This is a Validated Antibody Database (VAD) review about dog AGFG1, based on 48 published articles (read how Labome selects the articles), using AGFG1 antibody in all methods. It is aimed to help Labome visitors find the most suited AGFG1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
AGFG1 synonym: HRB; arf-GAP domain and FG repeats-containing protein 1; arf-GAP domain and FG repeat-containing protein 1; HIV-1 Rev binding protein

Knockout validation
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig 3c
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 3c). Proc Natl Acad Sci U S A (2017) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig 1h
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 1h). J Clin Invest (2017) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot; mouse; loading ...; fig 3d
  • western blot knockout validation; human; loading ...; fig 4d
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610458) was used in western blot on mouse samples (fig 3d) and in western blot knockout validation on human samples (fig 4d). Cell Death Differ (2017) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4b
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot knockout validation on human samples at 1:1000 (fig 4b). Cell Death Dis (2017) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig s4a
  • immunoprecipitation; mouse; loading ...; fig 2a
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot knockout validation on mouse samples (fig s4a) and in immunoprecipitation on mouse samples (fig 2a). Nature (2016) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; fig 9
BD Biosciences AGFG1 antibody (BD biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 9). Nat Commun (2015) ncbi
BD Biosciences
mouse monoclonal (38/RIP)
  • western blot; human; fig 3f
BD Biosciences AGFG1 antibody (BD, 610458) was used in western blot on human samples (fig 3f). Cell Death Differ (2018) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; loading ...; fig 3b
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot on mouse samples (fig 3b). Cell Death Dis (2018) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; loading ...; fig 2b
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot on mouse samples (fig 2b). Nature (2018) ncbi
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig 3c
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 3c). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig 1h
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 1h). J Clin Invest (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; loading ...; fig 8b
  • western blot; mouse; loading ...; fig 6g
BD Biosciences AGFG1 antibody (BD Bioscience, 610459) was used in western blot on human samples (fig 8b) and in western blot on mouse samples (fig 6g). EMBO J (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; loading ...; fig s3
In order to test if TRAIL/TRAIL-R signaling in cancer cells alters the immune microenvironment, BD Biosciences AGFG1 antibody (BD Bioscience, 610458) was used in western blot on human samples (fig s3). Mol Cell (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; loading ...; fig 3d
  • western blot knockout validation; human; loading ...; fig 4d
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610458) was used in western blot on mouse samples (fig 3d) and in western blot knockout validation on human samples (fig 4d). Cell Death Differ (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4b
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot knockout validation on human samples at 1:1000 (fig 4b). Cell Death Dis (2017) ncbi
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; loading ...; fig s4a
  • immunoprecipitation; mouse; loading ...; fig 2a
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot knockout validation on mouse samples (fig s4a) and in immunoprecipitation on mouse samples (fig 2a). Nature (2016) ncbi
mouse monoclonal (38/RIP)
  • immunoprecipitation; mouse; fig 4
  • western blot; mouse; fig 1
In order to elucidate the mechanism by which RIPK1 counteracts RIPK3-MLKL-mediated necroptosis, BD Biosciences AGFG1 antibody (BD, 610459) was used in immunoprecipitation on mouse samples (fig 4) and in western blot on mouse samples (fig 1). Nature (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; loading ...; fig s1b
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples (fig s1b). Open Biol (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; 1:1000; fig s15
BD Biosciences AGFG1 antibody (BD Transduction, 610458) was used in western blot on human samples at 1:1000 (fig s15). Nat Commun (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; fig 1
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot on human samples (fig 1). Cell Rep (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; fig 5
BD Biosciences AGFG1 antibody (BD, 610458) was used in western blot on human samples (fig 5). EMBO J (2016) ncbi
mouse monoclonal (38/RIP)
  • immunoprecipitation; mouse; loading ...; fig s1
  • western blot; mouse; loading ...; fig 2a
BD Biosciences AGFG1 antibody (BD, 610458) was used in immunoprecipitation on mouse samples (fig s1) and in western blot on mouse samples (fig 2a). Cell Death Differ (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 5
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples (fig 5). Cell Rep (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; fig 2
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on human samples (fig 2). Biochem Biophys Res Commun (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 1
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples (fig 1). Cell Rep (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 6j
BD Biosciences AGFG1 antibody (BD, 610459) was used in western blot on mouse samples (fig 6j). Immunity (2016) ncbi
mouse monoclonal (38/RIP)
  • proximity ligation assay; mouse; fig 7
