This is a Validated Antibody Database (VAD) review about dog CDC42, based on 16 published articles (read how Labome selects the articles), using CDC42 antibody in all methods. It is aimed to help Labome visitors find the most suited CDC42 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDC42 synonym: cell division control protein 42 homolog; CDC42 GTP-binding protein; G25K GTP-binding protein; cell division cycle 42 (GTP binding protein, 25kDa)

Knockout validation
BD Biosciences
mouse monoclonal (44/CDC42)
  • western blot knockout validation; mouse; loading ...; fig 3a
BD Biosciences CDC42 antibody (BD Biosciences, 610929) was used in western blot knockout validation on mouse samples (fig 3a). J Biol Chem (2018) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 1i
In order to study the mechanism of internalization of CXCR4 receptor dependent on MIM and small Rab GTPases., Cell Signaling Technology CDC42 antibody (CST, 2462S) was used in western blot on human samples (fig 1i). J Cell Sci (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s3i
Cell Signaling Technology CDC42 antibody (Cell Signaling, 2462) was used in western blot on human samples at 1:1000 (fig s3i). J Cell Biol (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4c
In order to explore how extracellular translationally controlled tumor protein affects colon cancer progression, Cell Signaling Technology CDC42 antibody (Cell Signaling Technology, 2462) was used in immunocytochemistry on human samples (fig 4d) and in western blot on human samples (fig 4c). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
  • western blot; rat; fig 4
Cell Signaling Technology CDC42 antibody (Cell Signaling, 2462) was used in western blot on human samples (fig 2) and in western blot on rat samples (fig 4). J Am Heart Assoc (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology CDC42 antibody (Cell Signaling Tech, 2462) was used in western blot on human samples (fig 1). PLoS Pathog (2015) ncbi
BD Biosciences
mouse monoclonal (44/CDC42)
  • immunoprecipitation; mouse; loading ...; fig 6c
BD Biosciences CDC42 antibody (BD Biosciences, 610928) was used in immunoprecipitation on mouse samples (fig 6c). FASEB J (2019) ncbi
mouse monoclonal (44/CDC42)
  • western blot knockout validation; mouse; loading ...; fig 3a
BD Biosciences CDC42 antibody (BD Biosciences, 610929) was used in western blot knockout validation on mouse samples (fig 3a). J Biol Chem (2018) ncbi
mouse monoclonal (44/CDC42)
  • western blot; rat; loading ...; fig 3c
In order to perform whole exome sequencing to identify recessive causes of steroid-resistant nephrotic syndrome, BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610928) was used in western blot on rat samples (fig 3c). J Clin Invest (2017) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; fig 8
BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610929) was used in western blot on mouse samples (fig 8). Cell Death Dis (2017) ncbi
mouse monoclonal (44/CDC42)
  • western blot; human; fig 1s1
BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610929) was used in western blot on human samples (fig 1s1). elife (2016) ncbi
mouse monoclonal (44/CDC42)
  • immunocytochemistry; human; 1:300; fig s5i
  • western blot; human; 1:300; fig s5f
In order to identify factors that regulate the stability of the RhoA zone, BD Biosciences CDC42 antibody (BD Biosciences, 610928) was used in immunocytochemistry on human samples at 1:300 (fig s5i) and in western blot on human samples at 1:300 (fig s5f). Nat Cell Biol (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; fig 4
BD Biosciences CDC42 antibody (Becton Dickinson, 610928) was used in western blot on mouse samples (fig 4). Mol Biol Cell (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; human; fig s5
BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610929) was used in western blot on human samples (fig s5). Hum Genet (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; zebrafish ; fig 1d
BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610929) was used in western blot on zebrafish samples (fig 1d). Invest Ophthalmol Vis Sci (2015) ncbi
mouse monoclonal (44/CDC42)
  • immunocytochemistry; human; fig s4g
BD Biosciences CDC42 antibody (BD, 610929) was used in immunocytochemistry on human samples (fig s4g). J Cell Biol (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; 1:1000
In order to study the role of cell migration in the mechanism by which overexpression of Cdc42 promotes developing mammary gland hyperbranching, BD Biosciences CDC42 antibody (BD Transduction Laboratories, 610929) was used in western blot on mouse samples at 1:1000. Breast Cancer Res (2013) ncbi
Articles Reviewed
  1. Huang K, Ru B, Zhang Y, Chan W, Chow S, Zhang J, et al. Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation. FASEB J. 2019;33:7588-7602 pubmed publisher
  2. Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
  3. Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
  4. Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed publisher
  5. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  6. Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed publisher
  7. Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  8. Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
  9. Yu D, Makkar G, Strickland D, Blanpied T, Stumpo D, Blackshear P, et al. Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation. J Am Heart Assoc. 2015;4:e002255 pubmed publisher
  10. Priya R, Gomez G, Budnar S, Verma S, Cox H, Hamilton N, et al. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol. 2015;17:1282-93 pubmed publisher
  11. Gramolelli S, Weidner Glunde M, Abere B, Viejo Borbolla A, Bala K, Rückert J, et al. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells. PLoS Pathog. 2015;11:e1005105 pubmed publisher
  12. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher
  13. Hwang D, Kohl S, Fan X, Vivante A, Chan S, Dworschak G, et al. Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. Hum Genet. 2015;134:905-16 pubmed publisher
  14. Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
  15. Artym V, Swatkoski S, Matsumoto K, Campbell C, Petrie R, Dimitriadis E, et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol. 2015;208:331-50 pubmed publisher
  16. Bray K, Gillette M, Young J, Loughran E, Hwang M, Sears J, et al. Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res. 2013;15:R91 pubmed