This is a Validated Antibody Database (VAD) review about dog BRAF, based on 6 published articles (read how Labome selects the articles), using BRAF antibody in all methods. It is aimed to help Labome visitors find the most suited BRAF antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BRAF synonym: serine/threonine-protein kinase B-raf; B-raf protein; v-raf murine sarcoma viral oncogene homolog B1

Cell Signaling Technology
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology BRAF antibody (Cell Signaling, 2696) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; fig 1c
In order to assess the effects of LY3009120, a panRAF and RAF dimer inhibitor, in human models of colorectal cancer, Cell Signaling Technology BRAF antibody (Cell Signaling, 2696) was used in western blot on human samples (fig 1c). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:100; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology BRAF antibody (Cell Signaling, 2696) was used in western blot on human samples at 1:100 (fig st1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 3c
Cell Signaling Technology BRAF antibody (Cell Signaling, 2696) was used in western blot on human samples at 1:500 (fig 3c). Am J Physiol Lung Cell Mol Physiol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3b
Cell Signaling Technology BRAF antibody (Cell Signaling, 2696) was used in western blot on human samples (fig 3b). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology BRAF antibody (Cell Signaling, # 2696) was used in western blot on human samples . Oncotarget (2015) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan X, et al. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer. Oncotarget. 2017;8:9251-9266 pubmed publisher
  3. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  4. Awad K, Elinoff J, Wang S, Gairhe S, Ferreyra G, Cai R, et al. Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2016;310:L187-201 pubmed publisher
  5. Condelli V, Maddalena F, Sisinni L, Lettini G, Matassa D, Piscazzi A, et al. Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma. Oncotarget. 2015;6:22298-309 pubmed
  6. Petti C, Picco G, Martelli M, Trisolini E, Bucci E, Perera T, et al. Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells. Oncotarget. 2015;6:221-33 pubmed