  • western blot; mouse; 1:1000; fig 8
  • proximity ligation assay; human; fig 7
  • western blot; human; 1:1000; fig 6
BD Biosciences AGFG1 antibody (BD Bioscience, 610459) was used in proximity ligation assay on mouse samples (fig 7), in western blot on mouse samples at 1:1000 (fig 8), in proximity ligation assay on human samples (fig 7) and in western blot on human samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 7
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples (fig 7). Nat Commun (2016) ncbi
mouse monoclonal (38/RIP)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences AGFG1 antibody (BD, 38) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 3
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on mouse samples (fig 3). Cell Death Dis (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; rat; 1:1000; fig 3
In order to investigate the molecular mechanisms that regulate cardiomyocyte necroptosis, BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on rat samples at 1:1000 (fig 3). Nat Med (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; 1:500; fig 6
In order to characterize TAK1 and modulation of skeletal muscle repair and satelline stem cell homeostasis, BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on mouse samples at 1:500 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (38/RIP)
  • immunocytochemistry; human; fig s9
  • western blot; human; fig 5b
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in immunocytochemistry on human samples (fig s9) and in western blot on human samples (fig 5b). Oncotarget (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
  • western blot; mouse
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on human samples and in western blot on mouse samples . Cell Death Differ (2016) ncbi
mouse monoclonal (38/RIP)
  • western blot knockout validation; mouse; fig 9
BD Biosciences AGFG1 antibody (BD biosciences, 610459) was used in western blot knockout validation on mouse samples (fig 9). Nat Commun (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; loading ...; fig 3f
BD Biosciences AGFG1 antibody (Becton, Dickinson, 610459) was used in western blot on mouse samples (fig 3f). Cell Death Differ (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples . Cell Death Dis (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; loading ...; fig 1a,2a,3
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610458) was used in western blot on human samples (fig 1a,2a,3). BMC Cancer (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human; fig 4a
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on human samples (fig 4a). Cell Commun Signal (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; 1:2000; fig 4
In order to study TLR3-mediated pro-inflammatory cytokine production regulated by glycogen synthase kinase 3-beta ubiquitination by TRAF6, BD Biosciences AGFG1 antibody (BD Pharmingen, 610459) was used in western blot on mouse samples at 1:2000 (fig 4). Nat Commun (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
In order to determine the role of PCTAIRE1 in apoptosis, BD Biosciences AGFG1 antibody (BD Transduction Lab, 610458) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; 1:1000; fig 2
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples at 1:1000 (fig 2). Front Cell Dev Biol (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; 1:1000; fig 5
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Cell Biol (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; 1:1000; fig 4e
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610458) was used in western blot on mouse samples at 1:1000 (fig 4e). Nat Commun (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
In order to investigate if Chal-24 can be combined with cisplatin for better cancer therapy, BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples . Oncotarget (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 2
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610459) was used in western blot on mouse samples (fig 2). Cell Death Dis (2015) ncbi
mouse monoclonal (38/RIP)
  • immunoprecipitation; mouse; fig 2a
  • western blot; mouse; fig 2d
BD Biosciences AGFG1 antibody (BD Transduction Laboratories, 610458) was used in immunoprecipitation on mouse samples (fig 2a) and in western blot on mouse samples (fig 2d). Apoptosis (2015) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse; fig 3
In order to show that RIPK1 regulates homeostasis and prevents inflammation in barrier tissues by inhibiting epithelial cell apoptosis and necroptosis, BD Biosciences AGFG1 antibody (BDBiosciences, 610459) was used in western blot on mouse samples (fig 3). Nature (2014) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse
BD Biosciences AGFG1 antibody (BD Biosciences, 610459) was used in western blot on mouse samples . Biomed Res Int (2014) ncbi
mouse monoclonal (38/RIP)
  • western blot; mouse
BD Biosciences AGFG1 antibody (BD, 610458) was used in western blot on mouse samples . J Immunol (2014) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
In order to study the role of receptor-interacting protein 1 in cancer's response to chemotherapy, BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
In order to identify a novel anticancer mechanism that functions through autophagy-mediated necroptosis, BD Biosciences AGFG1 antibody (BD Biosciences, 610458) was used in western blot on human samples . Oncogene (2014) ncbi
mouse monoclonal (38/RIP)
  • western blot; human
BD Biosciences AGFG1 antibody (BD Bioscience, 610458) was used in western blot on human samples . Mol Cancer Res (2013) ncbi
Articles Reviewed
  1. Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2018;: pubmed publisher
  2. Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed publisher
  3. Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
  4. Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
