This is a Validated Antibody Database (VAD) review about dog CASQ2, based on 7 published articles (read how Labome selects the articles), using CASQ2 antibody in all methods. It is aimed to help Labome visitors find the most suited CASQ2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CASQ2 synonym: CAL; calsequestrin-2; calsequestrin, cardiac muscle isoform; cardiac calsequestrin

Abcam
rabbit polyclonal
  • western blot; mouse; 1:800; fig 2
In order to analyze slow twitch skeletal muscles and the role of the JP45-calsequestrin complex on calcium entry, Abcam CASQ2 antibody (Abcam, Ab3516) was used in western blot on mouse samples at 1:800 (fig 2). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to assess the function and characterization of extraocular muscles and obicularis oculi, Abcam CASQ2 antibody (Abcam, 3516) was used in western blot on human samples (fig 1). J Gen Physiol (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to characterize the effect of cyclosporine A treatment in a mouse model of lethal mitochondrial myopathy, Abcam CASQ2 antibody (Abcam, ab3516) was used in western blot on human samples . Hum Mol Genet (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of RyR in regulating calcium levels in extraocular muscles, Abcam CASQ2 antibody (Abcam, ab-3516) was used in western blot on human samples . Biochem J (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to ascertain the relationship between sarcoplasmic reticulum calcium content and calsequestrin isoforms in human skeletal muscle, Abcam CASQ2 antibody (Abcam, Ab3516) was used in western blot on human samples at 1:1000. J Physiol (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50
  • western blot; mouse; 1:2500
Abcam CASQ2 antibody (Abcam, ab3516) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 and in western blot on mouse samples at 1:2500. Biochem Pharmacol (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:4000
Abcam CASQ2 antibody (Abcam, ab3516) was used in western blot on mouse samples at 1:4000. Am J Physiol Heart Circ Physiol (2013) ncbi
Articles Reviewed
  1. Mosca B, Eckhardt J, Bergamelli L, Treves S, Bongianino R, De Negri M, et al. Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles. J Biol Chem. 2016;291:14555-65 pubmed publisher
  2. Sekulic Jablanovic M, Ullrich N, Goldblum D, Palmowski Wolfe A, Zorzato F, Treves S. Functional characterization of orbicularis oculi and extraocular muscles. J Gen Physiol. 2016;147:395-406 pubmed publisher
  3. Gineste C, Hernandez A, Ivarsson N, Cheng A, Naess K, Wibom R, et al. Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy. Hum Mol Genet. 2015;24:6580-7 pubmed publisher
  4. Sekulic Jablanovic M, Palmowski Wolfe A, Zorzato F, Treves S. Characterization of excitation-contraction coupling components in human extraocular muscles. Biochem J. 2015;466:29-36 pubmed publisher
  5. Lamboley C, Murphy R, McKenna M, Lamb G. Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres. J Physiol. 2013;591:6053-68 pubmed publisher
  6. Katz G, Shainberg A, Hochhauser E, Kurtzwald Josefson E, Issac A, El Ani D, et al. The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2). Biochem Pharmacol. 2013;86:1576-83 pubmed publisher
  7. Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher