This is a Validated Antibody Database (VAD) review about dog ATP2A2, based on 67 published articles (read how Labome selects the articles), using ATP2A2 antibody in all methods. It is aimed to help Labome visitors find the most suited ATP2A2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ATP2A2 synonym: SERCA2A; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca(2+)-ATPase 2; calcium ATPase; calcium pump 2; calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic reticulum Ca2+-transport ATPase isoform
Invitrogen
mouse monoclonal (2A7-A1) |
| Invitrogen ATP2A2 antibody (ThermoFisher, MA3-919) was used in western blot on mouse samples at 1:1000 (fig 4a). elife (2019) ncbi |
mouse monoclonal (2A7-A1) |
| Invitrogen ATP2A2 antibody (Thermo Fisher Scientific, MA3-919) was used in western blot on mouse samples (fig 1g). Hum Mol Genet (2018) ncbi |
mouse monoclonal (2A7-A1) | Invitrogen ATP2A2 antibody (Fisher Scientific, MA3-919) was used . Nat Commun (2017) ncbi | |
mouse monoclonal (2A7-A1) |
| In order to test if in utero particulate matter exposure alters cardiac structure and function at adulthood, Invitrogen ATP2A2 antibody (Thermo Fisher, MA3-919) was used in western blot on mouse samples (fig 7a). J Am Heart Assoc (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on mouse samples at 1:1000 (fig s2f). Nat Commun (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to report the physiological role of sarcolipin upregulation in muscle myopathy, Invitrogen ATP2A2 antibody (Pierce Antibodies, MA3-919) was used in western blot on mouse samples (fig 2c). PLoS ONE (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to test the ability of the Notch inhibitor DAPT to convert murine fibroblasts into cardiomyocytes, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on mouse samples at 1:1000 (fig 3e). Stem Cell Reports (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to assess the role of redox stress in PH-induced diaphragm weakness, Invitrogen ATP2A2 antibody (Thermo, MA3-919) was used in western blot on rat samples (fig 2e). PLoS ONE (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to evaluate the impacts of high fat diet on the insulin-adrenergic receptor signal network in hearts, Invitrogen ATP2A2 antibody (Thermo, 2A7-A1) was used in western blot on mouse samples at 1:1000 (fig 2c). J Physiol (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study mouse models of dilated cardiomyopathy to study calcium signaling, Invitrogen ATP2A2 antibody (Affinity BioReagents, MA3-919) was used in western blot on mouse samples (fig 10). PLoS ONE (2016) ncbi |
mouse monoclonal (IID8) |
| In order to investigate the localization, processing, and protein interactome of the amyloid-beta protein precursor and its proteolytic products in mitochondria-associated membranes, Invitrogen ATP2A2 antibody (Thermo Fisher, IID8) was used in western blot on human samples (fig 1b). J Alzheimers Dis (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to test if modulation of SERCA2 improves outcome in sepsis, Invitrogen ATP2A2 antibody (Thermo Fischer, MA3-919) was used in immunohistochemistry on mouse samples at 1:200 (fig 4a) and in western blot on mouse samples at 1:200 (fig 4c). Sci Rep (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to test if BGP-15 ameliorate established disease in a mouse model of Duchenne muscular dystrophy, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on mouse samples (fig 4c). Am J Pathol (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to discuss how mutations in sarcomere genes may result in altered calcium signaling and heart defects, Invitrogen ATP2A2 antibody (Thermo Pierce, MA3-919) was used in western blot on human samples at 1:1000 (fig 1a). Circulation (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to determine the role of protein O-GlcNAcylation in skeletal muscle, Invitrogen ATP2A2 antibody (Thermo, MA3-919) was used in western blot on rat samples (fig 8). Physiol Rep (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to characterize engineered heart tissues derived from human induced pluripotent stem cell-derived cardiomyocytes, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on human samples at 1:1000 (fig s2). Stem Cell Reports (2016) ncbi |
mouse monoclonal (IID8) |
| In order to test if SERCA2a gene transfer reduces doxorubicin-induced cardiomyopathy, Invitrogen ATP2A2 antibody (Thermo Scientific, IID8) was used in western blot on human samples (fig 1b). J Gene Med (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study slow-twitch type 1 muscle fibers and diaphragm assessment in mice overexpressing phospholamban, Invitrogen ATP2A2 antibody (Pierce Antibodies, 2A7-A1) was used in western blot on mouse samples at 1:2000 (fig 1). Brain Behav (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to investigate left ventricular cardiomyocytes from post-infaction rats with and without heart failure after beta-adrenoceptor stimulation to revela Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion, Invitrogen ATP2A2 antibody (Thermo Fisher Scientific, MA3-919) was used in western blot on rat samples at 1:2500 (fig s1). PLoS ONE (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to elucidate the induction by phosphorylation-mediated ubiquitination and inhibition by interaction with cardiac type Sarco(endo)plasmic reticulum Ca(2+)-ATPase due to phospholamban degradation, Invitrogen ATP2A2 antibody (Affinity BioReagents, 2A7-A1) was used in western blot on human samples (fig 3). Biochem Biophys Res Commun (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to elucidate how DWORF activates the SERCA pump, Invitrogen ATP2A2 antibody (Pierce, 2A7-A1) was used in western blot on mouse samples at 1:2000 (fig s8a). Science (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to assess the importance of SERCA2a to the fibrotic response in small and large myocardial infarct, Invitrogen ATP2A2 antibody (Fisher Scientific, MA3- 919) was used in western blot on sheep samples (fig 1). J Thorac Cardiovasc Surg (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study the effects of ascending aortic banding on calcium handling in rat isolated atrial myocytes, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on rat samples (fig 2). PLoS ONE (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to determine the impact of ALDH2 overexpression on doxorubicin-induced myocardial damage and mitochondria, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in western blot on mouse samples (fig 4). Biochim Biophys Acta (2016) ncbi |
mouse monoclonal (IID8) |
| In order to examine the effect of palmitic acid exposure on HUVEC-CS cells, Invitrogen ATP2A2 antibody (Thermo Scientific Pierce, MA3-910) was used in western blot on human samples (fig 2). Cell Signal (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study SERCA dysfunction in mice overexpressing phospholamban, Invitrogen ATP2A2 antibody (Pierce Antibodies, 2A7-A1) was used in western blot on mouse samples and in western blot on human samples . Dis Model Mech (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to determine the relationship between ACE and ACE2 activity, left ventricular function, and gender in spontaneously hypertensive rats, Invitrogen ATP2A2 antibody (Affinity BioReagents, MA3-919) was used in western blot on rat samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to investigate the mechanism by which cysteine-rich free radical scavenger metallothionein regulates ER stress-induced myocardial contractile defect, Invitrogen ATP2A2 antibody (Affinity BioReagent, MA3- 919) was used in western blot on mouse samples (fig 3.e,f). Free Radic Res (2015) ncbi |
mouse monoclonal (IID8) |
| In order to study PDE3 in human cardiac myocytes, Invitrogen ATP2A2 antibody (Affinity Bioreagents, MA3-910) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study the role and mechanism of nitric oxide on Ca(2+) release, Invitrogen ATP2A2 antibody (thermo, ma3-919) was used in western blot on human samples . Arch Biochem Biophys (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study the effect of progesterone on SERCA2a regulation in isolated cardiomyocytes, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in immunoprecipitation on rabbit samples and in western blot on rabbit samples . Am J Physiol Cell Physiol (2014) ncbi |
mouse monoclonal (2A7-A1) |
| In order to suggest that the inability to enhance myofilament relaxation through cTnI phosphorylation predisposes the heart to hypertrophic cardiomyopathy, Invitrogen ATP2A2 antibody (Pierce, MA3-919) was used in western blot on mouse samples (fig 6). J Biol Chem (2014) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study the contribution of nuclear Ca(2+) handling on the development and progression of heart failure, Invitrogen ATP2A2 antibody (Thermo Scientific, MA3-919) was used in immunocytochemistry on mouse samples , in immunohistochemistry on mouse samples , in western blot on human samples , in immunocytochemistry on rabbit samples and in immunohistochemistry on rabbit samples . Circulation (2014) ncbi |
mouse monoclonal (2A7-A1) |
| In order to elucidate the critical role of TRPV2 in maintenance of cardiac function and structure in mice, Invitrogen ATP2A2 antibody (Thermo, MA3919) was used in western blot on mouse samples at 1:1000 (fig 6f). Nat Commun (2014) ncbi |
mouse monoclonal (2A7-A1) |
| In order to determine if sarcolipin and phospholamban regulate SERCA1a, SERCA2a, or both in skeletal muscle, Invitrogen ATP2A2 antibody (Pierce, 2A7-A1) was used in immunohistochemistry - frozen section on human samples at 1:1000 (fig 4), in immunoprecipitation on human samples (fig 6) and in western blot on human samples at 1:2000 (fig 3). PLoS ONE (2013) ncbi |
mouse monoclonal (2A7-A1) |
| In order to quantify the relative contribution of calcium cycling to resting metabolic rate in mouse fast and slow twitch skeletal muscle, Invitrogen ATP2A2 antibody (Affinity Bioreagents, 2A7-A1) was used in western blot on mouse samples (fig 7). PLoS ONE (2013) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study the cardiac effects of neuregulin in cMLCK knockout mice, Invitrogen ATP2A2 antibody (Pierce, MA3-919) was used in western blot on mouse samples . PLoS ONE (2013) ncbi |
mouse monoclonal (2A7-A1) |
| In order to investigate the abnormalities of calcium handling proteins in skeletal and heart muscle during heart failure, Invitrogen ATP2A2 antibody (Pierce, 2A7-A1) was used in western blot on human samples . J Card Fail (2012) ncbi |
mouse monoclonal (IID8) |
| Invitrogen ATP2A2 antibody (Affinity Bioreagents, MA3-910) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 and in immunocytochemistry on mouse samples at 1:1,000. J Comp Neurol (2008) ncbi |
Abcam
mouse monoclonal (IID8) |
| Abcam ATP2A2 antibody (Abcam, Ab2817) was used in western blot on human samples at 1:20 (fig 2a). Neuropathol Appl Neurobiol (2018) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on human samples (fig 4b). Mol Syst Biol (2017) ncbi |
mouse monoclonal (IID8) |
| In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam ATP2A2 antibody (Abcam, ab2817) was used in immunohistochemistry - paraffin section on rat samples at 1:50,000 (fig st14). J Toxicol Pathol (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to test if miR-133a is involved in the crosstalk between tyrosine hydroxylase and tyrosine aminotransferase in the diabetic heart, Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on rat samples at 1:1000 (fig 2e). Diabetes (2016) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in immunoprecipitation on mouse samples (fig 3) and in western blot on mouse samples (fig 3). Front Physiol (2016) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on rat samples at 1:1000 (fig 3). Cell Death Dis (2016) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in immunocytochemistry on human samples at 1:50 (fig 4) and in western blot on human samples at 1:1000 (fig 3). Skelet Muscle (2015) ncbi |
mouse monoclonal (2A7-A1) |
| In order to examine the interaction between store-operated calcium entry and store content and its role in cardiac pacemaking, Abcam ATP2A2 antibody (Abcam, ab2861) was used in immunocytochemistry on mouse samples at 1:500 (tbl 1). Front Physiol (2015) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, 2A7-A1) was used in immunohistochemistry on rat samples at 1:200 (fig 4). BMC Physiol (2014) ncbi |
mouse monoclonal (2A7-A1) |
| In order to study acute in vivo contraction in rat hindlimb and the higher level of PLIN5 and not PLIN3 in isolated skeletal muscle mitochondria, Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on rat samples at 1:1000 (fig 2). Physiol Rep (2014) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on mouse samples at 1:500. Am J Physiol Cell Physiol (2014) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in western blot on rat samples at 1:1000. Tissue Eng Part A (2014) ncbi |
mouse monoclonal (2A7-A1) |
| Abcam ATP2A2 antibody (Abcam, ab2861) was used in immunocytochemistry on mouse samples and in immunohistochemistry on mouse samples . PLoS ONE (2013) ncbi |
Novus Biologicals
mouse monoclonal (IID8) |
| Novus Biologicals ATP2A2 antibody (Novus Biologicals, NB300-529) was used in immunohistochemistry on human samples (fig 7c). Autophagy (2017) ncbi |
Enzo Life Sciences
mouse monoclonal (IID8) |
| Enzo Life Sciences ATP2A2 antibody (BioMol, IID8) was used in western blot on human samples (fig 3). Neuropathol Appl Neurobiol (2014) ncbi |
MilliporeSigma
mouse monoclonal (IID8) |
| MilliporeSigma ATP2A2 antibody (Sigma Aldrich, S-1439) was used in western blot on rat samples (fig 8b). Int J Cardiol (2017) ncbi |
mouse monoclonal (2A7-A1) |
| In order to report that PABPN1 regulates crucial processes during myotube formation, MilliporeSigma ATP2A2 antibody (Sigma, 2A7-A1) was used in immunocytochemistry on mouse samples (fig 7). J Physiol (2017) ncbi |
