal
In order to characterize cell lines that mimic the characteristics of the proximal tubule, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Toxicol In Vitro (2006) ncbi
rabbit polyclonal
In order to observe the expression of occludin and syndecan-1 in the early phases of cervical carcinogenesis, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Pathol Oncol Res (2005) ncbi
rabbit polyclonal
In order to examine the expression and function of tight junctions in the epithelium of human palatine tonsils from patients with tonsillar hypertrophy or recurrent tonsillitis, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . J Histochem Cytochem (2004) ncbi
rabbit polyclonal
In order to evaluate the effect of three different fixation methods on pathology samples, Invitrogen CLDN7 antibody (Zymed, 349100) was used . Diagn Mol Pathol (2004) ncbi
rabbit polyclonal
In order to explore the role of claudin-7 in cancer progression, Invitrogen CLDN7 antibody (Zymed, 34-9100) was used . Oncogene (2003) ncbi
Articles Reviewed
  1. Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed publisher
  2. Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher
  3. Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed publisher
  4. Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, et al. Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. Nat Commun. 2017;8:13998 pubmed publisher
  5. Torres Martínez A, Gallardo Vera J, Lara Holguin A, Montano L, Rendón Huerta E. Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells. Exp Cell Res. 2017;350:226-235 pubmed publisher
  6. Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed publisher
  7. Virág J, Haberler C, Baksa G, Piurko V, Hegedûs Z, Reiniger L, et al. Region Specific Differences of Claudin-5 Expression in Pediatric Intracranial Ependymomas: Potential Prognostic Role in Supratentorial Cases. Pathol Oncol Res. 2017;23:245-252 pubmed publisher
  8. Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  9. Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed publisher
  10. Gu L, Cong J, Zhang J, Tian Y, Zhai X. A microwave antigen retrieval method using two heating steps for enhanced immunostaining on aldehyde-fixed paraffin-embedded tissue sections. Histochem Cell Biol. 2016;145:675-80 pubmed publisher
  11. Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed publisher
  12. Ward C, Schlingmann B, Stecenko A, Guidot D, Koval M. NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation. Tissue Barriers. 2015;3:e982424 pubmed publisher
  13. Tokuda S, Furuse M. Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS ONE. 2015;10:e0119869 pubmed publisher
  14. Tokuda S, Higashi T, Furuse M. ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. PLoS ONE. 2014;9:e104994 pubmed publisher
  15. Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, et al. Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGF? in claudin-low breast tumor cells. Oncogene. 2015;34:2721-31 pubmed publisher
  16. De Lisle R. Disrupted tight junctions in the small intestine of cystic fibrosis mice. Cell Tissue Res. 2014;355:131-42 pubmed publisher
  17. Bergmann K, Liu S, Tian R, Kushnir A, Turner J, Li H, et al. Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis. Am J Pathol. 2013;182:1595-606 pubmed publisher
  18. Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, et al. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012;371:136-45 pubmed publisher
  19. Ghule V, Gray C, Galimberti A, Anumba D. Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins. J Transl Med. 2012;10:40 pubmed publisher
  20. Patel R, Myers L, Kurundkar A, Maheshwari A, Nusrat A, Lin P. Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function. Am J Pathol. 2012;180:626-35 pubmed publisher
  21. Szász A, Nemeth Z, Gyorffy B, Micsinai M, Krenacs T, Baranyai Z, et al. Identification of a claudin-4 and E-cadherin score to predict prognosis in breast cancer. Cancer Sci. 2011;102:2248-54 pubmed publisher
  22. Bornholdt J, Friis S, Godiksen S, Poulsen S, Santoni Rugiu E, Bisgaard H, et al. The level of claudin-7 is reduced as an early event in colorectal carcinogenesis. BMC Cancer. 2011;11:65 pubmed publisher
  23. Larriba M, Casado Vela J, Pendás Franco N, Peña R, Garcia de Herreros A, Berciano M, et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS ONE. 2010;5:e10221 pubmed publisher
  24. Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13 pubmed
  25. Southgate J, Varley C, Garthwaite M, Hinley J, Marsh F, Stahlschmidt J, et al. Differentiation potential of urothelium from patients with benign bladder dysfunction. BJU Int. 2007;99:1506-16 pubmed
  26. Sobel G, Nemeth J, Kiss A, Lotz G, Szabo I, Udvarhelyi N, et al. Claudin 1 differentiates endometrioid and serous papillary endometrial adenocarcinoma. Gynecol Oncol. 2006;103:591-8 pubmed
  27. Gonzalez Mariscal L, Namorado M, Martin D, Sierra G, Reyes J. The tight junction proteins claudin-7 and -8 display a different subcellular localization at Henle's loops and collecting ducts of rabbit kidney. Nephrol Dial Transplant. 2006;21:2391-8 pubmed
  28. Guillemot L, Citi S. Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell. 2006;17:3569-77 pubmed
  29. Liévano S, Alarcón L, Chavez Munguia B, Gonzalez Mariscal L. Endothelia of term human placentae display diminished expression of tight junction proteins during preeclampsia. Cell Tissue Res. 2006;324:433-48 pubmed
  30. Prozialeck W, Edwards J, Lamar P, Smith C. Epithelial barrier characteristics and expression of cell adhesion molecules in proximal tubule-derived cell lines commonly used for in vitro toxicity studies. Toxicol In Vitro. 2006;20:942-53 pubmed
  31. Sobel G, Szabo I, Páska C, Kiss A, Kovalszky I, Kadar A, et al. Changes of cell adhesion and extracellular matrix (ECM) components in cervical intraepithelial neoplasia. Pathol Oncol Res. 2005;11:26-31 pubmed
  32. Go M, Kojima T, Takano K, Murata M, Ichimiya S, Tsubota H, et al. Expression and function of tight junctions in the crypt epithelium of human palatine tonsils. J Histochem Cytochem. 2004;52:1627-38 pubmed
  33. Páska C, Bögi K, Szilak L, Tokés A, Szabó E, Sziller I, et al. Effect of formalin, acetone, and RNAlater fixatives on tissue preservation and different size amplicons by real-time PCR from paraffin-embedded tissue. Diagn Mol Pathol. 2004;13:234-40 pubmed
  34. Kominsky S, Argani P, Korz D, Evron E, Raman V, Garrett E, et al. Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene. 2003;22:2021-33 pubmed