  5. Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed publisher
  6. Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
  7. Hartwig T, Montinaro A, von Karstedt S, Sevko A, Surinova S, Chakravarthy A, et al. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2. Mol Cell. 2017;65:730-742.e5 pubmed publisher
  8. Tanzer M, Khan N, Rickard J, Etemadi N, Lalaoui N, Spall S, et al. Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ. 2017;24:481-491 pubmed publisher
  9. Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed publisher
  10. Newton K, Wickliffe K, Maltzman A, Dugger D, Strasser A, Pham V, et al. RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016;540:129-133 pubmed publisher
  11. Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  12. Samson A, Ho B, Au A, Schoenwaelder S, Smyth M, Bottomley S, et al. Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells. Open Biol. 2016;6: pubmed
  13. Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
  14. Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed publisher
  15. Wagner S, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes. EMBO J. 2016;35:1868-84 pubmed publisher
  16. Shutinoski B, Alturki N, Rijal D, Bertin J, Gough P, Schlossmacher M, et al. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo. Cell Death Differ. 2016;23:1628-37 pubmed publisher
  17. Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  18. Emmerich C, Bakshi S, Kelsall I, Ortiz Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-461 pubmed publisher
  19. Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
  20. Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed publisher
  21. Orme M, Liccardi G, Moderau N, Feltham R, Wicky John S, Tenev T, et al. The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nat Commun. 2016;7:10972 pubmed publisher
  22. Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher
  23. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  24. Jacobsen A, Lowes K, Tanzer M, Lucet I, Hildebrand J, Petrie E, et al. HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death. Cell Death Dis. 2016;7:e2051 pubmed publisher
  25. Zhang T, Zhang Y, Cui M, Jin L, Wang Y, Lv F, et al. CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis. Nat Med. 2016;22:175-82 pubmed publisher
  26. Ogura Y, Hindi S, Sato S, Xiong G, Akira S, Kumar A. TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair. Nat Commun. 2015;6:10123 pubmed publisher
  27. Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, et al. Sorafenib-induced defective autophagy promotes cell death by necroptosis. Oncotarget. 2015;6:37066-82 pubmed publisher
  28. Yoon S, Bogdanov K, Kovalenko A, Wallach D. Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it. Cell Death Differ. 2016;23:253-60 pubmed publisher
  29. Kang S, Fernandes Alnemri T, Rogers C, Mayes L, Wang Y, Dillon C, et al. Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nat Commun. 2015;6:7515 pubmed publisher
  30. Boutaffala L, Bertrand M, Remouchamps C, Seleznik G, Reisinger F, Janas M, et al. NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis. Cell Death Differ. 2015;22:2020-33 pubmed publisher
  31. Fauster A, Rebsamen M, Huber K, Bigenzahn J, Stukalov A, Lardeau C, et al. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. Cell Death Dis. 2015;6:e1767 pubmed publisher
  32. Selmi T, Alecci C, dell Aquila M, Montorsi L, Martello A, Guizzetti F, et al. ZFP36 stabilizes RIP1 via degradation of XIAP and cIAP2 thereby promoting ripoptosome assembly. BMC Cancer. 2015;15:357 pubmed publisher
  33. Philipp S, Sosna J, Plenge J, Kalthoff H, Adam D. Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis. Cell Commun Signal. 2015;13:25 pubmed publisher
  34. Ko R, Park J, Ha H, Choi Y, Lee S. Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nat Commun. 2015;6:6765 pubmed publisher
  35. Yanagi T, Shi R, Aza Blanc P, Reed J, Matsuzawa S. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PLoS ONE. 2015;10:e0119404 pubmed publisher
  36. Dowling J, Nair A, Zhang J. A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis. Front Cell Dev Biol. 2015;3:12 pubmed publisher
  37. Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, et al. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 2015;17:434-44 pubmed publisher
  38. Lawlor K, Khan N, Mildenhall A, Gerlic M, Croker B, D Cruz A, et al. RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat Commun. 2015;6:6282 pubmed publisher
  39. Shi S, Wang Q, Xu J, Jang J, Padilla M, Nyunoya T, et al. Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. Oncotarget. 2015;6:1640-51 pubmed
  40. Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher
  41. Saveljeva S, Mc Laughlin S, Vandenabeele P, Samali A, Bertrand M. Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells. Cell Death Dis. 2015;6:e1587 pubmed publisher
  42. Chen G, Cheng X, Zhao M, Lin S, Lu J, Kang J, et al. RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells. Apoptosis. 2015;20:92-109 pubmed publisher
  43. Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed publisher
  44. Liu S, Wang X, Li Y, Xu L, Yu X, Ge L, et al. Necroptosis mediates TNF-induced toxicity of hippocampal neurons. Biomed Res Int. 2014;2014:290182 pubmed publisher
  45. McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S. Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase. J Immunol. 2014;192:5671-8 pubmed publisher
  46. Wang Q, Shi S, He W, Padilla M, Zhang L, Wang X, et al. Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition. Oncotarget. 2014;5:1304-14 pubmed
  47. He W, Wang Q, Srinivasan B, Xu J, Padilla M, Li Z, et al. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. Oncogene. 2014;33:3004-13 pubmed publisher
  48. Han J, Soletti R, Sadarangani A, Sridevi P, Ramirez M, Eckmann L, et al. Nuclear expression of ?-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res. 2013;11:207-18 pubmed publisher