This is a Validated Antibody Database (VAD) review about dog CFL1, based on 37 published articles (read how Labome selects the articles), using CFL1 antibody in all methods. It is aimed to help Labome visitors find the most suited CFL1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CFL1 synonym: cofilin-1

Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3a
In order to research the role of BAF53b mutations in intellectual disabilities and cognitive disorders, Abcam CFL1 antibody (Abcam, Ab12866) was used in immunohistochemistry on mouse samples at 1:500 (fig 3a). Learn Mem (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
In order to find that frictional force characteristic of flow in the lymphatics stimulates YAP1 to drive cancer cell migration, Abcam CFL1 antibody (Abcam, ab12866) was used in western blot on human samples (fig 4d). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s9
In order to determine regulation of spine structural plasticity and memory and learning by the calcium sensor Copine-6, Abcam CFL1 antibody (Abcam, ab11062) was used in western blot on mouse samples at 1:1000 (fig s9). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:800; fig 4
  • western blot; rat; 1:8000; fig 1
In order to investigate the temporally associated cessation of growth in the developing hippocampus by cofilin activation, Abcam CFL1 antibody (Abcam, Ab12866) was used in immunocytochemistry on rat samples at 1:800 (fig 4) and in western blot on rat samples at 1:8000 (fig 1). Cereb Cortex (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 9a
Abcam CFL1 antibody (Abcam, ab11062) was used in immunocytochemistry on human samples (fig 9a). elife (2015) ncbi
rabbit polyclonal
  • western blot; hamsters; 1:200-1:500; fig 2
Abcam CFL1 antibody (Abcam, ab12866) was used in western blot on hamsters samples at 1:200-1:500 (fig 2). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
In order to study the temporal and spatial relationship between dendritic protein synthesis and actin cytoskeleton reorganization, Abcam CFL1 antibody (Abcam, ab12866) was used in western blot on rat samples at 1:1000. J Neurosci (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human
Abcam CFL1 antibody (Abcam, ab11062) was used in immunocytochemistry on human samples . Histochem Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
Abcam CFL1 antibody (Abcam, ab12866) was used in western blot on rat samples at 1:500. J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000
In order to study 5-HT7R in a mouse model of Rett syndrome, Abcam CFL1 antibody (Abcam, ab1106250) was used in western blot on mouse samples at 1:5000. Neuropsychopharmacology (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:100
In order to study 5-HT7R in a mouse model of Rett syndrome, Abcam CFL1 antibody (Abcam, ab1286650) was used in western blot on mouse samples at 1:100. Neuropsychopharmacology (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:300
Abcam CFL1 antibody (Abcam, ab12866) was used in immunocytochemistry on rat samples at 1:300. PLoS ONE (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:150
  • western blot; rat; 1:200
Abcam CFL1 antibody (Abcam, ab12866) was used in immunocytochemistry on rat samples at 1:150 and in western blot on rat samples at 1:200. Mol Neurobiol (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:10,000
Abcam CFL1 antibody (Abcam, ab11062) was used in western blot on rat samples at 1:10,000. Neuropharmacology (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:300
  • immunocytochemistry; human; 1:1000
  • western blot; human; 1:1000
Abcam CFL1 antibody (Abcam, ab12866) was used in immunohistochemistry - paraffin section on human samples at 1:300, in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:1000. PLoS ONE (2012) ncbi
Cell Signaling Technology
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; loading ...; fig 5e
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:1000 (fig 5e). J Exp Med (2018) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; loading ...; fig 4j
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples at 1:1000 (fig 4j). Nat Commun (2017) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:50; fig 5b
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:50 (fig 5b). J Cell Biol (2017) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology CFL1 antibody (CST, 5175) was used in western blot on mouse samples (fig 5b). PLoS ONE (2017) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; loading ...; fig 3g
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on mouse samples at 1:1000 (fig 3g). J Biol Chem (2017) ncbi
rabbit monoclonal (D3F9)
  • flow cytometry; human; loading ...; fig 4c
In order to suggest that persistent immune activation causes impairment of lymphocytes to respond to chemotactic stimuli, preventing their trafficking from the blood stream to peripheral organs, Cell Signaling Technology CFL1 antibody (Cell Signaling, D3F9) was used in flow cytometry on human samples (fig 4c). J Immunol (2017) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
rabbit monoclonal (D3F9)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 9a
In order to explore the role of CAP2 in the brain, Cell Signaling Technology CFL1 antibody (Cell signaling, D3F9) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8c) and in western blot on mouse samples at 1:1000 (fig 9a). Front Cell Neurosci (2016) ncbi
rabbit monoclonal (D3F9)
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
  • western blot; human; 1:700; loading ...; fig 3c
In order to study the contribution of cofilin in osteoblastic mechanotransduction, Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in immunocytochemistry on human samples at 1:100 (fig 2e) and in western blot on human samples at 1:700 (fig 3c). Mol Med Rep (2016) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; fig 7
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples (fig 7). Cell Death Dis (2016) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2016) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; fig s2
In order to determine how inhibition of human glioblastoma invasion by actin polymerization can occur by an anti-depressant called fluvoxamine, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175) was used in western blot on human samples (fig s2). Sci Rep (2016) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:2000; fig 1
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175P) was used in western blot on mouse samples at 1:2000 (fig 1). J Cell Biol (2016) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; fig 3
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on mouse samples (fig 3). Front Immunol (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; fig 4
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; fig s2
