This is a Validated Antibody Database (VAD) review about dog BECN1, based on 15 published articles (read how Labome selects the articles), using BECN1 antibody in all methods. It is aimed to help Labome visitors find the most suited BECN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
BECN1 synonym: Beclin-1; beclin-1; beclin 1, autophagy related

Knockout validation
BD Biosciences
mouse monoclonal (20/Beclin)
  • western blot knockout validation; human; fig 1
BD Biosciences BECN1 antibody (BD Transduction Laboratories, 612112) was used in western blot knockout validation on human samples (fig 1). Autophagy (2015) ncbi
Novus Biologicals
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e
In order to determine the effects of modulating autophagy in a mouse model of metastatic cancer, Novus Biologicals BECN1 antibody (Novus Biologicals, NB110-87318) was used in western blot on mouse samples (fig 3e). J Pharmacol Exp Ther (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 9
Novus Biologicals BECN1 antibody (Novus Biologicals, NB110-87318) was used in western blot on mouse samples (fig 9). Autophagy (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to discuss the role of autophagy in cell death, Novus Biologicals BECN1 antibody (Novus Biologicals, NB110-87318) was used in western blot on human samples . Biochem Pharmacol (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Novus Biologicals BECN1 antibody (Novus Biologics, NB110-87318) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
Abcam
rabbit polyclonal
  • western blot; human
Abcam BECN1 antibody (Abcam, ab183335) was used in western blot on human samples . PLoS ONE (2014) ncbi
BD Biosciences
mouse monoclonal (20/Beclin)
  • western blot; mouse; 1:3000; loading ...; fig 4a
BD Biosciences BECN1 antibody (BD Bioscience, 612112) was used in western blot on mouse samples at 1:3000 (fig 4a). J Lipid Res (2018) ncbi
mouse monoclonal (20/Beclin)
  • western blot; human; loading ...; fig 3a
BD Biosciences BECN1 antibody (BD Transduction lab, 612113) was used in western blot on human samples (fig 3a). Cell Death Dis (2017) ncbi
mouse monoclonal (20/Beclin)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 5
BD Biosciences BECN1 antibody (BD Biosciences, 612112) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (20/Beclin)
  • western blot; human; loading ...; fig s2a
BD Biosciences BECN1 antibody (BD Biosciences, 612113) was used in western blot on human samples (fig s2a). Autophagy (2016) ncbi
mouse monoclonal (20/Beclin)
  • western blot; human; fig 6
BD Biosciences BECN1 antibody (BD Pharmingen, m612112) was used in western blot on human samples (fig 6). Oncotarget (2016) ncbi
mouse monoclonal (20/Beclin)
  • western blot; mouse; 1:500; fig 1
In order to discuss the role of Beclin 1 in neurodegeneration, BD Biosciences BECN1 antibody (BD Biosciences, 612113) was used in western blot on mouse samples at 1:500 (fig 1). Mol Neurodegener (2015) ncbi
mouse monoclonal (20/Beclin)
  • western blot knockout validation; human; fig 1
BD Biosciences BECN1 antibody (BD Transduction Laboratories, 612112) was used in western blot knockout validation on human samples (fig 1). Autophagy (2015) ncbi
mouse monoclonal (20/Beclin)
  • western blot; mouse; 1:2000
In order to study the regulation of autophagosome biogenesis by connexins, BD Biosciences BECN1 antibody (BD Biosciences, 612112) was used in western blot on mouse samples at 1:2000. Nat Cell Biol (2014) ncbi
mouse monoclonal (20/Beclin)
  • immunohistochemistry; rat; 1:500
  • western blot; rat; 1:500
BD Biosciences BECN1 antibody (BD Transduction Laboratories, 612113) was used in immunohistochemistry on rat samples at 1:500 and in western blot on rat samples at 1:500. Exp Neurol (2014) ncbi
mouse monoclonal (20/Beclin)
  • western blot; human
BD Biosciences BECN1 antibody (BD Pharmingen, 612112) was used in western blot on human samples . J Biol Chem (2013) ncbi
Articles Reviewed
  1. Sun H, Krauss R, Chang J, Teng B. PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction. J Lipid Res. 2018;59:207-223 pubmed publisher
  2. Nascimbeni A, Fanin M, Angelini C, Sandri M. Autophagy dysregulation in Danon disease. Cell Death Dis. 2017;8:e2565 pubmed publisher
  3. Barnard R, Regan D, Hansen R, Maycotte P, Thorburn A, Gustafson D. Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease. J Pharmacol Exp Ther. 2016;358:282-93 pubmed publisher
  4. Wang L, Yokoyama K, Lin C, Chen T, Hsiao H, Chiang P, et al. Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice. Sci Rep. 2016;6:26358 pubmed publisher
  5. Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed publisher
  6. Follo C, Barbone D, Richards W, Bueno R, Broaddus V. Autophagy initiation correlates with the autophagic flux in 3D models of mesothelioma and with patient outcome. Autophagy. 2016;12:1180-94 pubmed publisher
  7. Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed publisher
  8. O Brien C, Bonanno L, Zhang H, Wyss Coray T. Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5. Mol Neurodegener. 2015;10:69 pubmed publisher
  9. Mattiolo P, Yuste V, Boix J, Ribas J. Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation. Biochem Pharmacol. 2015;98:573-86 pubmed publisher
  10. He R, Peng J, Yuan P, Xu F, Wei W. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function. Autophagy. 2015;11:740-7 pubmed publisher
  11. Li C, Chen J, Lu B, Shi Z, Wang H, Zhang B, et al. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS ONE. 2014;9:e101526 pubmed publisher
  12. Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed publisher
  13. Carloni S, Albertini M, Galluzzi L, Buonocore G, Proietti F, Balduini W. Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp Neurol. 2014;255:103-12 pubmed publisher
  14. Baldo B, Soylu R, Petersen A. Maintenance of basal levels of autophagy in Huntington's disease mouse models displaying metabolic dysfunction. PLoS ONE. 2013;8:e83050 pubmed publisher
  15. Ramírez Peinado S, León Annicchiarico C, Galindo Moreno J, Iurlaro R, Caro Maldonado A, Prehn J, et al. Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem. 2013;288:30387-98 pubmed publisher