mouse monoclonal (IID8) |
| In order to explore how the crosstalk between calcium signaling and the MAPK pathway through the regulation of PMCA4b regulates metastasis, MilliporeSigma ATP2A2 antibody (Sigma, S1439) was used in western blot on human samples at 1:2500 (fig 1b). Int J Cancer (2017) ncbi |
mouse monoclonal (IID8) |
| MilliporeSigma ATP2A2 antibody (Sigma-Aldrich, s1439) was used in western blot on rat samples at 1:1000 (fig 3). Exp Ther Med (2016) ncbi |
mouse monoclonal (2A7-A1) |
| In order to maintain cardiac function through a heterozygous deletion of sarcolipin, MilliporeSigma ATP2A2 antibody (Sigma, S1314) was used in western blot on mouse samples (fig 3). Am J Physiol Heart Circ Physiol (2016) ncbi |
mouse monoclonal (2A7-A1) |
| MilliporeSigma ATP2A2 antibody (Sigma Aldrich S.A, S1314) was used in immunocytochemistry on mouse samples at 1:50 (fig 3). J Mol Cell Cardiol (2015) ncbi |
Badrilla
rabbit polyclonal |
| In order to investigate the deficiency that affects SERCA expression and function in the skeletal muscle by Calpain 3, Badrilla ATP2A2 antibody (Badrilla, A010-20) was used in proximity ligation assay on human samples at 1:100 (fig 6) and in immunohistochemistry - frozen section on human samples at 1:100 (fig 3). Expert Rev Mol Med (2016) ncbi |
rabbit polyclonal |
| Badrilla ATP2A2 antibody (Badrilla, A010-20) was used in western blot on rat samples at 1:5000 (fig 4b). PLoS ONE (2015) ncbi |
rabbit polyclonal |
| In order to investigate how PHD2 and PHD3 modulate contractile function, Badrilla ATP2A2 antibody (Badrilla, A010-20) was used in western blot on mouse samples (fig 1b). J Clin Invest (2015) ncbi |
rabbit polyclonal |
| In order to study the contribution of nuclear Ca(2+) handling on the development and progression of heart failure, Badrilla ATP2A2 antibody (Badrilla, A010-20) was used in immunohistochemistry on mouse samples and in immunohistochemistry on rabbit samples . Circulation (2014) ncbi |
rabbit polyclonal |
| In order to compare calcium uptake of the sarcoplasmic reticulum between type I and type II fibers of vastus lateralis muscle of young healthy adults, Badrilla ATP2A2 antibody (Badrilla, A010-2) was used in western blot on human samples at 1:5000 (fig 1a). J Physiol (2014) ncbi |
rabbit polyclonal |
| In order to ascertain the relationship between sarcoplasmic reticulum calcium content and calsequestrin isoforms in human skeletal muscle, Badrilla ATP2A2 antibody (Badrilla, A010-2) was used in western blot on human samples at 1:5000. J Physiol (2013) ncbi |
EMD Millipore
mouse monoclonal (IID8) |
| EMD Millipore ATP2A2 antibody (Millipore, MAB2636) was used in immunohistochemistry - frozen section on chicken samples at 1:1000 (tbl 1) and in western blot on chicken samples at 1:1000 (tbl 1). J Comp Neurol (2017) ncbi |
mouse monoclonal (IID8) |
| EMD Millipore ATP2A2 antibody (Millipore, MAB2636) was used in immunocytochemistry on human samples . PLoS ONE (2014) ncbi |
Articles Reviewed
- Helms A, Alvarado F, Yob J, Tang V, Pagani F, Russell M, et al. Genotype-Dependent and -Independent Calcium Signaling Dysregulation in Human Hypertrophic Cardiomyopathy. Circulation. 2016;134:1738-1748 pubmed
- Hortemo K, Lunde P, Anonsen J, Kvaløy H, Munkvik M, Rehn T, et al. Exercise training increases protein O-GlcNAcylation in rat skeletal muscle. Physiol Rep. 2016;4: pubmed
- Gong H, Li Y, Wang L, Lv Q, Wang X. Short-term effects of ?2-AR blocker ICI 118,551 on sarcoplasmic reticulum SERCA2a and cardiac function of rats with heart failure. Exp Ther Med. 2016;12:1355-1362 pubmed
- Sadredini M, Danielsen T, Aronsen J, Manotheepan R, Hougen K, Sjaastad I, et al. Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure. PLoS ONE. 2016;11:e0153887 pubmed publisher
- Gustavo Vazquez Jimenez J, Chavez Reyes J, Romero Garcia T, Zarain Herzberg A, Valdes Flores J, Manuel Galindo Rosales J, et al. Palmitic acid but not palmitoleic acid induces insulin resistance in a human endothelial cell line by decreasing SERCA pump expression. Cell Signal. 2016;28:53-9 pubmed publisher
- Revuelta López E, Cal R, Herraiz Martínez A, De Gonzalo Calvo D, Nasarre L, Roura S, et al. Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes. J Mol Cell Cardiol. 2015;85:25-36 pubmed publisher
- Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
- Dweck D, Sanchez Gonzalez M, Chang A, Dulce R, Badger C, Koutnik A, et al. Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy. J Biol Chem. 2014;289:23097-111 pubmed publisher
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