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on human samples (fig s2). J Cell Biol (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; human; fig s4
Cell Signaling Technology CFL1 antibody (Cell signaling, 5175) was used in western blot on human samples (fig s4). PLoS ONE (2015) ncbi
rabbit monoclonal (D3F9)
  • immunoprecipitation; human; fig 6
  • immunocytochemistry; human; fig 6
  • western blot; human; fig 6
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175P) was used in immunoprecipitation on human samples (fig 6), in immunocytochemistry on human samples (fig 6) and in western blot on human samples (fig 6). Oncotarget (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology CFL1 antibody (CST, 5175) was used in western blot on mouse samples (fig 3a). Cell Death Differ (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; rat; 1:1000
In order to study the temporal and spatial relationship between dendritic protein synthesis and actin cytoskeleton reorganization, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, #5175) was used in western blot on rat samples at 1:1000. J Neurosci (2015) ncbi
rabbit monoclonal (D3F9)
  • western blot; mouse; 1:1000
In order to study the role of soluble mutant amyloid precursor protein on cognitive function and synaptic structure, Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, #5175) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
rabbit monoclonal (D3F9)
  • chromatin immunoprecipitation; human
Cell Signaling Technology CFL1 antibody (Cell Signaling Technology, 5175S) was used in chromatin immunoprecipitation on human samples . Mol Cancer Res (2014) ncbi
rabbit monoclonal (D3F9)
  • immunohistochemistry - paraffin section; human; 1:400
  • immunocytochemistry; human; 1:1000; fig 4
  • western blot; human; 1:1000
Cell Signaling Technology CFL1 antibody (Cell Signaling, 5175) was used in immunohistochemistry - paraffin section on human samples at 1:400, in immunocytochemistry on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:1000. PLoS ONE (2012) ncbi
BD Biosciences
mouse monoclonal (32/Cofilin)
  • western blot; human; fig 2
In order to study a novel compound via preclinical validation that targets p70SR kinase in breast cancer, BD Biosciences CFL1 antibody (BD Biosciences, 612145) was used in western blot on human samples (fig 2). Aging (Albany NY) (2016) ncbi
mouse monoclonal (32/Cofilin)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences CFL1 antibody (BD, 32) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Articles Reviewed
  1. Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed publisher
  2. Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
  3. Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher
  4. Vogel Ciernia A, Kramár E, Matheos D, Havekes R, Hemstedt T, Magnan C, et al. Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling. Learn Mem. 2017;24:199-209 pubmed publisher
  5. Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher
  6. Lee H, Diaz M, Price K, Ozuna J, Zhang S, Sevick Muraca E, et al. Fluid shear stress activates YAP1 to promote cancer cell motility. Nat Commun. 2017;8:14122 pubmed publisher
  7. Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed publisher
  8. Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  9. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  10. Kumar A, Paeger L, Kosmas K, Kloppenburg P, Noegel A, Peche V. Neuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2. Front Cell Neurosci. 2016;10:180 pubmed publisher
  11. Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
  12. Gao J, Fu S, Zeng Z, Li F, Niu Q, Jing D, et al. Cyclic stretch promotes osteogenesis-related gene expression in osteoblast-like cells through a cofilin-associated mechanism. Mol Med Rep. 2016;14:218-24 pubmed publisher
  13. Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher
  14. Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher
  15. Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
  16. Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed publisher
  17. Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei F, et al. Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization. Sci Rep. 2016;6:23372 pubmed publisher
  18. Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed publisher
  19. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  20. Lu K, Tounsi A, Shridhar N, Küblbeck G, Klevenz A, Prokosch S, et al. Dickkopf-3 Contributes to the Regulation of Anti-Tumor Immune Responses by Mesenchymal Stem Cells. Front Immunol. 2015;6:645 pubmed publisher
  21. Tojkander S, Gateva G, Husain A, Krishnan R, Lappalainen P. Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly. elife. 2015;4:e06126 pubmed publisher
  22. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  23. Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed publisher
  24. Newell Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed publisher
  25. Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed publisher
  26. Dugina V, Khromova N, Rybko V, Blizniukov O, Shagieva G, Chaponnier C, et al. Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget. 2015;6:14556-71 pubmed
  27. Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
  28. Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
  29. Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
  30. Sun L, Guo C, Wang T, Li X, Li G, Luo Y, et al. LIMK1 is involved in the protective effects of bone morphogenetic protein 6 against amyloid-?-induced neurotoxicity in rat hippocampal neurons. J Alzheimers Dis. 2014;42:543-54 pubmed publisher
  31. Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed publisher
  32. De Filippis B, Nativio P, Fabbri A, Ricceri L, Adriani W, Lacivita E, et al. Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome. Neuropsychopharmacology. 2014;39:2506-18 pubmed publisher
  33. Calabrese B, Saffin J, Halpain S. Activity-dependent dendritic spine shrinkage and growth involve downregulation of cofilin via distinct mechanisms. PLoS ONE. 2014;9:e94787 pubmed publisher
  34. Samuel F, Reddy J, Kaimal R, Segovia V, Mo H, Hynds D. Inhibiting geranylgeranylation increases neurite branching and differentially activates cofilin in cell bodies and growth cones. Mol Neurobiol. 2014;50:49-59 pubmed publisher
  35. Madak Erdogan Z, Ventrella R, Petry L, Katzenellenbogen B. Novel roles for ERK5 and cofilin as critical mediators linking ER?-driven transcription, actin reorganization, and invasiveness in breast cancer. Mol Cancer Res. 2014;12:714-27 pubmed publisher
  36. Regenhardt R, Desland F, Mecca A, Pioquinto D, Afzal A, Mocco J, et al. Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke. Neuropharmacology. 2013;71:154-63 pubmed publisher
  37. Polachini G, Sobral L, Mercante A, Paes Leme A, Xavier F, Henrique T, et al. Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis. PLoS ONE. 2012;7:e50517 pubmed publisher